Alpha-lipoic acid ameliorates H₂O₂-induced human vein endothelial cells injury via suppression of inflammation and oxidative stress

References

• Ildikó K. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med. 2005;4:353.
   Google Scholar
• Madamanchi NR, Runge MS. Redox signaling in cardiovascular health and disease. Free Radic Biol Med. 2013 Aug;61:473–501.
   PubMed Web of Science ®Google Scholar
• Roquer J, Segura T, Serena J, et al. Endothelial dysfunction, vascular disease and stroke: the ARTICO study. Cerebrovasc Dis. 2009;27(Suppl 1):25–37.
   PubMed Web of Science ®Google Scholar
• D’Agnillo F, Wood F, Porras C, et al. Effects of hypoxia and glutathione depletion on hemoglobin- and myoglobin-mediated oxidative stress toward endothelium. Biochim Biophys Acta. 2000 Feb 2;1495(2):150–159.
   PubMed Web of Science ®Google Scholar
• Skibska B, Goraca A. The protective effect of lipoic acid on selected cardiovascular diseases caused by age-related oxidative stress. Oxid Med Cell Longev. 2015;2015:313021.
   PubMed Web of Science ®Google Scholar
• Lee YJ, Kang IJ, Bunger R, et al. Mechanisms of pyruvate inhibition of oxidant-induced apoptosis in human endothelial cells. Microvasc Res. 2003 Sep;66(2):91–101.
   PubMed Web of Science ®Google Scholar
• Drummond GR, Selemidis S, Griendling KK, et al. Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat Rev Drug Discov. 2011;10(6):453–471.
   PubMed Web of Science ®Google Scholar
• Armoza A, Haim Y, Bashiri A, et al. Tomato extract and the carotenoids lycopene and lutein improve endothelial function and attenuate inflammatory NF-κB signaling in endothelial cells. J Hypertens. 2013 Mar;31(3):521–529. discussion 529.
   PubMed Web of Science ®Google Scholar
• Warren MC, Bump EA, Medeiros D, et al. Oxidative stress-induced apoptosis of endothelial cells. Free Radic Biol Med. 2000;29(6):537–547.
   PubMed Web of Science ®Google Scholar
• Choi YJ, Kang JS, Park JH, et al. Polyphenolic flavonoids differ in their antiapoptotic efficacy in hydrogen peroxide-treated human vascular endothelial cells. J Nutr. 2003 Apr;133(4):985–991.
   PubMed Web of Science ®Google Scholar
• Fotis L, Agrogiannis G, Vlachos IS, et al. Intercellular adhesion molecule (ICAM)-1 and vascular cell adhesion molecule (VCAM)-1 at the early stages of atherosclerosis in a rat model. In Vivo. 2012 Mar-Apr;26(2):243–250.
   PubMed Web of Science ®Google Scholar
• Marzolla V, Armani A, Mammi C, et al. Essential role of ICAM-1 in aldosterone-induced atherosclerosis. Int J Cardiol. 2017 Apr 1;232:233–242.
   PubMed Web of Science ®Google Scholar
• Smith JD, Dansky HM, Breslow JL. Genetic modifiers of atherosclerosis in mice. Ann N Y Acad Sci. 2001 Dec;947:247–252. discussion 252-3.
   PubMed Web of Science ®Google Scholar
• Fu Y, Hu X, Cao Y, et al. Saikosaponin a inhibits lipopolysaccharide-oxidative stress and inflammation in Human umbilical vein endothelial cells via preventing TLR4 translocation into lipid rafts. Free Radic Biol Med. 2015;89:777–785.
   PubMed Web of Science ®Google Scholar
• Chen J, Gong F, Chen M-F, et al. In vitro vascular-protective effects of a tilapia by-product oligopeptide on angiotensin II-induced hypertensive endothelial injury in HUVEC by Nrf2/NF-κB pathways. Mar Drugs. 2019;17(7):431.
   Web of Science ®Google Scholar
• Ghibu S, Richard C, Vergely C, et al. Antioxidant properties of an endogenous thiol: alpha-lipoic acid, useful in the prevention of cardiovascular diseases. J Cardiovasc Pharmacol. 2009 Nov;54(5):391–398.
   PubMed Web of Science ®Google Scholar
• Ismawati, Mukhyarjon, Asni E, et al. The effect of alpha-lipoic acid on expression of VCAM-1 in type 2 diabetic rat. Anat Cell Biol. 2019 Jun;52(2):176–182.
   PubMed Web of Science ®Google Scholar
• Wollin PJHJ SD. Alpha-lipoic acid and cardiovascular disease. J Nutr. 2003;133(11):3327–3330.
   PubMed Web of Science ®Google Scholar
• Sungmi P. Physiological effect and therapeutic application of alpha lipoic acid. Curr Med Chem. 2014;32(21):3636–3645.
   Google Scholar
• Lee WJ, Lee IK, Kim HS, et al. Alpha-lipoic acid prevents endothelial dysfunction in obese rats via activation of AMP-activated protein kinase. Arterioscler Thromb Vasc Biol. 2005 Dec;25(12):2488–2494.
   PubMed Web of Science ®Google Scholar
• Jones W, Li X, Qu ZC, et al. Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells. Free Radic Biol Med. 2002 Jul 1;33(1):83–93.
   PubMed Web of Science ®Google Scholar
• Rochette L, Ghibu S, Richard C, et al. Direct and indirect antioxidant properties of alpha-lipoic acid and therapeutic potential. Mol Nutr Food Res. 2013 Jan;57(1):114–125.
   PubMed Web of Science ®Google Scholar
• Shen J, Zhu Y, Huang K, et al. Buyang Huanwu Decoction attenuates H2O2-induced apoptosis by inhibiting reactive oxygen species-mediated mitochondrial dysfunction pathway in human umbilical vein endothelial cells. BMC Complement Altern Med. 2016 May 31;16:154.
   PubMed Web of Science ®Google Scholar
• Kim EJ, Park WH, Ahn SG, et al. 5ʹ-nitro-indirubinoxime inhibits inflammatory response in TNF-alpha stimulated human umbilical vein endothelial cells. Atherosclerosis. 2010 Jul;211(1):77–83.
   PubMed Web of Science ®Google Scholar
• Tang X, Yang X, Peng Y, et al. Protective effects of lycopene against H2O2-induced oxidative injury and apoptosis in human endothelial cells. Cardiovasc Drugs Ther. 2009 Dec;23(6):439–448.
   PubMed Web of Science ®Google Scholar
• Hort MA, Straliotto MR, de Oliveira J, et al. Diphenyl diselenide protects endothelial cells against oxidized low density lipoprotein-induced injury: involvement of mitochondrial function. Biochimie. 2014;105:172–181.
   PubMed Web of Science ®Google Scholar
• Song L, Kang C, Sun Y, et al. Crocetin inhibits lipopolysaccharide-induced inflammatory response in human umbilical vein endothelial cells. Cell Physiol Biochem. 2016;40(3–4):443–452.
   PubMedGoogle Scholar
• Xu J, Zhou L, Weng Q, et al. Curcumin analogues attenuate Aβ25-35-induced oxidative stress in PC12 cells via Keap1/Nrf2/HO-1 signaling pathways. Chem Biol Interact. 2019;305:171–179.
   PubMed Web of Science ®Google Scholar
• Konior A, Schramm A, Czesnikiewicz-Guzik M, et al. NADPH oxidases in vascular pathology. Antioxid Redox Signal. 2014 Jun 10;20(17):2794–2814.
   PubMed Web of Science ®Google Scholar
• Jiawei Chen JLM. Role of oxidative stress in coronary heart disease. Indian Heart. 2004;56(02):163–173.
   PubMedGoogle Scholar
• Deng H, Chu X, Song Z, et al. MicroRNA-1185 Induces Endothelial Cell Apoptosis by Targeting UVRAG and KRIT1. Cell Physiol Biochem. 2017;41(6):2171–2182.
   PubMedGoogle Scholar
• Brenner C, Cadiou H, Vieira HLA, et al. Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator. Oncogene. 2000;19(3):329–336.
   PubMed Web of Science ®Google Scholar
• Renault TT, Manon S. Bax: addressed to kill. Biochimie. 2011 Sep;93(9):1379–1391.
   PubMed Web of Science ®Google Scholar
• Ferreira Cda S, Maganhin CC, Simoes Rdos S, et al. Melatonin: cell death modulator. Revista da Associacao Medica Brasileira (1992). 2010 Nov-Dec;56(6):715–718.
   PubMed Web of Science ®Google Scholar
• Choi WS, Jeong JW, Kim SO, et al. Anti-inflammatory potential of peat moss extracts in lipopolysaccharide-stimulated RAW 264.7 macrophages. Int J Mol Med. 2014 Oct;34(4):1101–1109.
   PubMed Web of Science ®Google Scholar
• Luo Y, Lu Y. 2ʹ,4ʹ-dihydroxy-6ʹ-methoxy-3ʹ,5ʹ-dimethylchalcone inhibits apoptosis of MIN6 cells via improving mitochondrial function. Pharmazie. 2012 Sep;67(9):798–803.
   PubMed Web of Science ®Google Scholar
• Fang WT, Li HJ, Zhou LS. Protective effects of prostaglandin E1 on human umbilical vein endothelial cell injury induced by hydrogen peroxide. Acta Pharmacol Sin. 2010 Apr;31(4):485–492.
   PubMed Web of Science ®Google Scholar
• Hao XL, Kang Y, Li JK, et al. Protective effects of hyperoside against H2O2-induced apoptosis in human umbilical vein endothelial cells. Mol Med Rep. 2016 Jul;14(1):399–405.
   PubMed Web of Science ®Google Scholar
• Zhang J, Deng H, Liu L, et al. Alpha-Lipoic acid protects against hypoxia/reoxygenation-induced injury in human umbilical vein endothelial cells through suppression of apoptosis and autophagy. Mol Med Rep. 2015 Jul;12(1):180–186.
   PubMed Web of Science ®Google Scholar
• Liu YX, Han GZ, Wu T, et al. Protective effect of alpha-lipoic acid on oxidized low density lipoprotein-induced human umbilical vein endothelial cell injury. Pharmacol Rep. 2011;63(5):1180–1188.
   PubMed Web of Science ®Google Scholar
• Petry A, Djordjevic T, Weitnauer M, et al. NOX2 and NOX4 mediate proliferative response in endothelial cells. Antioxid Redox Signal. 2006 Sep-Oct;8(9–10):1473–1484.
   PubMed Web of Science ®Google Scholar
• Surico D, Farruggio S, Marotta P, et al. Human chorionic gonadotropin protects vascular endothelial cells from oxidative stress by apoptosis inhibition, cell survival signalling activation and mitochondrial function protection. Cell Physiol Biochem. 2015;36(6):2108–2120.
   PubMedGoogle Scholar
• Youle RJ, Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol. 2008;9(1):47–59.
   PubMed Web of Science ®Google Scholar
• Onishi Y, Kawamoto T, Ueha T, et al. Transcutaneous application of carbon dioxide (CO2) induces mitochondrial apoptosis in human malignant fibrous histiocytoma in vivo. PloS One. 2012;7(11):e49189.
   PubMed Web of Science ®Google Scholar
• Antonsson B. Mitochondria and the Bcl-2 family proteins in apoptosis signaling pathways. Mol Cell Biochem. 2004;256-257(1–2):141–155.
   PubMed Web of Science ®Google Scholar
• McCabe C, Samali A, O’Brien T. beta cell cytoprotective strategies: establishing the relative roles for iNOS and ROS. Biochem Biophys Res Commun. 2006 Apr 21;342(4):1240–1248.
   PubMed Web of Science ®Google Scholar
• Baldwin AS Jr. Series introduction: the transcription factor NF-kappaB and human disease. J Clin Invest. 2001 Jan;107(1):3–6.
   PubMed Web of Science ®Google Scholar
• Balkis Budin S, Othman F, Louis SR, et al. Effect of alpha lipoic acid on oxidative stress and vascular wall of diabetic rats. Rom J Morphol Embryol. 2009;50(1):23–30.
   PubMed Web of Science ®Google Scholar