Original research: Dexmedetomidine versus ketamine in erector spinae plane block for postoperative analgesia following modified radical mastectomy: A prospective randomized controlled blinded study

References

• Łukasiewicz S, Czeczelewski M, Forma A, et al. Breast cancer—epidemiology, risk factors, classification, prognostic markers, and Current treatment strategies—an updated review. Cancers (Basel). 2021;13. 17 4287 10.3390/cancers13174287
   PubMed Web of Science ®Google Scholar
• López M, Padilla ML, García B, et al. Prevention of acute postoperative pain in breast cancer: a comparison between opioids versus ketamine in the intraoperatory analgesia. Pain Res Manag. 2021;2021:3290289. doi: 10.1155/2021/3290289
   PubMed Web of Science ®Google Scholar
• Clary Z, Nazir N, Butterworth J Transversus Abdominis Plane Block With Liposomal Bupivacaine Versus Thoracic Epidural for Postoperative Analgesia After Deep Inferior Epigastric Artery Perforator Flap–Based Breast Reconstruction. Ann Plast Surg. 2020;85:e24–e6. 6 10.1097/SAP.0000000000002423
   PubMed Web of Science ®Google Scholar
• Koo CH, Lee HT, Na HS, et al. Efficacy of erector spinae plane block for analgesia in thoracic surgery: a systematic review and meta-analysis. J Cardiothorac Vasc Anesth. 2022;36(5):1387–95. doi: 10.1053/j.jvca.2021.06.029
   PubMed Web of Science ®Google Scholar
• Hefni AF, Eldeek AM, Ismael SA, et al. Comparing effect of adding ketamine versus dexmedetomidine to bupivacaine in pecs-II block on postoperative pain control in patients undergoing breast surgery. Clin J Pain. 2022;38(9):568–74. doi: 10.1097/AJP.0000000000001055
   PubMed Web of Science ®Google Scholar
• Krishna Prasad GV, Khanna S, Jaishree SV. Review of adjuvants to local anesthetics in peripheral nerve blocks: Current and future trends. Saudi J Anaesth. 2020;14(1):77–84. doi: 10.4103/sja.SJA_423_19
   PubMed Web of Science ®Google Scholar
• Wang K, Wang LJ, Yang TJ, et al. Dexmedetomidine combined with local anesthetics in thoracic paravertebral block: a systematic review and meta-analysis of randomized controlled trials. Medicine (Baltimore). 2018;97(46):e13164. doi: 10.1097/MD.0000000000013164
   PubMed Web of Science ®Google Scholar
• Allen CA, Ivester JR Jr. Low-dose ketamine for postoperative pain management. J Perianesth Nurs. 2018;33:389–398. 4 10.1016/j.jopan.2016.12.009
   PubMed Web of Science ®Google Scholar
• Schnabel A, Poepping DM, Kranke P, et al. Efficacy and adverse effects of ketamine as an additive for paediatric caudal anaesthesia: a quantitative systematic review of randomized controlled trials. Br J Anaesth. 2011;107(4):601–11. doi: 10.1093/bja/aer258
   PubMed Web of Science ®Google Scholar
• Lashgarinia M, Naghibi K, Honarmand A, et al. Effect of ketamine as an adjuvant in ultrasound-guided supraclavicular brachial plexus block: a double-blind randomized clinical trial study. Adv Biomed Res. 2014;3(1):232. doi: 10.4103/2277-9175.145730
   PubMedGoogle Scholar
• El Mourad MB, Amer AF. Effects of adding dexamethasone or ketamine to bupivacaine for ultrasound-guided thoracic paravertebral block in patients undergoing modified radical mastectomy: a prospective randomized controlled study. Indian J Anaesth. 2018;62(4):285–91. doi: 10.4103/ija.IJA_791_17
   PubMed Web of Science ®Google Scholar
• Zhang J, He Y, Wang S, et al. The erector spinae plane block causes only cutaneous sensory loss on ipsilateral posterior thorax: a prospective observational volunteer study. BMC Anesthesiol. 2020;20(1):88. doi: 10.1186/s12871-020-01002-0
   PubMed Web of Science ®Google Scholar
• Gousheh M, Akhondzadeh R, Rashidi M, et al. Comparison of Dexmedetomidine and morphine as adjuvants to bupivacaine for epidural anesthesia in leg fracture surgery: a randomized clinical trial. Anesth Pain Med. 2019;9(4):e91480. doi: 10.5812/aapm.91480
   PubMedGoogle Scholar
• Rao J, Gao Z, Qiu G, et al. Nalbuphine and dexmedetomidine as adjuvants to ropivacaine in ultrasound-guided erector spinae plane block for video-assisted thoracoscopic lobectomy surgery: a randomized, double-blind, placebo-controlled trial. Medicine (Baltimore). 2021;100(32):e26962. doi: 10.1097/MD.0000000000026962
   PubMed Web of Science ®Google Scholar
• Abdel-Ghaffar HS, Kalefa MA, Imbaby AS Efficacy of ketamine as an adjunct to lidocaine in intravenous regional anesthesia. Reg Anesth Pain Med. 2014;39:418–422. 5 10.1097/AAP.0000000000000128
   PubMed Web of Science ®Google Scholar
• Neethirajan SGR, Kurada S, Parameswari A Efficacy of Dexmedetomidine as an adjuvant to Bupivacaine in ultrasound-guided Transverse Abdominis plane block for laparoscopic appendicectomy: a randomised controlled study. Turk J Anaesthesiol Reanim. 2020;48:364–370. 5 10.5152/TJAR.2019.67689
   PubMed Web of Science ®Google Scholar
• Fang B, Wang Z, Huang X Ultrasound-guided preoperative single-dose erector spinae plane block provides comparable analgesia to thoracic paravertebral block following thoracotomy: a single center randomized controlled double-blind study. Ann Transl Med. 2019;7:174. 8 10.21037/atm.2019.03.53
   PubMed Web of Science ®Google Scholar
• Pourkashanian A, Narayanan M, Venkataraju A The erector spinae plane block: a review of current evidence. Update In Anaesthesia. 2020;35:27–33.
   Google Scholar
• Forero M, Rajarathinam M, Adhikary S, et al. Erector spinae plane (ESP) block in the management of post thoracotomy pain syndrome: a case series. Scand J Pain. 2017;17(1):325–9. doi: 10.1016/j.sjpain.2017.08.013
   PubMedGoogle Scholar
• Forero M, Adhikary SD, Lopez H, et al. The erector spinae plane block: a novel analgesic technique in thoracic Neuropathic Pain. Reg Anesth Pain Med. 2016;41(5):621–7. doi: 10.1097/AAP.0000000000000451
   PubMed Web of Science ®Google Scholar
• Ibrahim M, Elnabtity AM Analgesic efficacy of erector spinae plane block in percutaneous nephrolithotomy: a randomized controlled trial. Anaesthesist. 2019;68:755–761. 11 10.1007/s00101-019-00673-w
   PubMed Web of Science ®Google Scholar
• Hamed MA, Fargaly OS, Abdelghaffar RA, et al. The role of dexmedetomidine as an adjuvant for high-thoracic erector spinae plane block for analgesia in shoulder arthroscopy; a randomized controlled study. BMC Anesthesiol. 2023;23(1):53. doi: 10.1186/s12871-023-02014-2
   PubMedGoogle Scholar
• Mohta M, Kalra B, Sethi AK, et al. Efficacy of dexmedetomidine as an adjuvant in paravertebral block in breast cancer surgery. J Anesth. 2016;30(2):252–60. doi: 10.1007/s00540-015-2123-8
   PubMed Web of Science ®Google Scholar
• Wang X, Ran G, Chen X, et al. The effect of ultrasound-guided erector spinae plane block combined with dexmedetomidine on postoperative analgesia in patients undergoing modified radical mastectomy: a randomized controlled trial. Pain Ther. 2021;10(1):475–84. doi: 10.1007/s40122-020-00234-9
   PubMed Web of Science ®Google Scholar
• Wu Y, Kang Y, Li Y, et al. Impact of ultrasound-guided deep serratus anterior plane block combined with Dexmedetomidine as an adjuvant to ropivacaine inpatient quality of recovery scores undergoing modified radical mastectomy: a randomized controlled trial. Front Oncol. 2022;12:858030. doi: 10.3389/fonc.2022.858030
   PubMed Web of Science ®Google Scholar
• Abdelhamid BM, Samy S, Abdalla A, et al. Ketamine versus neostigmine as adjuvants to bupivacaine during ultrasound-guided serratus anterior plane block in modified radical mastectomy. A randomized controlled trial. Egypt J Anaesth. 2021;37(1):356–63. doi: 10.1080/11101849.2021.1959257
   Web of Science ®Google Scholar
• Taraneh R, Alireza K, Bijan Y, et al. Efficacy of dexmedetomidine and ketamine addition to bupivacaine 0.25% by epidural method in reducing postoperative pain in patients undergoing femur fracture surgery. J Family Med Prim Care. 2021; 10(2): 832–837. 10.4103/jfmpc.jfmpc_1506_20
   PubMedGoogle Scholar
• Hassan ME, Abdelgalil AS Efficacy of dexmedetomidine as an adjuvant in erector spinae plane block in breast cancer surgery: a randomized controlled trial. Anaesth Pain Intensive Care. 2023;27:16–22. 1 10.35975/apic.v27i1.2109
   Web of Science ®Google Scholar
• Yu L, Shen X, Liu H. The effect and safety of dexmedetomidine as an adjuvant to local anesthetics in erector spinae plane block: a systematic review and meta-analysis of randomized controlled trials. BMC Anesthesiol. 2023;23(1):61. doi: 10.1186/s12871-023-02019-x
   PubMed Web of Science ®Google Scholar
• Mamta S, Nitin S, Pradeep J, et al. Role of epidural ketamine for postoperative analgesia after upper abdominal surgery. Indian J Anaesth. 2011 Mar-Apr;55(2):141–145. doi: 10.4103/0019-5049.79894
   PubMedGoogle Scholar
• Omar AM, Mansour MA, Abdelwahab HH, et al. Role of ketamine and tramadol as adjuncts to bupivacaine 0.5% in paravertebral block for breast surgery: a randomized double-blind study. Egypt J Anaesth. 2011;27(2):101–5. doi: 10.1016/j.egja.2011.04.002
   Google Scholar
• Othman AH, AM E-R, El Sherif F Efficacy and Safety of Ketamine Added to local anesthetic in modified pectoral block for management of postoperative pain in patients undergoing modified radical mastectomy. Pain Physician. 2016;19:485–494. 7;9 10.36076/ppj/2016.19.485
   PubMed Web of Science ®Google Scholar
• El Sherif FA, Youssef HA, Fares KM, et al. Efficacy of ketamine versus Magnesium Sulphate as adjuvants to levobupivacaine in ultrasound bilevel erector spinae block in breast cancer surgery (a Double-Blinded Randomized Controlled Study). Local Reg Anesth. 2022;15:87–96. doi: 10.2147/LRA.S379194
   PubMed Web of Science ®Google Scholar
• Rahimzadeh P, Faiz SH, Ziyaeifard M, et al. Effectiveness of adding ketamine to ropivacaine infusion via femoral nerve catheter after knee anterior cruciate ligament repair. J Res Med Sci. 2013;18:632–636. 8
   PubMed Web of Science ®Google Scholar