Effects of Bacillus subtilis C-3102 addition on nutrient digestibility, faecal characteristics, blood chemistry and faecal Lactobacilli spp., Enterococci spp., and Escherichia coli in healthy dogs

References

• Abd El-Wahab A, Chuppava B, Zeiger AL, Visscher C, Kamphues J. 2022. Nutrient digestibility and fecal quality in beagle dogs fed meat and bone meal added to dry food. Vet Sci. 9(4):164.
   PubMedGoogle Scholar
• Ahasan A, Agazzi A, Invernizzi G, Bontempo V, Savoini G. 2015. The beneficial role of probiotics in monogastric animal nutrition and health. J Dairy Vet & Anim Res. 2(4):1–20.
   Google Scholar
• AOAC 2019. Official methods of analysis, The Association of Official Analytical Chemists: 21st ed., Gaithersburg, MD, USA.
   Google Scholar
• Baillon M-LA, Marshall-Jones ZV, Butterwick RF. 2004. Effects of probiotic Lactobacillus acidophilus strain DSM13241 in healthy adult dogs. Am J Vet Res. 65(3):338–343.
   PubMed Web of Science ®Google Scholar
• Bastos TS, de Lima DC, Souza CMM, Maiorka A, de Oliveira SG, Bittencourt LC, Félix AP. 2020. Bacillus subtilis and Bacillus licheniformis reduce faecal protein catabolites concentration and odour in dogs. BMC Vet Res. 16(1):1–8.
   PubMed Web of Science ®Google Scholar
• Biagi G, Cipollini I, Pompei A, Zaghini G, Matteuzzi D. 2007. Effect of a Lactobacillus animalis strain on composition and metabolism of the intestinal microflora in adult dogs. Vet Microbiol. 124(1-2):160–165.
   PubMed Web of Science ®Google Scholar
• Biourge V, Vallet C, Levesque A, Sergheraert R, Chevalier S, Roberton J-L. 1998. The use of probiotics in the diet of dogs. J Nutr. 128(12):2730S–2732S.
   PubMed Web of Science ®Google Scholar
• Boroojeni FG, Vahjen W, Männer K, Blanch A, Sandvang D, Zentek J. 2018. Bacillus subtilis in broiler diets with different levels of energy and protein. Poult Sci. 97(11):3967–3976.
   PubMed Web of Science ®Google Scholar
• Chen Y, Min B, Cho J, Kwon O, Son K, Kim I, Kim S. 2006. Effects of dietary Enterococcus faecium SF68 on growth performance, nutrient digestibility, blood characteristics and faecal noxious gas content in finishing pigs. Asian Australas J Anim Sci. 19(3):406–411.
   Web of Science ®Google Scholar
• Chuppava B, Siebert DC, Visscher C, Kamphues J, Abd El-Wahab A. 2023. Impact of animal by-products on diet digestibility and fecal quality in beagle dogs. Life. 13(3):850.
   PubMedGoogle Scholar
• Collado MC, Isolauri E, Salminen S, Sanz Y. 2009. The impact of probiotic on gut health. Curr Drug Metab. 10(1):68–78.
   PubMed Web of Science ®Google Scholar
• Coppola M, Gil-Turnes C. 2004. Probióticos e resposta imune. Cienc Rural. 34(4):1297–1303.
   Google Scholar
• Craig J. 2021. Additives in pet food: are they safe? J Small Anim Pract. 62(8):624–635.
   PubMed Web of Science ®Google Scholar
• de Lima DC, Souza CMM, Nakamura N, Mesa D, de Oliveira SG, Félix AP. 2020. Dietary supplementation with Bacillus subtilis C-3102 improves gut health indicators and fecal microbiota of dogs. Anim Feed Sci Technol. 270:114672.
   Web of Science ®Google Scholar
• de-Oliveira LD, Takakura FS, Kienzle E, Brunetto MA, Teshima E, Pereira GT, Vasconcellos RS, Carciofi AC. 2012. Fibre analysis and fibre digestibility in pet foods-a comparison of total dietary fibre, neutral and acid detergent fibre and crude fibre. J Anim Physiol Anim Nutr (Berl). 96(5):895–906.
   PubMed Web of Science ®Google Scholar
• Deschamps C, Humbert D, Zentek J, Denis S, Priymenko N, Apper E, Blanquet-Diot S. 2022. From Chihuahua to Saint-Bernard: how did digestion and microbiota evolve with dog sizes. Int J Biol Sci. 18(13):5086–5102.
   PubMed Web of Science ®Google Scholar
• dos Santos Felssner K, Todesco H, Grande PA, Ogoshi RCS, dos Reis JS, FMdOB S, Vasconcellos RS. 2016. Dietetic combination of mannan-oligosaccharides and fructooligosaccharides modifies nitrogen metabolism in dogs. Semina: ciênc Agrár. 37(5):3335–3347.
   Web of Science ®Google Scholar
• Rychen G, Aquilina G, Azimonti G, Bampidis V, de Bastos ML, Bories G, Chesson A, Cocconcelli PS, Flachowsky G, et al. 2017. Safety and efficacy of calsporin® (Bacillus subtilis DSM15544) as a feed additive for dogs. EFSA J. 15:e04760.
   PubMed Web of Science ®Google Scholar
• FEDIAF 2019. Nutritional guidelines for complete and complementary pet food for cats and dogs. FEDIAF Bruxelles (Belgium).
   Google Scholar
• Feliciano M, Saad F, Logato P, Aquino A, José V, Roque N. 2009. Efeitos de probióticos sobre a digestibilidade, escore fecal e características hematológicas em cães. Arq Bras Med Vet Zootec. 61(6):1268–1274.
   Google Scholar
• Félix AP, Netto MVT, Murakami FY, Brito C, Oliveira S, Maiorka A. 2010. Digestibilidade e características das fezes de cães suplementados com Bacillus subtilis na dieta. Cienc Rural. 40(10):2169–2173.
   Google Scholar
• Fu CJ, Carter JN, Li Y, Porter JH, Kerley MS. 2006. Comparison of agar plate and real‐time PCR on enumeration of Lactobacillus, Clostridium perfringens and total anaerobic bacteria in dog faeces. Lett Appl Microbiol. 42(5):490–494.
   PubMed Web of Science ®Google Scholar
• Gagné JW, Wakshlag JJ, Simpson KW, Dowd SE, Latchman S, Brown DA, Brown K, Swanson KS, Fahey GC. 2013. Effects of a synbiotic on fecal quality, short-chain fatty acid concentrations, and the microbiome of healthy sled dogs. BMC Vet Res. 9(1):1–10.
   PubMedGoogle Scholar
• Garcia-Mazcorro JF, Lanerie DJ, Dowd SE, Paddock CG, Grützner N, Steiner JM, Ivanek R, Suchodolski JS. 2011. Effect of a multi-species synbiotic formulation on fecal bacterial microbiota of healthy cats and dogs as evaluated by pyrosequencing. FEMS Microbiol Ecol. 78(3):542–554.
   PubMed Web of Science ®Google Scholar
• Giang HH, Viet TQ, Ogle B, Lindberg JE. 2011. Effects of supplementation of probiotics on the performance, nutrient digestibility and faecal microflora in growing-finishing pigs. Asian Australas J Anim Sci. 24(5):655–661.
   Web of Science ®Google Scholar
• González-Ortiz G, Castillejos L, Mallo JJ, Àngels Calvo-Torras M, Dolores Baucells M. 2013. Effects of dietary supplementation of Bacillus amyloliquefaciens CECT 5940 and Enterococcus faecium CECT 4515 in adult healthy dogs. Arch Anim Nutr. 67(5):406–415.
   PubMed Web of Science ®Google Scholar
• Guan ZW, Yu EZ, Feng Q. 2021. Soluble dietary fiber, one of the most important nutrients for the gut microbiota. Molecules. 26(22):6802.
   PubMed Web of Science ®Google Scholar
• Hentges DJ. 1992. Gut flora and disease resistance. In: Fuller R, editor. Probiotics: the scientific basis. London, England: Springer, Chapman & Hall; p. 87–110.
   Google Scholar
• Herstad HK, Nesheim BB, L'Abée-Lund T, Larsen S, Skancke E. 2010. Effects of a probiotic intervention in acute canine gastroenteritis–a controlled clinical trial. J Small Anim Pract. 51(1):34–38.
   PubMed Web of Science ®Google Scholar
• Kara K. 2021. Comparison of dietary fibre, β-glucan, resistant and non-resistant starch and in vitro digestibility of commercial extruded dry food for adult dogs. J Anim Feed Sci. 30(4):379–390.
   Web of Science ®Google Scholar
• Kelley R, Levy K, Mundell P, Hayek MG. 2012. Effects of Varying Doses of a Probiotic Supplement Fed to Healthy Dogs Undergoing Kenneling Stress. Int J Appl Res Vet Med. 10(3):205–216.
   Web of Science ®Google Scholar
• Moir A. 2006. How do spores germinate? J Appl Microbiol. 101(3):526–530.
   PubMed Web of Science ®Google Scholar
• Montegiove N, Calzoni E, Cesaretti A, Pellegrino RM, Emiliani C, Pellegrino A, Leonardi L. 2022. The hard choice about dry pet food: comparison of protein and lipid nutritional qualities and digestibility of three different chicken-based formulations. Animals. 12(12):1538.
   Web of Science ®Google Scholar
• NRC 2006. Nutrient requirements of dogs and cats. National Academies Press.
   Google Scholar
• Paap P, Van der Laak J, Smit J, Nakamura N, Beynen A. 2016. Administration of Bacillus subtilis C-3102 (Calsporin®) may improve feces consistency in dogs with chronic diarrhea. Res Opin Anim Vet Sci. 6(8):256–260.
   Google Scholar
• Pilla R, Suchodolski JS. 2021. The gut microbiome of dogs and cats, and the influence of diet. Vet Clin North Am Small Anim Pract. 51(3):605–621.
   PubMed Web of Science ®Google Scholar
• Rossi G, Pengo G, Galosi L, Berardi S, Tambella AM, Attili AR, Gavazza A, Cerquetella M, Jergens AE, Guard BC, et al. 2020. Effects of the probiotic mixture Slab51®(SivoMixx®) as food supplement in healthy dogs: evaluation of fecal microbiota, clinical parameters and immune function. Front Vet Sci. 7:613.
   PubMed Web of Science ®Google Scholar
• Sauter SN, Benyacoub J, Allenspach K, Gaschen F, Ontsouka E, Reuteler G, Cavadini C, Knorr R, Blum JW. 2006. Effects of probiotic bacteria in dogs with food responsive diarrhoea treated with an elimination diet. J Anim Physiol Anim Nutr (Berl). 90(7-8):269–277.
   PubMed Web of Science ®Google Scholar
• Schauf S, Nakamura N, Castrillo C. 2019. Effect of Calsporin® (Bacillus subtilis C-3102) addition to the diet on faecal quality and nutrient digestibility in healthy adult dogs. J Appl Anim Nutr. 7
   Google Scholar
• Scheppach W. 1994. Effects of short chain fatty acids on gut morphology and function. Gut. 35(1 Suppl):S35–S38.
   PubMed Web of Science ®Google Scholar
• Sivamaruthi BS, Kesika P, Chaiyasut C. 2021. Influence of probiotic supplementation on health status of the dogs: a review. Appl Sci. 11(23):11384.
   Google Scholar
• Strickling JA, Harmon D, Dawson K, Gross K. 2000. Evaluation of oligosaccharide addition to dog diets: influences on nutrient digestion and microbial populations. Anim Feed Sci Technol. 86(3-4):205–219.
   Web of Science ®Google Scholar
• Strompfová V, Lauková A, Gancarčíková S. 2012. Effectivity of freeze-dried form of Lactobacillus fermentum AD1-CCM7421 in dogs. Folia Microbiol (Praha). 57(4):347–350.
   PubMed Web of Science ®Google Scholar
• Sun HY, Kim KP, Bae CH, Choi AJ, Paik HD, Kim IH. 2019. Evaluation of Weissella cibaria JW15 probiotic derived from fermented Korean vegetable product supplementation in diet on performance characteristics in adult beagle dog. Animals. 9(8):581.
   Web of Science ®Google Scholar
• Swanson KS, Grieshop CM, Flickinger EA, Bauer LL, Chow J, Wolf BW, Garleb KA, Fahey GC. 2002. Fructooligosaccharides and Lactobacillus acidophilus modify gut microbial populations, total tract nutrient digestibilities and fecal protein catabolite concentrations in healthy adult dogs. J Nutr. 132(12):3721–3731.
   PubMed Web of Science ®Google Scholar
• Wang J, Ji H. 2019. Influence of probiotics on dietary protein digestion and utilization in the gastrointestinal tract. Curr Protein Pept Sci. 20(2):125–131.
   PubMed Web of Science ®Google Scholar
• Weatherburn M. 1967. Phenol-hypochlorite reaction for determination of ammonia. Anal Chem. 39(8):971–974.
   Web of Science ®Google Scholar
• Weese JS, Arroyo L. 2003. Bacteriological evaluation of dog and cat diets that claim to contain probiotics. Can Vet J. 44(3):212–216.
   PubMed Web of Science ®Google Scholar
• Zeng MY, Inohara N, Nuñez G. 2017. Mechanisms of inflammation-driven bacterial dysbiosis in the gut. Mucosal Immunol. 10(1):18–26.
   PubMed Web of Science ®Google Scholar
• Zentek J, Fricke S, Hewicker-Trautwein M, Ehinger B, Amtsberg G, Baums C. 2004. Dietary protein source and manufacturing processes affect macronutrient digestibility, fecal consistency, and presence of fecal Clostridium perfringens in adult dogs. J Nutr. 134(8 Suppl):2158S–2161S.
   PubMed Web of Science ®Google Scholar
• Zhang HL, Li WS, Xu DN, Zheng WW, Liu Y, Chen J, Qiu ZB, Dorfman RG, Zhang J, Liu J. 2016. Mucosa-reparing and microbiota-balancing therapeutic effect of Bacillus subtilis alleviates dextrate sulfate sodium-induced ulcerative colitis in mice. Exp Ther Med. 12(4):2554–2562.
   PubMed Web of Science ®Google Scholar