2,706
Views
0
CrossRef citations to date
0
Altmetric
Review Article

Suicidality risk after using cannabis and cannabinoids: An umbrella review

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon
Pages 50-63 | Received 19 Jan 2023, Accepted 25 Jun 2023, Published online: 10 Jul 2023

References

  • Armoon B, SoleimanvandiAzar N, Fleury M-J, Noroozi A, Bayat A-H, Mohammadi R, Ahounbar E, Fattah Moghaddam L. 2021. Prevalence, sociodemographic variables, mental health condition, and type of drug use associated with suicide behaviors among people with substance use disorders: a systematic review and meta-analysis. J Addict Dis. 39(4):550–569. doi: 10.1080/10550887.2021.1912572.
  • Bagge CL, Borges G. 2017. Acute substance use as a warning sign for suicide attempts: a case-crossover examination of the 48 hours prior to a recent suicide attempt. J Clin Psychiatry. 78(06):691–696. doi: 10.4088/JCP.15m10541.
  • Bahji A, Danilewitz M, Vazquez G, Patten S. 2021. The prevalence of cannabis use disorder comorbidity in individuals with bipolar disorder: a systematic review and meta-analysis. Canadian J Addict. 12(3):22–38. doi: 10.1097/CXA.0000000000000123.
  • Bartoli F, Crocamo C, Carrà G. 2019. Cannabis use disorder and suicide attempts in bipolar disorder: a meta-analysis. Neurosci Biobehav Rev. 103:14–20. doi: 10.1016/j.neubiorev.2019.05.017.
  • Borges G, Bagge CL, Orozco R. 2016. A literature review and meta-analyses of cannabis use and suicidality. J Affect Disord. 195:63–74. doi: 10.1016/j.jad.2016.02.007.
  • Breet E, Goldstone D, Bantjes J. 2018. Substance use and suicidal ideation and behaviour in low- and middle-income countries: a systematic review. BMC Public Health. 18(1). doi: 10.1186/s12889-018-5425-6. https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-018-5425-6#citeas
  • Calabria B, Degenhardt L, Hall W, Lynskey M. 2010. Does cannabis use increase the risk of death? Systematic review of epidemiological evidence on adverse effects of cannabis use. Drug Alcohol Rev. 29(3):318–330. doi: 10.1111/j.1465-3362.2009.00149.x.
  • Campeny E, López-Pelayo H, Nutt D, Blithikioti C, Oliveras C, Nuño L, Maldonado R, Florez G, Arias F, Fernández-Artamendi S, et al. 2020. The blind men and the elephant: systematic review of systematic reviews of cannabis use related health harms. Eur Neuropsychopharmacol. 33:1–35. doi: 10.1016/j.euroneuro.2020.02.003.
  • Carrà G, Bartoli F, Crocamo C, Brady KT, Clerici M. 2014. Attempted suicide in people with co-occurring bipolar and substance use disorders: systematic review and meta-analysis. J Affect Disord. 167:125–135. doi: 10.1016/j.jad.2014.05.066.
  • Carvalho JV, Souza LS, Moreira EC. 2022. Association between cannabis use and suicidal behavior: a systematic review of cohort studies. Psychiatry Res. 312:114555. doi: 10.1016/j.psychres.2022.114555.
  • Chapman C, Slade T, Swift W, Keyes K, Tonks Z, Teesson M. 2017. Evidence for sex convergence in prevalence of cannabis use: a systematic review and meta-regression. J Stud Alcohol Drugs. 78(3):344–352. doi: 10.15288/jsad.2017.78.344.
  • Chiappini S, Mosca A, Miuli A, Santovito MC, Orsolini L, Corkery JM, Guirguis A, Pettorruso M, Martinotti G, Di Giannantonio M, et al. 2021. New psychoactive substances and suicidality: a systematic review of the current literature. Medicina. 57(6):580. doi: 10.3390/medicina57060580.
  • Collin C, Ehler E, Waberzinek G, Alsindi Z, Davies P, Powell K, Notcutt W, O'Leary C, Ratcliffe S, Nováková I, et al. 2010. A double-blind, randomized, placebo-controlled, parallel-group study of Sativex, in subjects with symptoms of spasticity due to multiple sclerosis. Neurol Res. 32(5):451–459. doi: 10.1179/016164109X12590518685660.
  • Conner KR, Goldston DB. 2007. Rates of suicide among males increase steadily from age 11 to 21: developmental framework and outline for prevention. Aggres Violent Behav. 12(2):193–207. doi: 10.1016/j.avb.2006.07.002.
  • Crean RD, Crane NA, Mason BJ. 2011. An evidence based review of acute and long-term effects of cannabis use on executive cognitive functions. J Addict Med. 5(1):1–8. doi: 10.1097/ADM.0b013e31820c23fa.
  • Darke S, Duflou J, Torok M. 2009. Toxicology and circumstances of completed suicide by means other than overdose. J Forensic Sci. 54(2):490–494. doi: 10.1111/j.1556-4029.2008.00967.x.
  • De Wit H. 2009. Impulsivity as a determinant and consequence of drug use: a review of underlying processes. Addict Biol. 14(1):22–31. doi: 10.1111/j.1369-1600.2008.00129.x.
  • Degenhardt L, Hall W, Lynskey M. 2003. Exploring the association between cannabis use and depression. Addiction. 98(11):1493–1504. doi: 10.1046/j.1360-0443.2003.00437.x.
  • Doucette ML, Borrup KT, Lapidus G, Whitehill JM, McCourt AD, Crifasi CK. 2021. Effect of Washington State and Colorado’s cannabis legalization on death by suicides. Prev Med. 148:106548. doi: 10.1016/j.ypmed.2021.106548.
  • Escelsior A, Belvederi Murri M, Corsini GP, Serafini G, Aguglia A, Zampogna D, Cattedra S, Nebbia J, Trabucco A, Prestia D, et al. 2021. Cannabinoid use and self-injurious behaviours: a systematic review and meta-analysis. J Affect Disord. 278:85–98. doi: 10.1016/j.jad.2020.09.020.
  • Fergusson DM, Boden JM, Horwood LJ. 2006. Cannabis use and other illicit drug use: testing the cannabis gateway hypothesis. Addiction. 101(4):556–569. doi: 10.1111/j.1360-0443.2005.01322.x.
  • Fergusson DM, Horwood LJ, Swain‐Campbell N. 2002. Cannabis use and psychosocial adjustment in adolescence and young adulthood. Addiction. 97(9):1123–1135. doi: 10.1046/j.1360-0443.2002.00103.x.
  • Fresán A, Dionisio-García DM, González-Castro TB, Ramos-Méndez M, Castillo-Avila RG, Tovilla-Zárate CA, Juárez-Rojop IE, López-Narváez ML, Genis-Mendoza AD, Nicolini H. 2022. Cannabis smoking increases the risk of suicide ideation and suicide attempt in young individuals of 11–21 years: a systematic review and meta-analysis. J Psychiatr Res. 153:90–98. doi: 10.1016/j.jpsychires.2022.06.053.
  • Gobbi G, Atkin T, Zytynski T, Wang S, Askari S, Boruff J, Ware M, Marmorstein N, Cipriani A, Dendukuri N, et al. 2019. Association of cannabis use in adolescence and risk of depression, anxiety, and suicidality in young adulthood: a systematic review and meta-analysis. JAMA Psychiatry. 76(4):426. doi: 10.1001/jamapsychiatry.2018.4500.
  • Hodgson K, Almasy L, Knowles EEM, Kent JW, Curran JE, Dyer TD, Göring HHH, Olvera RL, Woolsey MD, Duggirala R, et al. 2017. The genetic basis of the comorbidity between cannabis use and major depression. Addiction. 112(1):113–123. doi: 10.1111/add.13558.
  • Ilgen MA, Burnette ML, Conner KR, Czyz E, Murray R, Chermack S. 2010. The association between violence and lifetime suicidal thoughts and behaviors in individuals treated for substance use disorders. Addict Behav. 35(2):111–115. doi: 10.1016/j.addbeh.2009.09.010.
  • Karanikola M, Zisimou P, Nystazaki M, Koutrouba A, Severinsson E. 2019. Association between illegal use of substances and suicidal behavior in school students: an integrative review of empirical data. J Child Adolesc Psychiatr Nurs. 32(2):80–101. doi: 10.1111/jcap.12228.
  • Klein P, Devinsky O, French J, Harden C, Krauss GL, McCarter R, Sperling MR. 2021. Suicidality risk of newer antiseizure medications: a meta-analysis. JAMA Neurol. 78(9):1118–1127. doi: 10.1001/jamaneurol.2021.2480.
  • Kung H-C, Pearson JL, Liu X. 2003. Risk factors for male and female suicide decedents ages 15–64 in the United States. Soc Psychiatry Psychiatr Epidemiol. 38(8):419–426. doi: 10.1007/s00127-003-0656-x.
  • Lynskey M, Hall W. 2000. The effects of adolescent cannabis use on educational attainment: a review. Addiction. 95(11):1621–1630. doi: 10.1046/j.1360-0443.2000.951116213.x.
  • Lynskey MT, Glowinski AL, Todorov AA, Bucholz KK, Madden PA, Nelson EC, Statham DJ, Martin NG, Heath AC. 2004. Major depressive disorder, suicidal ideation, and suicide attempt in twins discordant for cannabis dependence and early-onset cannabis use. Arch Gen Psychiatry. 61(10):1026–1032. doi: 10.1001/archpsyc.61.10.1026.
  • Macleod J, Oakes R, Copello A, Crome L, Egger M, Hickman M, Oppenkowski T, Stokes-Lampard H, Smith GD. 2004. Psychological and social sequelae of cannabis and other illicit drug use by young people: a systematic review of longitudinal, general population studies. Lancet. 363(9421):1579–1588. doi: 10.1016/S0140-6736(04)16200-4.
  • Mark Anderson D, Hansen B, Rees DI. 2015. Medical marijuana laws and teen marijuana use. Am Law Econ Rev. 17(2):495–528. doi: 10.1093/aler/ahv002.
  • Moore TH, Zammit S, Lingford-Hughes A, Barnes TR, Jones PB, Burke M, Lewis G. 2007. Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review [Article]. Lancet. 370(9584):319–328. doi: 10.1016/S0140-6736(07)61162-3.
  • Otten R, Engels RC. 2013. Testing bidirectional effects between cannabis use and depressive symptoms: moderation by the serotonin transporter gene. Addict Biol. 18(5):826–835. doi: 10.1111/j.1369-1600.2011.00380.x.
  • Pieper D, Antoine SL, Mathes T, Neugebauer EA, Eikermann M. 2014. Systematic review finds overlapping reviews were not mentioned in every other overview. J Clin Epidemiol. 67(4):368–375. doi: 10.1016/j.jclinepi.2013.11.007.
  • Pinto JV, Medeiros LS, Santana da Rosa G, Santana de Oliveira CE, Crippa JAS, Passos IC, Kauer-Sant’Anna M. 2019. The prevalence and clinical correlates of cannabis use and cannabis use disorder among patients with bipolar disorder: a systematic review with meta-analysis and meta-regression. Neurosci Biobehav Rev. 101:78–84. doi: 10.1016/j.neubiorev.2019.04.004.
  • Rioux C, Huet A-S, Castellanos-Ryan N, Fortier L, Le Blanc M, Hamaoui S, Geoffroy M-C, Renaud J, Seguin JR. 2021. Substance use disorders and suicidality in youth: a systematic review and meta-analysis with a focus on the direction of the association. PLOS One. 16(8):e0255799. doi: 10.1371/journal.pone.0255799.
  • Rudd MD, Berman AL, Joiner TE, Jr Nock MK, Silverman MM, Mandrusiak M, Van Orden K, Witte T. 2006. Warning signs for suicide: theory, research, and clinical applications. Suicide Life Threat Behav. 36(3):255–262. doi: 10.1521/suli.2006.36.3.255.
  • Schaffer A, Isometsä ET, Tondo L, D HM, Turecki G, Reis C, Cassidy F, Sinyor M, Azorin JM, Kessing LV, et al. 2015. International Society for Bipolar Disorders Task Force on Suicide: meta-analyses and meta-regression of correlates of suicide attempts and suicide deaths in bipolar disorder. Bipolar Disord. 17(1):1–16. doi: 10.1111/bdi.12271.
  • Schmidt K, Tseng I, Phan A, Fong T, Tsuang J. 2020. A systematic review: adolescent cannabis use and suicide. Addict Disord Treat. 19(3):146–151. doi: 10.1097/ADT.0000000000000196.
  • Serafini G, Pompili M, Innamorati M, Rihmer Z, Sher L, Girardi P. 2012. Can cannabis increase the suicide risk in psychosis? A critical review. Curr Pharm Des. 18(32):5165–5187. doi: 10.2174/138161212802884663.
  • Shea BJ, Reeves BC, Wells G, Thuku M, Hamel C, Moran J, et al. 2017. AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both BMJ 2017; 358 :j4008 doi: 10.1136/bmj.j4008.
  • Sher L, Oquendo MA. 2023. Suicide: An Overview for Clinicians. Medical Clinics of North America. 107(1):119–130. https://www.sciencedirect.com/science/article/abs/pii/S0025712522000402?via%3Dihub
  • Shi Y, Lenzi M, An R. 2015. Cannabis liberalization and adolescent cannabis use: a cross-national study in 38 countries. PLOS One. 10(11):e0143562. doi: 10.1371/journal.pone.0143562.
  • Sideli L, Quigley H, La Cascia C, Murray RM. 2020. Cannabis use and the risk for psychosis and affective disorders. J Dual Diagn. 16(1):22–42. doi: 10.1080/15504263.2019.1674991.
  • Smith PA, Slaven M, Shaw E, Chow E, Wolt A. 2017. Medical cannabis use in military and police veterans diagnosed with post-traumatic stress disorder (PTSD). J Pain Manag. 10(4):397–405.
  • Solowij N, Michie PT. 2007. Cannabis and cognitive dysfunction: parallels with endophenotypes of schizophrenia? J Psychiat Neurosci. 32(1):30–52.
  • Stringer S, Minică CC, Verweij KJ, Mbarek H, Bernard M, Derringer J, van Eijk KR, Isen JD, Loukola A, Maciejewski DF et al. 2016. Genome-wide association study of lifetime cannabis use based on a large metaanalytic sample of 32 330 subjects from the International Cannabis Consortium. Transl Psychiatry. 6(3):e769. eng. https://pubmed.ncbi.nlm.nih.gov/27023175/
  • Substance Abuse and Mental Health Services Administration. 2010. Results from the 2009 National Survey on Drug Use and Health: Volume I. Summary of National Findings (Office of Applied Studies, NSDUH Series H-38A, HHS Publication No. SMA 10-4586Findings). Rockville, MD.
  • Tait RJ, Caldicott D, Mountain D, Hill SL, Lenton S. 2016. A systematic review of adverse events arising from the use of synthetic cannabinoids and their associated treatment. Clin Toxicol. 54(1):1–13. doi: 10.3109/15563650.2015.1110590.
  • Thabet P, Joshi A, MacDonald E, Hutton B, Cheng W, Stevens A, Kanji S. 2021. Clinical and pharmacokinetic/dynamic outcomes of prolonged infusions of beta-lactam antimicrobials: an overview of systematic reviews. PLOS One. 16(1):e0244966. doi: 10.1371/journal.pone.0244966.
  • Tourjman SV, Buck G, Jutras-Aswad D, Khullar A, McInerney S, Saraf G, Pinto JV, Potvin S, Poulin MJ, Frey BN, et al. 2023. Canadian Network for Mood and Anxiety Treatments (CANMAT) task force report: a systematic review and recommendations of cannabis use in bipolar disorder and major depressive disorder. Can J Psychiatry. 68(5):299–311. doi: 10.1177/07067437221099769.
  • Turna J, MacKillop J. 2021. Cannabis use among military veterans: a great deal to gain or lose?. Clin Psychol Rev. 84:101958. doi: 10.1016/j.cpr.2021.101958.
  • Weeks M, Colman I. 2017. Predictors of suicidal behaviors in Canadian adolescents with no recent history of depression. Arch Suicide Res. 21(2):354–364. doi: 10.1080/13811118.2016.1193076.
  • Welty L, Harrison A, Abram K, Olson N, Aaby D, McCoy K. 2019. Substance Abuse and Mental Health Services Administration. Key substance use and mental health indicators in the United States: results from the 2016 national survey on drug use and health (HHS Publication No. SMA 17-5044, NSDUH Series H-52). Rockville, MD: Center for Behavioral Health Statistics and Quality. (Substance Abuse and Mental Health Services Administration Retrieved College of Health Sciences. 106(5):128).
  • Whitlow CT, Liguori A, Livengood LB, Hart SL, Mussat-Whitlow BJ, Lamborn CM, Laurienti PJ, Porrino LJ. 2004. Long-term heavy marijuana users make costly decisions on a gambling task. Drug Alcohol Depend. 76(1):107–111. doi: 10.1016/j.drugalcdep.2004.04.009.