123
Views
0
CrossRef citations to date
0
Altmetric
Special Report

Decoding treatment efficacy: uncovering response and failure dynamics to biologics in asthma

ORCID Icon
Pages 25-29 | Received 02 Nov 2023, Accepted 03 Jan 2024, Published online: 05 Jan 2024

References

  • The global asthma network, “the global asthma report 2022”. 2022 [cited 2023 Sep 10]. [Online]. Available from: http://globalasthmareport.org/
  • World Health Organisation. WHO. Asthma. 2020 [cited 2023 Dec. 9]. Available from: https://www.who.int/news-room/facts-in-pictures/detail/asthma
  • Patel VH, Thannir S, Dhanani M, et al. Current limitations and recent advances in the management of asthma. Dis Mon. 2023 Jul;69(7):101483.
  • Bousquet J, Chiron R, Humbert M. Biologics in asthma: difficulties and drawbacks. Expert Opin Biol Ther. 2008 Dec;8(12):1921–1928. doi: 10.1517/14712590802496928
  • Patel SS, Casale TB, Cardet JC. Biological therapies for eosinophilic asthma. Expert Opin Biol Ther. 2018 Jul;18(7):747–754. doi: 10.1080/14712598.2018.1492540
  • Salter B, Lacy P, Mukherjee M. Biologics in asthma: a molecular perspective to precision medicine. Front Pharmacol. 2021;12:793409. doi: 10.3389/fphar.2021.793409
  • Scioscia G, Nolasco S, Campisi R, et al. Switching biological therapies in severe asthma. Int J Mol Sci. 2023 May;24(11):9563.
  • Parulekar AD, Diamant Z, Hanania NA. Role of T2 inflammation biomarkers in severe asthma. Curr Opin Pulm Med. 2016 Jan;22(1):59–68. doi: 10.1097/MCP.0000000000000231
  • Al Ghobain MO, Alsubaie AS, Aljumah WA, et al. The correlation between fractional exhaled nitric oxide (FeNO), blood eosinophil Count, immunoglobulin E levels, and spirometric values in patients with asthma. Cureus. 2023 Feb;15(2):e35289.
  • Sze E, Bhalla A, Nair P. Mechanisms and therapeutic strategies for non-T2 asthma. Allergy. 2020 Feb;75(2):311–325. doi: 10.1111/all.13985
  • Iftikhar IH, Schimmel M, Bender W, et al. Comparative efficacy of anti IL-4, IL-5 and IL-13 drugs for treatment of eosinophilic asthma: a network meta-analysis. Lung. 2018 Oct;196(5):517–530. doi: 10.1007/s00408-018-0151-5
  • Gon Y, Maruoka S, Mizumura K. Omalizumab and IgE in the control of severe allergic asthma. Front Pharmacol. 2022;13:839011. doi: 10.3389/fphar.2022.839011
  • López-Viña A, Díaz Campos RM, Trisan Alonso A, et al. Uncontrolled severe T2 asthma: which biological to choose? A biomarker-based approach. Front Allergy. 2022;3:1007593. doi: 10.3389/falgy.2022.1007593
  • Runnstrom M, Pitner H, Xu J, et al. Utilizing predictive inflammatory markers for guiding the use of biologicals in severe asthma. J Inflamm Res. 2022;15:241–249. doi: 10.2147/JIR.S269297
  • Nair P, Prabhavalkar KS. Neutrophilic asthma and potentially related target therapies. Curr Drug Targets. 2020;21(4):374–388. doi: 10.2174/1389450120666191011162526
  • Mukherjee M, Nair P. Autoimmune Responses in Severe Asthma. Allergy Asthma Immunol Res. 2018 Sep;10(5):428–447. doi: 10.4168/aair.2018.10.5.428
  • Campisi R, Nolasco S, Pelaia C, et al. Benralizumab effectiveness in severe eosinophilic asthma with Co-presence of Bronchiectasis: a real-world multicentre observational study. J Clin Med. 2023;12(12):3953. doi: 10.3390/jcm12123953
  • Portacci A, Dragonieri S, Carpagnano GE. Super-responders to biologic treatment in type 2-high severe asthma: passing fad or a meaningful phenotype? J Allergy Clin Immunol Pract. 2023 May;11(5):1417–1420. doi: 10.1016/j.jaip.2023.01.021
  • Gautam Y, Johansson E, Mersha TB. Multi-omics profiling approach to asthma: an evolving paradigm. J Pers Med. 2022 Jan;12(1). doi: 10.3390/jpm12010066
  • Papaioannou AI, Fouka E, Bartziokas K, et al. Defining response to therapy with biologics in severe asthma: from global evaluation to super response and remission. Expert Rev Respir Med. 2023;17(6):481–493. doi: 10.1080/17476348.2023.2226392

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.