335
Views
0
CrossRef citations to date
0
Altmetric
Review Article

Combination therapy in female pattern hair loss

&
Pages 1-6 | Received 02 Nov 2022, Accepted 04 Jun 2023, Published online: 08 Jun 2023

References

  • Ramos PM, Miot HA. Female pattern hair loss: a clinical and pathophysiological review. An Bras Dermatol. 2015;90(4):529–43. doi:10.1590/abd1806-4841.20153370.
  • Chan L, Cook DK. Female pattern hair loss. AJGP. 2018;47(7):459–64. doi:10.31128/AJGP-02-18-4498.
  • Tamashunas NL, Bergfeld WF. Male and female pattern hair loss: treatable and worth treating. Cleve Clin J Med. 2021 March;88(3):173–82. doi:10.3949/ccjm.88a.20014.
  • Redler S, Messenger AG, Betz RC. Genetics and other factors in the aetiology of female pattern hair loss. Exp Dermatol. 2017;26(6):510–17. doi:10.1111/exd.13373.
  • Van Zuuren EJ, Fedorowicz Z, Schoones J. Interventions for female pattern hair loss. Cochrane Database Of Systematic Reviews. 2016;5(10):CD007628. doi:10.1002/14651858.CD007628.pub4.
  • Suchonwanit P, Iamsumang W, Rojhirunsakool S. Efficacy of topical combination of 0.25% finasteride and 3% minoxidil versus 3% minoxidil solution in female pattern hair loss: a randomized, double-blind, controlled study. Am J Clin Dermatol. 2019 Feb;20(1):147–53. doi:10.1007/s40257-018-0387-0.
  • Abdel-Raouf H, Aly UF, Medhat W, Ahmed SS, Abdel-Aziz RTA. A novel topical combination of minoxidil and spironolactone for androgenetic alopecia: clinical, histopathological, and physicochemical study. Dermatol Ther. 2021 Jan;34(1):e14678. doi:10.1111/dth.14678.
  • Dhurat R, Sukesh M, Avhad G, Dandale A, Pal A, Pund P. A randomized evaluator blinded study of effect of microneedling in androgenetic alopecia: a pilot study. Int J Trichology. 2013 Jan;5(1):6–11. doi:10.4103/0974-7753.114700.
  • Smirnova EE, Smirnova IO. Comparative Evaluation of the Clinical Efficacy of PRP-Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia. Int J Mol Sci. 2020 Sep 6;21(18):6516. doi:10.3390/ijms21186516.
  • Khattab FM, Bessar H. Accelerated hair growth by combining thread monofilament and minoxidil in female androgenetic alopecia. J Cosmet Dermatol. 2020 Jul;19(7):1738–44. doi:10.1111/jocd.13228.
  • Suchonwanit P, Rojhirunsakool S, Khunkhet S. A randomized, investigator-blinded, controlled, split-scalp study of the efficacy and safety of a 1550-nm fractional erbium-glass laser, used in combination with topical 5% minoxidil versus 5% minoxidil alone, for the treatment of androgenetic alopecia. Lasers Med Sci. 2019 Dec;34(9):1857–64. doi:10.1007/s10103-019-02783-8.
  • Liu Y, Jiang L, Liu F, Qu Q, Fan Z, Guo Z, Hu Z, Hu Z-Q. Comparison of low-level light therapy and combination therapy of 5% minoxidil in the treatment of female pattern hair loss. Lasers Med Sci. 2020;36(5):1085–93. doi:10.1007/s10103-020-03157-1.
  • Faghihi G, Mozafarpoor S, Asilian A, Mokhtari F, Esfahani AA, Bafandeh B, Nouraei S, Nilforoushzadeh MA, Hosseini SM. The effectiveness of adding low-level light therapy to minoxidil 5% solution in the treatment of patients with androgenetic alopecia. Indian J Dermatol Venereol Leprol. 2018 Sep-Oct;84(5):547–53. doi:10.4103/ijdvl.IJDVL_1156_16. PMID: 30027912.
  • Mesinkovska N, WF B. Hair: what is New in Diagnosis and Management? Dermatol Clin. 2013;31(1):119–27. doi:10.1016/j.det.2012.08.005.
  • Gupta AK, Foley KA.5% Minoxidil: treatment for female pattern hair loss. Skin Therapy Lett. 2014 Nov-Dec;19(6):5–7. PMID: 25807073.
  • Beach RA. Case series of oral minoxidil for androgenetic and traction alopecia: tolerability & the five C’s of oral therapy. Dermatol Ther. 2018 Nov;31(6):e12707. doi:10.1111/dth.12707.
  • Uzel BPC, Takano GHS, Chartuni JCN, Cesetti MV, Gavioli CFB, Lemes AM, Costa IMC. Intradermal injections with 0.5% minoxidil for the treatment of female androgenetic alopecia: a randomized, placebo-controlled trial. Dermatol Ther. 2021 Jan;34(1):e14622. doi:10.1111/dth.14622.
  • Ramos PM, Sinclair RD, Kasprzak M, Miot HA. Minoxidil 1 mg oral versus minoxidil 5% topical solution for the treatment of female-pattern hair loss: a randomized clinical trial. J Am Acad Derm. 2020 Jan;82(1):252–53. doi:10.1016/j.jaad.2019.08.060.
  • Ring C, Heitmiller K, Correia E, Gabriel Z, Saedi N. Nutraceuticals for Androgenetic Alopecia. J Clin Aesthet Dermatol. 2022 Mar;15(3):26–29.
  • Ablon G, Kogan S. A Randomized, Double-Blind, Placebo-Controlled Study of a Nutraceutical Supplement for Promoting Hair Growth in Perimenopausal, Menopausal, and Postmenopausal Women with Thinning Hair. J Drugs Dermatol. 2021 Jan 1;20(1):55–61. doi:10.36849/JDD.5701.
  • Abdin R, Zhang Y, Jimenez JJ. Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways. Front Med (Lausanne). 2022 Mar 16;9:843127. doi:10.3389/fmed.2022.843127.
  • Gupta A, Bamimore M. Platelet-Rich Plasma Monotherapies for Androgenetic Alopecia: a Network Meta-Analysis and Meta-Regression Study. J Drugs Dermatol. 2022 Sep 1;21(9):943–52. doi:10.36849/JDD.6948.
  • RS E Jr, Ruiz S, DoAmaral P. Microneedling and Its Use in Hair Loss Disorders: a Systematic Review. Dermatol Ther (Heidelb). 2022 Jan;12(1):41–60. Epub 2021 Dec 1. doi:10.1007/s13555-021-00653-2.
  • Bharti J, Sonthalia S, Patil P, Dhurat R. Scalp threading with polydioxanone monofilament threads: a novel, effective and safe modality for hair restoration. J Eur Acad Dermatol Venereol. 2017 Nov;31(11):e492–e93. doi:10.1111/jdv.14336.
  • RS E Jr, Ruiz S. Use of Botulinum Toxin for Androgenic Alopecia: a Systematic Review. Skin Appendage Disord. 2022 Mar;8(2):93–100. doi:10.1159/000518574.
  • da Silveira SP, Moita SRU, da Silva SV, Rodrigues MFSD, da Silva DFT, Pavani C, MFSD R, da Silva SV, da Silva DDFT. The role of photobiomodulation when associated with microneedling in female pattern hair loss: a randomized, double blind, parallel group, three arm, clinical study protocol. Medicine (Baltimore). 2019 Mar;98(12):e14938. doi:10.1097/MD.0000000000014938.
  • Kim WS, Lee HI, Lee JW, Lim YY, Lee SJ, Kim BJ, Kim MN, Song KY, Park WS. Fractional photothermolysis laser treatment of male pattern hair loss. Dermatol Surg. 2011 Jan;37(1):41–51. DOI:10.1111/j.1524-4725.2010.01833.x. [ Epub 2010 Dec 28. PMID: 21199096].
  • Kim J, Kim HC, Kowsari K, Yoon K, Yoo SS. Transcutaneous application of ultrasound enhances the effects of finasteride in a murine model of androgenic alopecia. Ultrasonography. 2022 Apr;41(2):382–93. doi:10.14366/usg.21186. Epub 2021 Nov 10. PMID: 34963257; PMCID: PMC8942741.
  • https://www.drglat.com/hair-restoration/prp-for-hair-restoration/alma-ted/
  • Uebel CO, Piccinini PS, Spencer LSB, da Silveira JAM, da Silveira JAM. Female Pattern Hair Loss: why the Follicular Unit Transplantation Surgical Technique Remains a Good Option. Plast Reconstr Surg. 2021 Apr 1;147(4):839–49. doi:10.1097/PRS.0000000000007760.
  • Sinclair RD. Female pattern hair loss: a pilot study investigating combination therapy with low-dose oral minoxidil and spironolactone. Int J Dermatol. 2018 Jan;57(1):104–09. doi:10.1111/ijd.13838.
  • Olamiju B, Craiglow BG. Combination oral minoxidil and spironolactone for the treatment of androgenetic alopecia in adolescent girls. J Am Acad Dermatol. 2021 Jun;84(6):1689–91. doi:10.1016/j.jaad.2020.10.097.
  • Lotfi E, Aramianpour N, Salehi B. Combination of platelet-rich plasma and platelet gel in treatment of resistance androgenic alopecia: a case series study. J Cosmet Dermatol. 2022 Apr 5;21(10):4307–12. doi:10.1111/jocd.14963.
  • Ramadan WM, Hassan AM, Ismail MA, El Attar YA. Evaluation of adding platelet-rich plasma to combined medical therapy in androgenetic alopecia. J Cosmet Dermatol. 2021;20(5):1427–34. doi:10.1111/jocd.13935.
  • Avram MR, Cole JP, Gandelman M, Haber R, Knudsen R, Leavitt MT, RT L Jr, Puig CJ, Rose PT, Vogel JE, et al. Roundtable Consensus Meeting of the 9th Annual Meeting of the International Society of Hair Restoration Surgery. The potential role of minoxidil in the hair transplantation setting. Dermatol Surg. 2002 Oct;28(10):894–900. doi:10.1046/j.1524-4725.2002.02068.x.
  • https://www.hairdoc.com/contents/hair-loss-answers chap 9: drugs in hair loss
  • Sharma A, Surve R, Dhurat R, Sinclair R, Tan T, Zou Y, Müller Ramos P, Wambier C, Verner I, Kovacevic M, et al. Microneedling improves minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes. J Biol Regul Homeost Agents. 2020 Mar-Apr;34(2):659–61. doi:10.23812/19-385-L-51.
  • Seung Shin H, Hyun Won C, Ho Lee S, Kwon OS, Kim KH, Eun HC. Efficacy of 5% Minoxidil versus Combined 5% Minoxidil and 0.01% Tretinoin for Male Pattern Hair Loss. Am J Clin Dermatol. 2007;8(5):285–90. doi:10.2165/00128071-200708050-00003.
  • Liang X, Chang Y, Wu H, Liu Y, Zhao J, Wang L, Zhuo F. Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: a Prospective, Single-Center, Parallel-Group, Evaluator Blinded, Randomized Trial. Front Med (Lausanne). 2022 Jul 11;9:905140. doi:10.3389/fmed.2022.905140.
  • Mahe YF, Cheniti A, Tacheau C, Antonelli R, Planard-Luong L, de Bernard S, Buffat L, Barbarat P, Kanoun-Copy L. Low-Level Light Therapy Downregulates Scalp Inflammatory Biomarkers in Men with Androgenetic Alopecia and Boosts Minoxidil 2% to Bring a Sustainable Hair Regrowth Activity. Lasers Surg Med. 2021 Nov;53(9):1208–19 Epub 2021 May 11. doi:10.1002/lsm.23398.
  • Bao L, Zong H, Fang S, Zheng L, Li Y. Randomized trial of electrodynamic microneedling combined with 5% minoxidil topical solution for treating androgenetic alopecia in Chinese males and molecular mechanistic study of the involvement of the Wnt/β-catenin signaling pathway. J Dermatolog Treat. 2022 Feb;33(1):483–93. doi:10.1080/09546634.2020.1770162.
  • Tan PC, Zhang PQ, Xie Y, Gao YM, Li QF, Zhou SB, Liu Q, Liu K. Autologous Concentrated Growth Factors Combined with Topical Minoxidil for the Treatment of Male Androgenetic Alopecia: a Randomized Controlled Clinical Trial. Facial Plast Surg Aesthet Med. 2021 Jul-Aug;23(4):255–62. doi:10.1089/fpsam.2020.0288.
  • Hu R, Xu F, Sheng Y, Qi S, Han Y, Miao Y, Rui W, Yang Q. Combined treatment with oral finasteride and topical minoxidil in male androgenetic alopecia: a randomized and comparative study in Chinese patients. Dermatol Ther. 2015 Sep-Oct;28(5):303–08. doi:10.1111/dth.12246.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.