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Research Article

Intraperitoneal Versus Intravenous Dexmedetomidine for Postoperative Analgesia Following Laparoscopic Sleeve Gastrectomy Surgery: A prospective, Randomized Controlled trial

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Pages 120-127 | Received 21 Apr 2022, Accepted 21 Jan 2023, Published online: 07 Feb 2023

References

  • Alamdari NM, Bakhtiyari M, Gholizadeh B, et al. Analgesic effect of intraperitoneal bupivacaine hydrochloride after laparoscopic sleeve gastrectomy: a randomized clinical trial. J Gastrointest Surg. 2018;22(3):396–401.
  • Omar I, Abualsel A. Efficacy of intraperitoneal instillation of bupivacaine after bariatric surgery: randomized controlled trial. Obes Surg. 2019;29(6):1735–1741.
  • Wu R, Haggar F, Porte NG, et al. Assessing the feasibility of a randomised, double-blinded, placebo-controlled trial to investigate the role of intraperitoneal ropivacaine in gastric bypass surgery: a protocol. BMJ open. 2014;4(8):e005823.
  • Mostafa RH, Mekki YMH. Comparative evaluation of intraperitoneal bupivacaine and bupivacaine ketamine combined with lung recruitment for reducing postoperative shoulder pain in laparoscopic cholecystectomy. Egyptian J Anaesth. 2018;34(4):159–164.
  • Ruiz-Tovar J, Muñoz JL, Gonzalez J, et al. Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intravenous analgesia). Surg Endosc. 2017;31(1):231–236.
  • Kahokehr A, Sammour T, Soop M, et al. Intraperitoneal local anaesthetic in abdominal surgery–a systematic review. ANZ J Surg. 2011;81(4):237–245.
  • Chilkoti GT, Kumar M, Mohta M, et al. Comparison of postoperative analgesic efficacy of low-dose bolus intravenous dexmedetomidine and intraperitoneal dexmedetomidine with bupivacaine in patients undergoing laparoscopic cholecystectomy: a randomised, controlled trial. Indian J Anaesth. 2019;63(2):106–113.
  • Elnabtity AM, Ibrahim M. Intraperitoneal dexmedetomidine as an adjuvant to bupivacaine for postoperative pain management in children undergoing laparoscopic appendectomy: a prospective randomized trial. Saudi J Anaesth. 2018;12(3):399–405.
  • Schnabel A, Reichl SU, Weibel S, et al. Efficacy and safety of dexmedetomidine in peripheral nerve blocks: a meta-analysis and trial sequential analysis. Eur J Anaesthesiol. 2018;35(10):745–758.
  • Zhao Z-F, Du L, Wang D-X. Effects of dexmedetomidine as a perineural adjuvant for femoral nerve block: a systematic review and meta-analysis. PloS One. 2020;15(10):e0240561.
  • Abdallah F, Brull R. Facilitatory effects of perineural dexmedetomidine on neuraxial and peripheral nerve block: a systematic review and meta-analysis. Br J Anaesth. 2013;110(6):915–925.
  • Abdallah FW, Dwyer T, Chan VW, et al. IV and perineural dexmedetomidine similarly prolong the duration of analgesia after interscalene brachial plexus blocka randomized, three-arm, triple-masked, placebo-controlled trial. Anesthesiology. 2016;124(3):683–695.
  • Brummett CM, Hong EK, Janda AM, et al. Perineural dexmedetomidine added to ropivacaine for sciatic nerve block in rats prolongs the duration of analgesia by blocking the hyperpolarization-activated cation current. Anesthesiology. 2011;115(4):836–843.
  • Yabuki A, Higuchi H, Yoshitomi T, et al. Locally injected dexmedetomidine induces vasoconstriction via peripheral α-2A adrenoceptor subtype in Guinea pigs. Reg Anesth Pain Med. 2014;39(2):133–136.
  • Nakamura M, Ferreira SH. Peripheral analgesic action of clonidine: mediation by release of endogenous enkephalin-like substances. Eur J Pharmacol. 1988;146(2–3):223–228.
  • Oza VP, Parmar V, Badheka J, et al. Comparative study of postoperative analgesic effect of intraperitoneal instillation of dexmedetomidine with bupivacaine and bupivacaine alone after laparoscopic surgery. J Minim Access Surg. 2016;12(3):260–264.
  • Fares KM, Mohamed SA-E, Abd El-Rahman AM, et al. Efficacy and safety of intraperitoneal dexmedetomidine with bupivacaine in laparoscopic colorectal cancer surgery, a randomized trial. Pain Med. 2015;16(6):1186–1194.
  • Shukla U, Prabhakar T, Malhotra K, et al. Intraperitoneal bupivacaine alone or with dexmedetomidine or tramadol for post-operative analgesia following laparoscopic cholecystectomy: a comparative evaluation. Indian J Anaesth. 2015;59(4):234–239.
  • Narasimham ML, Rao BD. Comparison of intraperitoneal bupivacaine alone or with dexmedetomidine or tramadol for post-operative analgesia following laparoscopic cholecystectomy. Indian J Clin Anaesth. 2017;4(1):143–146.
  • Shin HJ, Do SH, Lee JS, et al. Comparison of intraoperative sedation with dexmedetomidine versus propofol on acute postoperative pain in total knee arthroplasty under spinal anesthesia: a randomized trial. Anesth Analg. 2019;129(6):1512–1518.
  • Kang R, Jeong JS, Yoo JC, et al. Effective dose of intravenous dexmedetomidine to prolong the analgesic duration of interscalene brachial plexus block: a single-center, prospective, double-blind, randomized controlled trial. Reg Anesth Pain Med. 2018;43(5):488–495.
  • Sivakumar RK, Panneerselvam S, Cherian A, et al. Perineural vs. intravenous dexmedetomidine as an adjunct to bupivacaine in ultrasound guided fascia iliaca compartment block for femur surgeries: a randomised control trial. Indian J Anaesth. 2018;62(11):851–857.
  • Thakur A, Sharma C, Bijender D, et al. Analgesic efficacy of intraperitoneal vs intravenous dexmedetomidine as adjuvant to levobupivacaine 0.25% in laparoscopic cholecystectomy under general Anaesthesia. Int J Med Anesthesiol. 2020;3(1):255–260.
  • Sharma K, Kumar M, Gandhi R. Effect of single-dose dexmedetomidine on intraoperative hemodynamics and postoperative recovery during pediatric adenotonsillectomy. Anesth Essays Res. 2019;13(1):63–67.
  • Belleville JP, Ward DS, Bloor BC, et al. Effects of intravenous dexmedetomidine in humans: i. Sedation, ventilation, and metabolic rate. Anesthesiology. 1992;77(6):1125–1133.
  • Abdel-Rahman KA-B, Abd-Elshafy SK, Sayed JA. Effect of two different doses of dexmedetomidine on the incidence of emergence agitation after strabismus surgery: a randomized clinical trial. Rev Bras Anestesiol. 2018;68(6):571–576.
  • Ohtani N, Kida K, Shoji K, et al. Recovery Profiles from Dexmedetomidine as a General Anesthetic Adjuvant in Patients Undergoing Lower Abdominal Surgery. Anesth Analg. 2008;107(6):1871–1874.
  • Mostafa RH, Ibrahim IM, Ayoub AH. Effect of perioperative dexmedetomidine infusion on blood glucose levels in non-diabetic morbid obese patients undergoing laparoscopic bariatric surgery. Egyptian J Anaesth. 2018;34(3):75–81.
  • Bhattacharjee DP, Nayek SK, Dawn S, et al. Effects of dexmedetomidine on haemodynamics in patients undergoing laparoscopic cholecystectomy-A comparative study. J Anaesth Clin Pharmacol. 2010;26(1):45–48.
  • Indira P, Raghu R, Swetha A. Effects of preoperative single bolus dose of dexmedetomidine on perioperative hemodynamics in elective laparoscopic cholecystectomy. Indian J Clin Anaesth. 2019;6(1):47–54.