Molecular mechanism of infectious spleen and kidney necrosis virus in manipulating the hypoxia-inducible factor pathway to augment virus replication

References

• Kaelin WJ, Ratcliffe PJ. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol Cell. 2008;30(4):393–15. doi: 10.1016/j.molcel.2008.04.009
   PubMed Web of Science ®Google Scholar
• Duan C. Hypoxia-inducible factor 3 biology: complexities and emerging themes. Am J Physiol-Cell Ph. 2016;310(4):C260–9. doi: 10.1152/ajpcell.00315.2015
   PubMed Web of Science ®Google Scholar
• Majmundar AJ, Wong WJ, Simon MC. Hypoxia-inducible factors and the response to hypoxic stress. Mol Cell. 2010;40(2):294–309. doi: 10.1016/j.molcel.2010.09.022
   PubMed Web of Science ®Google Scholar
• Palazon A, Goldrath AW, Nizet V, et al. HIF transcription factors, inflammation, and immunity. Immunity. 2014;41(4):518–528. doi: 10.1016/j.immuni.2014.09.008
   PubMed Web of Science ®Google Scholar
• Xiao W. The hypoxia signaling pathway and hypoxic adaptation in fishes. Sci China Life Sci. 2015;58(2):148–155. doi: 10.1007/s11427-015-4801-z
   PubMed Web of Science ®Google Scholar
• Jaakkola P, Mole DR, Maxwell PH, et al. Targeting of HIF-α to the von hippel-lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science. 2001;292(5516):468–472. doi: 10.1126/science.1059796
   PubMed Web of Science ®Google Scholar
• Sim J, Cowburn AS, Palazon A, et al. The factor inhibiting HIF asparaginyl hydroxylase regulates oxidative metabolism and accelerates metabolic adaptation to hypoxia. Cell Metab. 2018;27(4):898–913.e7. doi: 10.1016/j.cmet.2018.02.020
   PubMed Web of Science ®Google Scholar
• Schofield CJ, Ratcliffe PJ. Oxygen sensing by HIF hydroxylases. Nat Rev Mol Cell Bio. 2004;5(5):343–354. doi: 10.1038/nrm1366
   PubMed Web of Science ®Google Scholar
• Huang R, Huestis M, Gan ES, et al. Hypoxia and viral infectious diseases. JCI Insight. 2021;6(7). doi: 10.1172/jci.insight.147190
   Web of Science ®Google Scholar
• McFarlane S, Nicholl MJ, Sutherland JS, et al. Interaction of the human cytomegalovirus particle with the host cell induces hypoxia-inducible factor 1 alpha. Virology. 2011;414(1):83–90. doi: 10.1016/j.virol.2011.03.005
   PubMed Web of Science ®Google Scholar
• Kilani MM, Mohammed KA, Nasreen N, et al. RSV causes HIF-1α stabilization via NO release in primary bronchial epithelial cells. Inflammation. 2004;28(5):245–251. doi: 10.1007/s10753-004-6047-y
   PubMed Web of Science ®Google Scholar
• Mazzon M, Peters NE, Loenarz C, et al. A mechanism for induction of a hypoxic response by vaccinia virus. Proc Natl Acad Sci, USA. 2013;110(30):12444–12449. doi: 10.1073/pnas.1302140110
   PubMed Web of Science ®Google Scholar
• Guo Y, Meng X, Ma J, et al. Human papillomavirus 16 E6 contributes HIF-1α induced warburg effect by attenuating the VHL-HIF-1α interaction. Int J Mol Sci. 2014;15(5):7974–7986. doi: 10.3390/ijms15057974
   PubMed Web of Science ®Google Scholar
• Hwang II, Watson IR, Der SD, et al. Loss of VHL confers hypoxia-inducible factor (HIF)-dependent resistance to vesicular stomatitis virus: role of HIF in antiviral response. J Virol. 2006;80(21):10712–10723. doi: 10.1128/JVI.01014-06
   PubMed Web of Science ®Google Scholar
• Cho IR, Kaowinn S, Moon J, et al. Oncotropic H-1 parvovirus infection degrades HIF-1α protein in human pancreatic cancer cells independently of VHL and RACK1. Int J Oncol. 2015;46(5):2076–2082. doi: 10.3892/ijo.2015.2922
   PubMed Web of Science ®Google Scholar
• Bondad-Reantaso MG, Subasinghe RP, Arthur JR, et al. Disease and health management in Asian aquaculture. Vet Parasitol. 2005;132(3–4):249–272. doi: 10.1016/j.vetpar.2005.07.005
   PubMed Web of Science ®Google Scholar
• Wang YQ, Lu L, Weng SP, et al. Molecular epidemiology and phylogenetic analysis of a marine fish infectious spleen and kidney necrosis virus-like (ISKNV-like) virus. Arch Virol. 2007;152(4):763–773. doi: 10.1007/s00705-006-0870-4
   PubMed Web of Science ®Google Scholar
• He J, Yu Y, Li ZM, et al. Hypoxia triggers the outbreak of infectious spleen and kidney necrosis virus disease through viral hypoxia response elements. Virulence. 2022;13(1):714–726. doi: 10.1080/21505594.2022.2065950
   PubMed Web of Science ®Google Scholar
• Dong C, Weng S, Shi X, et al. Development of a mandarin fish siniperca chuatsi fry cell line suitable for the study of infectious spleen and kidney necrosis virus (ISKNV. Virus Res. 2008;135(2):273–281. doi: 10.1016/j.virusres.2008.04.004
   PubMed Web of Science ®Google Scholar
• Lin YF, He J, Zeng RY, et al. Deletion of the infectious spleen and kidney necrosis virus ORF069L reduces virulence to mandarin fish siniperca chuatsi. Fish Shellfish Immunol. 2019;95:328–335. doi: 10.1016/j.fsi.2019.10.039
   PubMed Web of Science ®Google Scholar
• Cockman ME, Webb JD, Kramer HB, et al. Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins. Mol & Cell Proteomics. 2009;8(3):535–546. doi: 10.1074/mcp.M800340-MCP200
   PubMed Web of Science ®Google Scholar
• Milkiewicz M, Pugh CW, Egginton S. Inhibition of endogenous HIF inactivation induces angiogenesis in ischaemic skeletal muscles of mice. J Physiol-London. 2004;560(1):21–26. doi: 10.1113/jphysiol.2004.069757
   PubMed Web of Science ®Google Scholar
• Ellinghaus P, Heisler I, Unterschemmann K, et al. BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I. Cancer Med. 2013;2(5):611–624. doi: 10.1002/cam4.112
   PubMed Web of Science ®Google Scholar
• Yuan JM, Chen YS, He J, et al. Identification and differential expression analysis of MicroRNAs encoded by tiger frog virus in cross-species infection in vitro. Virol J. 2016;13(1):73. doi: 10.1186/s12985-016-0530-6
   PubMedGoogle Scholar
• Zeng R, Pan W, Lin Y, et al. Development of a gene-deleted live attenuated candidate vaccine against fish virus (ISKNV) with low pathogenicity and high protection. Iscience. 2021;24:102750. doi: 10.1016/j.isci.2021.102750
   PubMed Web of Science ®Google Scholar
• Chen DY, Fabrizio JA, Wilkins SE, et al. Ankyrin repeat proteins of orf virus influence the cellular hypoxia response pathway. J Virol. 2017;91(1). doi: 10.1128/JVI.01430-16
   Web of Science ®Google Scholar
• Feng J, Zhang Y, She X, et al. Hypermethylated gene ANKDD1A is a candidate tumor suppressor that interacts with FIH1 and decreases HIF1α stability to inhibit cell autophagy in the glioblastoma multiforme hypoxia microenvironment. Oncogene. 2019;38(1):103–119. doi: 10.1038/s41388-018-0423-9
   PubMed Web of Science ®Google Scholar
• Mercer AA, Fleming SB, Ueda N. F-box-like domains are present in most poxvirus ankyrin repeat proteins. Vir Gen. 2005;31(2):127–133. doi: 10.1007/s11262-005-1784-z
   PubMed Web of Science ®Google Scholar
• Willems ARMS, Schwab M, Tyers M. A hitchhiker’s guide to the cullin ubiquitin ligases: SCF and its kin. Biochim Biophys Acta. 2004;1695(1–3):133–170. doi: 10.1016/j.bbamcr.2004.09.027
   PubMed Web of Science ®Google Scholar
• Pelster B, Egg M. Hypoxia-inducible transcription factors in fish: expression, function and interconnection with the circadian clock. J Exp Biol. 2018;221(13). doi: 10.1242/jeb.163709
   PubMed Web of Science ®Google Scholar
• Semenza GL. Oxygen sensing, homeostasis, and disease. New Engl J Med. 2011;365(6):537–547. doi: 10.1056/NEJMra1011165
   PubMed Web of Science ®Google Scholar
• Yu Y, He J, Liu W, et al. Molecular characterization and functional analysis of hypoxia-responsive factor prolyl hydroxylase domain 2 in mandarin fish (siniperca chuatsi. Animals-basel. 2023;13(9):1556. doi: 10.3390/ani13091556
   Web of Science ®Google Scholar
• Ward R, Ali Z, Slater K, et al. Pharmacological restoration of visual function in a zebrafish model of von-hippel Lindau disease. Dev Biol. 2020;457(2):226–234. doi: 10.1016/j.ydbio.2019.02.008
   PubMed Web of Science ®Google Scholar
• Rodriguez J, Pilkington R, Garcia MA, et al. Substrate-trapped interactors of PHD3 and FIH cluster in distinct signaling pathways. Cell Rep. 2016;14(11):2745–2760. doi: 10.1016/j.celrep.2016.02.043
   PubMed Web of Science ®Google Scholar
• Cai X, Zhang D, Wang J, et al. Deletion of the fih gene encoding an inhibitor of hypoxia-inducible factors increases hypoxia tolerance in zebrafish. J Biol Chem. 2018;293(40):15370–15380. doi: 10.1074/jbc.RA118.003004
   PubMed Web of Science ®Google Scholar
• Kondo S, Seo SY, Yoshizaki T, et al. EBV Latent Membrane Protein 1 Up-regulates hypoxia-Inducible factor 1α through siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells. Cancer Res. 2006;66(20):9870–9877. doi: 10.1158/0008-5472.CAN-06-1679
   PubMed Web of Science ®Google Scholar
• Moon EJ, Jeong CH, Jeong JW, et al. Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1α. FASEB J. 2004;18(2):1–16. doi: 10.1096/fj.03-0153fje
   PubMed Web of Science ®Google Scholar
• Ren L, Zhang W, Han P, et al. Influenza a virus (H1N1) triggers a hypoxic response by stabilizing hypoxia-inducible factor-1α via inhibition of proteasome. Virology. 2019;530:51–58. doi: 10.1016/j.virol.2019.02.010
   PubMed Web of Science ®Google Scholar
• Blanie S, Gelfi J, Bertagnoli S, et al. MNF, an ankyrin repeat protein of myxoma virus, is part of a native cellular SCF complex during viral infection. Virol J. 2010;7(1):56. doi: 10.1186/1743-422X-7-56
   PubMedGoogle Scholar
• Herbert MH, Squire CJ, Mercer AA. Poxviral ankyrin proteins. Viruses-Basel. 2015;7(2):709–738. doi: 10.3390/v7020709
   PubMed Web of Science ®Google Scholar
• Noel EA, Kang M, Adamec J, et al. Chlorovirus Skp1-binding ankyrin repeat protein interplay and mimicry of cellular ubiquitin ligase machinery. J Virol. 2014;88(23):13798–13810. doi: 10.1128/JVI.02109-14
   PubMed Web of Science ®Google Scholar
• Burles K, van Buuren N, Barry M. Ectromelia virus encodes a family of Ankyrin/F-box proteins that regulate NFκB. Virology. 2014;468-470:351–362. doi: 10.1016/j.virol.2014.08.030
   PubMed Web of Science ®Google Scholar
• Simon MC. Siah proteins, HIF prolyl hydroxylases, and the physiological response to hypoxia. Cell. 2004;117(7):851–853. doi: 10.1016/j.cell.2004.06.010
   PubMed Web of Science ®Google Scholar
• Gordon JE. Evolution of an epidemiology of health. Chapters 3, 4 and 5 in the epidemiology of health, vol. health education council. New York. 1953.
   Google Scholar
• Sooryanarain H, Elankumaran S. Environmental role in influenza virus outbreaks, Annu Rev Anim Biosci. Annu Rev Anim Biosci. 2015;3(1):347–373. doi: 10.1146/annurev-animal-022114-111017
   PubMed Web of Science ®Google Scholar