Defining 5-MeO-DMT in Historical and Cultural Contexts

References

• 5-MeO-DMT Malpractice (n.d). Open letter concerning abuses by Octavio Rettig and Gerry Sandoval. https://5-meo-dmt-malpractice.org/open-letter-concerning-abuses-by-octavio-rettig-and-gerry-sandoval/
   Google Scholar
• Araújo, A. M., Carvalho, F., de Lourdes Bastos, M., Guedes de Pinho, P., & Carvalho, M. (2015). The hallucinogenic world of tryptamines: An updated review. Archives of Toxicology, 89(8), 1151–1173. https://doi.org/10.1007/s00204-015-1513-x
   PubMed Web of Science ®Google Scholar
• Ball, M. W. (2017). Entheogenic liberation: Unraveling the enigma of nonduality with 5-MeO-DMT energetic therapy. CreateSpace Independent Publishing Platform.
   Google Scholar
• Barker, S. A. (2018). N, N-dimethyltryptamine (DMT), an endogenous hallucinogen: Past, present, and future research to determine its role and function. Frontiers in Neuroscience, 12, 536. https://doi.org/10.3389/fnins.2018.00536
   PubMed Web of Science ®Google Scholar
• Barsuglia, J., Davis, A. K., Palmer, R., Lancelotta, R., Windham-Herman, A.-M., Peterson, K., Polanco, M., Grant, R., & Griffiths, R. R. (2018). Intensity of mystical experiences occasioned by 5-MeO-DMT and comparison with a prior psilocybin study. Frontiers in Psychology, 9, 2459. https://doi.org/10.3389/fpsyg.2018.02459
   PubMed Web of Science ®Google Scholar
• Baudouin, G., Tillequin, F., Koch, M., Pusset, J., & Sêvenet, T. (1981). Plantes de Nouvelle-Calédonie. LXXIII. Alcaloïdes de Dutaillyea oreophila et de Dutaillyea drupacea [Plants of New Caledonia. LXXIII. Alkaloids of Dutaillyea oreophila and Dutaillyea drupacea]. Journal of Natural Products, 44(5), 546–550. https://doi.org/10.1021/np50017a006
   Google Scholar
• Botta, S. (2013). La ausencia de los dioses taínos. Sobre el fracaso hermenéutico de la obra de Ramón Pané [The absence of the Taino gods. On the hermeneutic failure of Ramón Pané’s work]. Latinoamérica. Revista de Estudios Latinoamericanos, 57, 161–187. https://doi.org/10.1016/s1665-8574(13)71716-2
   Google Scholar
• Bourne, E. G. (1906). Columbus, Ramón Pané and the Beginnings of American Anthropology. Worcester. Retrieved from the Library of Congress, https://www.loc.gov/item/20020150/
   Google Scholar
• Bye, R. A. (1979). Hallucinogenic plants of the Tarahumara. Journal of Ethnopharmacology, 1(1), 23–48. https://doi.org/10.1016/0378-8741(79)90015-1
   PubMed Web of Science ®Google Scholar
• Christian, S. T., Benington, F., Morin, R. D., & Corbett, L. O. (1975). Gas-liquid chromatographic separation and identification of biologically important indolealkylamines from human cerebrospinal fluid. Biochemical Medicine, 14(2), 191–200. https://doi.org/10.1016/0006-2944(75)90036-8
   PubMedGoogle Scholar
• Clement, B. A., Goff, C. M., & Forbes, T. D. A. (1998). Toxic amines and alkaloids from Acacia rigidula. Phytochemistry, 49(5), 1377–1380. https://doi.org/10.1016/S0031-9422(97)01022-4
   Web of Science ®Google Scholar
• Coe, M. D. (1966). The Maya. Thames & Hudson.
   Google Scholar
• The Conclave (2019). A recommended model for best practices. The Conclave. https://theconclave.info
   Google Scholar
• Davis, J. (1998). Transpersonal dimensions of ecopsychology: Nature, nonduality, and spiritual practice. The Humanistic Psychologist, 26(1-3), 69–100. https://doi.org/10.1080/08873267.1998.9976967
   Google Scholar
• Davis, A. K., Barsuglia, J. P., Lancelotta, R., Grant, R. M., & Renn, E. (2018). The epidemiology of 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT) use: Benefits, consequences, patterns of use, subjective effects, and reasons for consumption. Journal of Psychopharmacology (Oxford, England), 32(7), 779–792. https://doi.org/10.1177/0269881118769063
   PubMed Web of Science ®Google Scholar
• Davis, W., & Weil, A. T. (1992). Identity of a new world psychoactive toad. Ancient Mesoamerica, 3(1), 51–59. https://doi.org/10.1017/s095653610000229
   Google Scholar
• de las Casas, B., & Castelló, V. A. (1992). Apologética historia sumaria [Apologetic summary history]. Alianza.
   Google Scholar
• de Rios, M. D., Alger, N., Crumrine, N. R., Furst, P. T., Harman, R. C., Hellmuth, N. M., Hopkins, N. A., King, W. C., Koss, J. D., La Barre, W., Landar, H. J., Long, J. K., Proskouriakoff, T., Rubel, A. J., Samaranch, F. J., & Wescott, R. W. (1974). The influence of psychotropic flora and fauna on Maya. Current Anthropology, 15(2), 147–164. https://doi.org/10.1086/201452
   Web of Science ®Google Scholar
• Drug Enforcement Agency. (2009). Schedules of controlled substances: Placement of 5-methoxy-N, N-dimethyltryptamine into Schedule I of the Controlled Substances Act. Federal Register, 74(161), 42217–42220.
   Google Scholar
• Ermakova, A. O., Dunbar, F., Rucker, J., & Johnson, M. W. (2021). A narrative synthesis of research with 5-MeO-DMT. Journal of Psychopharmacology (Oxford, England), 36(3), 273–294. https://doi.org/10.1177/02698811211050543
   PubMed Web of Science ®Google Scholar
• Erspamer, V., Vitali, T., Roseghini, M., & Cei, J. M. (1967). 5-Methoxy- and 5-Hydroxyindoles in the skin of Bufo alvarius. Biochemical Pharmacology, 16(7), 1149–1164. https://doi.org/10.1016/0006-2952(67)90147-5
   PubMed Web of Science ®Google Scholar
• Feliks, Y. (1994). Fruit trees in the bible and Talmudic literature. Rubin Mass Press.
   Google Scholar
• Fundacion Ramon Pane (2020, December 13). Documentary of the first evangelizer of America, Ramón Pané [Video]. YouTube. https://www.youtube.com/watch?v=k1cImFbBt0k
   Google Scholar
• Gómez Álvarez, G., Reyes Gómez, S. R., Teutli Solano, C., & Valadez-Azúa, R. (2007). La medicina tradicional Prehispánica, vertebrados terrestres y productos medicinales de tres mercados del Valle de México [Pre-Hispanic traditional medicine, terrestrial vertebrates and medicinal products from three markets in the Valley of Mexico]. Etnobiología, 5(1), 86–98.
   Google Scholar
• Grinspoon, L., & Bakalar, J. B. (1998). Psychedelic drugs reconsidered (2nd ed.). The Lindesmith Centre.
   Google Scholar
• Grof, S. (1985). Beyond the brain: Birth, death and transcendence in psychotherapy. State University of New York Press.
   Google Scholar
• Grof, S. (2006). When the impossible happens. Sounds True.
   Google Scholar
• Hamblin, N. L. (1981). The magictoads of Cozumel. Mexicon, 3(1), 10–14.
   Google Scholar
• Hinojosa, O. R. (2016). The toad at dawn. Divine Arts.
   Google Scholar
• Hoshino, T., & Shimodaira, K. (1935). Synthese des bufotenins und über 3-methyl-3-β-oxyäthyl-indolenin. Synthesen in der indol-gruppe. XIV [Synthesis of bufotenine and 3-methyl-3-β-oxyethyl-indolenin. Syntheses in the indole group]. Justus Liebigs Annalen der Chemie, 520(1), 19–30. https://doi.org/10.1002/jlac.19355200104
   Google Scholar
• Horák, M., Segovia, E. M., & Bello, A. C. (2019). Bufo alvarius: Evidencias literarias y controversias en torno a su uso tradicional [Bufo alvarius: Literary evidence and controversies surrounding its traditional use]. Medicina naturista, 13(1), 43–49.
   Google Scholar
• Instituto Nacional para la Evaluación de le Educación México (2014). Comca’ac: Desemboque de los Seris, Pitiquito, Sonora: Consulta previa, libre e informada a pueblos y comunidades indígenas sobre la evaluación educativa. [Comca’ac: Desemboque de los Seris, Pitiquito, Sonora: Free, prior and informed consultation with indigenous peoples and communities on educational evaluation]. Instituto Nacional para la Evaluación de le Educación México. https://www.inee.edu.mx/wp-content/uploads/2019/02/Consulta-Desemboque.pdf
   Google Scholar
• Janick, J. (2007). Fruits of the bibles. HortScience, 42(5), 1072–1076. https://doi.org/10.21273/HORTSCI.42.5.1072
   Web of Science ®Google Scholar
• Jensen, B. (2019, Summer). Treating depression with a psychedelic found in toad venom. John Hopkins Magazine. https://hub.jhu.edu/magazine/2019/summer/toad-venom-therapy/
   Google Scholar
• Kargbo, R. B. (2021). 5-MeO-DMT: Potential use of psychedelic-induced experiences in the treatment of psychological disorders. ACS Medicinal Chemistry Letters, 12(11), 1646–1648. https://doi.org/10.1021/acsmedchemlett.1c00546
   PubMedGoogle Scholar
• Kaye, Q. (1999). Intoxicant use in the prehistoric Caribbean with particular reference to spouted ceramic inhaling bowls. Papers from the Institute of Archaeology, 10, 55–73. https://doi.org/10.5334/pia.136
   Google Scholar
• Keen, B. (Trans.). (1959). The life of the Admiral Christopher Columbus by his son Ferdinand. The Folio Society.
   Google Scholar
• Kennedy, T. J., Christian, D. R., & Khan, J. I. (2011). Basic principles of forensic chemistry. Humana Press.
   Google Scholar
• Lawlor, S. (2019, November 20). 5-MeO-DMT: Light and shadow in the psychedelic toad. Psychedelic Times. https://psychedelictimes.com/5-meo-dmt-psychedelic-toad/
   Google Scholar
• Liana, L. (2019). Bufo deaths & fraud involving toad “shamans” Octavio Rettig & Gerry Sandoval. EntheoNation. https://entheonation.com/blog/death-fraud-octavio-rettig-gerry-sandoval/
   Google Scholar
• Lozoya, X. (1983). Sobre la investigación de las plantas psicotrópicas en las antiguas culturas indígenas de México [On the research of psycho-tropical plants in the ancient indigenous cultures of Mexico]. Estudios de la Cultura Náhuatl, 16, 193–206.
   Google Scholar
• Lucious, H., & Ball, M., [EntheogenicEvolution]. (2023, January 5). A conversation with Hal from the Temple of Awakening Divinity [Video]. YouTube. https://www.youtube.com/watch?v=GFHPn_KvBMk
   Google Scholar
• Mackey, A. G. (2017). The symbolism of Freemasonry: Illustrating and explaining its science and philosophy, its legends, myths and symbols. Pinnacle Press.
   Google Scholar
• Malcolm, B. (2022, May 26). Mechanisms of psychedelic tryptamines: 5-MeO-DMT vs. classics. Spirit Pharmacist. https://www.spiritpharmacist.com/blog/psychedelicmechanisms5vclassics
   Google Scholar
• MAPS. (2019, April 4). James Oroc: The new psychedelic revolution: Culture wars, 5-MeO-DMT, and beyond (No. 39) [Audio podcast episode]. In The MAPS podcast. MAPS. https://maps.org/2019/04/04/maps-podcast-episode-39-james-oroc-the-new-psychedelic-revolution/
   Google Scholar
• Marlett, S. A. (2018). The Seris and the Comcaac: Sifting fact from fiction about the names and relationships. Work Papers of the Summer Institute of Linguistics, University of North Dakota Session, 51(1), 1–20. https://doi.org/10.31356/silwp.vol51.01
   Google Scholar
• McDonald, J. A., & Stross, B. (2012). Water lily and cosmic serpent: Equivalent conduits of the Maya spirit realm. Journal of Ethnobiology, 32(1), 74–107. https://doi.org/10.2993/0278-0771-32.1.74
   Web of Science ®Google Scholar
• McKenna, T. K. (1993). Food of the gods. Bantam.
   Google Scholar
• Metzner, R. (2013a). Entheogenic rituals, shamanism and green psychology. European Journal of Ecopsychology, 4, 64–77.
   Google Scholar
• Metzner, R. (2013b). The toad and the jaguar: A field report of underground research on a visionary medicine Bufo alvarius and 5-methoxy-dimethyltryptamine. Green Earth Foundation.
   Google Scholar
• Metzner, R. (2017). Ecology of consciousness: The alchemy of personal, collective, and planetary transformation. Reveal Press.
   Google Scholar
• Meyer, K., & Linde, H. H. (1971). Collection of toad venoms and chemistry of the toad venom steroids. In W. Bücherl & E. E. Buckley (Eds.), Venomous animals and their venoms (pp. 521–556). Academic Press. https://doi.org/10.1016/B978-0-12-138902-4.50027-1
   Google Scholar
• Most, A. (1984). Bufo alvarius: The psychedelic toad of the Sonoran Desert. Venom Press.
   Google Scholar
• Muraresku, B. C. (2020). The immortality key: The secret history of the religion with no name. St. Martin’s Press.
   Google Scholar
• Oroc, J. (2006). Tryptamine palace. Park Street Press.
   Google Scholar
• Ortiz Bernal, A. M. (2022, December 16). Reflections on how the Yaqui intercultural medicine clinic came to be. Points. https://www.pointshistory.com/post/strong-reflections-on-how-the-yaqui-intercultural-medicine-clinic-a-unique-model-of-community-wel
   Google Scholar
• Ott, J. (2001). Shamanic snuffs or entheogenic errhines. Entheobotanica.
   Google Scholar
• Palamar, J. J., & Le, A. (2018). Trends in DMT and other tryptamine use among young adults in the United States. The American Journal on Addictions, 27(7), 578–585. https://doi.org/10.1111/ajad.12803
   PubMed Web of Science ®Google Scholar
• Pané, R. (1999). An account of the antiquities of the Andians: Chronicles of the New World encounter (J. J. Arrom, Ed.; S. C. Griswold, Trans.). Duke University Press. (Original work published 1496)
   Google Scholar
• Pollan, M. (2018). How to change your mind: What the new science of psychedelics teaches us about consciousness, dying, addiction, depression, and transcendence. Penguin Books.
   Google Scholar
• Reckweg, J. T., Uthaug, M. V., Szabo, A., Davis, A. K., Lancelotta, R., Mason, N. L., & Ramaekers, J. G. (2022). The clinical pharmacology and potential therapeutic applications of 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT). Journal of Neurochemistry, 162(1), 128–146. https://doi.org/10.1111/jnc.15587
   PubMed Web of Science ®Google Scholar
• Révész, D., Ona, G., Rossi, G. N., Rocha, J. M., dos Santos, R. G., Hallak, J. E. C., Alcázar-Córcoles, M. Á., & Bouso, J. C. (2021). Cross-sectional associations between lifetime use of psychedelic drugs and psychometric measures during the COVID-19 confinement: A transcultural study. Frontiers in Psychiatry, 12, 687546. https://doi.org/10.3389/fpsyt.2021.687546
   PubMed Web of Science ®Google Scholar
• Robiou Lamarche, S. (2006). Mitología y religion de los Taínos [Mythology and religion of the Tainos]. Editorial Punto Y Coma.
   Google Scholar
• Rodriguez Alvarez, A. (2008). Mitología taína o eyeri, Ramón Pané y la relación sobre las antigüedades de Los Indios: El primer tratado etnográfico hecho en América. Editorial Nuevo Mundo.
   Google Scholar
• Salazar, A. M. G. (2022, December 15). Sonoran desert toad secretions may have therapeutic uses, says Mexican psychologist. El Pais. https://english.elpais.com/science-tech/2022-12-15/sonoran-desert-toad-secretions-may-have-therapeutic-uses-says-mexican-psychologist.html
   Google Scholar
• Sandoval, G. R. (2016). The god molecule. Divine Arts.
   Google Scholar
• Schultes, R. E., & Hofmann, A. (1992). Plants of the gods: Their sacred, healing, and hallucinogenic powers. Healing Arts Press.
   Google Scholar
• Serna, M. (2022). Ramón pané como el primer informador de las hierbas y enfermedades de los indios. Hipogrifo. Revista De Literatura y Cultura Del Siglo De Oro, 10(2), 607–618. https://doi.org/10.13035/h.2022.10.02.37
   Google Scholar
• Shanon, B. (2008). Biblical entheogens: A speculative hypothesis. Time and Mind: The Journal of Archaeology, Consciousness, and Culture, 1(1), 51–74. https://doi.org/10.2752/175169608783489116
   Google Scholar
• Shepard, G. H. Jr. (2005). Psychoactive botanicals in ritual, religion, and shamanism. In E. Elisabetsky & N. Etkin (Eds.), Encyclopedia of life support systems. UNESCO/EOLSS Publishers. https://www.eolss.net/
   Google Scholar
• Shulgin, A. T., & Shulgin, A. (2007). Pihkal: A chemical love story. Transform Press.
   Google Scholar
• Siebert, A. (2022, January 8). Hamilton Morris on mistakes, 5-MeO-DMT and preserving psychedelic toads. Forbes. https://www.forbes.com/sites/amandasiebert/2021/01/08/hamilton-morris-on-mistakes-5-meo-dmt-and-preserving-psychedelic-toads/
   Google Scholar
• Smith, T. A. (1977). Tryptamine and related compounds in plants. Phytochemistry, 16(2), 171–175. https://doi.org/10.1016/S0031-9422(00)86778-3
   Web of Science ®Google Scholar
• Strassman, R. (2001). DMT: The spirit molecule: A doctor’s revolutionary research into the biology of near-death and mystical experiences. Park Street Press.
   Google Scholar
• Tallis, R. (2006). Myths, medicine, and meaning. The Lancet, 367(9517), 1135–1136. https://doi.org/10.1016/S0140-6736(06)68493-6
   Google Scholar
• Torres, C. M., & Repke, D. B. (2006). Anadenanthera: Visionary plant of ancient South America. Haworth Herbal Press.
   Google Scholar
• Trout, K. (2007). Some simple tryptamines (2nd ed.). Mydriatic Productions.
   Google Scholar
• Uthaug, M. V., Lancelotta, R., Ortiz Bernal, A. M., Davis, A. K., & Ramaekers, J. G. (2020a). A comparison of reactivation experiences following vaporization and intramuscular injection (IM) of synthetic 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) in a naturalistic setting. Journal of Psychedelic Studies, 4(2), 104–113. https://doi.org/10.1556/2054.2020.00123
   Google Scholar
• Uthaug, M. V., Lancelotta, R., Szabo, A., Davis, A. K., Riba, J., & Ramaekers, J. G. (2020b). Prospective examination of synthetic 5-methoxy-N,N-dimethyltryptamine inhalation: Effects on salivary IL-6, cortisol levels, affect, and non-judgment. Psychopharmacology, 237(3), 773–785. https://doi.org/10.1007/s00213-019-05414-w
   PubMed Web of Science ®Google Scholar
• Uthaug, M. V., Lancelotta, R., van Oorsouw, K., Kuypers, K. P. C., Mason, N., Rak, J., Šuláková, A., Jurok, R., Maryška, M., Kuchař, M., Páleníček, T., Riba, J., & Ramaekers, J. G. (2019). A single inhalation of vapor from dried toad secretion containing 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) in a naturalistic setting is related to sustained enhancement of satisfaction with life, mindfulness-related capacities, and a decrement of psychopathological symptoms. Psychopharmacology, 236(9), 2653–2666. https://doi.org/10.1007/s00213-019-05236-w
   PubMed Web of Science ®Google Scholar
• Vail, G., & Aveni, A. F. (2004). The Madrid codex: New approaches to understanding an ancient Maya manuscript. University Press of Colorado.
   Google Scholar
• Vice TV. (2017, November 28). Hamilton Morris learns about the toad ceremonies of the Yaqui Tribe [Video]. YouTube. https://www.youtube.com/watch?v=M5U9D7Y5er4
   Google Scholar
• Weil, A. T., & Davis, W. (1994). Bufo alvarius: A potent hallucinogen of animal origin. Journal of Ethnopharmacology, 41(1-2), 1–8. https://doi.org/10.1016/0378-8741(94)90051-5
   PubMed Web of Science ®Google Scholar
• Westrum, R., & Dufrechou, J. (2021). The psychedelics integration handbook. Ryan P. Westrum & Jay P. Dufrechou.
   Google Scholar
• Winkelman, M. J. (2013). Shamanism and psychedelics: A biogenetic structuralist paradigm of ecopsychology. European Journal of Ecopsychology, 4, 90–91.
   Google Scholar
• Winkelman, M. J. (2017). The mechanisms of psychedelic visionary experiences: Hypotheses from evolutionary psychology. Frontiers in Neuroscience, 11, 539. https://doi.org/10.3389/fnins.2017.00539
   PubMed Web of Science ®Google Scholar
• Wittliff, J. L. (1962). Parotoid gland secretions in two species groups of toads (genus Bufo). Evolution, 16(2), 143–153. https://doi.org/10.2307/2406193
   Web of Science ®Google Scholar