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Case Report

The safety and effectiveness of low-level light therapy (LLLT) with light-emitting diode (LED) bed system and a novel topical anti-cellulite gel on grades 1–2 thigh/buttock cellulite: a randomized, comparative-controlled split-thigh/buttock IRB study

Pages 45-53 | Received 10 Mar 2021, Accepted 25 Jun 2021, Published online: 07 Feb 2023

References

  • Nurnberger F, Muller G. So-called cellulite: an invented disease. J Dermatol Surg Oncol. 1978;4:221–29. doi:10.1111/j.1524-4725.1978.tb00416.x.
  • Rossi AB, Vergnanini AL. Cellulite: a review. J Eur Acad Dermatol Venereol. 2000;14:251–62. doi:10.1046/j.1468-3083.2000.00016.x.
  • Terranova F, Berardesca E, Maibach H. Cellulite: nature and aetiopathogenesis. Int J Cosmet Sci. 2006;28(3):157–67. doi:10.1111/j.1467-2494.2006.00316.x.
  • Mirrashed F, Sharp JC, Krause V, Morgan J, Tomanek B. Pilot study of dermal and subcutaneous fat structures by MRI in individuals who differ in gender, BMI, and cellulite grading. Skin Res Technol. 2004;10:161–68.
  • Mirrashed F, Sharp JC, Krause V, et al. Pilot study of dermal and subcutaneous fat structures byMRI in individuals who differ in gender, BMI, and cellulite grading. Skin Res Technol. 2004;10:161-168.
  • Pierared GE, Nizet JI, Pierard-Franchimont C. Cellulite: from standing fat herniation to hypodermal stretch marks. Am J Dermatopathol. 2000;22:34–47. doi:10.1097/00000372-200002000-00007.
  • Querleux B. Magnetic resonance imaging and spectroscopy of skin and subcutis. J Cosmet Dermatol. 2004;3:156–61. doi:10.1111/j.1473-2130.2004.00118.x.
  • Scherwitz C, Braun-Falco O. So-called cellulite. J Dermatol Surg Oncol. 1978;4:230–34. doi:10.1111/j.1524-4725.1978.tb00417.x.
  • Kaminer MS, Coleman WP 3rd, Weiss RA, et al. Multicenter pivotal study of vacuum-assisted precise tissue release for the treatment of cellulite. Dermatol Surg. 2015;41:336-347.
  • Dobke MK, DiBernardo B, Thompson C. Assessment of biochemical skin properties: is cellulite skin different? Aesthet Surg J. 2002;22:260–66. doi:10.1067/maj.2002.124711.
  • De Gody JMP, de Gody ACP, Godoy MFG. Considering the hypothesis of the pathophysiology of cellulite in its treatment. Dermatol Rep. 2017;9:7352.
  • Pugliese PT. The pathogenesis of cellulite: a new concept. J Cosmet Dermatol. 2007;6:140–42. doi:10.1111/j.1473-2165.2007.00312.x.
  • Omi T, Sato S, Kawana S. Ultrastructural assessment of cellulite morphology: clues to a therapeutic strategy? Laser Ther. 2013;22:131–36. doi:10.5978/islsm.13-OR-12.
  • Turati F, Pelucchi C, Marzatico F, Ferraroni M, Decarli A, Gallus S, La Vecchia C, Galeone C. Efficacy of cosmetic products in cellulite reduction: systematic review and meta-analysis. J Eur Ada Dermatol Venereol. 2014;28:1–15.
  • Schlaudraff KU, Kiessling MC, Csaszar NB, et al. Predictability of the individual clinical outcome of extracorporeal shock wave therapy for cellulite. Clin Cosmet Investig Dermatol. 2014;7:171-183.
  • Caruso MK, Roberts AT, Bissoon L, Self KS, Guillot TS, Greenway FL. An evaluation of mesotherapy solutions for inducing lipolysis and treating cellulite. J Plast Reconstr Aesthet Surg. 2008;61:1321–24.
  • Sivagnanam G. Mesotherapy-the French connection. J Pharmacol Pharmacother. 2010;1:4–8. doi:10.4103/0976-500X.64529.
  • Lask G, Fournier N, Trelles M, Elman M, Scheflan M, Slatkine M, Naimark J, Harth Y. The utilization of nonthermal blue (405–425 nm) and near infrared (850–890 nm) light in aesthetic dermatology and surgery - a multicenter study. J Cosmet Laser Therapy. 2005;7:163–70.
  • Knobloch K, Joest B, Kramer R, et al. Cellulite and focused extracorporeal shockwave therapy for non-invasive body contouring: a randomized trial. Dermatol Ther (Heidelb). 2013;3:143-155.
  • Kaminer MS, Coleman WP 3rd, Weiss RA, Robinson DM, Coleman WP, Hornfeldt C. Multicenter pivotal study of vacuum-assisted precise tissue release for the treatment of cellulite. Dermatol Surg. 2015;41:336–47.
  • Schlaudraff KU, Kiessling MC, Csaszar NB, Schmitz C. Predictability of the individual clinical outcome of extracorporeal shock wave therapy for cellulite. Clin Cosmet Investig Dermatol. 2014;7:171–83.
  • Knobloch K, Joest B, Kramer R, Vogt PM. Cellulite and focused extracorporeal shockwave therapy for non-invasive body contouring: a randomized trial. Dermatol Ther (Heidelb). 2013;3(2):143–55. doi:10.1007/s13555-013-0039-5.
  • Peterson JD, Goldman MP. Laser, light, and energy devices for cellulite and lipodystrophy. Clin Plast Surg. 2011;38:463–474, vii. doi:10.1016/j.cps.2011.02.003.
  • Sasaki GH. Single treatment of grades II and III cellulite using minimally invasive 1,440-nm pulsed Nd: yAGlaser and side-firing fiber: an institutional review board-approved study with a 24-month follow-up period. Aesthetic Plast Surg. 2013;37:1073–89. doi:10.1007/s00266-013-0219-9.
  • DiBernardo BF, Sasaki GH, Katz BE, Hunstad JP, Petti C, Burns AJ. A multicenter study for cellulite treatment using a 1440-nm Nd: yAGwavelength laser with side-firing fiber. Aesthet Surg J. 2016;36:335–43.
  • Khan MH, Victor F, Rao B, Sadick NS. Treatment of cellulite: part II. Advances and controversies. J Am Acad Dermatol. 2010;62:373–384; quiz 385.
  • Kaminer MS, Coleman WP 3rd, Weiss RA, Robinson DM, Grossman J. A multicenter pivotal study to evaluate tissue stabilized-guided subcision using the Cellfina device for the treatment of cellulite with 3-follow-up. Dermatol Surg. 2017;43(10):1240–48. doi:10.1097/DSS.0000000000001218.
  • Ibrahim O, Haimovic A, Lee N, Kaminer MS. Efficacy using a modified technique for tissue stabilized-guided subcision for the treatment of mild-to-moderate cellulite of the buttocks and thighs. Dermatol Surg. 2018;44(10):1272–77. doi:10.1097/DSS.0000000000001542.
  • Uebel CO, Piccinini PS, Martinelli A, Aguiar DF, Ramos RFM. Cellulite: a surgical treatment approach. Aesthet Surg J. 2018;38(10):1099–114. doi:10.1093/asj/sjy028.
  • Zerni I, Sisti A, Cuomo R, Ciappi S, Russo F, Brandi C, D’Aniello C, Nisi G. Cellulite treatment: a comprehensive literature review. J Cosmet Dermatol. 2015;14:224–40.
  • Rossi AM, Katz BE. A modern approach to the treatment of cellulite. Dermatol Clin. 2014;32:51–59. doi:10.1016/j.det.2013.09.005.
  • Karu T. Primary and secondary mechanisms of action of visible near-IR radiation on cells. J Photochem Photobiol B. 1999;49:1–17. doi:10.1016/S1011-1344(98)00219-X.
  • Nestor MS, Zarraga MB, Park H. Effect of 635nm low-level laser therapy on upper arm circumference reduction: a double-blind, randomized, sham-controlled trail. J Clin Aesthet Dermatol. 2012;5:42–48.
  • Kim WS, Calderhead RG. Is light-emitting diode low level light therapy (LED-LLT) really effective? Laser Ther. 2011;20:205–15. doi:10.5978/islsm.20.205.
  • Lee SY, Park KH, Choi JW, Kwon J-K, Lee DR, Shin MS, Lee JS, You CE, Park MY. A prospective, randomized, placebo-controlled, double-blinded, and split-face clinical study on LED phototherapy for skin rejuvenation: clinical, profilometric, histologic, ultrastructural, and biochemical evaluations and comparison of three different treatment settings. J Photochem Photobiol. 2007;88:51–67.
  • Rao J, Paabo K, Goldman MP. A double-blinded, randomized trial testing the tolerability and efficacy of a novel topical agent with and without occlusion for the treatment of cellulite: a study and review of the literature. J Drugs Dermatol. 2004;3:417–25.
  • Stoneham ST, Kiviluoto T, Keso L, Ohisalo JJ. Adenosine and the regional differences in adipose tissue metabolism in women. Acta Endocrinol. 1988;118:327–31.
  • Karu T. Identification of the photoreceptors. In: Ten lectures on basic science of laser phototherapy. Grangesberg, Sweden: Prima Books AB; 2007; pp. 115-142

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