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Expert Opinion on Investigational Drugs Volume 27, 2018 - Issue 3
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Editorial

Inhaled medication therapy for bronchiectasis: status quo and the next frontier

Chun-lan ChenState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, ChinaView further author information
,
Yan HuangState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, ChinaView further author information
,
Yong-hua GaoFirst Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaView further author information
,
Rong-chang ChenState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, ChinaView further author information
,
Nan-shan ZhongState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, ChinaView further author information
&
Wei-jie GuanState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China;Sino-French Hoffmann Institute, Guangzhou Medical University, Guangzhou, ChinaCorrespondence[email protected]
View further author information
Pages 211-218 | Received 25 Sep 2017, Accepted 08 Feb 2018, Published online: 15 Feb 2018

References

  • Cole PJ. Inflammation: a two-edged sword– the model of bronchiectasis. Eur J Respir Dis Suppl. 1986;147:6–15.
  • Quint JK, Millett ER, Joshi M, et al. Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013: a population-based cohort study. Eur Respir J. 2016;47:186–193.
  • Ringshausen FC, de Roux A, Diel R, et al. Bronchiectasis in Germany: a population-based estimation of disease prevalence. Eur Respir J. 2015;46:1805–1807.
  • Pasteur MC, Bilton D, Hill AT. British thoracic society bronchiectasis non-CF guideline group. British thoracic society guideline for non-CF bronchiectasis. Thorax. 2010;65(Sppul1):i1–58.
  • Polverino E, Goeminne PC, McDonnell MJ, et al. European respiratory society guidelines for the management of adult bronchiectasis. Eur Respir J. 2017;50(3). pii:1700629.
  • Antoniu SA. Investigational inhaled therapies for non-CF bronchiectasis. Exp Opin Invest Drug. 2018 Jan 25;2:1–8.
  • Hewitt WL. Antibiotic therapy of abscess of the lung and bronchiectasis. Calif Med. 1952;76:319–324.
  • O’Donnell AE, Barker AF, Ilowite JS, et al. Treatment of idiopathic bronchiectasis with aerosolized recombinant human DNase I. rhDNase Study Group. Chest. 1998;113:1329–1334.
  • Chalmers JD, Smith MP, McHugh BJ, et al. Short- and long-term antibiotic treatment reduces airway and systemic inflammation in non-cystic fibrosis bronchiectasis. Am J Respir Crit Care Med. 2012;186:657–665.
  • Hnin K, Nguyen C, Carson KV, et al. Prolonged antibiotics for non-cystic fibrosis bronchiectasis in children and adults. Cochrane Database Syst Rev. 2015;13:CD001392.
  • Tarrant BJ, Le Maitre C, Romero L, et al. Mucoactive agents for chronic, non-cystic fibrosis lung disease: a systematic review and meta-analysis. Respirology. 2017;22:1084–1092.
  • Goyal V, Chang AB. Combination inhaled corticosteroids and long-acting beta2-agonists for children and adults with bronchiectasis. Cochrane Database Syst Rev. 2014;6:CD010327.
  • Ohta S. Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications. Methods Enzymol. 2015;555:289–317.
  • Guan WJ, Gao YH, Xu G, et al. Effect of airway Pseudomonas aeruginosa isolation and infection on steady-state bronchiectasis in Guangzhou, China. J Thorac Dis. 2015;7:625–636.

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