Long Term Consequences from Exposure to Sulfur Mustard: A Review

REFERENCES

• Aghanouri R., Ghanei M., Aslani J., Keivani-Amine H., Rastegar F., Karkhane A. Fibrogenic cytokine levels in bronchoalveolar lavage aspirates 15 years after exposure to sulfur mustard. Am. J. Physiol. Lung Cell. Mol. Physiol 2004; 287(6)L1160–Lii64
   PubMed Web of Science ®Google Scholar
• Ardi-Bazar M., Ansarin K. H. Effect of corticosteroid on restrictive lung disorder in MG exposed patients. Proc. First International Medical Congress of Chemical Warfare, Mashhad, Iran, 1988; 62
   Google Scholar
• Bagheri M. H., Hosseini S. K., Mostafavi S. H., Alavi S. A. High-resolution CT in chronic pulmonary changes after mustard gas exposure. Acta Radiol. 2003; 44(3)241–245
   PubMedGoogle Scholar
• Balali M. Clinical and laboratory findings in Iranian fighters with chemical gas poisoning. Proceedings of the first world congress on new compounds in biological and chemical warfare: Toxicological evaluation, A. Heyndrickx. Ghent University Press, Ghent 1984; 254
   Google Scholar
• Balali M., Hefazi M. The pharmacology, toxicology, and medical treatment of sulphur mustard poisoning. Fundam. Clin. Pharmacol. 2005; 19(3)297–315
   PubMedGoogle Scholar
• Beheshti J., Mark E. J., Akbari H., Ghanei M. Mustard lung secrets: Long term clinicopathological study following mustard gas exposure. Pathol. Res. Pract. 2006; 202(10)739–744
   PubMed Web of Science ®Google Scholar
• Bijani K., Moghadamnia A. A. Long-term effects of chemical weapons on respiratory tract in Iraq–Iran war victims living in Babol (North of Iran). Ecotoxicol. Environ. Saf. 2002; 53(3)422–424
   PubMed Web of Science ®Google Scholar
• Bjoraker J. A., Ryu J. H., Edwin M. K., Myers J. L., Tazelaar H. D., Schroeder D. R., Offord K. P. Prognostic significance of histopathologic subsets in idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med 1998; 157(1)199–203
   PubMed Web of Science ®Google Scholar
• Blanc P. D. The legacy of war gas. Am. J. Med. 1999; 106: 689–690
   PubMedGoogle Scholar
• Borak J., Sidell F. R. Agents of chemical warfare: Sulfur mustard. Ann. Emerg. Med. 1992; 21(3)303–308
   PubMed Web of Science ®Google Scholar
• Chuang M. T., Raskin J., Krellenstein D. J., Teirstein A. S. Bronchoscopy in diffuse lung disease: Evaluation by open lung biopsy in nondiagnostic transbronchial lung biopsy. Ann. Otol. Rhinol. Laryngol. 1987; 96(6)654–657
   PubMedGoogle Scholar
• Costabel U., King T. E. International consensus statement on idiopathic pulmonary fibrosis. Eur. Respir. J. 2001; 17: 163–167
   PubMedGoogle Scholar
• Dacre J. C., Goldman M. Toxicology and pharmacology of the chemical warfare agent sulfur mustard. Pharmacol. Rev. 1996; 48: 289–326
   PubMed Web of Science ®Google Scholar
• Dompeling E., Jobsis Q., Vandevijver N. M., Wesseling G., Hendriks H. Chronic bronchiolitis in a 5-yr-old child after exposure to sulphur mustard gas. Eur. Respir. J. 2004; 23(2)343–346
   PubMed Web of Science ®Google Scholar
• Easton D. F., Peto J., Doll R. Cancers of the respiratory tract in mustard gas workers. Br. J. Ind. Med. 1988; 45(10)652–659
   PubMedGoogle Scholar
• El-Gamel A., Sim E., Hasleton P., Yonan N., Egan J., Campbell C., Rahman A., Sheldon S., Deiraniya A., Hutchinson I. V. Transforming growth factor beta (TGF-beta) and obliterative bronchiolitis following pulmonary transplantation. J. Heart Lung Transplant. 1999; 18(9)828–837
   PubMed Web of Science ®Google Scholar
• Elkin S. L., Nicholson A. G., du Bois R. M. Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung disease. Semin. Respir. Crit. Care Med. 2001; 22: 387–398
   PubMedGoogle Scholar
• Ellison D. H. Handbook of chemical and biological warfare agents. CRC Press, Boca Raton, FL 2000
   Google Scholar
• Emad A., Rezaian G. R. The diversity of effects of sulfur mustard gas inhalation on respiratory system 10 years after a single, heavy exposure: Analysis of 197 cases. Chest 1997; 112(3)734–738
   PubMed Web of Science ®Google Scholar
• Emad A., Rezaian G. R. Immunoglobulins and cellular constituents of the BAL fluid of patients with sulfur mustard gas-induced pulmonary fibrosis. Chest 1999; 115(5)1346–1351
   PubMedGoogle Scholar
• Emad A. F., Rezaian G. R., Hosseini K. L. Chronic pulmonary squeal of sulfur mustard gas exposure in man: A report of 36 cases. Iran J. Med. Sci. 1995; 20(1,2)1–4
   Google Scholar
• Freitag L., Firusian N., Stamatis G., Greschuchna D. The role of bronchoscopy in pulmonary complications due to mustard gas inhalation. Chest 1991; 100(6)1486
   PubMedGoogle Scholar
• Ghanei M., Abdolmaali K., Aslani J. Efficacy of concomitant administration of clarythromycin and acetylcysteine in bronchiolitis obliterans in seventeen sulfur mustard-exposed patients: An open-label study. Curr. Ther. Res. 2004a; 65(6)1–9
   PubMedGoogle Scholar
• Ghanei M., Akhlaghpoor S., Moahammad M. M., Aslani J. Tracheobronchial stenosis following sulfur mustard inhalation. Inhal. Toxicol. 2004b; 16(13)845–849
   PubMed Web of Science ®Google Scholar
• Ghanei M., Fathi H., Mohammad M. M., Aslani J., Nematizadeh F. Long-term respiratory disorders of claimers with subclinical exposure to chemical warfare agents. Inhal. Toxicol. 2004c; 16(8)491–495
   PubMed Web of Science ®Google Scholar
• Ghanei M., Mokhtari M., Mohammad M. M., Aslani J. Bronchiolitis obliterans following exposure to sulfur mustard: Chest high resolution computed tomography. Eur. J. Radiol. 2004d; 52(2)164–169
   PubMedGoogle Scholar
• Ghanei M., Hosseini K. A. R., ShahKarami E. Evaluation of chronic cough in chemical induced chronic bronchitis patients. J. Environ. Pathol. Toxicol. 2005a; 20(1)6–10
   Google Scholar
• Ghanei M., Khalili A. R., Arab M. J., Mojtahedzadeh M., Aslani J., Lessan-Pezeshki M., Panahi Y., Alaeddini F. Diagnostic and therapeutic value of short-term corticosteroid therapy in exacerbation of mustard gas-induced chronic bronchitis. Basic Clin. Pharmacol. Toxicol. 2005b; 97(5)302–305
   PubMed Web of Science ®Google Scholar
• Ghanei M., Harandi A. A., Rezaei F., Vasei A. Sinus CT scan findings in patients with chronic cough following sulfur mustard inhalation: A case-control study. Inhal. Toxicol. 2006a; 18(14)1135–1138
   PubMed Web of Science ®Google Scholar
• Ghanei M., Eshraghi M., Jalali A. R., Aslani J. Evaluation of latent hemoptysis in Sulfur Mustard injured patients. Environ. Toxicol. Pharmacol. 2006b; 22(2)128–130
   PubMedGoogle Scholar
• Ghanei M., Khedmat H., Mardi F., Hosseini A. Distal esophagitis in patients with mustard-gas induced chronic cough. Dis. Esophagus. 2006c; 19: 285–288
   PubMed Web of Science ®Google Scholar
• Ghanei M., Moqadam F. A., Mohammad M. M., Aslani J. Tracheobronchomalacia and air trapping after mustard gas exposure. Am. J. Respir. Crit. Care Med. 2006d; 173(3)304–309
   PubMedGoogle Scholar
• Ghanei M., Panahi Y., Mojtahedzadeh M., Khalili A. R., Aslani J. Effect of gamma interferon on lung function of mustard gas exposed patients, after 15 years. Pulmon. Pharmacol. Ther. 2006e; 19(2)148–153
   PubMedGoogle Scholar
• Ghotbi L., Hassan Z. The immunostatus of natural killer cells in people exposed to sulfur mustard. Int. Immunopharmacol. 2002; 28: 981–985
   Google Scholar
• Heidarnejad H., Zendehdel N., Dastgiri S. Temporal trend of clinical and spirometric parameters in mustard gas victims: A ten year study. Arch. Iran Med. 1988; 1(1)13–16
   Google Scholar
• Hefazi M., Attaran D., Mahmoudi M., Balali-Mood M. Late respiratory complications of mustard gas poisoning in Iranian veterans. Inhal. Toxicol. 2005; 17(11)587–592
   PubMed Web of Science ®Google Scholar
• Heston W. E. Induction of pulmonary tumors in strain A mice with methyl-bis(beta-chloroethyl) amine hydrochloride. J. Natl. Cancer Inst. 1949; 10: 125–130
   PubMedGoogle Scholar
• Hosseini K., Alavi S., Abedi A. R. Reversibility of airflow obstruction in chronic obstructive pulmonary disease secondary to sulfur mustard gas injury. Arch. Iran Med. 1999; 2(4)178–180
   Google Scholar
• Khateri S., Ghanei M., Keshavarz S., Soroush M., Haines D. Incidence of lung, eye, and skinlesions as late complications in 34,000 Iranians with wartime exposure to mustard agent. J. Occup. Environ. Med. 2003; 45(11)1136–1143
   PubMed Web of Science ®Google Scholar
• Manning K. P., Skegg D. C., Stell P. M., Doll R. Cancer of the larynx and other occupational hazards of mustard gas workers. Clin. Otolaryngol. 1981; 6(3)165–170
   PubMedGoogle Scholar
• Miller W. T., Jr., Kotloff R. M., Blumenthal N. P., Aronchick J. M., Gefter W. B., Miller W. T. Utility of high resolution computed tomography in predicting bronchiolitis obliterans syndrome following lung transplantation: Preliminary findings. J. Thorac. Imaging. 2001; 16(2)76–80
   PubMedGoogle Scholar
• Mirsadraee M., Attaran D., Boskabady M. H., Towhidi M. Airway hyperresponsiveness to methacholine in chemical warfare victims. Respiration 2005; 72(5)523–528
   PubMedGoogle Scholar
• Norman J. E., Jr. Lung cancer mortality in World War I veterans with mustard-gas injury: 1919–1965. J. Natl. Cancer Inst. 1975; 54(2)311–317
   PubMedGoogle Scholar
• Palombini B. C., Villanova C. A., Araujo E., Gastal O. L., Alt D. C., Stolz D. P., Palombini C. O. A pathogenic triad in chronic cough: Asthma, postnasal drip syndrome, and gastroesophageal reflux disease. Chest 1999; 116(2)279–284
   PubMedGoogle Scholar
• Paslawski M., Krzyzanowski K., Zlomaniec J. Typical findings for bronchiolitis in high resolution computed tomography. Ann. Univ. Mariae Curie Sklodowska 2004; 59(1)32–37
   PubMedGoogle Scholar
• Veterans at risk: The health effects of mustard gas and lewisite., C. M. Perchura, D. P. Rall. Institute of Medicine, Washington, DC 1993
   Google Scholar
• Prokes J., Svoboda V., Hynie I., Proksova M., Kacl K. The influence of x-radiation and mustard gas on methionin-35S incorporation in erythrocytes. Neoplasma 1968; 15(4)393–398
   PubMedGoogle Scholar
• Review of acute human-toxicity estimates for selected chemical-warfare agents. National Academy Press, Washington, DC 1997, National Research Council Committee on Toxicology Subcommittee on Toxicity Values for Selected Nerve and Vesicant Agents
   Google Scholar
• Saladi R. N., Smith E., Persaud A. N. Mustard: A potential agent of chemical warfare and terrorism. Clin. Exp. Dermatol. 2006; 31(1)1–5
   PubMed Web of Science ®Google Scholar
• Sandall T. E. The later effects of gas poisoning. Lancet 1922; 2: 857–859
   Google Scholar
• Security Council of the United Nations. Report of specialists appointed by the Secretary General to investigate allegations by the Islamic Republic of Iran concerning the use of chemical weapons. Security Council of United Nations, New York 1986, document S/16433/1986
   Google Scholar
• Shaker Z., Hassan Z. M., Sohrabpour H., Mosaffa N. The immunostatus of T helper and T cytotoxic cells in the patients 10 years after exposure to sulfur mustard. Immunopharmacol. Immunotoxicol. 2003; 25: 423–430
   PubMed Web of Science ®Google Scholar
• Sohrabpour H., Masjedi M. R., Bahadori M. Late complications of sulfur mustard in respiratory system. Med. J. Islam. Repub. Iran. 1988; 2(3)171–173
   Google Scholar
• Sohrabpour H., Roshan-Zamir F., Aminorroya A. P. Comparison of acute bronchodilatory effects of inhaled Sulbotamol and Combivent in mustard gas victims. Iran J. Med. Sci. 1996; 21(1, 2)34
   Google Scholar
• Chemical warfare agents: Toxicity at low levels., S. M. Somani, J. A. Romano. CRC Press, Boca Raton, FL 2001
   Google Scholar
• Stanbrook M. B., Kesten S. Bronchial hyperreactivity after lung transplantation predicts early bronchiolitis obliterans. Am. J. Respir. Crit. Care Med 1999; 160(6)2034–2039
   PubMedGoogle Scholar
• Takeshima Y., Inai K., Bennett W. P., Metcalf R. A., Welsh J. A., Yonehara S., Hayashi Y., Fujihara M., Yamakido M., Akiyama M. p53 mutations in lung cancers from Japanese mustard gas workers. Carcinogenesis 1994; 15(10)2075–2079
   PubMed Web of Science ®Google Scholar
• Thomason J. W., Rice T. W., Milstone A. P. Bronchiolitis obliterans in a survivor of a chemical weapons attack. J. Am. Med. Assoc. 2003; 290(5)598–599
   PubMed Web of Science ®Google Scholar
• Van Helden H. P., Kuijpers W. C., Diemel R. V. Asthma-like symptoms following intratracheal exposure of guinea pigs to sulfur mustard aerosol: Therapeutic efficacy of exogenous lung surfactant Curosurf and Salbutamol. Inhal. Toxicol. 2004; 16(8)537–548
   PubMedGoogle Scholar
• Wada S., Miyanishi M., Nishimoto Y., Kambe S., Miller R. W. Mustard gas as a cause of respiratory neoplasia in man. Lancet 1968; 1(7553)1161–1163
   PubMedGoogle Scholar
• Wall C. P., Gaensler E. A., Carrington C. B., Hayes J. A. Comparison of transbronchial and open biopsies in chronic infiltrative lung diseases. Am. Rev. Respir. Dis. 1981; 123(3)280–285
   PubMed Web of Science ®Google Scholar
• World Health Organization. Report of the mission Dispatched by the Secretary-General to investigate allegations of the use of chemical weapons in the conflict between Iran and Iraq. United Nations, New York 12 March, 1986, Report S/17911
   Google Scholar
• Yanagida J., Hozawa S., Ishioka S., Maeda H., Takahashi K., Oyama T., Takaishi M., Hakoda M., Akiyama M., Yamakido M. Somatic mutation in peripheral lymphocytes of former workers at the Okunojima Poison Gas Plants. Jpn. J. Thorac. Dis. 1988; 79: 1276–1283
   Google Scholar