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BIOMEDICINE

Antibacterial Properties of Au-Ag Alloy Nanoparticles

, &
Pages 489-494 | Received 21 Jun 2012, Accepted 26 Aug 2012, Published online: 20 Mar 2013
 

ABSTRACT

This article reports a preliminary study on the effect of alloying on the antibacterial properties of silver and gold. Au-Ag alloy nanoparticles were synthesized in water by coreduction of the metal salts by sodium borohydride in the presence of sodium citrate as a capping agent. The particle morphology and size were studied by transmission electron microscopy. The Au-Ag (1:1) particles were 4 ± 1 nm with good monodispersity. The formation of alloy was concluded by spectrophotometry in the visible region complemented by energy-dispersive spectroscopy (EDS). The antibacterial activity of the particles was examined against Escherichia coli ATCC 25922. Interestingly, the alloy particles exhibited greater antibacterial activities than the pure metals. The antibacterial property of the alloy nanoparticles was further enhanced with an increasing molar ratio of silver.

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