A case of polyangiitis overlap syndrome of giant cell arteritis and granulomatosis with polyangiitis successfully treated with rituximab

Abstract

We report a case of polyangiitis overlap syndrome of giant cell arteritis (GCA) and granulomatosis with polyangiitis (GPA) and conduct a literature review of polyangiitis overlap syndrome. The patient was 73-year-old male who developed cranial-type GCA and GPA simultaneously and was successfully treated with rituximab. Rituximab might be effective for not only GPA but also GCA.

Keywords:

• Giant cell arteritis
• Granulomatosis with polyangiitis
• anti-neutrophil cytoplasmic antibody-associated vasculitis
• polyangiitis overlap
• rituximab

Ethical approval

Not applicable.

Patient consent

We have received this patient’s written informed consent for publication.

Conflict of interest

KA has received a research grant from Asahi Kasei Pharma and speaking fees from AbbVie GK, Chugai Pharmaceutical Co. Ltd., Eli Lilly, Mitsubishi Tanabe Pharma, and Pfizer Japan.

The other authors declare no conflict of interest.