This very special issue of Expert Opinion on Biological Therapy illustrates the dramatic impact biologics have had on the treatment of psoriasis. Psoriasis is a chronic disease with manifold presentations. Biologics have affected almost every nook and cranny of psoriasis treatment. This issue reviews short- and long-term treatment, use in different psoriasis subpopulations, cost of treatment, and impact of comorbidities, including COVID-19, on patients receiving biologics for psoriasis. While ‘hand holding’ and psychosocial support used to be the most important thing we could offer patients with horrible psoriasis, we now can clear the disease in most patients, nearly clear it in others, and do so with a minimum of risk. Biologics have thoroughly changed the management of this disease, restoring normal quality of life to patients who had been suffering.
Of course, this is only the beginning. We look forward to atopic dermatitis and the rest of dermatology to be transformed by the biologic revolution.
Declaration of interest
S Feldman has received research, speaking and/or consulting support from Eli Lilly and Company, GlaxoSmithKline/Stiefel, AbbVie, Janssen, Alovtech, vTv Therapeutics, Bristol-Myers Squibb, Samsung, Pfizer, Boehringer Ingelheim, Amgen, Dermavant, Arcutis, Novartis, Novan, UCB, Helsinn, Sun Pharma, Almirall, Galderma, Leo Pharma, Mylan, Celgene, Ortho Dermatology, Menlo, Merck & Co, Qurient, Forte, Arena, Biocon, Accordant, Argenx, Sanofi, Regeneron, the National Biological Corporation, Caremark, Teladoc, BMS, Ono, Micreos, Eurofins, Informa, UpToDate and the National Psoriasis Foundation. He is founder and part owner of Causal Research and holds stock in Sensal Health. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
Correction Statement
This article has been republished with minor changes. These changes do not impact the academic content of the article.