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Research Article

Sputum pathogen spectrum and clinical outcomes of upper respiratory tract infection in bronchiectasis exacerbation: a prospective cohort study

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Article: 2202277 | Received 11 Oct 2022, Accepted 07 Apr 2023, Published online: 08 May 2023

References

  • Chang AB, Fortescue R, Grimwood K, et al. European respiratory society guidelines for the management of children and adolescents with bronchiectasis. Eur Respir J. 2021;58(2):2002990.
  • Kapur N, Masters IB, Chang AB. Exacerbations in noncystic fibrosis bronchiectasis: clinical features and investigations. Respir Med. 2009;103(11):1681–1687.
  • Chalmers JD, Aliberti S, Filonenko A, et al. Characterization of the “frequent exacerbator phenotype” in bronchiectasis. Am J Respir Crit Care Med. 2018;197(11):1410–1420.
  • Mac Aogain M, Narayana JK, Tiew PY, et al. Integrative microbiomics in bronchiectasis exacerbations. Nat Med. 2021;27(4):688–699.
  • Dicker AJ, Lonergan M, Keir HR, et al. The sputum microbiome and clinical outcomes in patients with bronchiectasis: a prospective observational study. Lancet Respir Med. 2021;9(8):885–896.
  • Guan WJ, Gao YH, Xu G, et al. Sputum bacteriology in steady-state bronchiectasis in Guangzhou, China. Int J Tuberc Lung Dis. 2015;19(5):610–619.
  • Martinez-García MA. Pseudomonas aeruginosa infection and exacerbations in bronchiectasis: more questions than answers. Eur Respir J. 2018;51(2):1702497.
  • Hurst JR, Donaldson GC, Wilkinson TM, et al. Epidemiological relationships between the common cold and exacerbation frequency in COPD. Eur Respir J. 2005;26(5):846–852.
  • Johnston NW, Olsson M, Edsbacker S, et al. Colds as predictors of the onset and severity of COPD exacerbations. Int J Chron Obstruct Pulmon Dis. 2017;12:839–848.
  • Heikkinen T, Järvinen A. The common cold. Lancet. 2003;361(9351):51–59.
  • Arroll B. Common cold. BMJ Clin Evid. 2011;2011:1510.
  • Wiselka MJ, Kent J, Cookson JB, et al. Impact of respiratory virus infection in patients with chronic chest disease. Epidemiol Infect. 1993;111(2):337–346.
  • Jackson DJ, Gern JE. Rhinovirus infections and their roles in asthma: etiology and exacerbations. J Allergy Clin Immunol Pract. 2022;10(3):673–681.
  • Ortega H, Nickle D, Carter L. Rhinovirus and asthma: challenges and opportunities. Rev Med Virol. 2021;31(4):e2193.
  • Yang M, Zhang Y, Chen H, et al. Inhaled corticosteroids and risk of upper respiratory tract infection in patients with asthma: a meta-analysis. Infection. 2019;47(3):377–385.
  • Chen CL, Huang Y, Yuan JJ, et al. The roles of bacteria and viruses in bronchiectasis exacerbation: A prospective study. Arch Bronconeumol. 2020;56(10):621–629.
  • Reiff DB, Wells AU, Carr DH, et al. CT findings in bronchiectasis: limited value in distinguishing between idiopathic and specific types. AJR Am J Roentgenol. 1995;165(2):261–267.
  • Gao YH, Guan WJ, Xu G, et al. The role of viral infection in pulmonary exacerbations of bronchiectasis in adults: a prospective study. Chest. 2015;147(6):1635–1643.
  • Hill AT, Haworth CS, Aliberti S, et al. Pulmonary exacerbation in adults with bronchiectasis: a consensus definition for clinical research. Eur Respir J. 2017;49(6):1700051.
  • Chalmers JD, Haworth CS, Metersky ML, et al. Phase 2 trial of the DPP-1 inhibitor brensocatib in bronchiectasis. N Engl J Med. 2020;383(22):2127–2137.
  • Dransfield MT, Voelker H, Bhatt SP, et al. Metoprolol for the prevention of acute exacerbations of COPD. N Engl J Med. 2019;381(24):2304–2314.
  • Stolz D, Papakonstantinou E, Grize L, et al. Time-course of upper respiratory tract viral infection and COPD exacerbation. Eur Respir J. 2019;54(4):1900407.
  • Artaraz A, Crichton ML, Finch S, et al. Development and initial validation of the bronchiectasis exacerbation and symptom tool (BEST). Respir Res. 2020;21(1):18.
  • Finch S, Laska IF, Abo-Leyah H, et al. Validation of the COPD assessment test (CAT) as an outcome measure in bronchiectasis. Chest. 2020;157(4):815–823.
  • Leidy NK, Murray LT, Monz BU, et al. Measuring respiratory symptoms of COPD: performance of the EXACT-respiratory symptoms tool (E-RS) in three clinical trials. Respir Res. 2014;15(1):124.
  • Murray PR, Washington JA. Microscopic and baceriologic analysis of expectorated sputum. Mayo Clin Proc. 1975;50(6):339–344.
  • Kardos P, Malek FA. Common cold – an umbrella term for acute infections of nose, throat, larynx and bronchi. Pneumologie. 2017;71(4):221–226.
  • Molyneaux PL, Mallia P, Cox MJ, et al. Outgrowth of the bacterial airway microbiome after rhinovirus exacerbation of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2013;188(10):1224–1231.
  • Gao YH, Guan WJ, Zhu YN, et al. Respiratory pathogen spectrum in pulmonary exacerbation of bronchiectasis in adults and its association with disease severity. Zhonghua Jie He He Hu Xi Za Zhi. 2019;42(4):254–261.
  • Kapur N, Mackay IM, Sloots TP, et al. Respiratory viruses in exacerbations of non-cystic fibrosis bronchiectasis in children. Arch Dis Child. 2014;99(8):749–753.
  • Park YE, Sung H, Oh YM. Respiratory viruses in acute exacerbations of bronchiectasis. J Korean Med Sci. 2021;36(34):e217.
  • Coverstone AM, Wilson B, Burgdorf D, et al. Recurrent wheezing in children following human metapneumovirus infection. J Allergy Clin Immunol. 2018;142(1):297–301.e2.
  • Rohde G, Borg I, Arinir U, et al. Relevance of human metapneumovirus in exacerbations of COPD. Respir Res. 2005;6(1):150.
  • Daubin C, Parienti JJ, Vincent S, et al. Epidemiology and clinical outcome of virus-positive respiratory samples in ventilated patients: a prospective cohort study. Crit Care. 2006;10(5):R142.
  • McManus T, Marley A, Baxter N, et al. Herpes simplex virus and mortality in COPD. Am J Respir Crit Care Med. 2009;179:A5348.
  • Bruynseels P, Jorens PG, Demey HE, et al. Herpes simplex virus in the respiratory tract of critical care patients: a prospective study. Lancet. 2003;362(9395):1536–1541.
  • Luyt CE, Combes A, Deback C, et al. Herpes simplex virus lung infection in patients undergoing prolonged mechanical ventilation. Am J Respir Crit Care Med. 2007;175(9):935–942.
  • Jacobs SE, Lamson DM, St George K, et al. Human rhinoviruses. Clin Microbiol Rev. 2013;26(1):135–162.
  • Hutchinson EC. Influenza virus. Trends Microbiol. 2018;26(9):809–810.
  • Tang BM, Shojaei M, Parnell GP, et al. A novel immune biomarker IFI27 discriminates between influenza and bacteria in patients with suspected respiratory infection. Eur Respir J. 2017;49(6):1602098.
  • Turner RB, Fuls JL, Rodgers ND, et al. A randomized trial of the efficacy of hand disinfection for prevention of rhinovirus infection. Clin Infect Dis. 2012;54(10):1422–1426.