An overview of the nutritional and therapeutic properties of amaranth

References

• Patil, S. B.; Jena, S. Utilization of Underrated Pseudo-Cereals of North East India: A Systematic Review. Nutr. Food Sci. 2020, 50(6), 1229–1240. DOI: 10.1108/NFS-11-2019-0339.
   Web of Science ®Google Scholar
• Chauhan, A.; Saxena, D. C.; Singh, S.; Yildiz, F. Physical, Textural, and Sensory Characteristics of Wheat and Amaranth Flour Blend Cookies. Cogent Food Agric. 2016, 2(1), 1125773. DOI: 10.1080/23311932.2015.1125773.
   Google Scholar
• Smyth, S. J.; Webb, S. R.; Phillips, P. W. The Role of Public-Private Partnerships in Improving Global Food Security. Global Food Secur. 2021, 31, 100588. DOI: 10.1016/j.gfs.2021.100588.
   Google Scholar
• Shelef, O.; Weisberg, P. J.; Provenza, F. D. The Value of Native Plants and Local Production in an Era of Global Agriculture. Front Plant Sci. 2017, 8, 2069. DOI: 10.3389/fpls.2017.02069.
   PubMed Web of Science ®Google Scholar
• Maurya, N. K.; Arya, P. Amaranthus Grain Nutritional Benefits: A Review. J. Pharmacogn. Phytochem. 2018, 7(2), 2258–2262.
   Google Scholar
• Ruth, O. N.; Unathi, K.; Nomali, N.; Chinsamy, M. Underutilization versus Nutritional-Nutraceutical Potential of the Amaranthus Food Plant: A Mini-Review. Applied Sciences. 2021, 11(15), 6879. DOI: 10.3390/app11156879.
   Google Scholar
• Jimoh, M. O.; Afolayan, A. J.; Lewu, F. B. Toxicity and Antimicrobial Activities of Amaranthus Caudatus L. (Amaranthaceae) Harvested from Formulated Soils at Different Growth Stages. J. Evid. Based Complementary Altern. Med. 2020, 25, 1–11. CrossRef. DOI: 10.1177/2515690X20971578.
   Google Scholar
• Caeiro, C.; Pragosa, C.; Cruz, M. C.; Pereira, C. D.; Pereira, S. G.; Huerta, J. M. The Role of Pseudocereals in Celiac Disease: Reducing Nutritional Deficiencies to Improve Well-Being and Health. J. Nutr. Metab. 2022, 2022, 1–8. DOI: 10.1155/2022/8502169.
   Web of Science ®Google Scholar
• Graziano, S.; Agrimonti, C.; Marmiroli, N.; Gullì, M. Utilisation and Limitations of Pseudocereals (Quinoa, Amaranth, and Buckwheat) in Food Production: A Review. Trends Food Sci. Technol. 2022, 125, 154–165. DOI: 10.1016/j.tifs.2022.04.007.
   Web of Science ®Google Scholar
• Das, S. Amaranthus: A Promising Crop of Future; Springer: Singapore, 2016. DOI: 10.1007/978-981-10-1469-7.
   Google Scholar
• Chandra, S.; Jain, A. K. Foundations of Ethnobotany (21st Century Perspective); Scientific Publishers: Jodhpur, India, 2017.
   Google Scholar
• Kauffman, C. S.; Weber, L. E. Grain Amaranth. In Advances in New Crops; Timber Press: Portland, OR, 1990; pp. 127–139.
   Google Scholar
• Tovar-Pérez, E. G.; Lugo-Radillo, A.; Aguilera-Aguirre, S. Amaranth Grain as a Potential Source of Biologically Active Peptides: A Review of Their Identification, Production, Bioactivity, and Characterization. Food Rev. Int. 2019, 35(3), 221–245. DOI: 10.1080/87559129.2018.1514625.
   Google Scholar
• Garrido-Galand, S.; Asensio-Grau, A.; Calvo-Lerma, J.; Heredia, A.; Andrés, A. The Potential of Fermentation on Nutritional and Technological Improvement of Cereal and Legume Flours: A Review. Food Res. Int. 2021, 145, 110398. DOI: 10.1016/j.foodres.2021.110398.
   PubMed Web of Science ®Google Scholar
• Bender, D.; Schönlechner, R. Recent Developments and Knowledge in Pseudocereals Including Technological Aspects. Acta Aliment. 2021, 50(4), 583–609. DOI: 10.1556/066.2021.00136.
   Web of Science ®Google Scholar
• Vega‐Gálvez, A.; Miranda, M.; Vergara, J.; Uribe, E.; Puente, L.; Martínez, E. A. Nutrition Facts and Functional Potential of Quinoa (Chenopodium Quinoa Willd.), an Ancient Andean Grain: A Review. J. Sci. Food Agric. 2010, 90(15), 2541–2547. DOI: 10.1002/jsfa.4158.
   PubMed Web of Science ®Google Scholar
• Tang, Y.; Tsao, R. Phytochemicals in Quinoa and Amaranth Grains and Their Antioxidant, Anti‐Inflammatory, and Potential Health Beneficial Effects: A Review. Mol. Nutr. Food Res. 2017, 61(7), 1600767. DOI: 10.1002/mnfr.201600767.
   Web of Science ®Google Scholar
• Mondor, M.; Melgar-Lalanne, G.; Hernández-Álvarez, A. J. Cold Pressed Amaranth (Amaranthus Tricolor) Oil. In Cold Pressed Oils, Green Technology, Bioactive Compounds, Functionality, and Applications; Academic Press: Cambridge, Massachusetts, United States, 2020; 113–127.
   Google Scholar
• van Lieshout, G. A.; Lambers, T. T.; Bragt, M. C.; Hettinga, K. A. How Processing May Affect Milk Protein Digestion and Overall Physiological Outcomes: A Systematic Review. Crit. Rev. Food Sci. Nutr. 2020, 60(14), 2422–2445. DOI: 10.1080/10408398.2019.1646703.
   PubMed Web of Science ®Google Scholar
• Marquez-Molina, O.; Lopez-Martinez, L. X. Effect of Various Process Conditions on the Nutritional and Bioactive Compounds of Amaranth. Nutritional Value Of Amaranth. 2020, 1–11.
   Google Scholar
• Singh, A.; Kumari, A.; Chaudhary, H. K. Amaranth, Buckwheat, and Chenopodium: The “ABC” Nutraceuticals of Northwestern Himalayas. Agric. Biotechnol: Latest Research And Trends. 2021, 587–634.
   Google Scholar
• Twinomuhwezi, H.; Awuchi, C. G.; Rachael, M. Comparative Study of the Proximate Composition and Functional Properties of Composite Flours of Amaranth, Rice, Millet, and Soybean. Am. J. Food Sci. Nutr. 2020, 6(1), 6–19.
   Google Scholar
• Caselato–Sousa, V. M.; Amaya–Farfán, J. State of Knowledge on Amaranth Grain: A Comprehensive Review. Journal Of Food Science. 2012, 77(4), R93–R104. DOI: 10.1111/j.1750-3841.2012.02645.x.
   PubMed Web of Science ®Google Scholar
• Eshete, M. A.; Asfaw, Z.; Kelbessa, E. A Review on Taxonomic and Use Diversity of the Family Amaranthaceae in Ethiopia. J. Med. Plants Sci. 2016, 4(2), 185–194.
   Google Scholar
• Ogwu, M. C. Value of Amaranthus [L.] Species in Nigeria. Nutritional Value Of Amaranth. 2020, 1–21.
   Google Scholar
• Das, S.; Das, S. Amaranths: The Crop of Great Prospect. Amaranthus: A Promising Crop Of Future. 2016, 13–48.
   Google Scholar
• Olaniyi, J. O.; Adelasoye, K. A.; Jegede, C. O. Influence of Nitrogen Fertilizer on the Growth, Yield and Quality of Grain Amaranth Varieties. World J. Agric. Sci. 2008, 4(4), 506–513.
   Google Scholar
• Soriano-García, M.; Aguirre-Díaz, I. S. Nutritional Functional Value and Therapeutic Utilization of Amaranth. In Nutritional Value of Amaranth; IntechOpen, 2019.
   Google Scholar
• Tahmasebi, A.; Ebrahimie, E.; Pakniyat, H.; Ebrahimi, M.; Mohammadi-Dehcheshmeh, M. Tissue-specific transcriptional biomarkers in medicinal plants: Application of large-scale meta-analysis and computational systems biology. Gene. 2019, 691, 114–124. DOI: 10.1016/j.gene.2018.12.056.
   PubMed Web of Science ®Google Scholar
• Kumar, N.; Kumari, P.; Ali, M.; Naik, A.; Lone, S.; Lathwal, S. Phytobiotics and Reproductive Performance of Livestock. Phytobiotics & Animal Production. International Books And Periodicals Supply Services. 2019, 97, 108.
   Google Scholar
• Bhowmik, D.; Gopinath, H.; Kumar, B. P.; Kumar, K. S. Medicinal Uses of Punica Granatum and Its Health Benefits. J. Pharmacogn. Phytochem. 2013, 1(5), 28–35.
   Google Scholar
• Schnetzler, K. A. Food Uses and Amaranth Product Research: A Comprehensive Review. Amaranth Biol. Chem. Techno. 2018, 155–184.
   Google Scholar
• Capriles, V. D.; Arêas, J. A. G. Novel Approaches in Gluten‐Free Breadmaking: Interface Between Food Science, Nutrition, and Health. Compr. Rev. Food Sci. Food Saf. 2014, 13(5), 871–890. DOI: 10.1111/1541-4337.12091.
   Web of Science ®Google Scholar
• Fardet, A. New Hypotheses for the Health-Protective Mechanisms of Whole-Grain Cereals: What is Beyond Fibre? Nutr. res. rev. 2010, 23(1), 65–134. DOI: 10.1017/S0954422410000041.
   PubMed Web of Science ®Google Scholar
• Balakrishnan, G.; Schneider, R. G. The Role of Amaranth, Quinoa, and Millets for the Development of Healthy, Sustainable Food Products—A Concise Review. Foods. 2022, 11(16), 2442. DOI: 10.3390/foods11162442.
   PubMed Web of Science ®Google Scholar
• Siddiqui, S. A.; Mahmud, M. C.; Abdi, G.; Wanich, U.; Farooqi, M. Q. U.; Settapramote, N.; Wani, S. A. New Alternatives from Sustainable Sources to Wheat in Bakery Foods: Science, Technology, and Challenges. J. Food Biochem. 2022, 46(9), e14185. DOI: 10.1111/jfbc.14185.
   PubMed Web of Science ®Google Scholar
• Coelho, L. M.; Silva, P. M.; Martins, J. T.; Pinheiro, A. C.; Vicente, A. A. Emerging Opportunities in Exploring the Nutritional/Functional Value of Amaranth. Food Funct. 2018, 9(11), 5499–5512. DOI: 10.1039/C8FO01422A.
   PubMed Web of Science ®Google Scholar
• Wołosik, K. A. T. A. R. Z. Y. N. A.; Knaś, M.; Zalewska, A.; Niczyporuk, M.; Przystupa, A. W. The Importance and Perspective of Plant-Based Squalene in Cosmetology. J. Cosmet. Sci. 2013, 64(1), 59–66.
   PubMed Web of Science ®Google Scholar
• Chao, J. Skincare for Your Soul: Achieving Outer Beauty and Inner Peace with Korean Skincare; Mango Media Inc: Coral Gables, FL, USA, 2021.
   Google Scholar
• Pasko, P.; Sajewicz, M.; Gorinstein, S.; Zachwieja, Z. Analysis of Selected Phenolic Acids and Flavonoids in Amaranthus Cruentus and Chenopodium Quinoa Seeds and Sprouts by HPLC. Acta Chromatograph. 2008, 20(4), 661–672. DOI: 10.1556/AChrom.20.2008.4.11.
   Web of Science ®Google Scholar
• Kraujalis, P.; Venskutonis, P. R. Optimization of Supercritical Carbon Dioxide Extraction of Amaranth Seeds by Response Surface Methodology and Characterization of Extracts Isolated from Different Plant Cultivars. J. Supercrit. Fluids. 2013, 73, 80–86. DOI: 10.1016/j.supflu.2012.11.009.
   Web of Science ®Google Scholar
• Ryan, E.; Galvin, K.; O’Connor, T. P.; Maguire, A. R.; O’Brien, N. M. Phytosterol, squalene, tocopherol content and fatty acid profile of selected seeds, grains, and legumes. Plant Foods Hum. Nutr. 2007, 62(3), 85–91. DOI: 10.1007/s11130-007-0046-8.
   PubMed Web of Science ®Google Scholar
• He, H.-P.; Cai, Y.; Sun, M.; Corke, H. Extraction and Purification of Squalene from Amaranthus Grain. J. Agric. Food. Chem. 2002, 50(2), 368–372. DOI: 10.1021/jf010918p.
   PubMed Web of Science ®Google Scholar
• Stone, L. A.; Lorenz, K. The Starch of Amaranthus: Physiochemical Properties and Functional Characteristics. Starch. 1984, 36(7), 232–237. DOI: 10.1002/star.19840360704.
   Google Scholar
• Oleszek, W.; Junkuszew, M.; Stochmal, A. Determination and Toxicity of Saponins from Amaranthus Cruentus Seeds. J. Agric. Food Chem. 1999, 47(9), 3685–3687. DOI: 10.1021/jf990182k.
   PubMed Web of Science ®Google Scholar
• Baraniak, J.; Kania-Dobrowolska, M. The Dual Nature of Amaranth—Functional Food and Potential Medicine. Foods. 2022, 11(4), 618. DOI: 10.3390/foods11040618.
   PubMed Web of Science ®Google Scholar
• Zehravi, M.; Karthika, C.; Azad, A. K.; Ahmad, Z.; Khan, F. S.; Rahman, M. S.; Rahman, M. H. A Background Search on the Potential Role of Scutellaria and Its Essential Oils. Biomed Res. Int. 2022, 2022, 1–12. DOI: 10.1155/2022/7265445.
   Web of Science ®Google Scholar
• Elufioye, T. O.; Habtemariam, S.; Adejare, A. Chemistry and Pharmacology of Alkylamides from Natural Origin. Rev. Bras. Farmacogn. 2020, 30(5), 622–640. DOI: 10.1007/s43450-020-00095-5.
   PubMedGoogle Scholar
• Sarker, U.; Oba, S. Color Attributes, Betacyanin, and Carotenoid Profiles, Bioactive Components, and Radical Quenching Capacity in Selected Amaranthus Gangeticus Leafy Vegetables. Sci. Rep. 2021, 11(1), 11559. DOI: 10.1038/s41598-021-91157-8.
   PubMed Web of Science ®Google Scholar
• Bachar, S. C.; Bachar, R.; Jannat, K.; Jahan, R.; Rahmatullah, M. Hepatoprotective Natural Products. Annu. Rep. Med. Chem. 2020, 55, 207–249.
   Web of Science ®Google Scholar
• Mburu, M. W.; Gikonyo, N. K.; Kenji, G. M.; Mwasaru, A. M. Nutritional and Functional Properties of a Complementary Food Based on Kenyan Amaranth Grain (Amaranthus Cruentus). Afr. J. Food Agric. Nutr. Dev. 2012, 12(2), 5959–5977. DOI: 10.18697/ajfand.50.9800.
   Google Scholar
• Kim, N. H.; Kim, Y. S.; Jung, D. H.; Kim, J. S. KIOM-79 Prevents Xylose-Induced Lens Opacity and Inhibits TGF-Beta2 in Human Lens Epithelial Cells Cultured Under High Glucose. J. Ethnopharmacol. 2010, 130(3), 599–606. DOI: 10.1016/j.jep.2010.05.052.
   PubMed Web of Science ®Google Scholar
• Zeng, L.; Xiang, R.; Fu, C.; Qu, Z.; Liu, C. The Regulatory Effect of Chlorogenic Acid on Gut-Brain Function and Its Mechanism: A Systematic Review. Biomed. Pharmacother. 2022, 149, 112831. DOI: 10.1016/j.biopha.2022.112831.
   PubMed Web of Science ®Google Scholar
• Park, S. J.; Sharma, A.; Lee, H. J. A Review of Recent Studies on the Antioxidant Activities of a Third-Millennium Food: Amaranthus Spp. Antioxidants. 2020, 9(12), 1236. DOI: 10.3390/antiox9121236.
   Web of Science ®Google Scholar
• Szwejkowska, B.; Bielski, S. Warto´s´c prozdrowotna nasion szarłatu (Amaranthus cruentus L.). Postepy Fitoter. 2012, 4, 240–243.
   Google Scholar
• Sarker, U.; Oba, S. Polyphenol and flavonoid profiles and radical scavenging activity in leafy vegetable Amaranthus gangeticus. BMC. Plant Biol. 2020, 20(1), 499. CrossRef] [PubMed. DOI: 10.1186/s12870-020-02700-0.
   PubMed Web of Science ®Google Scholar
• Manólio Soares, R. A.; Mendonça, S.; Andrade de Castro, L. I.; Cardoso Corrêa Carlos Menezes, A. C.; Gomes Arêas, J. A. Major Peptides from Amaranth (Amaranthus Cruentus) Protein Inhibit HMG-CoA Reductase Activity. Int. J. Mol. Sci. 2015, 16(2), 4150. CrossRef. DOI: 10.3390/ijms16024150.
   PubMed Web of Science ®Google Scholar
• Hsiao, L. W.; Tsay, G. J.; Mong, M. C.; Liu, W. H.; Yin, M. C. Aqueous Extract Prepared from Steamed Red Amaranth (Amaranthus Gangeticus L.) Leaves Protected Human Lens Cells Against High Glucose Induced Glycative and Oxidative Stress. J. Food Sci. 2021, 86(8), 3686–3697. CrossRef] [PubMed. DOI: 10.1111/1750-3841.15822.
   PubMed Web of Science ®Google Scholar
• Amornrit, W.; Santiyanont, R. Effect of Amaranthus on Advanced Glycation End-Products Induced Cytotoxicity and Proinflammatory Cytokine Gene Expression in SH-SY5Y Cells. Molecules. 2015, 20(9), 17288. CrossRef] [PubMed. DOI: 10.3390/molecules200917288.
   PubMed Web of Science ®Google Scholar
• Jimoh, M. O.; Afolayan, A. J.; Lewu, F. B. Suitability of Amaranthus Species for Alleviating Human Dietary Deficiencies. South African J. Of Bot. 2018, 115, 65–73. DOI: 10.1016/j.sajb.2018.01.004.
   Web of Science ®Google Scholar
• B, A.; Gremaud, G.; Baumgartner, M.; Rein, D.; Monnard, I.; Kratky, E.; Geiger, W.; Burri, J.; Dionisi, F.; Allan, M., et al. Cholesterol-Lowering Properties of Amaranth Grain and Oil in Hamsters. Int. J. Vitam. Nutr. Res. 2003, 73(1), 39–47.
   PubMed Web of Science ®Google Scholar
• Devaraj, V. C.; Krishna, B. G. Gastric Antisecretory and Cytoprotective Effects of Leaf Extracts of Amaranthus Tricolor Linn in Rats. J Chin Integr Med. 2011, 9(9), 1031–1038. DOI: 10.3736/jcim20110915.
   PubMedGoogle Scholar
• Baskar, A. A.; Al Numair, K. S.; Alsaif, M. A.; Ignacimuthu, S. In vitro Antioxidant and Antiproliferative Potential of Medicinal Plants Used in Traditional Indian Medicine to Treat Cancer. Redox Rep. 2012, 17(4), 145–156. DOI: 10.1179/1351000212Y.0000000017.
   PubMed Web of Science ®Google Scholar