Comparative Subchronic Inhalation Study of Smoke From the 1R4F and 2R4F Reference Cigarettes

REFERENCES

• Ayres P. H., Mosberg A. T., Coggins C. R. E.. 1990. Modernization of nose-only smoking machines for use in animal inhalation studies. J. Am. Coll. Toxicol.. 9: 441–446. [CSA]
   Google Scholar
• Ayres P. H., Hayes J. R., Higuchi M. A., Mosberg A. T., Sagartz J. W.. 2001. Subchronic inhalation by rats of mainstream smoke from a cigarette that primarily heats tobacco compared to a cigarette that burns tobacco. Inhal. Toxicol.. 13: 149–186. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Baumgartner H., Coggins C. R. E.. 1980. Description of a continuous-smoking inhalation machine for exposing small animals to tobacco smoke. Beitr. Tabakforsch. Int.. 10: 169–174
   Web of Science ®Google Scholar
• Borgerding M. F., Bodnar J. A., Chung H. L., Mangan P. P., Morrison C. C., Risner C. H., Rodgers J. C., Simmons D. F., Uhrig M. S., Wendelboe F. N., Wingate D. E., Winkler L. S.. 1997. Chemical and biologiclal studies of a new cigarette that primarily heats tobacco. Part 1: Chemical composition of mainstream smoke. Food Chem. Toxicol.
   Web of Science ®Google Scholar
• Coggins C. R., Fouillet X. L., Lam R., Morgan K. T.. 1980. Cigarette smoke induced pathology of the rat respiratory tract: A comparison of the effects of the particulate and vapour phases. Toxicology. 16: 83–101. [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Coggins C. R. E., Duchosal F., Musy C., Ventrone R.. 1981. The measurement of respiratory patterns in rodents, using whole body plethysmography and a pneumotachograph. Lab. Anim.. 15: 137–140. [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Coggins C. R. E., Lam R., Morgan K. T.. 1982. Chronic inhalation study in rats using cigarettes containing different amounts of Cytrel tobacco supplement. Toxicology. 22: 287–296. [CSA], [CROSSREF]
   Web of Science ®Google Scholar
• Coggins C. R. E., Ayres P. H., Mosberg A. T., Sagartz J. W., Burger G. T., Hayes A. W.. 1989a. Ninety-day inhalation study in rats, comparing smoke from cigarettes that heat tobacco with those that burn tobacco. Fundam. Appl. Toxicol.. 13: 460–483. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Coggins C. R. E., Ayres P. H., Mosberg A. T., Burger G. T., Sagartz J. W., Hayes A. W.. 1989b. Comparative inhalation study in rats, using a second prototype of a cigarette that heats rather than burns tobacco. Inhal. Toxicol.. 1: 197–226. [CSA]
   Google Scholar
• Davies H. M., Vaught A.. 2002; The reference cigarette, Internal publication (original publication date 1990). Kentucky Tobacco Research and Development Center, University of Kentucky, Lexington
   Google Scholar
• Davis D. L., Vaught A., Tso T. C., Bush L. P.. 1984; Analyses of a new lower yield research cigarette, Presented at the 8th International Scientific Tobacco Scientists' Conference of CORESTA. ViennaAustria, October 7–12.
   Google Scholar
• Davis R. A., Stiles M. F.. 1993; Determination of nicotine and cotinine: Comparison of GC and radioimmunoassay methods, Presented at the 47th Tobacco Chemist Research Conference. Gatlinburg, TN, October 18–21.
   Google Scholar
• Dixon M., Lambing K., Seeman J. I.. 2000. On the transfer of nicotine from tobacco to the smoker. A brief review of ammonia and “pH” factors. Beitr. Tabakforsch. Int.. 19: 103–113
   Google Scholar
• Feldman D. B., Seely J. C.. 1988; Necropsy guide: Rodent and rabbit,. pp. 1–50, Boca Raton, FL, CRC Press
   Google Scholar
• Gaworski C. L., Dozier M. M., Gerhart J. M., Rajendran N., Brennecke L. H., Arany C., Heck J. D.. 1997. 13-Week inhalation toxicity study of menthol cigarette smoke. Food Chem. Toxicol.. 35: 683–692. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Gaworski C. L., Dozier M. M., Heck J. D., Gerhart J. M., Rajendran N., David R. M., Brennecke L. H., Morrissey R.. 1998. Toxicologic evaluation of flavor ingredients added to cigarette tobacco: 13-Week inhalation exposures in rats. Inhal. Toxicol.. 10: 357–381. [CROSSREF]
   Web of Science ®Google Scholar
• Institute of Laboratory Animal Resources, 1996; Guide for the care and use of laboratory animals. Washington, DC, Commission on Life Sciences, National Research Council, National Academy Press
   Google Scholar
• Kinsler S., Pence D. H., Shreve W. K., Mosberg A. T., Ayres P. H., Sagartz J. W.. 2003. Rat subchronic inhalation study of smoke from cigarettes containing flue-cured tobacco cured either by direct-fired or heat-exchanger curing processes. Inhal. Toxicol.. 15: 819–854. [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Sagartz J. W., Madarasz A. J., Forsell M. A., Burger G. T., Ayres P. H., Coggins C. R. E.. 1992. Histologic sectioning of the rodent larynx for inhalation toxicity testing. Toxicol. Pathol.. 20: 118–121. [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Siegel S.. 1956; Non-parametric statistics for the behavioral sciences. New York, McGraw-Hill
   Google Scholar
• Stavanja M. S, Ayres P. H., Meckley D. R., Bombick B. R., Pence D. H., Borgerding M. F., Morton M. J., Mosberg A. T., Swauger J. E.. 2003. Toxicological evaluation of honey as an ingredient added to cigarette tobacco. J. Toxicol. Environ. Health A. 66(15)1453–1474. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Theophilus E. H., Poindexter D. B., Meckley D. R., Bombick B. R., Borgerding M. F., Higuchi M. A., Ayres P. H., Morton M. J., Mosberg A. T., Swauger J. E.. 2003a. Toxicological evaluation of dry ice expanded tobacco. Toxicol. Lett.. 145(2)107–119. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Theophilus E. H., Bombick B. R., Meckley D. R., Higuchi M. A., Borgerding M. F., Morton M. J., Mosberg A. T., Swauger J. E.. 2003b. Toxicological evaluation of propane expanded tobacco. Food Chem. Toxicol.. 41: 1771–1780. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Van, Vunakis H., Gjika B. B., Langone J. J.. 1987. Method 16, Radioimmunoassay for nicotine and cotinine. Environmental carcinogens: Methods of analysis and exposure,. Vol. 9, I. K., O'Neill, K. D., Brunnemann, B., Dodet, D., Hoffman, Lyon, International Agency for Research on Cancer. pp. 317–330
   Google Scholar
• Young J. T.. 1981. Histopathologic examination of the rat nasal cavity. Fundam. Appl. Toxicol.. 1: 309–312. [PUBMED], [INFOTRIEVE]
   PubMedGoogle Scholar