Mixture of enzyme-processed Panax ginseng and Gastrodia elata extract prevents UVB-induced decrease of procollagen type 1 and increase of MMP-1 and IL-6 in human dermal fibroblasts

References

• Zhang S, Duan E. Fighting against skin aging: the way from bench to bedside. Cell Transplant. 2018;27(5):729–738.
   PubMed Web of Science ®Google Scholar
• Structure and Function of Skin. Biology for Majors II [Internet]. [cited 2019 Dec 23]. Available from: https://courses.lumenlearning.com/wmopen-biology2/chapter/structure-and-function-of-skin/.
   Google Scholar
• Arda O, Göksügür N, Tüzün Y. Basic histological structure and functions of facial skin. Clin Dermatol. 2014;32(1):3–13.
   PubMed Web of Science ®Google Scholar
• Lopez-Ojeda W, Pandey a, Alhajj M, et al. Anatomy, Skin (Integument). StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019. [cited 2019 Dec 26]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK441980/
   Google Scholar
• Boer M, Duchnik E, Maleszka R, et al. Structural and biophysical characteristics of human skin in maintaining proper epidermal barrier function. Adv Dermatol Allergol Dermatol Alergol. 2016;33:1–5.
   PubMed Web of Science ®Google Scholar
• Hwang E, Sun Z-W, Lee TH, et al. Enzyme-processed Korean Red Ginseng extracts protects against skin damage induced by UVB irradiation in hairless mice. J Ginseng Res. 2013;37(4):425–434.
   PubMed Web of Science ®Google Scholar
• Biniek K, Levi K, Dauskardt RH. Solar UV radiation reduces the barrier function of human skin. Proc Natl Acad Sci U S A. 2012;109(42):17111–17116.
   PubMed Web of Science ®Google Scholar
• D’Orazio J, Jarrett S, Amaro-Ortiz a, et al. UV Radiation and the Skin. Int J Mol Sci. 2013;14(6):12222–12248.
   PubMed Web of Science ®Google Scholar
• Kammeyer a, Luiten RM. Oxidation events and skin aging. Ageing Res Rev. 2015;21:16–29.
   PubMed Web of Science ®Google Scholar
• Shin J-W, Kwon S-H, Choi J-Y, et al. Molecular mechanisms of dermal aging and antiaging approaches. Int J Mol Sci [Internet]. 2019;20. [cited 2019 Dec 26]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540032/
   Web of Science ®Google Scholar
• Uitto J, Olsen DR, Fazio MJ. Extracellular matrix of the skin: 50 years of progress. J Invest Dermatol. 1989;92(4):61S–77S.
   PubMed Web of Science ®Google Scholar
• Watson REB, Gibbs NK, Griffiths CEM, et al. Damage to skin extracellular matrix induced by UV exposure. Antioxid Redox Signal. 2014;21(7):1063–1077.
   PubMed Web of Science ®Google Scholar
• Chermnykh E, Kalabusheva E, Vorotelyak E. Extracellular matrix as a regulator of epidermal stem cell fate. Int J Mol Sci [Internet]. 2018;19. [cited 2019 Dec 26]. Available from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979429/
   PubMed Web of Science ®Google Scholar
• Quan T, Qin Z, Xia W, et al. Matrix-degrading Metalloproteinases in Photoaging. J Investig Dermatol Symp Proc Soc Investig Dermatol Inc Eur Soc Dermatol Res. 2009;14(1):20–24.
   PubMedGoogle Scholar
• a comprehensive review of the therapeutic and pharmacological effects of ginseng and ginsenosides in central nervous system [Internet]. [cited 2019 Dec 26]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659622/.
   Google Scholar
• Kiefer D, Pantuso T. Panax ginseng. Am Fam Physician. 2003;68(8):1539–1542.
   PubMed Web of Science ®Google Scholar
• Rajabian a, Rameshrad M, Hosseinzadeh H. Therapeutic potential of Panax ginseng and its constituents, ginsenosides and gintonin, in neurological and neurodegenerative disorders: a patent review. Expert Opin Ther Pat. 2019;29(1):55–72.
   PubMed Web of Science ®Google Scholar
• Zheng M, Xu F, Li Y, et al. Study on transformation of ginsenosides in different methods. Bio Med Res Int [Internet]. 2017;2017. [cited 2019 Dec 26]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745656/
   Google Scholar
• Hwang E, Lee TH, Park S-Y, et al. Enzyme-modified Panax ginseng inhibits UVB-induced skin aging through the regulation of procollagen type I and MMP-1 expression. Food Funct. 2014;5(2):265–274. .
   PubMed Web of Science ®Google Scholar
• Huang G-B, Zhao T, Muna SS, et al. Therapeutic potential of Gastrodia elata Blume for the treatment of Alzheimer’s disease. Neural Regen Res. 2013;8(12):1061–1070.
   PubMed Web of Science ®Google Scholar
• Phenolic compounds from the rhizomes of Gastrodia elata. PubMed - NCBI [Internet]. [cited 2019 Dec 26]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/17613623.
   Google Scholar
• Hwang E, Ngo HTT, Yang J-E, et al. Evaluation of protective effect of cyclodextrin glucanotransferase-treated Gastrodia elata Blume extract on ultraviolet B-induced premature skin aging. Trop J Pharm Res. Kyung Hee University, Global Campus, Korea. 2019;17(10):1969 .
   Web of Science ®Google Scholar
• University-Industry Cooperation Group of Kyung Hee University. a enzyme having activities of transforming saponin in ginseng isolated from culture of Aspergillus niger, a method of manufacturing the same, a ginseng extract treated with the same, a method of manufacturing the ginseng extract and Composition comprising the ginseng extract for improving skin beauty. 2014.
   Google Scholar
• Hwang E, Park S-Y, Lee HJ, et al. Gallic acid regulates skin photoaging in UVB-exposed Fibroblast and Hairless Mice: PROTECTIVE EFFECTS OF GA AGAINST UVB-MEDIATED SKIN AGING. Phytother Res. 2014;28(12):1778–1788.
   PubMed Web of Science ®Google Scholar
• Afaq F, Mukhtar H. Photochemoprevention by botanical antioxidants. Skin Pharmacol Physiol. 2002;15(5):297–306.
   Web of Science ®Google Scholar
• Chen Q. Evaluate the effectiveness of the natural cosmetic product compared to chemical-based products. Int J Chem. 2009;1(2):57.
   Google Scholar
• Park S-H, Lee -S-S, Bang M-H, et al. Protection against UVB-induced damages in human dermal fibroblasts: efficacy of tricin isolated from enzyme-treated Zizania latifolia extract. Biosci Biotechnol Biochem. 2019;83(3):551–560. .
   PubMed Web of Science ®Google Scholar
• Protection against UVB-Induced Wrinkle Formation in SKH-1 Hairless mice: efficacy of tricin isolated from enzyme-treated zizania latifolia extract [Internet]. [cited 2020 Jul 6]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225172/.
   Google Scholar
• Yang J-E, Ngo HTT, Hwang E, et al. Dietary enzyme-treated Hibiscus syriacus L. protects skin against chronic UVB-induced photoaging via enhancement of skin hydration and collagen synthesis. Arch Biochem Biophys. 2019;662:190–200.
   PubMed Web of Science ®Google Scholar
• Cheng Y, Shen L, Zhang J. Anti-amnestic and anti-aging effects of ginsenoside Rg1 and Rb1 and its mechanism of action. Acta Pharmacol Sin. 2005;26(2):143–149.
   PubMed Web of Science ®Google Scholar
• Kim C-S, Jo Y-J, Park S-H, et al. Anti-stress effects of ginsenoside Rg 3 -standardized ginseng extract in restraint stressed animals. Biomol Ther. 2010;18(2):219–225. .
   Web of Science ®Google Scholar
• Choi JH, Lee MJ, Jang M, et al. Panax ginseng exerts antidepressant-like effects by suppressing neuroinflammatory response and upregulating nuclear factor erythroid 2 related factor 2 signaling in the amygdala. J Ginseng Res. 2018;42(1):107–115.
   PubMed Web of Science ®Google Scholar
• Quan FS, Compans RW, Cho Y-K, et al. Ginseng and Salviae herbs play a role as immune activators and modulate immune responses during influenza virus infection. Vaccine. 2007;25(2):272–282.
   PubMed Web of Science ®Google Scholar
• Hwang E, Ngo HTT, Park B, et al. Myrcene, an aromatic volatile compound, ameliorates human skin extrinsic aging via regulation of MMPs production. Am J Chin Med. 2017;45(5):1113–1124.
   PubMed Web of Science ®Google Scholar
• Vajragupta O, Boonchoong P, Berliner LJ. Manganese complexes of curcumin analogues: evaluation of hydroxyl radical scavenging ability, superoxide dismutase activity and stability towards hydrolysis. Free Radic Res. 2004;38(3):303–314.
   PubMed Web of Science ®Google Scholar
• Han S, Park -K-K, Chung W-Y, et al. Anti-photoaging effects of 2-methoxy-5-(2-methyl propyl) pyrazine isolated from peach (Prunus persica (L.) Batsch). Food Sci Biotechnol. 2010;19(6):1667–1671.
   Web of Science ®Google Scholar
• Afnan Q, Adil MD, Nissar-Ul a, et al. Glycyrrhizic acid (GA), a triterpenoid saponin glycoside alleviates ultraviolet-B irradiation-induced photoaging in human dermal fibroblasts. Phytomedicine Int J Phytother Phytopharm. 2012;19:658–664.
   PubMed Web of Science ®Google Scholar
• J-M L, Lin PH, Yao Q, et al. Chemical and molecular mechanisms of antioxidants: experimental approaches and model systems. J Cell Mol Med. 2010;14(4):840–860.
   PubMed Web of Science ®Google Scholar
• Inomata S, Matsunaga Y, Amano S, et al. Possible involvement of gelatinases in basement membrane damage and wrinkle formation in chronically ultraviolet B-exposed hairless mouse. J Invest Dermatol. 2003;120(1):128–134.
   PubMed Web of Science ®Google Scholar
• Varani J, Perone P, Fligiel SEG, et al. Inhibition of type I procollagen production in photodamage: correlation between presence of high molecular weight collagen fragments and reduced procollagen synthesis. J Invest Dermatol. 2002;119(1):122–129.
   PubMed Web of Science ®Google Scholar
• Quan T, Qin Z, Xia W, et al. Matrix-degrading metalloproteinases in photoaging. J Investig Dermatol Symp Proc. 2009;14(1):20–24.
   PubMedGoogle Scholar
• Hwang E, Lee D-G, Park SH, et al. Coriander leaf extract exerts antioxidant activity and protects against UVB-induced photoaging of skin by regulation of procollagen type I and MMP-1 expression. J Med Food. 2002;15(9):985–995.
   Google Scholar
• Jung SK, Lee KW, Kim HY, et al. Myricetin suppresses UVB-induced wrinkle formation and MMP-9 expression by inhibiting Raf. Biochem Pharmacol. 2010;79(10):1455–1461.
   PubMed Web of Science ®Google Scholar
• Sbardella D, Fasciglione GF, Gioia M, et al. Human matrix metalloproteinases: an ubiquitarian class of enzymes involved in several pathological processes. Mol Aspects Med. 2012;33(2):119–208. .
   PubMed Web of Science ®Google Scholar
• Hwang E, Park S-Y, Lee HJ, et al. Gallic acid regulates skin photoaging in UVB-exposed fibroblast and hairless mice. Phytother Res PTR. 2014;28(12):1778–1788.
   PubMed Web of Science ®Google Scholar
• Park HM, Hwang E, Lee KG, et al. Royal jelly protects against ultraviolet B-induced photoaging in human skin fibroblasts via enhancing collagen production. J Med Food. 2011;14(9):899–906.
   PubMed Web of Science ®Google Scholar
• Alge-Priglinger CS, Kreutzer T, Obholzer K, et al. Oxidative Stress-Mediated Induction of MMP-1 and MMP-3 in Human RPE Cells. Invest Ophthalmol Vis Sci. 2009;50(11):5495–5503.
   PubMed Web of Science ®Google Scholar
• Martinez RM, Pinho-Ribeiro FA, Steffen VS, et al. Naringenin inhibits UVB irradiation-induced inflammation and oxidative stress in the skin of hairless mice. J Nat Prod. 2015;78(7):1647–1655.
   PubMed Web of Science ®Google Scholar
• Lee M, Sorn S, Baek S, et al. Antioxidant and apoptotic effects of korean white ginseng extracted with the same ratio of protopanaxadiol and protopanaxatriol saponins in human hepatoma HepG2 cells. Ann N Y Acad Sci. 2009;1171(1):217–227.
   PubMedGoogle Scholar
• Kang CH, Rhie SJ, Kim YC. Antioxidant and skin anti-aging effects of marigold methanol extract. Toxicol Res. 2018;34(1):31–39.
   PubMed Web of Science ®Google Scholar
• Zhao P, Alam M, Lee S-H. Protection of UVB-induced photoaging by fuzhuan-brick tea aqueous extract via MAPKs/Nrf2-mediated down-regulation of MMP-1. Nutrients. 2018;11(1):60.
   Web of Science ®Google Scholar
• Nobile V, Michelotti a, Cestone E, et al. Skin photoprotective and antiageing effects of a combination of rosemary (Rosmarinus officinalis) and grapefruit (Citrus paradisi) polyphenols. Food Nutr Res. 2016;60(1):31871.
   PubMed Web of Science ®Google Scholar
• Skin photoprotective and antiageing effects of a combination of rosemary (Rosmarinus officinalis) and grapefruit (Citrus paradisi) polyphenols [Internet]. [cited 2020 Jul 7]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931025/.
   Google Scholar
• Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin [Internet]. [cited 2020 Jul 7]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223080/.
   Google Scholar
• Pérez-Sánchez a, Barrajón-Catalán E, Caturla N, et al. Protective effects of citrus and rosemary extracts on UV-induced damage in skin cell model and human volunteers. J Photochem Photobiol B. 2014;136:12–18.
   PubMed Web of Science ®Google Scholar
• Gęgotek a, Ambrożewicz E, Jastrząb a, et al. Rutin and ascorbic acid cooperation in antioxidant and antiapoptotic effect on human skin keratinocytes and fibroblasts exposed to UVA and UVB radiation. Arch Dermatol Res. 2019;311(3):203–219.
   PubMed Web of Science ®Google Scholar
• Sthijns MMJPE, Schiffers PM, Janssen GM, et al. Rutin protects against H 2 O 2 -triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in human umbilical vein endothelial cells exposed to oxidative stress. Biochim Biophys Acta BBA - Gen Subj. 2017;1861(5):1177–1189.
   PubMed Web of Science ®Google Scholar
• Abengózar-Vela a, Calonge M, Stern ME, et al. Quercetin and resveratrol decrease the inflammatory and oxidative responses in human ocular surface epithelial cells. Invest Opthalmol Vis Sci. 2015;56(4):2709.
   PubMed Web of Science ®Google Scholar