A novel dendritic mesoporous silica based sustained hydrogen sulfide donor for the alleviation of adjuvant-induced inflammation in rats

References

• Alaaeldin E, Abou-Taleb HA, Mohamad SA, et al. (2021). Topical nano-vesicular spanlastics of celecoxib: enhanced anti-inflammatory effect and down-regulation of TNF-α, NF-кB and COX-2 in complete Freund’s adjuvant-induced arthritis model in rats. IJN 16:133–45.
   Web of Science ®Google Scholar
• Assouvie A, Daley-Bauer LP, Rousselet G. (2018). Growing murine bone marrow-derived macrophages. Methods Mol Biol 784:29–33.
   Google Scholar
• Balas F, Manzano M, Horcajada P, Vallet-Regí M. (2006). Confinement and controlled release of bisphosphonates on ordered mesoporous silica-based materials. J Am Chem Soc 128:8116–7.
   PubMed Web of Science ®Google Scholar
• Bełtowski J, Jamroz-Wis¨niewska A. (2014). Hydrogen sulfide and endothelium-dependent vasorelaxation. Molecules 19:21183–99.
   PubMed Web of Science ®Google Scholar
• Bossaller L, Rothe A. (2013). Monoclonal antibody treatments for rheumatoid arthritis. Expert Opin Biol Ther 13:1257–72.
   PubMed Web of Science ®Google Scholar
• Braz WR, Rocha NL, De Faria EH, et al. (2016). Incorporation of anti-inflammatory agent into mesoporous silica. Nanotechnology 27:385103.
   PubMed Web of Science ®Google Scholar
• Burguera EF, Meijide-Failde R, Blanco FJ. (2017). Hydrogen sulfide and inflammatory joint diseases. CDT 18:1641–52.
   Web of Science ®Google Scholar
• Chan ESL, Fernandez P, Cronstein BN. (2007). Methotrexate in rheumatoid arthritis. Expert Rev Clin Immunol 3:27–33.
   PubMedGoogle Scholar
• Chen CH, Kuo SM, Tien YC, et al. (2020). Steady augmentation of anti-osteoarthritic actions of rapamycin by liposome-encapsulation in collaboration with low-intensity pulsed ultrasound. IJN 15:3771–90.
   Web of Science ®Google Scholar
• Chen CQ, Xin H, Zhu YZ. (2007). Hydrogen sulfide: third gaseous transmitter, but with great pharmacological potential. Acta Pharmacol Sin 28:1709–16.
   PubMed Web of Science ®Google Scholar
• Chuang CH, Cheng YC, Lin SC, et al. (2019). Atractylodin suppresses dendritic cell maturation and ameliorates collagen-induced arthritis in a mouse model. J Agric Food Chem 67:6773–84.
   PubMed Web of Science ®Google Scholar
• Davignon JL, Hayder M, Baron M, et al. (2013). Targeting monocytes/macrophages in the treatment of rheumatoid arthritis. Rheumatology (United Kingdom) 52:590–8.
   PubMed Web of Science ®Google Scholar
• Davoli A, Greco V, Spalloni A, et al. (2015). Evidence of hydrogen sulfide involvement in amyotrophic lateral sclerosis. Ann Neurol 77:697–709.
   PubMed Web of Science ®Google Scholar
• Desai D, Prabhakar N, Mamaeva V, et al. (2016). Targeted modulation of cell differentiation in distinct regions of the gastrointestinal tract via oral administration of differently PEG-PEI functionalized mesoporous silica nanoparticles. Int J Nanomed 11:299–313.
   PubMed Web of Science ®Google Scholar
• Eto K, Asada T, Arima K, et al. (2002). Brain hydrogen sulfide is severely decreased in Alzheimer’s disease. Biochem Biophys Res Commun 293:1485–8.
   PubMed Web of Science ®Google Scholar
• Ferreira JF, Ahmed Mohamed AA, Emery P. (2016). Glucocorticoids and rheumatoid arthritis. Rheum Dis Clin North Am 42:33–46.
   PubMed Web of Science ®Google Scholar
• Gong QH, Wang Q, Pan LL, et al. (2011). S-Propargyl-cysteine, a novel hydrogen sulfide-modulated agent, attenuates lipopolysaccharide-induced spatial learning and memory impairment: Involvement of TNF signaling and NF-κB pathway in rats. Brain Behav Immun 25:110–9.
   PubMed Web of Science ®Google Scholar
• van Grieken R, Escola JM, Moreno J, Rodríguez R. (2009). Direct synthesis of mesoporous M-SBA-15 (M = Al, Fe, B, Cr) and application to 1-hexene oligomerization. Chem Eng J 155:442–50.
   Web of Science ®Google Scholar
• Hu LF, Lu M, Tiong CX, et al. (2010). Neuroprotective effects of hydrogen sulfide on Parkinson’s disease rat models. Aging Cell 9:135–46.
   PubMed Web of Science ®Google Scholar
• Huang C, Kan J, Liu X, et al. (2013). Cardioprotective effects of a novel hydrogen sulfide agent-controlled release formulation of S-propargyl-cysteine on heart failure rats and molecular mechanisms. PLoS ONE 8:e69205.
   PubMed Web of Science ®Google Scholar
• Huang CC, Huang W, Yeh CS. (2011). Shell-by-shell synthesis of multi-shelled mesoporous silica nanospheres for optical imaging and drug delivery. Biomaterials 32:556–64.
   PubMed Web of Science ®Google Scholar
• Huang X, Li L, Liu T, et al. (2011). The shape effect of mesoporous silica nanoparticles on biodistribution, clearance, and biocompatibility in vivo. ACS Nano 5:5390–9.
   PubMed Web of Science ®Google Scholar
• Ishibashi T. (2013). Molecular hydrogen: new antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases. CPD 19:6375–81.
   Google Scholar
• Katsouda A, Bibli SI, Pyriochou A, et al. (2016). Regulation and role of endogenously produced hydrogen sulfide in angiogenesis. Pharmacol Res 113:175–85.
   PubMed Web of Science ®Google Scholar
• Kinne RW, Stuhlmüller B, Burmester GR. (2007). Cells of the synovium in rheumatoid arthritis. Macrophages. Arthritis Res Ther 9:224.
   PubMed Web of Science ®Google Scholar
• Kumari A, Yadav SK, Yadav SC. (2010). Biodegradable polymeric nanoparticles based drug delivery systems. Colloids Surf B Biointerfaces 75:1–18.
   PubMed Web of Science ®Google Scholar
• Lee EB, Fleischmann R, Hall S, et al. (2014). Tofacitinib versus methotrexate in rheumatoid arthritis. N Engl J Med 370:2377–86.
   PubMed Web of Science ®Google Scholar
• Lee S, Yun HS, Kim SH. (2011). The comparative effects of mesoporous silica nanoparticles and colloidal silica on inflammation and apoptosis. Biomaterials 32:9434–43.
   PubMed Web of Science ®Google Scholar
• Lee ZW, Zhou J, Chen CS, et al. (2011). The slow-releasing Hydrogen Sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitro and in vivo. PLoS ONE 6:e21077.
   PubMed Web of Science ®Google Scholar
• Li L, Liu T, Fu C, et al. (2015). Biodistribution, excretion, and toxicity of mesoporous silica nanoparticles after oral administration depend on their shape. Nanomedicine 11:1915–24.
   PubMed Web of Science ®Google Scholar
• Liang YH, Shen YQ, Guo W, Zhu YZ. (2014). SPRC protects hypoxia and re-oxygenation injury by improving rat cardiac contractile function and Intracellular calcium handling. Nitric Oxide 41:113–9.
   PubMed Web of Science ®Google Scholar
• Liu Y, Huang B, Zhu J, et al. (2018). Dual-generation dendritic mesoporous silica nanoparticles for co-delivery and kinetically sequential drug release. RSC Adv 8:40598–610.
   PubMed Web of Science ®Google Scholar
• Lopez-Olivo MA, Siddhanamatha HR, Shea B, et al. (2014). Methotrexate for treating rheumatoid arthritis. Cochrane Database Syst Rev 2014:CD000957.
   PubMedGoogle Scholar
• Lougiakis N, Papapetropoulos A, Gikas E, et al. (2016). Synthesis and pharmacological evaluation of novel adenine-hydrogen sulfide slow release hybrids designed as multitarget cardioprotective agents. J Med Chem 59:1776–90.
   PubMed Web of Science ®Google Scholar
• Low PS, Henne WA, Doorneweerd DD. (2008). Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases. Acc Chem Res 41:120–9.
   PubMed Web of Science ®Google Scholar
• Lu M, Liu YH, Goh HS, et al. (2010). Hydrogen sulfide inhibits plasma renin activity. J Am Soc Nephrol 21:993–1002.
   PubMed Web of Science ®Google Scholar
• Luo Z, Cai K, Hu Y, et al. (2011). Mesoporous silica nanoparticles end-capped with collagen: Redox-responsive nanoreservoirs for targeted drug delivery. Angew Chem 123:666–9.
   Google Scholar
• Ma G, Zhang L, Zhang P, et al. (2015). Physicochemical characteristics and gastrointestinal absorption behaviors of S-propargyl-cysteine, a potential new drug candidate for cardiovascular protection and antitumor treatment. Xenobiotica 45:322–34.
   PubMed Web of Science ®Google Scholar
• MA K, Liu Y, Zhu Q, et al. (2011). H2S donor, S-propargyl-cysteine, increases CSE in SGC-7901 and cancer-induced mice: evidence for a novel anti-cancer effect of endogenous H2S? PLoS ONE 6:e20525.
   PubMed Web of Science ®Google Scholar
• Ma Z, Tao C, Sun L, et al. (2019). In situ forming injectable hydrogel for encapsulation of nanoiguratimod and sustained release of therapeutics. IJN 14:8725–38.
   Web of Science ®Google Scholar
• Mccarthy CA, Ahern RJ, Dontireddy R, et al. (2016). Mesoporous silica formulation strategies for drug dissolution enhancement: a review. Expert Opin Drug Deliv 13:93–108.
   PubMed Web of Science ®Google Scholar
• McInnes IB, Schett G. (2011). The pathogenesis of rheumatoid arthritis. N Engl J Med 365:2205–19.
   PubMed Web of Science ®Google Scholar
• Mieszawska AJ, Mulder WJM, Fayad ZA, Cormode DP. (2013). Multifunctional gold nanoparticles for diagnosis and therapy of disease. Mol Pharm 10:831–47.
   PubMed Web of Science ®Google Scholar
• Mustafa AK, Sikka G, Gazi SK, et al. (2011). Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels. Circ Res 109:1259–68.
   PubMed Web of Science ®Google Scholar
• Pan LL, Liu XH, Gong QH, Zhu YZ. (2011). S-Propargyl-cysteine (SPRC) attenuated lipopolysaccharideinduced inflammatory response in H9c2 cells involved in a hydrogen sulfide-dependent mechanism. Amino Acids 41:205–15.
   PubMed Web of Science ®Google Scholar
• Papapetropoulos A, Pyriochou A, Altaany Z, et al. (2009). Hydrogen sulfide is an endogenous stimulator of angiogenesis. Proc Natl Acad Sci U S A 106:21972–7.
   PubMed Web of Science ®Google Scholar
• Ray A, Kumar D, Shakya A, et al. (2004). Serum amyloid A-activating factor-1 (SAF-1) transgenic mice are prone to develop a severe form of inflammation-induced arthritis. J Immunol 173:4684–91.
   PubMed Web of Science ®Google Scholar
• Rutherford A, Nikiphorou E, Galloway J. (2017). Rheumatoid arthritis. In: Comorbidity in rheumatic diseases. Cham: Springer, 53–79.
   Google Scholar
• Saeedi A, Najibi A, Mohammadi-Bardbori A. (2015). Effects of long-term exposure to hydrogen sulfide on human red blood cells. Int J Occup Environ Med 6: 20–5.
   PubMed Web of Science ®Google Scholar
• Sahni JK, Doggui S, Ali J, et al. (2011). Neurotherapeutic applications of nanoparticles in Alzheimer’s disease. J Controlled Release 152: 208–31.
   PubMed Web of Science ®Google Scholar
• Shen D, Yang J, Li X, et al. (2014). Biphase stratification approach to three-dimensional dendritic biodegradable mesoporous silica nanospheres. Nano Lett 14: 923–32.
   PubMed Web of Science ®Google Scholar
• Shen X, Chakraborty S, Dugas TR, Kevil CG. (2014). Hydrogen sulfide measurement using sulfide dibimane: Critical evaluation with electrospray ion trap mass spectrometry. Nitric Oxide 41:97–104.
   PubMed Web of Science ®Google Scholar
• Shen X, Pattillo CB, Pardue S, et al. (2011). Measurement of plasma hydrogen sulfide in vivo and in vitro. Free Radic Biol Med 50: 1021–31.
   PubMed Web of Science ®Google Scholar
• Shin HJ, Park H, Shin N, et al. (2020). p66shc siRNA nanoparticles ameliorate chondrocytic mitochondrial dysfunction in osteoarthritis. IJN Volume 15:2379–90.
   Web of Science ®Google Scholar
• Sidhapuriwala JN, Hegde A, Ang AD, et al. (2012). Effects of s-propargyl-cysteine (sprc) in caerulein-induced acute pancreatitis in mice. PLoS ONE 7:e32574.
   PubMed Web of Science ®Google Scholar
• Smolen JS, Steiner G. (2003). Therapeutic strategies for rheumatoid arthritis. Nat Rev Drug Discov 2: 473–88.
   PubMed Web of Science ®Google Scholar
• Stamp LK, Cleland LG. 2007. Rheumatoid arthritis. Optimizing Women’s Health through Nutrition.
   Google Scholar
• Streng T, Axelsson HE, Hedlund P, et al. (2008). Distribution and Function of the Hydrogen Sulfide-Sensitive TRPA1 Ion Channel in Rat Urinary Bladder. Eur Urol 53: 391–400.
   PubMed Web of Science ®Google Scholar
• Szekanecz Z, Koch AE. (2007). Macrophages and their products in rheumatoid arthritis. Current Opinion in Rheumatology 19:289–95.
   PubMed Web of Science ®Google Scholar
• Tamizhselvi R, Koh YH, Sun J, et al. (2010). Hydrogen sulfide induces ICAM-1 expression and neutrophil adhesion to caerulein-treated pancreatic acinar cells through NF-κB and Src-family kinases pathway. Exp Cell Res 316: 1625–36.
   PubMed Web of Science ®Google Scholar
• Thomas TP, Goonewardena SN, Majoros IJ, et al. (2011). Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis. Arthritis Rheum 63: 2671–80.
   PubMed Web of Science ®Google Scholar
• Tran BH, Huang C, Zhang Q, et al. (2015). Cardioprotective effects and pharmacokinetic properties of a controlled release formulation of a novel hydrogen sulfide donor in rats with acute myocardial infarction. Bioscience Reports 35: 1–12.
   Web of Science ®Google Scholar
• Tran BH, Yu Y, Chang L, et al. (2019a). A novel liposomal S-propargyl-cysteine: a sustained release of hydrogen sulfide reducing myocardial fibrosis via TGF-β1/smad pathway. Int J Nanomed 14:10061–77.
   PubMed Web of Science ®Google Scholar
• Tran BH, Yu Y, Chang L, et al. (2019b). A novel liposomal S-propargyl-cysteine: A sustained release of hydrogen sulfide reducing myocardial fibrosis via TGF-β1/smad pathway. IJN Volume 14:10061–77.
   Web of Science ®Google Scholar
• Udalova IA, Mantovani A, Feldmann M. (2016). Macrophage heterogeneity in the context of rheumatoid arthritis. Nat Rev Rheumatol 12: 472–85.
   PubMed Web of Science ®Google Scholar
• Wang M, Xin H, Tang W, et al. 2017. AMPK Serves as a Therapeutic Target Against Anemia of Inflammation. Antioxidants and Redox Signaling.
   Google Scholar
• Wang Q, Liu HR, Mu Q, et al. (2009). S-propargyl-cysteine protects both adult rat hearts and neonatal cardiomyocytes from ischemia/hypoxia injury: The contribution of the hydrogen sulfide-mediated pathway. Journal of Cardiovascular Pharmacology 54: 139–46.
   PubMed Web of Science ®Google Scholar
• Wang Q, Wang XL, Liu HR, et al. (2010). Protective effects of cysteine analogues on acute myocardial ischemia: Novel modulators of endogenous H2S production. Antioxidants and Redox Signaling 12: 1155–65.
   PubMed Web of Science ®Google Scholar
• Wu WJ, Jia WW, Liu XH, et al. (2016). S-propargyl-cysteine attenuates inflammatory response in rheumatoid arthritis by modulating the Nrf2-ARE signaling pathway. Redox Biol 10:157–67.
   PubMed Web of Science ®Google Scholar
• Xin H, Wang M, Tang W, et al. 2016. Hydrogen Sulfide Attenuates Inflammatory Hepcidin by Reducing IL-6 Secretion and Promoting SIRT1-Mediated STAT3 Deacetylation. Antioxidants and Redox Signaling.
   Google Scholar
• Yang J, Shen D, Wei Y, et al. (2015). Monodisperse core-shell structured magnetic mesoporous aluminosilicate nanospheres with large dendritic mesochannels. Nano Res 8: 2503–14.
   Web of Science ®Google Scholar
• Zheng Y, Liu H, Ma G, et al. (2011). Determination of S-propargyl-cysteine in rat plasma by mixed-mode reversed-phase and cation-exchange HPLC-MS/MS method and its application to pharmacokinetic studies. J Pharm Biomed Anal 54: 1187–91.
   PubMed Web of Science ®Google Scholar
• Zheng YT, Zhu JH, Ma G, et al. (2012). Preclinical assessment of the distribution, metabolism, and excretion of S-propargyl-cysteine, a novel H 2S donor, in Sprague-Dawley rats. Acta Pharmacol Sin 33: 839–44.
   PubMed Web of Science ®Google Scholar
• Zhu YZ, Zhong JW, Ho P, et al. (2007). Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats. Journal of Applied Physiology 102:261–8.
   PubMed Web of Science ®Google Scholar