Optimizing quality of life through sex steroids by their effects on neurotransmitters

References

• Del Río JP, Alliende MI, Molina N, et al. Steroid hormones and their action in Women's Brains: the Importance of Hormonal Balance. Front Public Health 2018;6:141
   PubMed Web of Science ®Google Scholar
• Pluchino N, Santoro A, Casarosa E, et al. Advances in neurosteroids: role in clinical practice. Climacteric 2013;16:8–17
   PubMed Web of Science ®Google Scholar
• Morris RGM, Anderson E, Lynch GS, Baudry M. Selective impairment of learning and blockade of long-term potentiation by an N-methylD-aspartate receptor antagonist, AP5. Nature 1986;319:774–6
   PubMed Web of Science ®Google Scholar
• Adams MM, Fink SE, Janssen WGM, Shah RA, Morrison JH. Estrogen modulates synaptic N-methyl-D-aspartate receptor subunit distribution in the aged hippocampus. J Comp Neurol 2004;474:419–26
   PubMed Web of Science ®Google Scholar
• Mukherjee J, Cardarelli RA, Cantaut-Belarif Y, et al. Estradiol modulates the efficacy of synaptic inhibition by decreasing the dwell time of GABA A receptors at inhibitory synapses. Proc Natl Acad Sci U S A 2017;114:11763–8
   PubMed Web of Science ®Google Scholar
• Hiroi R, Neumaier JF. Estrogen decreases 5-HT1B autoreceptor mRNA in selective subregion of rat dorsal raphe nucleus: inverse association between gene expression and anxiety behavior in the open field. Neuroscience 2009;158:456–64
   PubMed Web of Science ®Google Scholar
• Jacobs E, D’Esposito M. Estrogen shapes dopamine-dependent cognitive processes: implications for women’s health. J Neurosci 2011;31:5286–93
   PubMed Web of Science ®Google Scholar
• Nicola SM. The nucleus accumbens as part of a basal ganglia action selection circuit. Psychopharmacology (Berl) 2007;191:521–50
   PubMed Web of Science ®Google Scholar
• Feng XQ, Dong Y, Fu YM, et al. Progesterone inhibition of dopamine-induced increase in frequency of spontaneous excitatory postsynaptic currents in rat prelimbic cortical neurons. Neuropharmacology 2004;46:211–22
   PubMed Web of Science ®Google Scholar
• Deligiannidis KM, Sikoglu EM, Shaffer SA, et al. GABAergic neuroactive steroids and restingstate functional connectivity in postpartum depression: a preliminary study. J Psychiatr Res 2013;47:816–28
   PubMed Web of Science ®Google Scholar
• Smith SS. Withdrawal properties of a neuroactive steroid: implications for GABAA receptor gene regulation in the brain and anxiety behavior. Steroids 2002;67:519–28
   PubMed Web of Science ®Google Scholar
• Yen JY, Chang SJ, Long CY, et al. Working memory deficit in premenstrual dysphoric disorder and its associations with difficulty in concentrating and irritability. Compr Psychiatry 2012;53:540–5
   PubMed Web of Science ®Google Scholar
• Frye CA, Sora I. Progesterone reduces hyperactivity of female and male dopamine transporter knockout mice. Behav Brain Res 2010;209:59–65
   PubMed Web of Science ®Google Scholar
• Dazzi L, Serra M, Vacca G, et al. Depletion of cortical allopregnanolone potentiates stress-induced increase in cortical dopamine output. Brain Res 2002;932:135–9
   PubMed Web of Science ®Google Scholar
• Zheng P. Neuroactive steroid regulation of neurotransmitter release in the CNS: action, mechanism and possible significance. Prog Neurobiol 2009;89:134–52
   PubMed Web of Science ®Google Scholar
• Goodnick PJ, Chaudry T, Artadi J, Arcey S. Women' s issues in mood disorders. Expert Opin Pharmacother 2000;1:903–16
   PubMedGoogle Scholar
• Wharton W, Gleason CE, Olson SR, Carlsson CM, Asthana S. Neurobiological underpinnings of the estrogen – mood relationship. Curr Psychiatry Rev 2013;8:247–56
   Google Scholar
• Raz L, Hunte LV, Dowling NM, et al. Differential effects of hormone therapy on serotonin, vascular function and mood in the KEEPS. Climacteric 2016;19:49–59
   PubMed Web of Science ®Google Scholar
• Vanhoutte PM, Luscher TF. Serotonin and the blood vessel wall. J Hypertens Suppl 1986;4:S29–S35
   PubMedGoogle Scholar
• Greendale GA, Derby CA, Maki PM. Perimenopause and cognition. Obstet Gynecol Clin North Am 2011;38:519–35
   PubMed Web of Science ®Google Scholar
• Gleason CE, Carlsson CM, Johnson S, Atwood C, Asthana S. Clinical pharmacology and differential cognitive efficacy of estrogen preparations. Ann N Y Acad Sci 2005;115:93–115
   Google Scholar
• Frey BN, Lord C, Soares CN. Depression during menopausal transition: a review of treatment strategies and pathophysiological correlates. Menopause Int 2008;14:123–8
   PubMedGoogle Scholar
• Halbreich U, Kahn LS. Role of estrogen in the aetiology and treatment of mood disorders. CNS Drugs 2001;15:797–817
   PubMed Web of Science ®Google Scholar
• Shumaker SA, Legault C, Rapp SR, et al. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. JAMA 2003;289:2651–62
   PubMed Web of Science ®Google Scholar
• Rapp SR, Espeland MA, Shumaker SA, et al. Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. JAMA 2003;289:2663–72
   PubMed Web of Science ®Google Scholar
• Reddy DS. Neurosteroids: endogenous role in the human brain and therapeutic potentials. Prog Brain Res 2010;186:113–37
   PubMed Web of Science ®Google Scholar
• Moraga-Amaro R, van Waarde A, Doorduin J, de Vries EFJ. Sex steroid hormones and brain function: PET imaging as a tool for research. J Neuroendocrinol 2018;30:e12565
   Web of Science ®Google Scholar
• Laumann E, Paik A, Rosen RC. Sexual dysfunction in the United States: prevalence and predictors. JAMA 1999;281:537–44
   PubMed Web of Science ®Google Scholar
• Davis S, Davison SL, Donath S, Bell RJ. Circulating androgen levels and self-reported sexual function in women. JAMA 2005;294:91–6
   PubMed Web of Science ®Google Scholar
• Labrie F, Luu-The V, Labrie C, et al. Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Endocr Rev 2003;24:152–82
   PubMed Web of Science ®Google Scholar