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Research Paper

Defining the volume of rabies immunoglobulins/ rabies monoclonal antibodies requirement for wound infiltration of category III animal exposures – an exploratory study

, ORCID Icon, , , ORCID Icon & ORCID Icon
Pages 5355-5360 | Received 03 Sep 2021, Accepted 26 Nov 2021, Published online: 21 Jan 2022

References

  • Weekly Epidemiological Record. Rabies Vaccines: WHO Position Paper No 16. World Health Organization; 2018. Vol. 93, p. 201–20.
  • Tarantola A. Four thousand years of concepts relating to rabies in animals and humans, its prevention and its cure. Trop Med Infect Dis. 2017; 2:E5. doi:10.3390/tropicalmed2020005.
  • World Health Organization. WHO South East Asia region strategic framework for elimination of human rabies transmitted by dogs in the South-East Asia region. Geneva (Switzerland): World Health Organization, Regional office for South East Asia; 2012.
  • Wilde H, Khawplod P, Khamoltham T, Hemachudha T, Tepsumethanon V, Lumlerdacha B, et al., Rabies control in South and Southeast Asia. Vaccine. 2005;23:2284–89. doi:10.1016/j.vaccine.2005.01.030.
  • Gongal G. Introduction of intradermal rabies vaccination–a paradigm shift in improving post-exposure prophylaxis in Asia. Vaccine. 2018;37(1):94–98. doi:10.1016/j.vaccine.2018.08.034.
  • World Health Organisation, Geneva. Zero by 30: the global strategic plan to end human deaths from dog mediated rabies by 2030. Geneva (Switzerland): Food and Agriculture Organization of the United Nations, World Organisation for Animal Health, World Health Organization and Global Alliance for Rabies Control; 2018.
  • National guidelines for rabies prophylaxis 2019, National rabies control programme. National centre for diseases control. New Delhi (India): National Centre for Disease Control; 2019. p. 6–18.
  • World Health Organization. WHO expert consultation on rabies. Geneva (Switzerland): World Health Organization; 2018. 3rd Report, Technical Report Series 1012.
  • Sudarshan MK, Ravish HS. Facilities and services of post exposure prophylaxis in anti rabies clinics: a national assessment in India. Indian J Public Health. 2019;63(1):s26–30. doi:10.4103/ijph.IJPH_367_19.
  • Bharti OK, Madhusudana SN, Gaunta PL, Belludi AY. Local infiltration of rabies immunoglobulins without systemic intramuscular administration: an alternative cost-effective approach for passive immunization against rabies. Hum Vaccin Immunother. 2016;12(3):837–42. doi:10.1080/21645515.2015.1085142.
  • Ichhpujani RL, Mala C, Veena M, Singh J, Bhardwaj M, Bhattacharya D, et al. Epidemiology of animal bites and rabies cases in India. A multicentric study. J Commun Dis. 2008;40:27–36.
  • Ashwath Narayana DH, Ravish HS, Ramesh H. Clinical evaluation of safety of equine rabies immunoglobulin. APCRI J. 2011;12:12–15.
  • Kim PK, Keum SJ, Osinubi MOV, Franka R, Shin JY, Park ST, et al, et al. Development and characterization of novel chimeric monoclonal antibodies for broad spectrum neutralization of rabies virus. PLoS ONE. 2017;12(10):e0186380. doi:10.1371/journal.pone.0186380.
  • Gogtay NJ, Munshi R, Ashwath Narayana DH, Mahendra BJ, Kshirsagar V, Gunale B, et al, et al. Comparison of a novel human rabies monoclonal antibody to human rabies immunoglobulin for post-exposure prophylaxis: a phase 2/3 randomized, single blind, non-inferiority, controlled study. Clin Infect Dis. 2018;66(3):387–95. doi:10.1093/cid/cix791.
  • Habel K, Koprowski H. Laboratory data supporting the clinical trial of anti-rabies serum in persons bitten by a rabid wolf. Bull World Health Organ. 1955;13:773–79.
  • Hobart-Porter N, Stein M, Toh N, Amega N, Nguyen H-B, Linakis J. Safety and efficacy of rabies immunoglobulin in pediatric patients with suspected exposure. Hum Vaccin Immunother. 2021;17:7, 2090–96. doi:10.1080/21645515.2020.1854000.
  • Ravish H, Krishna C, Kumar P, Siddareddy I, Annadani R. Safety, immunogenicity and clinical efficacy of post exposure prophylaxis in confirmed rabies exposures. Global Vaccines Immunol. 2016;1:56–59. doi:10.15761/GVI.1000116.
  • Dean DJ, Bear GM, Thompson WR. Studies on the local treatment of rabies infected wounds. Bull World Health Organ. 1963;28:477–84.
  • Madhusudana SN, Ashwin BY, Sudarshan S. Feasibility of reducing rabies immunoglobulin dosage for passive immunization against rabies: results of In vitro and In vivo studies. Hum Vaccin Immunother. 2013;9(9):1914–17. doi:10.4161/hv.25431.
  • Bharti OK, Madhusudana SN, Wilde H. Injecting rabies immunoglobulin (RIG) into wounds only: a significant saving of lives and costly RIG. Hum Vaccin Immunother. 2017;13(4):762–65. doi:10.1080/21645515.2016.1255834.
  • Bharti OK, Thakur B, Rao R. Wound-only injection of rabies immunoglobulin (RIG) saves lives and costs less than a dollar per patient by “pooling strategy.” Vaccine. 2019;37:A128–A131. doi:10.1016/j.vaccine.2019.07.087.
  • Haradanhalli RS, Anwith HS, Pradeep BS, Isloor S, Bilagumba G. Health-seeking behavior and compliance to post exposure prophylaxis among animal bite victims in India. Indian J Public Health. 2019;63:S20–5. doi:10.4103/ijph.IJPH_364_19.
  • Sangeetha S, Sujatha K, William RF. An epidemiological study of animal bites among rural population in Tamil Nadu, India. Int J Community Med Public Health. 2016;3:1413–18. doi:10.18203/2394-6040.ijcmph20161603.
  • Park JW, Kim DK, Jung JY, Lee SU, Chang I, Kwak YH, et al. Dog-bite injuries in Korea and risk factors for significant dog-bite injuries: a 6-year cross-sectional study. PLoS ONE. 2019;14(2):e0210541. doi:10.1371/journal.pone.0210541.
  • Sudarshan MK, Madhusudana SN, Mahendra BJ, Rao NS, Ashwath Narayana DH, Abdul Rahman S, et al. Assessing the burden of human rabies in India: results of a national multi-center epidemiological survey. Int J Infect Dis. 2007;11(1):29–35. doi:10.1016/j.ijid.2005.10.007.
  • Ravish HS, Kumari N, Ramya MP, Surendran J. Safety of rabies immunoglobulin (RIG)/ rabies monoclonal antibody (RMAb) for post-exposure prophylaxis in patients with potential rabies exposure. APCRI J. 2019;21:22–27.
  • World Health Organization. New global strategic plan to eliminate dog-mediated rabies by 2030. Geneva (Switzerland): World Health Organization; 2018.
  • Universal health Coverage. Geneva (Switzerland): World Health Organization. [accessed 2021 Aug 23]. https://www.who.int/news-room/fact-sheets/detail/universal-health-coverage-(uhc).