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Anticancer Original Research Papers

CircAGFG1 absence decreases PKM2 expression to enhance oxaliplatin sensitivity in colorectal cancer in a miR-7-5p-dependent manner

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Pages 208-221 | Received 30 Mar 2023, Accepted 28 Aug 2023, Published online: 10 Sep 2023

References

  • Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. doi: 10.3322/caac.21492.
  • Mármol I, Sánchez-de-Diego C, Pradilla Dieste A, et al. Colorectal carcinoma: a general overview and future perspectives in colorectal cancer. Int J Mol Sci. 2017;18(1):197.
  • Brody H. Colorectal cancer. Nature. 2015;521(7551):S1–S1. doi: 10.1038/521S1a.
  • Chen G, Gong T, Wang Z, et al. Colorectal cancer organoid models uncover oxaliplatin-resistant mechanisms at single cell resolution. Cell Oncol. 2022;45(6):1169–1170. doi: 10.1007/s13402-022-00728-y.
  • Alberts SR, Horvath WL, Sternfeld WC, et al. Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer: a north central cancer treatment group phase II study. J Clin Oncol. 2005;23(36):9243–9249. doi: 10.1200/JCO.2005.07.740.
  • Shen X, Zhang Y, Xu Z, et al. KLF5 inhibition overcomes oxaliplatin resistance in patient-derived colorectal cancer organoids by restoring apoptotic response. Cell Death Dis. 2022;13(4):303. doi: 10.1038/s41419-022-04773-1.
  • Chen S, Huang V, Xu X, et al. Widespread and functional RNA circularization in localized prostate cancer. Cell. 2019;176(4):831–843.e22. doi: 10.1016/j.cell.2019.01.025.
  • Wang Y, Liu J, Ma J, et al. Exosomal circRNAs: biogenesis, effect and application in human diseases. Mol Cancer. 2019;18(1):116. doi: 10.1186/s12943-019-1041-z.
  • Ju J, Song YN, Chen XZ, et al. circRNA is a potential target for cardiovascular diseases treatment. Mol Cell Biochem. 2022;477(2):417–430. doi: 10.1007/s11010-021-04286-z.
  • Chen L, Song Y, Hou T, et al. Circ_0004087 interaction with SND1 promotes docetaxel resistance in prostate cancer by boosting the mitosis error correction mechanism. J Exp Clin Cancer Res. 2022;41(1):194. doi: 10.1186/s13046-022-02404-3.
  • Li X, Wang N, Leng H, et al. Hsa_circ_0043949 reinforces temozolomide resistance via upregulating oncogene ITGA1 axis in glioblastoma. Metab Brain Dis. 2022;37(8):2979–2993. doi: 10.1007/s11011-022-01069-3.
  • Qiu X, Xu Q, Liao B, et al. Circ-CCS regulates oxaliplatin resistance via targeting miR-874-3p/HK2 axis in colorectal cancer. Histol Histopathol. 2022:18565. Online ahead of print. doi: 10.14670/HH-18-565.
  • Li T, Xing G, Lu L, et al. CircAGFG1 promotes osteosarcoma progression and stemness by competing with miR-302a-3p to upregulate the expression of LATS2. Evid Based Complement Alternat Med. 2022;2022:6370766. doi: 10.1155/2022/6370766.
  • Wang XH, Li J. CircAGFG1 aggravates the progression of cervical cancer by downregulating p53. Eur Rev Med Pharmacol Sci. 2020;24(4):1704–1711.
  • Xue YB, Ding MQ, Xue L, et al. CircAGFG1 sponges miR-203 to promote EMT and metastasis of non-small-cell lung cancer by upregulating ZNF281 expression. Thorac Cancer. 2019;10(8):1692–1701. doi: 10.1111/1759-7714.13131.
  • Zhang L, Dong X, Yan B, et al. CircAGFG1 drives metastasis and stemness in colorectal cancer by modulating YY1/CTNNB1. Cell Death Dis. 2020;11(7):542. doi: 10.1038/s41419-020-2707-6.
  • Ferruelo A, Peñuelas Ó, Lorente JA. MicroRNAs as biomarkers of acute lung injury. Ann Transl Med. 2018;6(2):34–34. doi: 10.21037/atm.2018.01.10.
  • Kim J, Yao F, Xiao Z, et al. MicroRNAs and metastasis: small RNAs play big roles. Cancer Metastasis Rev. 2018;37(1):5–15. doi: 10.1007/s10555-017-9712-y.
  • Ning T, Li J, He Y, et al. Exosomal miR-208b related with oxaliplatin resistance promotes Treg expansion in colorectal cancer. Mol Ther. 2021;29(9):2723–2736. doi: 10.1016/j.ymthe.2021.04.028.
  • Zhao B, Wang Y, Zhao X, et al. SIRT1 enhances oxaliplatin resistance in colorectal cancer through microRNA-20b-3p/DEPDC1 axis. Cell Biol Int. 2022;46(12):2107–2117. doi: 10.1002/cbin.11905.
  • Tanaka S, Hosokawa M, Miyamoto T, et al. miR-33a-5p in small extracellular vesicles as non-invasive biomarker for oxaliplatin sensitivity in human colorectal cancer cells. Biochem Biophys Rep. 2021;26:100996. doi: 10.1016/j.bbrep.2021.100996.
  • Liang Z-Z, Guo C, Zou M-M, et al. circRNA-miRNA-mRNA regulatory network in human lung cancer: an update. Cancer Cell Int. 2020;20(1):173–173. doi: 10.1186/s12935-020-01245-4.
  • Yi Y, Liu Y, Wu W, et al. Reconstruction and analysis of circRNA‑miRNA‑mRNA network in the pathology of cervical cancer. Oncol Rep. 2019;41(4):2209–2225. doi: 10.3892/or.2019.7028.
  • Dong M, Xie Y, Xu Y. miR-7-5p regulates the proliferation and migration of colorectal cancer cells by negatively regulating the expression of Krüppel-like factor 4. Oncol Lett. 2019;17(3):3241–3246. doi: 10.3892/ol.2019.10001.
  • Li Y, Li X, Liu J, et al. PKM2, a potential target for regulating cancer. Gene. 2018;668:48–53. doi: 10.1016/j.gene.2018.05.038.
  • Yin C, Lu W, Ma M, et al. Efficacy and mechanism of combination of oxaliplatin with PKM2 knockdown in colorectal cancer. Oncol Lett. 2020;20(6):312–311. doi: 10.3892/ol.2020.12175.
  • Cao F, Yang D, Tang F, et al. Girdin promotes tumorigenesis and chemoresistance in lung adenocarcinoma by interacting with PKM2. Cancers. 2022;14(22):5688. doi: 10.3390/cancers14225688.
  • Wang Y, Hao F, Nan Y, et al. PKM2 inhibitor Shikonin overcomes the cisplatin resistance in bladder cancer by inducing necroptosis. Int J Biol Sci. 2018;14(13):1883–1891. doi: 10.7150/ijbs.27854.
  • Eisenhauer EA, Therasse P, Bogaerts J, et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer. 2009;45(2):228–247. doi: 10.1016/j.ejca.2008.10.026.
  • Ding C, Yi X, Wu X, et al. Exosome-mediated transfer of circRNA CircNFIX enhances temozolomide resistance in glioma. Cancer Lett. 2020;479:1–12. doi: 10.1016/j.canlet.2020.03.002.
  • Peng QS, Cheng YN, Zhang WB, et al. circRNA_0000140 suppresses oral squamous cell carcinoma growth and metastasis by targeting miR-31 to inhibit hippo signaling pathway. Cell Death Dis. 2020;11(2):112. doi: 10.1038/s41419-020-2273-y.
  • Jian X, He H, Zhu J, et al. Hsa_circ_001680 affects the proliferation and migration of CRC and mediates its chemoresistance by regulating BMI1 through miR-340. Mol Cancer. 2020;19(1):20–20. doi: 10.1186/s12943-020-1134-8.
  • Pan Z, Zheng J, Zhang J, et al. A novel protein encoded by exosomal CircATG4B induces oxaliplatin resistance in colorectal cancer by promoting autophagy. Adv Sci. 2022;9(35):e2204513.
  • Xu Y, Qiu A, Peng F, et al. Exosomal transfer of circular RNA FBXW7 ameliorates the chemoresistance to oxaliplatin in colorectal cancer by sponging miR-18b-5p. Neoplasma. 2021;68(1):108–118. doi: 10.4149/neo_2020_200417N414.
  • Yang R, Xing L, Zheng X, et al. The circRNA circAGFG1 acts as a sponge of miR-195-5p to promote triple-negative breast cancer progression through regulating CCNE1 expression. Mol Cancer. 2019;18(1):4. doi: 10.1186/s12943-018-0933-7.
  • Ma X, Wang C, Chen J, et al. circAGFG1 sponges miR-28-5p to promote non-small-cell lung cancer progression through modulating HIF-1α level. Open Med. 2021;16(1):703–717. doi: 10.1515/med-2021-0269.
  • Green DR, Evan GI. A matter of life and death. Cancer Cell. 2002;1(1):19–30. doi: 10.1016/s1535-6108(02)00024-7.
  • Vardiyan R, Ezati D, Anvari M, et al. Effect of L-carnitine on the expression of the apoptotic genes Bcl-2 and Bax. Clin Exp Reprod Med. 2020;47(3):155–160. doi: 10.5653/cerm.2019.03440.
  • Nguyen T, Le A. Glucose metabolism in cancer. Adv Exp Med Biol. 2018;1063:107–118.
  • Zhao J, Li J, Hassan W, et al. Sam68 promotes aerobic glycolysis in colorectal cancer by regulating PKM2 alternative splicing. Ann Transl Med. 2020;8(7):459–459. doi: 10.21037/atm.2020.03.108.
  • Fu R, Yang P, Amin S, et al. A novel miR-206/hnRNPA1/PKM2 axis reshapes the Warburg effect to suppress colon cancer growth. Biochem Biophys Res Commun. 2020;531(4):465–471. doi: 10.1016/j.bbrc.2020.08.019.
  • Lu WQ, Hu YY, Lin XP, et al. Knockdown of PKM2 and GLS1 expression can significantly reverse oxaliplatin-resistance in colorectal cancer cells. Oncotarget. 2017;8(27):44171–44185. doi: 10.18632/oncotarget.17396.
  • Wang X, Zhang H, Yang H, et al. Exosome-delivered circRNA promotes glycolysis to induce chemoresistance through the miR-122-PKM2 axis in colorectal cancer. Mol Oncol. 2020;14(3):539–555. doi: 10.1002/1878-0261.12629.
  • Zheng W, Li H, Zhang H, et al. Long noncoding RNA RHPN1-AS1 promotes colorectal cancer progression via targeting miR-7-5p/OGT axis. Cancer Cell Int. 2020;20(1):54. doi: 10.1186/s12935-020-1110-9.

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