Supervised exercises have superior effects compared to home-based exercises for patients with knee osteoarthritis following platelet-rich plasma injection

ABSTRACT

The purpose of the study was to compare the effectiveness of physiotherapist-supervised and home-based exercises after platelet-rich-plasma (PRP) injection in knee osteoarthritis (OA). Thirty women (mean age = 57.83 ± 7.26 years; mean weight = 72.13 ± 15.54 kg; mean height = 158.40 ± 4.49 cm; mean body mass index = 28.75 ± 6.18 kg/m²) were included. Patients randomized either supervised or home-basedexercise-group after PRP. Both groups performed 6-week (3 times/week) exercise. Pain, hip and knee muscle strength, and knee functions were assessed before and after exercise. The median improvement in the pain from baseline to 6^th week was 3.80 (2.85–5.55) point in-supervised-exercise-group while it was 0.60 (−0.10–2.55) point in home-based-exercise-group (p = 0.002). The median improvement in knee function was 22.91 (13.02–30.20) in supervised-exercise-group overtime (p < 0.001). There was no improvement in knee function following home-based exercises (p = 1.000). The supervised-exercise-group revealed a significant improvement in hip (median difference = 32.00 (8.30–88.95), p = 0.011); quadriceps (median difference = 32.10 (21.65–60.05), p = 0.001) and hamstring (median difference = 27.90 (7.95–37.65), p = 0.022) strength overtime. The physiotherapist-supervised exercises after PRP had better effects on pain and knee function than the home-based exercises.

KEYWORDS:

• Knee osteoarthritis
• exercise
• platelet-rich plasma
• pain

Disclosure statement

No potential conflict of interest was reported by the author(s).

Ethics committee

Lokman Hekim University Ethics Committee (2021/049).

ClinicalTrials.gov registration number

NCT05033977.

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.