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Antimicrobial Original Research Papers

Effectiveness and safety of a disposable elastomeric continuous infusion pump for outpatient parenteral antimicrobial therapy (OPAT) in a UK setting

ORCID Icon, ORCID Icon & ORCID Icon
Pages 119-126 | Received 09 Jun 2023, Accepted 26 Oct 2023, Published online: 09 Nov 2023

References

  • Bryant PA, Katz NT. Inpatient versus outpatient parenteral antibiotic therapy at home for acute infections in children: a systematic review. Lancet Infect Dis. 2018;18(2):e45–e54. doi: 10.1016/S1473-3099(17)30345-6.
  • Durojaiye OC, Bell H, Andrews D, et al. Clinical efficacy, cost analysis and patient acceptability of outpatient parenteral antibiotic therapy (OPAT): a decade of sheffield (UK) OPAT service. Int J Antimicrob Agent. 2018;51(1):26–32. doi: 10.1016/j.ijantimicag.2017.03.016.
  • Mitchell ED, Czoski Murray C, Meads D, et al. Clinical and cost-effectiveness, safety and acceptability of community intravenous antibiotic service models: CIVAS systematic review. BMJ Open. 2017;7(4):e013560. doi: 10.1136/bmjopen-2016-013560.
  • Douiyeb S, de la Court JR, Tuinte B, et al. Risk factors for readmission among patients receiving outpatient parenteral antimicrobial therapy: a retrospective cohort study. Int J Clin Pharm. 2022;44(2):557–563. doi: 10.1007/s11096-022-01379-7.
  • Durojaiye OC, Morgan R, Chelaghma N, et al. External validity and clinical usefulness of a risk prediction model for 30 day unplanned hospitalization in patients receiving outpatient parenteral antimicrobial therapy. J Antimicrob Chemother. 2021;76(8):2204–2212. doi: 10.1093/jac/dkab127.
  • Chapman ALN, Patel S, Horner C, et al. Updated good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults and children in the UK. JAC Antimicrob Resist. 2019;1:dlz026.
  • Diamantis S, Dawudi Y, Cassard B, et al. Home intravenous antibiotherapy and the proper use of elastomeric pumps: systematic review of the literature and proposals for improved use. Infect Dis Now. 2021;51(1):39–49. doi: 10.1016/j.medmal.2020.10.019.
  • Voumard R, Gardiol C, André P, et al. Efficacy and safety of continuous infusions with elastomeric pumps for outpatient parenteral antimicrobial therapy (OPAT): an observational study. J Antimicrob Chemother. 2018;73(9):2540–2545. doi: 10.1093/jac/dky224.
  • Karimaghaei S, Rao A, Chijioke J, et al. Characteristics, safety and cost-effectiveness analysis of self-administered outpatient parenteral antibiotic therapy via a disposable elastomeric continuous infusion pump at two county hospitals in Houston, Texas, United States. J Clin Pharm Ther. 2022;47(2):211–217. doi: 10.1111/jcpt.13550.
  • Allwood MC, Stonkute D, Wallace A, et al. Assessment of the stability of citrate-buffered flucloxacillin for injection when stored in two commercially available ambulatory elastomeric devices: INfusor LV (baxter) and accufuser (Woo Young Medical): a study compliant with the NHS yellow cover document (YCD) requirements. Eur J Hosp Pharm. 2020;27(2):90–94. doi: 10.1136/ejhpharm-2018-001515.
  • Jamieson C, Ozolina L, Seaton RA, et al. Assessment of the stability of citrate-buffered piperacillin/tazobactam for continuous infusion when stored in two commercially available elastomeric devices for outpatient parenteral antimicrobial chemotherapy: a study compliant with the NHS yellow cover document requirements. Eur J Hosp Pharm. 2022;29(4):212–216. doi: 10.1136/ejhpharm-2020-002340.
  • Oliver G. Optimising patient safety when using elastomeric pumps to administer outpatient parenteral antibiotic therapy. Br J Nurs. 2016;25(19):S22–S27. doi: 10.12968/bjon.2016.25.19.S22.
  • Zhang Y, Ody YC, Davis L. Clinical effectiveness of flucloxacillin delivery using an elastomeric device for outpatient parenteral antimicrobial therapy. Br J Community Nurs. 2020;25(8):376–380. doi: 10.12968/bjcn.2020.25.8.376.
  • Durojaiye OC, Jibril I, Kritsotakis EI. Palliative outpatient parenteral antimicrobial therapy (OPAT): a single center experience and systemic scoping review. A systematic review. Clin Infect Pract. 2022;16:100205. doi: 10.1016/j.clinpr.2022.100205.
  • Durojaiye OC, Slucka A, Kritsotakis EI. Retrospective analysis of outcomes of outpatient parenteral antimicrobial therapy (OPAT) for necrotising otitis externa. Eur J Clin Microbiol Infect Dis. 2022;41(6):941–949. doi: 10.1007/s10096-022-04455-y.
  • British Society for Antimicrobial Chemotherapy (BSAC). The British society for antimicrobial chemotherapy outpatient parenteral antimicrobial therapy national outcomes registry system (NORS) user guide. BSAC, Birmingham, UK, 2018. https://e-opat.com/wp-content/uploads/2018/12/NORS-UserGuide-141218.pdf
  • Ganapathy S, Amendola A, Lichfield R, et al. Elastomeric pumps for ambulatory patient controlled regional analgesia. Can J Anaesth. 2000;47(9):897–902. doi: 10.1007/BF03019672.
  • Schöffski P, Cerbone L, Wolter P, et al. Administration of 24-h intravenous infusions of trabectedin in ambulatory patients with mesenchymal tumors via disposable elastomeric pumps: an effective and patient-friendly palliative treatment option. Onkologie. 2012;35(1-2):14–17. doi: 10.1159/000335879.
  • Pandya KH, Eaton V, Kowalski S, et al. Safety of continuous antibiotic infusions administered through an Australian hospital in the home service: a pilot study. Pharm Pract Res. 2017;47(5):333–339. doi: 10.1002/jppr.1291.
  • Ferreiro JLL, Otero JÁ, Rivo AS, et al. Outpatient therapy with piperacillin/tazobactam using elastomeric pumps in patients with Pseudomonas aeruginosa infection. Sci Rep. 2021;11(1):8610. doi: 10.1038/s41598-021-88179-7.
  • García-Queiruga M, Feal Cortizas B, Lamelo Alfonsín F, et al. Continuous infusion of antibiotics using elastomeric pumps in the hospital at home setting. Rev Esp Quimioter. 2021;34(3):200–206. doi: 10.37201/req/122.2020.
  • Manning L, Wright C, Ingram PR, et al. Continuous infusions of meropenem in ambulatory care: clinical efficacy, safety and stability. PLoS One. 2014;9(7):e102023. doi: 10.1371/journal.pone.0102023.
  • Dubois-Silva Á, Otero-Plaza L, Dopico-Santamariña L, et al. Outpatient parenteral antimicrobial therapy with continuous infusion of meropenem: a retrospective analysis of three years of clinical experience. Enferm Infecc Microbiol. Clin (Engl Ed). 2023; 41(6):321-328. doi: 10.1016/j.eimce.2021.11.012.
  • Arensdorff L, Boillat-Blanco N, Decosterd L, et al. Adequate plasma drug concentrations suggest that amoxicillin can be administered by continuous infusion using elastomeric pumps. J Antimicrob Chemother. 2017;72(9):2613–2615. doi: 10.1093/jac/dkx178.
  • Barr DA, Semple L, Seaton RA. Self-administration of outpatient parenteral antibiotic therapy and risk of catheter-related adverse events: a retrospective cohort study. Eur J Clin Microbiol Infect Dis. 2012;31(10):2611–2619. doi: 10.1007/s10096-012-1604-z.
  • Bodycot J, Mashonganyika L, Kucziw N, et al. Maximising the opportunity of a self-administration outpatient parenteral antimicrobial therapy pathway. Br J Nurs. 2021;30(2):S4–S10. doi: 10.12968/bjon.2021.30.2.S4.
  • Matthews PC, Conlon CP, Berendt AR, et al. Outpatient parenteral antimicrobial therapy (OPAT): is it safe for selected patients to self-administer at home? A retrospective analysis of a large cohort over 13 years. J Antimicrob Chemother. 2007;60(2):356–362. doi: 10.1093/jac/dkm210.
  • Durojaiye OC, Jibril I, Kritsotakis EI. Effectiveness of telemedicine in outpatient parenteral antimicrobial therapy (Tele-OPAT): a systematic review. J Telemed Telecare. 2022;0(0):1357633X221131842. doi: 10.1177/1357633X221131842.
  • Saillen L, Arensdorff L, Moulin E, et al. Patient satisfaction in an outpatient parenteral antimicrobial therapy (OPAT) unit practising predominantly self-administration of antibiotics with elastomeric pumps. Eur J Clin Microbiol Infect Dis. 2017;36(8):1387–1392. doi: 10.1007/s10096-017-2944-5.
  • Jenkins A, Shanu S, Jamieson C, et al. Widening the net: a literature review of antimicrobial agents with potential suitability for outpatient parenteral antimicrobial therapy services – the importance of storage and stability. Eur J Hosp Pharm. 2023;30(2):64–69. doi: 10.1136/ejhpharm-2021-002937.
  • Jones TE, Selby PR, Mellor CS, et al. Ceftazidime stability and pyridine toxicity during continuous i.v. infusion. Am J Health Syst Pharm. 2019;76(4):200–205. doi: 10.1093/ajhp/zxy035.
  • Jenkins A, Hills T, Santillo M, et al. Extended stability of antimicrobial agents in administration devices. J Antimicrob Chemother. 2017;72(4):1217–1220. doi: 10.1093/jac/dkw556.
  • Jenkins A, Shanu S, Jamieson C, et al. Systematic review of the stability of antimicrobial agents in elastomeric devices for outpatient parenteral antimicrobial therapy services based on NHS yellow cover document standards. Eur J Hosp Pharm. 2022;29(6):304–307. doi: 10.1136/ejhpharm-2021-002729.
  • Sime FB, Wallis S, Jamieson C, et al. Evaluation of the stability of temocillin in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy in accordance with the requirements of the UK NHS yellow cover document. Eur J Hosp Pharm. 2023;30(e1):e76–e81. ejhpharm-2022-003286.
  • Jamieson C, Allwood MC, Stonkute D, et al. Investigation of meropenem stability after reconstitution: the influence of buffering and challenges to meet the NHS yellow cover document compliance for continuous infusions in an outpatient setting. Eur J Hosp Pharm. 2020;27(e1):e53–e57. doi: 10.1136/ejhpharm-2018-001699.
  • Lui GY, Dickson HG, West D, et al. Elastomeric pump infusion failures caused by inadequate luer lock connector engagement to needleless connectors. J Infus Nurs. 2021;44(5):274–281. doi: 10.1097/NAN.0000000000000439.
  • Mizuuchi M, Yamakage M, Iwasaki S, et al. The infusion rate of most disposable, non-electric infusion pumps decreases under hypobaric conditions. Can J Anaesth. 2003;50(7):657–662. doi: 10.1007/BF03018707.

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