An investigation of the assumed efficacy of methionine hydroxy analogue compared to DL-methionine by measuring growth performance, carcass traits, and GHR and IGF-I expression in broilers

References

• Agostini PS, Dalibard P, Mercier Y, van der Aar P, van der Klis JD. 2016. Comparison of methionine sources around requirement levels using a methionine efficacy method in 0 to 28 day old broilers. Poult Sci. 95(3):560–569. doi:10.3382/ps/pev340.
   PubMed Web of Science ®Google Scholar
• AOAC. 2005. Official methods of analysis. 18th ed. Washington (DC): AOAC.
   Google Scholar
• Aviagen. 2019. Broiler nutrition specifications. [accessed 2020 May]. http://en.aviagen.com/assets/Tech_ Center/Ross_Broiler/RossBroilerNutritionSpecs2019-EN.pdf.
   Google Scholar
• Aggrey SE, González-Cerón F, Rekaya R, Mercier Y. 2018. Gene expression differences in the methionine remethylation and transsulphuration pathways under methionine restriction and recovery with d,l-methionine or d,l-hmtba in meat-type chickens. J Anim Physiol Anim Nutr. 102(1):e468–e475. doi:10.1111/jpn.12779.
   PubMed Web of Science ®Google Scholar
• Batonon-Alavo DI, Manceaux C, Wittes JT, Rouffineau F, Mercier Y. 2023. New statistical approach shows that hydroxy-methionine is noninferior to DL-Methionine in 35-day-old broiler chickens. Poult Sci. 102(4):102519. doi:10.1016/j.psj.2023.102519.
   PubMed Web of Science ®Google Scholar
• Black JL, Hughes RJ, Nielsen SG, Tredrea AM, Flinn PC. 2009. Near infrared reflectance analysis of grains to estimate nutritional value for chickens. Proceedings of 20th Australian Poultry Science Symposium; 9–11th February; Sydney, New South Wales. p. 31–34.
   Google Scholar
• Brosnan JT, Brosnan ME, Bertolo RF, Brunton JA. 2007. Methionine: a metabolically unique amino acid. Livest. Sci. 112(1-2):2–7. doi:10.1016/j.livsci.2007.07.005.
   Web of Science ®Google Scholar
• Çenesiz AA, Çiftci I, Ceylan N. 2022. Effects of dl- and l-methionine supplementation on growth performance, carcass quality and relative bioavailability of methionine in broilers fed maize-soybean-based diets. J Anim Feed Sci. 31(2):142–151. doi:10.22358/jafs/147800/2022.
   Web of Science ®Google Scholar
• Conde-Aguilera JA, Cholet JCG, Lessire M, Mercier Y, Tesseraud S, van Milgen J. 2016. The level and source of free-methionine affect body composition and breast muscle traits in growing broilers1. Poult Sci. 95(10):2322–2331. doi:10.3382/ps/pew105.
   PubMed Web of Science ®Google Scholar
• Del Vesco AP, Gasparino E, Grieser DO, Zancanela V, Voltolini DM, Khatlab AS, Guimaraes SF, Soares MM, Neto ARO. 2015. Effects of methionine supplementation on the expression of protein deposition-related genes in acute heat stress-exposed broilers. PLOS One. 10(2):e0115821. doi:10.1371/journal.pone.0115821.
   PubMed Web of Science ®Google Scholar
• Del Vesco AP, Gasparino E, Oliveira Neto AR, Guimaraes SE, Marcato SM, Voltolini DM. 2013. Dietary methionine effects on igf-i and ghr mrna expression in broilers. Genet Mol Res. 12(4):6414–6423. doi:10.4238/2013.December.10.2.
   PubMed Web of Science ®Google Scholar
• Dibner JJ, Atwell CA, Ivey FJ. 1992. Effect of heat stress on 2-hydroxy-4-(methylthio)butanoic acid and dl-methionine absorption measured in vitro. Poult Sci. 71(11):1900–1910. doi:10.3382/ps.0711900.
   PubMed Web of Science ®Google Scholar
• Dibner JJ, Knight CD. 1984. Conversion of 2-hydroxy-4-(methylthio)butanoic acid to l-methionine in the chick − a stereospecific pathway. J Nutr. 114(9):1716–1723. doi:10.1093/jn/114.9.1716.
   PubMed Web of Science ®Google Scholar
• Drew MD, Van Kessel AG, Maenz DD. 2003. Absorption of methionine and 2-hydroxy-4-methylthiobutoanic acid in conventional and germ-free chickens. Poult Sci. 82(7):1149–1153. doi:10.1093/ps/82.7.1149.
   PubMed Web of Science ®Google Scholar
• EFSA. 2012. Scientific opinion on dl-methionine, dl-methionine sodium salt, the hydroxy analogue of methionine and the calcium salt of methionine hydroxy analogue in all animal species; on the isopropyl ester of methionine hydroxy analogue and dl-methionine technically pure protected with copolymer vinylpyridine/styrene in dairy cows; and on dl-methionine technically pure protected with ethylcellulose in ruminants. EFSA J. 10:2623.
   Google Scholar
• Esteve-Garcia E, Llaurado L. 1997. Performance, breast meat yield and abdominal fat deposition of male broiler chickens fed diets supplemented with DL-methionine or DLmethionine hydroxy analog free acid. Br Poult Sci. 38(4):397–404. doi:10.1080/00071669708418009.
   PubMed Web of Science ®Google Scholar
• Hoehler D, Lemme A, Jensen SK, Vieira SL. 2005. Relative effectiveness of methionine sources in diets for broiler chickens. J Appl Poult Res. 14(4):679–693. doi:10.1093/japr/14.4.679.
   Web of Science ®Google Scholar
• Johri TS, Mandal AB, Elangovan AV. 2004. Comparing bio-efficacy of liquid DL-methionine hydroxy analogue free acid with DL-methionine in broiler chickens. Asian Australas J Anim Sci. 17(1):102–108. doi:10.5713/ajas.2004.102.
   Web of Science ®Google Scholar
• Kim DH, An BK, Oh S, Keum MC, Lee S, Um JS, Ayasan T, Lee KW. 2019. Effects of different methionine sources on growth performance, meat yield and blood characteristics in broiler chickens. J Appl Anim Res. 47(1):230–235. doi:10.1080/09712119.2019.1617719.
   Web of Science ®Google Scholar
• Lemme A, Hoehler D, Brennan JJ, Mannion PF. 2002. Relative effectiveness of methionine hydroxy analog compared to dl-methionine in broiler chickens. Poult Sci. 81(6):838–845. doi:10.1093/ps/81.6.838.
   PubMed Web of Science ®Google Scholar
• Lemme A, Mitchell M. 2008. Examination of the composition of the luminal fluid in the small intestine of broilers and absorption of amino acids under various ambient temperatures measured in vivo. Int J Poult Sci. 7(3):223–233. doi:10.3923/ijps.2008.223.233.
   Google Scholar
• Lemme A, Naranjo V, Dorigam JCD. 2020. Utilization of methionine sources for growth and met plus cys deposition in broilers. Animals. 10(12):2240. doi:10.3390/ani10122240.
   Web of Science ®Google Scholar
• Li Z, Dorigam JCD, Afsar A, Lemme A, Viana GS, Musharbash E. 2023. Evaluation of methionine sources on performance and carcass traits of broilers at different dietary sulfur amino acid levels under northern European and middle Eastern conditions. Proceedings of the Poultry Science Association 112th Annual Meeting; July 10-13; Philadelphia, Pennysylvania. p. 91.
   Google Scholar
• Liu YL, Song GL, Yi GF, Hou YQ, Huang JW, Vazquez-Anon M, Knight CD. 2006. Effect of supplementing 2-hydroxy-4-(methylthio) butanoic acid and dl-methionine in corn-soybean-cottonseed meal diets on growth performance and carcass quality of broilers. Asian Australas J Anim Sci. 19(8):1197–1205. doi:10.5713/ajas.2006.1197.
   Web of Science ®Google Scholar
• Liu YL, Yi GF, Song GL, Hou YQ, Huang JW, Vazquez-Anon M, Knight CD. 2007. Impact of feeding 2-hydroxy-4-(methylthio)butanoic acid and dl-methionine supplemented maize-soybean-rapeseed meal diets on growth performance and carcase quality of broilers. Br Poult Sci. 48(2):190–197. doi:10.1080/00071660701247814.
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and 2−ΔΔCT method. Methods. 25(4):402–408. doi:10.1006/meth.2001.1262.
   PubMed Web of Science ®Google Scholar
• Llames CR, Fontaine J. 1994. Determination of amino acids in feeds: collaborative study. J AOAC Int. 77(6):1362–1402. doi:10.1093/jaoac/77.6.1362.
   Web of Science ®Google Scholar
• Maenz DD, Engele-Schaan CM. 1996. Methionine and 2-hydroxy-4-methylthiobutanoic acid are transported by distinct Na+-dependent and H+-dependent systems in the brush border membrane of the chick intestinal epithelium. J Nutr. 126(2):529–536. doi:10.1093/jn/126.2.529.
   PubMed Web of Science ®Google Scholar
• Payne RL, Lemme A, Seko H, Hashimoto Y, Fujisaki H, Koreleski J, Swiatkiewicz S, Szczurek W, Rostagno H. 2006. Bioavailability of methionine hydroxy analog-free acid relative to dl-methionine in broilers. Anim Sci J. 77(4):427–439. doi:10.1111/j.1740-0929.2006.00369.x.
   Web of Science ®Google Scholar
• Pontin CA, Vieira SL, Stefanello C, Kipper M, Kindlein L, Simões CT, Gonzalez-Esquerra R. 2018. Estimation of broiler responses to increased dietary methionine hydroxy analogue [dl-2-hydroxy-(4-methylthio) butanoic acid] using linear and nonlinear regression models. Poult Sci. 97(3):865–873. doi:10.3382/ps/pex330.
   PubMed Web of Science ®Google Scholar
• Richards JD, Atwell CA, Vazquez-Anon M, Dibner JJ. 2005. Comparative in vitro and in vivo absorption of 2-hydroxy-4(methylthio) butanoic acid and methionine in the broiler chicken. Poult Sci. 84(9):1397–1405. doi:10.1093/ps/84.9.1397.
   PubMed Web of Science ®Google Scholar
• Sangali CP, Bruno LDG, Nunes RV, Neto ARD, Pozza PC, de Oliveira TMM, Frank R, Schone RA. 2014. Bioavailability of different methionine sources for growing broilers. R Bras Zootec. 43(3):140–145. doi:10.1590/S1516-35982014000300006.
   Web of Science ®Google Scholar
• Uddin ME, van Lingen HJ, da Silva-Pires PG, Batonon-Alavo DI, Rouffineau F, Kebreab E. 2022. Evaluating growth response of broiler chickens fed diets supplemented with synthetic DL-methionine or DL-hydroxy methionine: a meta-analysis. Poult Sci. 101(5):101762. doi:10.1016/j.psj.2022.101762.
   PubMed Web of Science ®Google Scholar
• Ullrich C, Langeheine M, Brehm R, Taube V, Rosillo Galera M, Rohn K, Popp J, Visscher C. 2019. Influence of different methionine sources on performance and slaughter characteristics of broilers. Animals. 9(11):984. doi:10.3390/ani9110984.
   Web of Science ®Google Scholar
• Valdes EV, Leeson S. 1992. Near infrared reflectance analysis as a method to measure metabolizable energy in complete poultry feeds. Poult Sci. 71(7):1179–1187. doi:10.3382/ps.0711179.
   Web of Science ®Google Scholar
• VDLUFA. 1997. Bestimmung von DL-2-hydroxy-4-methy-mercaptobuttersäure nach hydrolyse (Gesamt MHAR) [Determination of DL-2-hydroxy-4-methyl-mercaptobutyric acid after hydrolysis (total MHAR)], Methode 4.11.4 Methodenbuch Band III, Die chemische Untersuchung von Futtermitteln, 4th Supplement. Darmstadt, Germany: VDLUFA Verlag.
   Google Scholar
• Wallis IR. 1999. Dietary supplements of methionine increase breast meat yield and decrease abdominal fat in growing broiler chickens. Aust J Exp Agric. 39(2):131–141. doi:10.1071/EA98130.
   Google Scholar
• Wen C, Wu P, Chen YP, Wang T, Zhou YM. 2014. Methionine improves the performance and breast muscle growth of broilers with lower hatching weight by altering the expression of genes associated with the insulin-like growth factor-i signalling pathway. Br J Nutr. 111(2):201–206. doi:10.1017/S0007114513002419.
   PubMed Web of Science ®Google Scholar
• Young RJ, Norris LC, Heuser GF. 1955. The chick’s requirement for folic acid in the utilization of choline and its precursors betaine and methylaminoethanol. J Nutr. 55(3):353–362. doi:10.1093/jn/55.3.353.
   PubMed Web of Science ®Google Scholar
• Zeitz JO, Mohrmann S, Fehse L, Most E, Helmbrecht A, Saremi B, Eder K. 2018. Tissue and plasma antioxidant status in response to dietary methionine concentration and source in broilers. J Anim Physiol Anim Nutr. 102(4):999–1011. doi:10.1111/jpn.12909.
   PubMed Web of Science ®Google Scholar
• Zeitz JO, Mohrmann S, Käding SC, Devlikamov M, Niewalda I, Whelan R, Helmbrecht A, Eder K. 2019. Effects of methionine on muscle protein synthesis and degradation pathways in broilers. J Anim Physiol Anim Nutr. 103(1):191–203. doi:10.1111/jpn.13026.
   PubMed Web of Science ®Google Scholar
• Zhang S, Gilbert ER, Noonan KJT, Saremi B, Wong EA. 2018. Gene expression and activity of methionine converting enzymes in broiler chickens fed methionine isomers or precursors. Poult Sci. 97(6):2053–2063. doi:10.3382/ps/pey037.
   PubMed Web of Science ®Google Scholar