Effectiveness of booster BCG vaccination in preventing Covid-19 infection

References

• Berg MK, Yu Q, Salvador CE, Melani I, Kitayama S. Mandated Bacillus Calmette-Guérin (BCG) vaccination predicts flattened curves for the spread of COVID-19. Sci Adv. 2020 Aug 5;6(32):eabc1463. doi:10.1126/sciadv.abc1463. PMID:32923613; PMCID:PMC7457335.
   Google Scholar
• Miller A, Reandelar MJ, Fasciglione K, Roumenova V, Li Y, Otazu GH. Correlation between universal BCG vaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study. medRxiv. 2020;2020.03.24.20042937.
   Google Scholar
• Wardhana DEA, Sultana A, Mandang VV, Jim E. The efficacy of Bacillus Calmette-Guerin vaccinations for the prevention of acute upper respiratory tract infection in the elderly. Acta Med Indones. 2011;43:185–90.
   PubMedGoogle Scholar
• Lopez-Martin I, Andres Esteban E, Garcia-Martinez FJ. Relationship between MMR vaccination and severity of Covid-19 infection. Survey among primary care physicians. Med Clin (Engl Ed). 2021;156:140–41.
   PubMedGoogle Scholar
• Marakasova E, Baranova A. MMR vaccine and COVID-19: measles protein homology may contribute to cross-reactivity or to complement activation protection. mBio. 2021;12. doi:10.1128/mBio.03447-20.
   PubMed Web of Science ®Google Scholar
• Higgins J, Soares-Weiser K, Reingold A. Systematic review of the non-specific effects of BCG, DTP and measles containing vaccines. WHO Rt, ed. Report to WHO Report to WHO 2014.
   Google Scholar
• Leentjens J, Kox M, Stokman R, Gerretsen J, Diavatopoulos DA, Van Crevel R, Rimmelzwaan GF, Pickkers P, Netea MG. BCG vaccination enhances the immunogenicity of subsequent influenza vaccination in healthy volunteers: a randomized, placebo-controlled pilot study. J Infect Dis. 2015;212:1930–38. doi:10.1093/infdis/jiv332.
   PubMed Web of Science ®Google Scholar
• Higgins JP, Soares-Weiser K, Lopez-Lopez JA, Kakourou A, Chaplin K, Christensen H, Martin NK, Sterne JAC, Reingold AL. Association of BCG, DTP, and measles containing vaccines with childhood mortality: systematic review. BMJ. 2016;355:i5170. doi:10.1136/bmj.i5170.
   PubMed Web of Science ®Google Scholar
• Netea MG, Van Crevel R. BCG-induced protection: effects on innate immune memory. Semin Immunol. 2014;26:512–17. doi:10.1016/j.smim.2014.09.006.
   PubMed Web of Science ®Google Scholar
• Gupta N, Garg S, Vedi S, Kunimoto DY, Kumar R, Agrawal B. Future path toward TB vaccine development: boosting BCG or re-educating by a new subunit vaccine. Front Immunol. 2018;9:2371. doi:10.3389/fimmu.2018.02371.
   PubMed Web of Science ®Google Scholar
• Whittaker E, Nicol MP, Zar HJ, Tena-Coki NG, Kampmann B. Age-related waning of immune responses to BCG in healthy children supports the need for a booster dose of BCG in TB endemic countries. Sci Rep. 2018;8:15309. doi:10.1038/s41598-018-33499-4.
   PubMed Web of Science ®Google Scholar
• Kelleni MT. BCG vaccination potential for COVID-19: an analytical approach. Hum Vaccin Immunother. 2021;1–3. doi:10.1080/21645515.2021.1885281.
   Web of Science ®Google Scholar
• Gonzalez-Perez M, Sanchez-Tarjuelo R, Shor B, Nistal-Villan E, Ochando J. The BCG vaccine for COVID-19: first verdict and future directions. Front Immunol. 2021;12:632478. doi:10.3389/fimmu.2021.632478.
   PubMed Web of Science ®Google Scholar
• Koneru G, Batiha GE, Algammal AM, Mabrok M, Magdy S, Sayed S, AbuElmagd ME, Elnemr R, Saad MM, Abd Ellah NH, et al. BCG vaccine-induced trained immunity and COVID-19: protective or bystander? Infect Drug Resist. 2021;14:1169–84. doi:10.2147/IDR.S300162.
   PubMed Web of Science ®Google Scholar
• Escobar LE, Molina-Cruz A, Barillas-Mury C. BCG vaccine protection from severe coronavirus disease 2019 (COVID-19). Proc Natl Acad Sci. 2020;117:17720–17726.
   Web of Science ®Google Scholar
• Netea MG, van der Meer JW, Van Crevel R. BCG vaccination in health care providers and the protection against COVID-19. J Clin Invest. 2021;131:e145545. doi:10.1172/JCI145545
   Web of Science ®Google Scholar
• Rivas MN, Ebinger JE, Wu M, Sun N, Braun J, Sobhani K, Van Eyk JE, Cheng S, Arditi M. BCG vaccination history associates with decreased SARS-CoV-2 seroprevalence across a diverse cohort of health care workers. J Clin Invest. 2021;131:e145157. doi:10.1172/JCI145157.
   Web of Science ®Google Scholar
• Zwerling A, Behr MA, Verma A, Brewer TF, Menzies D, Pai M. The BCG World Atlas: a database of global BCG vaccination policies and practices. PLoS Med. 2011;8:e1001012. doi:10.1371/journal.pmed.1001012.
   PubMed Web of Science ®Google Scholar
• BCG vaccines: WHO position.
   Google Scholar