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Articles

Effects of 5.8 GHz microwave on hippocampal synaptic plasticity of rats

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Pages 2247-2259 | Received 04 Dec 2020, Accepted 02 Jul 2021, Published online: 22 Jul 2021

References

  • Aitken RJ, Bennetts LE, Sawyer D, Wiklendt AM, King BV. 2005. Impact of radio frequency electromagnetic radiation on DNA integrity in the male germline. Int J Androl. 28(3):171–179. doi:10.1111/j.1365-2605.2005.00531.x.
  • Bas O, Odaci E, Kaplan S, Acer N, Ucok K, Colakoglu S. 2009. 900 MHz electromagnetic field exposure affects qualitative and quantitative features of hippocampal pyramidal cells in the adult female rat. Brain Res. 1265:178–185. doi:10.1016/j.brainres.2009.02.011.
  • Becher A, Drenckhahn A, Pahner I, Margittai M, Jahn R, Ahnert-Hilger G. 1999. The synaptophysin-synaptobrevin complex: a hallmark of synaptic vesicle maturation. J Neurosci. 19(6):1922–1931. doi:10.1523/JNEUROSCI.19-06-01922.1999.
  • Carrasco C, RodrÍGuez AB, Pariente JA. 2015. Melatonin as a stabilizer of mitochondrial function: role in diseases and aging. Turk J Biol. 39(6):822–831. doi:10.3906/biy-1504-26.
  • Dawson TM, Ginty DD. 2002. CREB family transcription factors inhibit neuronal suicide. Nat Med. 8(5):450–451. doi:10.1038/nm0502-450.
  • El-Husseini AE, Schnell E, Chetkovich DM, Nicoll RA, Bredt DS. 2000. PSD-95 involvement in maturation of excitatory synapses. Science. 290(5495):1364–1368.
  • Ertilav K, Uslusoy F, Ataizi S, Naziroglu M. 2018. Long term exposure to cell phone frequencies (900 and 1800 MHz) induces apoptosis, mitochondrial oxidative stress and TRPV1 channel activation in the hippocampus and dorsal root ganglion of rats. Metab Brain Dis. 33(3):753–763. doi:10.1007/s11011-017-0180-4.
  • Fu ZX, Tan X, Fang H, Lau PM, Wang X, Cheng H, Bi GQ. 2017. Dendritic mitoflash as a putative signal for stabilizing long-term synaptic plasticity. Nat Commun. 8(1):31. doi:10.1038/s41467-017-00043-3.
  • Gokcek-Sarac C, Er H, Kencebay Manas C, Kantar Gok D, Ozen S, Derin N. 2017. Effects of acute and chronic exposure to both 900 MHz and 2100 MHz electromagnetic radiation on glutamate receptor signaling pathway. Int J Radiat Biol. 93(9):980–989.
  • Hao YH, Zhao L, Peng RY. 2015. Effects of microwave radiation on brain energy metabolism and related mechanisms. Mil Med Res. 2:4.
  • IEEE. Std C95.1TM-. 2005. IEEE Standard for Safety Levels with Respect to Human Exposure to Radio Frequency Electromagnetic Fields, 3 kHz to 300 GHz.
  • IEEE. Std C95.1TM-. 2019. IEEE Standard for Safety Levels with Respect to Human Exposure to Electric, Magnetic, and Electromagnetic Fields, 0 Hz to 300 GHz.
  • Jeong YJ, Son Y, Han NK, Choi HD, Pack JK, Kim N, Lee YS, Lee HJ. 2018. Impact of long-term RF-EMF on oxidative stress and neuroinflammation in aging brains of C57BL/6 mice. Int J Mol Sci. 19(7):2103. doi:10.3390/ijms19072103.
  • Kandel ER. 2001. The molecular biology of memory storage: a dialogue between genes and synapses. Science. 294(5544):1030–1038. doi:10.1126/science.1067020.
  • Khacho M, Harris R, Slack RS. 2019. Mitochondria as central regulators of neural stem cell fate and cognitive function. Nat Rev Neurosci. 20(1):34–48.
  • Kim JH, Sohn UD, Kim HG, Kim HR. 2018. Exposure to 835 MHz RF-EMF decreases the expression of calcium channels, inhibits apoptosis, but induces autophagy in the mouse hippocampus. Korean J Physiol Pharmacol. 22(3):277–289. doi:10.4196/kjpp.2018.22.3.277.
  • Kuzniar A, Laffeber C, Eppink B, Bezstarosti K, Dekkers D, Woelders H, Zwamborn AP, Demmers J, Lebbink JH, Kanaar R. 2017. Semi-quantitative proteomics of mammalian cells upon short-term exposure to non-ionizing electromagnetic fields. PLoS One. 12(2):e0170762. doi:10.1371/journal.pone.0170762.
  • Luo Y, Kuang S, Li H, Ran D, Yang J. 2017. cAMP/PKA-CREB-BDNF signaling pathway in hippocampus mediates cyclooxygenase 2-induced learning/memory deficits of rats subjected to chronic unpredictable mild stress. Oncotarget. 8(22):35558–35572. doi:10.18632/oncotarget.16009.
  • Mamiya N, Fukushima H, Suzuki A, Matsuyama Z, Homma S, Frankland PW, Kida S. 2009. Brain region-specific gene expression activation required for reconsolidation and extinction of contextual fear memory. J Neurosci. 29(2):402–413. doi:10.1523/JNEUROSCI.4639-08.2009.
  • Middei S, Houeland G, Cavallucci V, Ammassari-Teule M, D’Amelio M, Marie H. 2013. CREB is necessary for synaptic maintenance and learning-induced changes of the ampa receptor GluA1 subunit. Hippocampus. 23(6):488–499. doi:10.1002/hipo.22108.
  • Miyakoshi J, Tonomura H, Koyama S, Narita E, Shinohara N. 2019. Effects of exposure to 5.8 GHz electromagnetic field on micronucleus formation, DNA strand breaks, and heat shock protein expressions in cells derived from human eye. IEEE Trans Nanobiosci. 18(2):257–260. doi:10.1109/TNB.2019.2905491.
  • Mortazavi SM, Taeb S, Dehghan N. 2013. Alterations of visual reaction time and short term memory in military radar personnel. Iran J Public Health. 42(4):428–435.
  • Narayanan SN, Kumar RS, Potu BK, Nayak S, Bhat GP, Mailankot M. 2010. Effect of radio-frequency electromagnetic radiations (RF-EMR) on passive avoidance behaviour and hippocampal morphology in Wistar rats. Ups J Med Sci. 115(2):91–96. doi:10.3109/03009730903552661.
  • Narayanan SN, Kumar RS, Potu BK, Nayak S, Mailankot M. 2009. Spatial memory performance of Wistar rats exposed to mobile phone. Clinics (Sao Paulo). 64(3):231–234. doi:10.1590/S1807-59322009000300014.
  • Naziroglu M, Yuksel M, Kose SA, Ozkaya MO. 2013. Recent reports of Wi-Fi and mobile phone-induced radiation on oxidative stress and reproductive signaling pathways in females and males. J Membr Biol. 246(12):869–875. doi:10.1007/s00232-013-9597-9.
  • Pakhomov AG, Doyle J, Stuck BE, Murphy MR. 2003. Effects of high power microwave pulses on synaptic transmission and long term potentiation in hippocampus. Bioelectromagnetics. 24(3):174–181. doi:10.1002/bem.10079.
  • Pittenger C, Duman RS. 2008. Stress, depression, and neuroplasticity: a convergence of mechanisms. Neuropsychopharmacol. 33(1):88–109.
  • Schoeni A, Roser K, Roosli M. 2015. Memory performance, wireless communication and exposure to radiofrequency electromagnetic fields: a prospective cohort study in adolescents. Environ Int. 85:343–351. doi:10.1016/j.envint.2015.09.025.
  • Shahin S, Banerjee S, Swarup V, Singh SP, Chaturvedi CM. 2018. From the cover: 2.45-GHz Microwave radiation impairs hippocampal learning and spatial memory: involvement of local stress mechanism-induced suppression of iGluR/ERK/CREB signaling. Toxicol Sci. 161(2):349–374. doi:10.1093/toxsci/kfx221.
  • Sharaf NE, Galal AF, El-Sawy MS, Shalby AB, Sayed AH, Ahmed HH. 2019. Role of designed Bio-Geometrical forms in antagonizing neurobehavioral burden of Wi-Fi radiation: evidence-based experimental study. Biomed Pharmacol J. 12(3):1217–1234. doi:10.13005/bpj/1751.
  • Shirai T, Wang J, Kawabe M, Wake K, Watanabe SI, Takahashi S, Fujiwara O. 2017. No adverse effects detected for simultaneous whole-body exposure to multiple-frequency radiofrequency electromagnetic fields for rats in the intrauterine and pre- and post-weaning periods. J Radiat Res. 58(1):48–58. doi:10.1093/jrr/rrw085.
  • Silva AJ, Kogan JH, Frankland PW, Kida S. 1998. CREB and Memory. Annu Rev Neurosci. 21(1):127–148. doi:10.1146/annurev.neuro.21.1.127.
  • Son Y, Jeong YJ, Kwon JH, Choi HD, Pack JK, Kim N, Lee YS, Lee HJ. 2016. 1950 MHz radiofrequency electromagnetic fields do not aggravate memory deficits in 5xFAD mice. Bioelectromagnetics. 37(6):391–399. doi:10.1002/bem.21992.
  • Tan S, Wang H, Xu X, Zhao L, Zhang J, Dong J, Yao B, Wang H, Zhou H, Gao Y, et al. 2017. Study on dose-dependent, frequency-dependent, and accumulative effects of 1.5 GHz and 2.856 GHz microwave on cognitive functions in Wistar rats. Sci Rep. 7(1):10781. doi:10.1038/s41598-017-11420-9
  • Van Deventer E, van Rongen E, Saunders R. 2011. WHO research agenda for radiofrequency fields. Bioelectromagnetics. 32(5):417–421. doi:10.1002/bem.20660.
  • Varghese R, Majumdar A, Kumar G, Shukla A. 2018. Rats exposed to 2.45GHz of non-ionizing radiation exhibit behavioral changes with increased brain expression of apoptotic caspase 3. Pathophysiology. 25(1):19–30. doi:10.1016/j.pathophys.2017.11.001.
  • Vorhees CV, Williams MTJNP. 2006. Morris water maze: procedures for assessing spatial and related forms of learning and memory. Nat Protoc. 1(2):848–858. doi:10.1038/nprot.2006.116.
  • Wang L, Peng R, Hu X, Gao Y, Wang S, Zhao L, Dong J, Su Z, Xu X, Gao R, et al. 2009. Abnormality of synaptic vesicular associated proteins in cerebral cortex and hippocampus after microwave exposure. Synapse. 63(11):1010–1016. doi:10.1002/syn.20684
  • Wang L-F, Wei L, Qiao S-M, Gao X-N, Gao Y-B, Wang S-M, Zhao L, Dong J, Xu X-P, Zhou H-M, et al. 2015. Microwave-induced structural and functional injury of hippocampal and PC12 cells is accompanied by abnormal changes in the NMDAR-PSD95-CaMKII pathway. Pathobiology. 82(5):181–194. doi:10.1159/000398803
  • Xiong L, Sun CF, Zhang J, Gao YB, Wang LF, Zuo HY, Wang SM, Zhou HM, Xu XP, Dong J, et al. 2015. Microwave exposure impairs synaptic plasticity in the rat hippocampus and PC12 cells through over-activation of the NMDA receptor signaling pathway. Biomed Environ Sci. 28(1):13–24.
  • Xu S, Ning W, Xu Z, Zhou S, Chiang H, Luo J. 2006. Chronic exposure to GSM 1800-MHz microwaves reduces excitatory synaptic activity in cultured hippocampal neurons. Neurosci Lett. 398(3):253–257. doi:10.1016/j.neulet.2006.01.004.
  • Zhi W-J, Peng R-Y, Li H-J, Zou Y, Yao B-W, Wang C-Z, Liu Z-H, Gao X-H, Xu X-P, Dong J, et al. 2018. Microwave radiation leading to shrinkage of dendritic spines in hippocampal neurons mediated by SNK-SPAR pathway. Brain Res. 1679:134–143. doi:10.1016/j.brainres.2017.11.020.