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Inhalation Toxicology

International Forum for Respiratory Research

Volume 11, 1999 - Issue 6-7

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Research Article

THE USE OF TRANSGENIC ANIMALS IN CANCER TESTING

John E. French, Judson W. Spalding, June K. Dunnick, Raymond R. Tice, Marianna Furedi-Machacek, Raymond W. Tennant National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA; Integrated Laboratory Systems, Research Triangle Park, North Carolina, USA; National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA

Pages 541-544 | Published online: 01 Oct 2008

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https://doi.org/10.1080/089583799196925

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Donehower, L. A., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery, J. C. A., Butel, J. S., and Bradley, A. 1992. Mice deficient for p53 are developmentally normal but susceptible to sponta-neous tumors. Nature 356:215–221.
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Leder, A., Kuo, A., Cardiff, R. D., Sinn, E., and Leder, P. 1990. V-Ha-ras transgene abrogates the initi-ation step in the mouse skin tumorigenesis: Effects of phorbol esters and retinoic acid. Proc. Natl. Acad. Sci. USA 87:9178–9182.
PubMed Web of Science ®Google Scholar

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