Advanced search
Publication Cover
Drug Delivery Volume 28, 2021 - Issue 1
Submit an article Journal homepage
1,997
Views
12
CrossRef citations to date
0
Altmetric
Research Article

UTMD promoted local delivery of miR-34a-mimic for ovarian cancer therapy

Yue Lia The First Affiliated Hospital, Medical Imaging Centre, Hengyang Medical School, University of South China, Hengyang, Hunan, China;b Institute of Medical Imaging, University of South China, Hengyang, China;c Laboratory of Ultrasound Molecular Imaging, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, ChinaView further author information
,
Meng Dua The First Affiliated Hospital, Medical Imaging Centre, Hengyang Medical School, University of South China, Hengyang, Hunan, China;b Institute of Medical Imaging, University of South China, Hengyang, ChinaView further author information
,
Jinghui Fangc Laboratory of Ultrasound Molecular Imaging, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, ChinaView further author information
,
Jia Zhoud The First Affiliated Hospital, Department of Ultrasound Medicine, Hengyang Medical School, University of South China, Hengyang, Hunan, ChinaView further author information
&
Zhiyi Chena The First Affiliated Hospital, Medical Imaging Centre, Hengyang Medical School, University of South China, Hengyang, Hunan, China;b Institute of Medical Imaging, University of South China, Hengyang, ChinaCorrespondence[email protected]
View further author information
Pages 1616-1625 | Received 13 May 2021, Accepted 05 Jul 2021, Published online: 28 Jul 2021

References

  • Bartel DP. (2009). MicroRNAs: target recognition and regulatory functions. Cell 136:215–33.
  • Bez M, Foiret J, Shapiro G, et al. (2019). Nonviral ultrasound-mediated gene delivery in small and large animal models. Nat Protoc 14:1015–26.
  • Bhutto DF, Murphy EM, Priddy MC, et al. (2018). Effect of molecular weight on sonoporation-mediated uptake in human cells. Ultrasound Med Biol 44:2662–72.
  • De Cock I, Zagato E, Braeckmans K, et al. (2015). Ultrasound and microbubble mediated drug delivery: acoustic pressure as determinant for uptake via membrane pores or endocytosis. J Control Release 197:20–8.
  • Dimcevski G, Kotopoulis S, Bjånes T, et al. (2016). A human clinical trial using ultrasound and microbubbles to enhance gemcitabine treatment of inoperable pancreatic cancer. J Control Release 243:172–81.
  • He L, He X, Lim LP, et al. (2007). A microRNA component of the p53 tumour suppressor network. Nature 447:1130–4.
  • Helfield B, Chen X, Watkins SC, Villanueva FS. (2016). Biophysical insight into mechanisms of sonoporation. Proc Natl Acad Sci USA 113:9983–8.
  • Hong DS, Kang Y-K, Borad M, et al. (2020). Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours. Br J Cancer 122:1630–7.
  • Jackstadt R, van Hooff SR, Leach JD, et al. (2019). Epithelial NOTCH signaling rewires the tumor microenvironment of colorectal cancer to drive poor-prognosis subtypes and metastasis. Cancer Cell 36:319–36.
  • Jang E, Kim E, Son H-Y, et al. (2016). Nanovesicle-mediated systemic delivery of microRNA-34a for CD44 overexpressing gastric cancer stem cell therapy. Biomaterials 105:12–24.
  • Krol J, Loedige I, Filipowicz W. (2010). The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 11:597–610.
  • Li Y, Chen Z, Ge S. (2021). Sonoporation: underlying mechanisms and applications in cellular regulation. BIO Integration 2:29–36.
  • Liufu C, Li Y, Lin Y, et al. (2020). Synergistic ultrasonic biophysical effect-responsive nanoparticles for enhanced gene delivery to ovarian cancer stem cells. Drug Deliv 27:1018–33.
  • Liufu C, Li Y, Tu J, et al. (2019). Echogenic PEGylated PEI-loaded microbubble as efficient gene delivery system. Int J Nanomedicine 14:8923–41.
  • Meijering BD, Juffermans LJ, van Wamel A, et al. (2009). Ultrasound and microbubble-targeted delivery of macromolecules is regulated by induction of endocytosis and pore formation. Circ Res 104:679–87.
  • Meng L, Liu X, Wang Y, et al. (2019). Sonoporation of cells by a parallel stable cavitation microbubble array. Adv Sci 6:1900557.
  • Qiu Y, Zhang C, Tu J, Zhang D. (2012). Microbubble-induced sonoporation involved in ultrasound-mediated DNA transfection in vitro at low acoustic pressures. J Biomech 45:1339–45.
  • Rong N, Zhou H, Liu R, et al. (2018). Ultrasound and microbubble mediated plasmid DNA uptake: a fast, global and multi-mechanisms involved process. J Control Release 273:40–50.
  • Shapiro G, Wong AW, Bez M, et al. (2016). Multiparameter evaluation of in vivo gene delivery using ultrasound-guided, microbubble-enhanced sonoporation. J Control Release 223:157–64.
  • Song K-H, Fan AC, Brlansky JT, et al. (2015). High efficiency molecular delivery with sequential low-energy sonoporation bursts. Theranostics 5:1419–27.
  • Su Q, Kumar V, Sud N, Mahato RI. (2018). MicroRNAs in the pathogenesis and treatment of progressive liver injury in NAFLD and liver fibrosis. Adv Drug Deliv Rev 129:54–63.
  • Ventura A, Jacks T. (2009). MicroRNAs and cancer: short RNAs go a long way. Cell 136:586–91.
  • Xiao C, Wang K, Xu Y, et al. (2018). Transplanted mesenchymal stem cells reduce autophagic flux in infarcted hearts via the exosomal transfer of miR-125b. Circ Res 123:564–78.
  • Xie A, Wu MD, Cigarroa G, et al. (2016). Influence of DNA-microbubble coupling on contrast ultrasound-mediated gene transfection in muscle and liver. J Am Soc Echocardiogr 29:812–8.
  • Yang F, Li Y, Liufu C, et al. (2018). Preparation of cationic lipid-coated ultrasound contrast agents and noninvasive gene transfection via ultrasound-targeted microbubble destruction. Curr Pharm Des 24:3587–95.
  • Zeng Z, Xia L, Fan X, et al. (2019). Platelet-derived miR-223 promotes a phenotypic switch in arterial injury repair. J Clin Invest 129:1372–86.
  • Zhang H, Li Y, Rao F, et al. (2020). A novel UTMD system facilitating nucleic acid delivery into MDA-MB-231 cells. Biosci Rep 40:BSR20192573.
  • Zhou Z, Zhang P, Ren J, et al. (2013). Synergistic effects of ultrasound-targeted microbubble destruction and TAT peptide on gene transfection: an experimental study in vitro and in vivo. J Control Release 170:437–44.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.