ABSTRACT
The goal was to determine ways to optimize diagnostic and therapeutic measures for various types of melasma in the outpatient setting of the dermatovenerological ambulatory clinic. The study involved 112 women with a confirmed diagnosis of facial melasma whose disease lasted for at least 2 years. The severity of patient pigmentation was evaluated using the Melasma Area Severity Index and the Melasma Severity Scale. There was a significant increase in melanin levels across all melasma types, an increase in erythema in the dermal type, and an increase in sebum production in the epidermal type.
Disclosure statement
No potential conflict of interest was reported by the authors.
Declaration of Conflicting Interests
The authors declared no potential conflicts of interest concerning the research, authorship, and/or publication of this article.
Data availability statement
Data is avaible at https://drive.google.com/drive/u/2/my-drive
Ethical approval
The study protocol was approved by the Ethics Committee of I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation. The study was conducted by the rules of the Declaration of Helsinki.
Informed consent
All subjects gave written informed consent before participation.