606
Views
0
CrossRef citations to date
0
Altmetric
Research Article

A combination of Polypodium leucotomos extract with vitamin A, vitamin C and selenium as an immune adjuvant against recurrent infections

, , , , , , & show all
Article: 2249261 | Received 25 May 2023, Accepted 14 Aug 2023, Published online: 14 Sep 2023

References

  • Aguzzi, C., Marinelli, O., Zeppa, L., Santoni, G., Maggi, F., & Nabissi, M. (2020). Evaluation of anti-inflammatory and immunoregulatory activities of Stimunex® and Stimunex D3® in human monocytes/macrophages stimulated with LPS or IL-4/IL-13. Biomedicine & Pharmacotherapy, 132, 110845. https://doi.org/10.1016/j.biopha.2020.110845
  • Al Aboody, M. S., & Mickymaray, S. (2020). Anti-fungal efficacy and mechanisms of flavonoids. Antibiotics, 9, 45. https://doi.org/10.3390/antibiotics9020045
  • Anderson, J., & Paterek, E. (2023, Aug 8). Tonsillitis. In StatPearls [Internet]. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK430685/
  • Ayala, G., Escobedo-Hinojosa, W. I., de la Cruz-Herrera, C. F., & Romero, I. (2014). Exploring alternative treatments for Helicobacter pylori infection. World Journal of Gastroenterology, 20(6), 1450–1469. https://doi.org/10.3748/wjg.v20.i6.1450
  • Baharfar, R., Azimi, R., & Mohseni, M. (2015). Antioxidant and antibacterial activity of flavonoid-, polyphenol- and anthocyanin-rich extracts from Thymus kotschyanus boiss & hohen aerial parts. Journal of Food Science and Technology, 52(10), 6777–6783. https://doi.org/10.1007/s13197-015-1752-0
  • Chiancone, F., Carrino, M., Meccariello, C., Pucci, L., Fedelini, M., & Fedelini, P. (2019). The use of a combination of Vaccinium macracarpon, Lycium barbarum L. and probiotics (Bifiprost®) for the prevention of chronic bacterial prostatitis: A double-blind randomized study. Urologia Internationalis, 103(4), 423–426. https://doi.org/10.1159/000502765
  • del Carmen Juárez-Vázquez, M., Josabad Alonso-Castro, A., & García-Carrancá, A. (2013). Kaempferitrin induces immunostimulatory effects in vitro. Journal of Ethnopharmacology, 148(1), 337–340. https://doi.org/10.1016/j.jep.2013.03.072
  • De Luca, C., Kharaeva, Z., Raskovic, D., Pastore, P., Luci, A., & Korkina, L. (2012). Coenzyme Q10, vitamin E, selenium, and methionine in the treatment of chronic recurrent viral mucocutaneous infections. Nutrition, 28, 509–514. https://doi.org/10.1016/j.nut.2011.08.003
  • El-Sayed, S. M., Hassan, K. M., Abdelhamid, A. N., Yousef, E. E., Abdellatif, Y. M., Abu-Hussien, S. H., Nasser, M. A., Elshalakany, W. A., Darwish, D. B. E., Abdulmajeed, A. M., & Alabdallah, N. M. (2022). Exogenous Paclobutrazol reinforces the antioxidant and antimicrobial properties of lavender (Lavandula officinalis L.) oil through modulating its composition of oxygenated terpenes. Plants, 11, 1607. https://doi.org/10.3390/plants11121607
  • Ferrara, P., Ianniello, F., Bianchi, V., Quintarelli, F., Cammerata, M., Quattrocchi, E., Terranova, G. M., Miggiano, G. A., & Casale, M. (2021). Beneficial therapeutic effects of vitamin C on recurrent respiratory tract infections in children: Preliminary data. Minerva Pediatrics, 73, 22–27. https://doi.org/10.23736/S2724-5276.16.04621-1
  • Ivanov, A. V., Bartosch, B., & Isaguliants, M. G. (2017). Oxidative stress in infection and consequent disease. Oxidative Medicine and Cellular Longevity, 2017, https://doi.org/10.1155/2017/3496043
  • Iyer, S. S., & Cheng, G. (2012). Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease. Critical Reviews™ in Immunology, 32(1), 23–63. https://doi.org/10.1615/CritRevImmunol.v32.i1.30
  • Jańczyk, A., Garcia-Lopez, M. A., Fernandez-Peñas, P., Alonso-Lebrero, J. L., Benedicto, I., López-Cabrera, M., & Gonzalez, S. (2007). A Polypodium leucotomos extract inhibits solar-simulated radiation-induced TNF-? and iNOS expression, transcriptional activation and apoptosis. Experimental Dermatology, 16(10), 823–829. https://doi.org/10.1111/j.1600-0625.2007.00603.x
  • Jeitler, M., Michalsen, A., Schwiertz, A., Kessler, C. S., Koppold-Liebscher, D., Grasme, J., Kandil, F. I., & Steckhan, N. (2022). Effects of a supplement containing a cranberry extract on recurrent urinary tract infections and intestinal microbiota: A prospective, uncontrolled exploratory study. Journal of Integrative and Complementary Medicine, 28, 399–406. https://doi.org/10.1089/jicm.2021.0300
  • Jiang, M. Z., Yan, H., Wen, Y., & Li, X. M. (2011). In vitro and in vivo studies of antioxidant activities of flavonoids from Adiantum capillus-veneris L. African Journal of Pharmacy and Pharmacology, 5, https://doi.org/10.5897/AJPP11.500
  • Koradia, P., Kapadia, S., Trivedi, Y., Chanchu, G., & Harper, A. (2019). Probiotic and cranberry supplementation for preventing recurrent uncomplicated urinary tract infections in premenopausal women: A controlled pilot study. Expert Review of Anti-Infective Therapy, 17(9), 733–740. https://doi.org/10.1080/14787210.2019.1664287
  • Kutwin, P., Falkowski, P., Łowicki, R., Borowiecka-Kutwin, M., & Konecki, T. (2022). Are we sentenced to pharmacotherapy? Promising role of lycopene and vitamin A in benign urologic conditions. Nutrients, 14, 859. https://doi.org/10.3390/nu14040859
  • Lee, S.-H., & Vidal, S. M. (2002). Functional diversity of Mx proteins: Variations on a theme of host resistance to infection. Genome Research, 12(4), 527–530. https://doi.org/10.1101/gr.20102
  • Middelkamp-Hup, M. A., Pathak, M. A., Parrado, C., Goukassian, D., Rius-Díaz, F., Mihm, M. C., Fitzpatrick, T. B., & González, S. (2004). Oral Polypodium leucotomos extract decreases ultraviolet-induced damage of human skin. Journal of the American Academy of Dermatology, 51(6), 910–918. https://doi.org/10.1016/j.jaad.2004.06.027
  • Murira, A., & Lamarre, A. (2016). Type-I interferon responses: From friend to foe in the battle against chronic viral infection. Frontiers in Immunology, 7.
  • Nadjib, B. M. (2020). Effective antiviral activity of essential oils and their characteristic terpenes against coronaviruses: An update. Journal of Pharmacology Clinical Toxicology, 9.
  • Nudo, L. P., & Catap, E. S. (2011). Immunostimulatory effects of Uncaria perrottetii (A. Rich.) Merr.(Rubiaceae) vinebark aqueous extract in Balb/C mice. Journal of Ethnopharmacology, 133(2), 613–620. https://doi.org/10.1016/j.jep.2010.10.044
  • Panigrahy, D., Gilligan, M. M., Serhan, C. N., & Kashfi, K. (2021). Resolution of inflammation: An organizing principle in biology and medicine. Pharmacology & Therapeutics, 227, 107879. https://doi.org/10.1016/j.pharmthera.2021.107879
  • Park, H.-Y., Yu, A.-R., Choi, I.-W., Hong, H.-D., Lee, K.-W., & Choi, H.-D. (2013). Immunostimulatory effects and characterization of a glycoprotein fraction from rice bran. International Immunopharmacology, 17(2), 191–197. https://doi.org/10.1016/j.intimp.2013.06.013
  • Piersma, S. J., & Brizić, I. (2022). Natural killer cell effector functions in antiviral defense. The FEBS Journal, 289(14), 3982–3999. https://doi.org/10.1111/febs.16073
  • Portillo-Esnaola, M., Rodríguez-Luna, A., Nicolás-Morala, J., Gallego-Rentero, M., Villalba, M., Juarranz, Á, & González, S. (2021). Formation of cyclobutane pyrimidine dimers after UVA exposure (Dark-CPDs) is inhibited by an hydrophilic extract of Polypodium leucotomos. Antioxidants, 10(12), 1961. https://doi.org/10.3390/antiox10121961
  • Rösler, D., Fuchs, N., Markolin, G., Edler, B., Kuklinski, B., & Kästenbauer, T. (2012). Reduction of influenza-like infections by a phytoextract-vitamin-combination: A randomized, double-blind, placebo-controlled study. MMW Fortschritte der Medizin, 154(Suppl 4), 115–122.
  • Sánchez-Rodríguez, C. (2018). Immunomodulatory effect of Polypodium leucotomos (Anapsos) in child palatine tonsil model. International Journal of Pediatric Otorhinolaryngology, 6.
  • Saxena, A., Khosraviani, S., Noel, S., Mohan, D., Donner, T., & Hamad, A. R. A. (2015). Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy. Cytokine, 74(1), 27–34. https://doi.org/10.1016/j.cyto.2014.10.031
  • Schink, A., Neumann, J., Leifke, A. L., Ziegler, K., Fröhlich-Nowoisky, J., Cremer, C., Thines, E., Weber, B., Pöschl, U., Schuppan, D., & Lucas, K. (2018). Screening of herbal extracts for TLR2-and TLR4-dependent anti-inflammatory effects. PloS one, 13, e0203907. https://doi.org/10.1371/journal.pone.0203907
  • Segars, K., McCarver, V., & Miller, R. A. (2021). Dermatologic applications of Polypodium leucotomos: A literature review. The Journal of Clinical and Aesthetic Dermatology, 14, 50–60.
  • Sempere, J. M., Rodrigo, C., Campos, A., Villalba, J. F., & Diaz, J. (1997). Effect of anapsos (Polypodium leucotomos extract) on in vitro production of cytokines. British Journal of Clinical Pharmacology, 43(1), 85–89. https://doi.org/10.1111/j.1365-2125.1997.tb00142.x
  • Sempere-Ortells, J. M., Campos, A., Velasco, I., Marco, F., Ramirez-bosca, A., Diaz, J., & Pardo, J. (2002). Anapsos (Polypodium leucotomos) modulates lymphoid cells and the expression of adhesion molecules. Pharmacological Research, 46(2), 185–190. https://doi.org/10.1016/S1043-6618(02)00091-9
  • Serhan, C. N. (2017). Treating inflammation and infection in the 21st century: New hints from decoding resolution mediators and mechanisms. The FASEB Journal, 31(4), 1273–1288. https://doi.org/10.1096/fj.201601222R
  • Sharma, P., Kaur, J., Sharma, G., & Kashyap, P. (2022). Plant derived antimicrobial peptides: Mechanism of target, isolation techniques, sources and pharmaceutical applications. Journal of Food Biochemistry, 46, https://doi.org/10.1111/jfbc.14348
  • Solivellas, B. M., & Martín, T. C. (2012). Polypodium leucotomos extract use to prevent and reduce the risk of infectious diseases in high performance athletes. Infection and Drug Resistance, 5, 149–153. https://doi.org/10.2147/IDR.S29113
  • Sun, X., Cameron, R. G., & Bai, J. (2020). Effect of spray-drying temperature on physicochemical, antioxidant and antimicrobial properties of pectin/sodium alginate microencapsulated carvacrol. Food Hydrocolloids, 100, 105420. https://doi.org/10.1016/j.foodhyd.2019.105420
  • Vellingiri, B., Jayaramayya, K., Iyer, M., Narayanasamy, A., Govindasamy, V., Giridharan, B., Ganesan, S., Venugopal, A., Venkatesan, D., Ganesan, H., & Rajagopalan, K. (2020). COVID-19: A promising cure for the global panic. Science of The Total Environment, 725, 138277. https://doi.org/10.1016/j.scitotenv.2020.138277
  • Wang, L., Song, J., Liu, A., Xiao, B., Li, S., Wen, Z., Lu, Y., & Du, G. (2020). Research progress of the antiviral bioactivities of natural flavonoids. Natural Products and Bioprospecting, 10, 271–283. https://doi.org/10.1007/s13659-020-00257-x
  • Wimalawansa, S. J. (2022). Rapidly increasing serum 25(OH)D boosts the immune system, against infections – sepsis and COVID-19. Nutrients, 14(14), 2997. https://doi.org/10.3390/nu14142997
  • Xiao, J., & He, W. (2021). The immunomodulatory effects of vitamin D drops in children with recurrent respiratory tract infections. American Journal of Translational Research, 13, 1750–1756.
  • Yin, L., Han, H., Zheng, X., Wang, G., Li, Y., & Wang, W. (2019). Flavonoids analysis and antioxidant, antimicrobial, and anti-inflammatory activities of crude and purified extracts from Veronicastrum latifolium. Industrial Crops and Products, 137, 652–661. https://doi.org/10.1016/j.indcrop.2019.04.007
  • Zattra, E., Coleman, C., Arad, S., Helms, E., Levine, D., Bord, E., Guillaume, A., El-Hajahmad, M., Zwart, E., van Steeg, H., Gonzalez, S., Kishore, R., & Goukassian, D. A. (2009). Polypodium leucotomos extract decreases UV-induced Cox-2 expression and inflammation, enhances DNA repair, and decreases mutagenesis in hairless mice. The American Journal of Pathology, 175(5), 1952–1961. https://doi.org/10.2353/ajpath.2009.090351
  • Zhu, F., Du, B., & Xu, B. (2018). Anti-Inflammatory effects of phytochemicals from fruits, vegetables, and food legumes: A review. Critical Reviews in Food Science and Nutrition, 58(8), 1260–1270. https://doi.org/10.1080/10408398.2016.1251390