Perioperative oral pregabalin or clonidine in patients undergoing lumbar spine posterior fusion: A randomized controlled trial

References

• Anvari ZT, Fereydouniyan NA, Imani F, et al. Effect of clonidine premed on blood loss in spine surgery. Anesth Pain. 2012;1(4):252–256. doi: 10.5812/aapm.2197
   PubMedGoogle Scholar
• Elgafy H, Bransford RJ, McGuire RA, et al. Blood loss in major spine surgery: are there effective measures to decrease massive hemorrhage in major spine fusion surgery? Spine. 2010;35(Supplement):S47–S56. doi: 10.1097/BRS.0b013e3181d833f6
   PubMedGoogle Scholar
• Szplaski M, Gunzburg R, Sztern B. An overview of blood-sparing techniques used in spine surgery during the perioperative period. Eur Spine J. 2004;13(1):S18–27. doi: 10.1007/s00586-004-0752-y
   PubMedGoogle Scholar
• Garcia RM, Cassinelli EH, Messerschmitt PJ, et al. A multimodal approach for postoperative pain management after lumbar decompression surgery: a prospective, randomized study. J Spinal Disord Tech. 2013;26(6):291–7. doi: 10.1097/BSD.0b013e318246b0a6
   PubMedGoogle Scholar
• Perkins FM, Kehlet H. Chronic pain as an outcome of surgery: a review of predictive factors. Anesthesiology. 2000;93(4):1123–33. doi: 10.1097/00000542-200010000-00038
   PubMed Web of Science ®Google Scholar
• Guignard B, Bossard AE, Coste C, et al. Acute opioid tolerance: intraoperative remifentanil increases postoperative pain and morphine requirement. Anesthesiology. 2000;93(2):409–417. doi: 10.1097/00000542-200008000-00019
   PubMed Web of Science ®Google Scholar
• Jiang H, Huang S, Song J, et al. Preoperative use of pregabalin for acute pain in spine surgery. A meta-analysis of randomized controlled trials. Medicine. 2017;96(11):111. doi: 10.1097/MD.0000000000006129
   Web of Science ®Google Scholar
• Feng D, Wei J, Luo J, et al. Preoperative single dose of pregabalin alleviate postoperative pain: systematic review and meta-analysis. Int J ClinExp Med. 2016;9(6):9665–9680.
   Google Scholar
• White PF. “The changing role of non-opioid analgesic techniques in the management of postoperative pain, “anesthesia and analgesia. Anesthesia & Analgesia. 2005;101(5S):S5–22. doi: 10.1213/01.ANE.0000177099.28914.A7
   PubMed Web of Science ®Google Scholar
• Demirhan A, Akkaya A, Tekelioglu UY, et al. Effect of Pregabalin and dexamethasone on postoperative analgesia after septoplasty. Pain Res Treat. 2014;2014:1–7. doi: 10.1155/2014/850794
   Google Scholar
• Gupta K, Sharma D, Gupta PK. Oral premedication with pregabalin or clonidine for hemodynamic stability during laryngoscopy and laparoscopic cholecystectomy: a comparative evaluation. Saudi J Anaesth. 2011;5(2):179–84. doi: 10.4103/1658-354X.82791
   PubMedGoogle Scholar
• Ramsay MA, Savege TM, Simpson BR, et al. Controlled sedation with alfaxalone-alphadolone. Br Med J. 1974;2(5920):656–659. doi: 10.1136/bmj.2.5920.656
   PubMed Web of Science ®Google Scholar
• Mathiesen O, Jorgensen DG, Hilsted KL, et al. Pregabalin and dexamethasone improve postoperative pain treatment after tonsillectomy. Acta Anaesthesiol Scand. 2011;55(3):297–305. doi: 10.1111/j.1399-6576.2010.02389.x
   PubMed Web of Science ®Google Scholar
• Kim JC, Choi YS, Kim KN, et al. Effective dose of peri-operative oral pregabalin as an adjunct to multimodal analgesic regimen in lumbar spinal fusion surgery. Spine. 2011;36(6):428–433. doi: 10.1097/BRS.0b013e3181d26708
   PubMed Web of Science ®Google Scholar
• Pan CF, Shen MY, Hsiao G, et al. Inhibitory mechanisms of gabapentin, an antiseizure drug, on platelet aggregation. J Pharm Pharmacol. 2007;59(9):1255–1261. doi: 10.1211/jpp.59.9.0010
   PubMed Web of Science ®Google Scholar
• Al-Uboody W. Pregabalin effects on cellular and humoral components of blood of mice. Bas J Vet Res. 2017;16(2):76–84. doi: 10.33762/bvetr.2017.143534
   Google Scholar
• Lee TC, Yang LC, Chen HJ. Effect of patient position and hypotensive anesthesia on inferior vena cava pressure. Spine. 1998;23(8):941–947. doi: 10.1097/00007632-199804150-00019
   PubMed Web of Science ®Google Scholar
• Fornai F, Blandizzi C, delTacca M. Central alpha-2 adrenoceptors regulate central and peripheral functions. Pharmacol Res. 1990;22(5):541–54. doi: 10.1016/S1043-6618(05)80046-5
   PubMed Web of Science ®Google Scholar
• Saxena A, Gupta P, Chaudhary L. Effect of pregabalin premedication on the laryngoscopic response and intra-operative hemodynamic variables in laparoscopic cholecystectomy: a randomized comparison of two doses. International Journal Of Scientific Study. 2016;4(5):75–80.
   Google Scholar
• Sundar AS, Kodali R, Sulaiman S, et al. The effects of preemptive pregabalin on attenuation of stress response to endotracheal intubation and opioid-sparing effect in patients undergoing off-pump coronary artery bypass grafting. Ann Card Anaesth. 2012;15(1):18–25. doi: 10.4103/0971-9784.91473
   PubMedGoogle Scholar
• Gunasekaran K, Paramswamy R. A comparative study of the effects of premedication with oral clonidine versus oral pregabalin in patients undergoing lumbar spine surgery. IJAA. 2018;5(1):68–76. doi: 10.21088/ijaa.2349.8471.5118.10
   Google Scholar
• Chaudhary A, Sanghvi K, Parikh H. Oral premedication with pregabalin and clonidine for hemodynamic stability during laryngoscopy: a comparative study. Int J Basic Clin Pharmacol. 2015;4(2):294–299. doi: 10.5455/2319-2003.ijbcp20150423
   Google Scholar
• Khurana G, Jindal P, Sharma JP, et al. Postoperative pain and long-term functional outcome after administration of gabapentin and pregabalin in patients undergoing spinal surgery. Spine. 2014;39(6):E363–8. doi: 10.1097/BRS.0000000000000185
   PubMed Web of Science ®Google Scholar
• Spreng UJ, Dahl V, Raeder J. Effect of a single dose of pregabalin on postoperative pain and preoperative anxiety in patients undergoing discectomy. Acta Anesthesiol Scan. 2011;55(5):571–576. doi: 10.1111/j.1399-6576.2011.02410.x
   PubMed Web of Science ®Google Scholar
• Liu B, Liu R, Wang L. A meta-analysis of the preoperative use of gabapentinoids for the treatment of acute postoperative pain following spinal surgery. Medicine. 2017;96(37):137. doi: 10.1097/MD.0000000000008031
   Web of Science ®Google Scholar
• Fujita N, Masaru Tobe M, Tsukamoto N, et al. Obata H A randomized placebo-controlled study of preoperative pregabalin for postoperative analgesia in patients with spinal surgery. J Clin Anesth. 2016 31;31:149–53. doi: 10.1016/j.jclinane.2016.01.010
   PubMed Web of Science ®Google Scholar
• Urban MK, Labib KM, Reid SC, et al. Pregabalin Did Not Improve Pain Management after Spinal Fusions. HSS J. 2018;14(1):41–46. doi: 10.1007/s11420-017-9584-2
   PubMedGoogle Scholar
• Jiaqi H, Huang D, Minpu L, et al. Effects of a single dose of preoperative pregabalin and gabapentin for acute postoperative pain: a network meta-analysis of randomized controlled trials. JPR. 2018;11:2633–2643. doi: 10.2147/JPR.S170810
   Google Scholar
• Mathiesen O, Rasmussen ML, Direking G, et al. Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy: a randomized clinical trial. ActaAnesthesiol Scand. 2009;53(2):227–235. doi: 10.1111/j.1399-6576.2008.01821.x
   PubMed Web of Science ®Google Scholar
• Dong J, Li W, Wang Y. The effect of pregabalin on acute postoperative pain in patients undergoing total knee arthroplasty: a meta-analysis. Int J Surg. 2016;34:148–60. doi: 10.1016/j.ijsu.2016.08.521
   PubMed Web of Science ®Google Scholar
• Mishriky BM, Waldron NH, Habib AS. Impact of pregabalin on acute and persistent postoperative pain: a systematic review and meta-analysis. Br J Anaesth. 2015;114(1):10–31. doi: 10.1093/bja/aeu293
   PubMed Web of Science ®Google Scholar
• Eipe N, Penning J, Yazdi F, et al. Perioperative use of pregabalin for acute pain. systematic review and meta-analysis. Pain. 2015;156(7):1284–1300. doi: 10.1097/j.pain.0000000000000173
   PubMed Web of Science ®Google Scholar
• Tiippana EM, Hamunen K, Kontinen VK, et al. Do surgical patients benefit from perioperative gabapentin/pregabalin? A systematic review of efficacy and safety. AnesthAnalg. 2007;104(6):1545–1556. doi: 10.1213/01.ane.0000261517.27532.80
   Google Scholar
• Jokela R, Ahonen J, Tallgren M, et al. A randomized controlled trial of perioperative administration of pregabalin for pain after laparoscopic hysterectomy. Pain. 2008;134(1–2):106–112. doi: 10.1016/j.pain.2007.04.002
   PubMed Web of Science ®Google Scholar
• Grant MC, Betz M, Hulse M, et al. The effect of preoperative pregabalin on postoperative nausea and vomiting; a meta-analysis. AnesthAnalg. 2016;123(5):1100–1107. doi: 10.1213/ANE.0000000000001404
   Google Scholar
• Fink K, Dooley DJ, Meder WP, et al. Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex. Neuropharmacology. 2002;42(2):229–236. doi: 10.1016/S0028-3908(01)00172-1
   PubMed Web of Science ®Google Scholar