Rift Valley fever virus modulates apoptosis and immune response during infection of human astrocytes

References

• Venter M. Assessing the zoonotic potential of arboviruses of African origin. Curr Opin Virol. 2018;28:74–84.
   PubMed Web of Science ®Google Scholar
• Carlson CJ, Albery GF, Merow C, et al. Climate change increases cross-species viral transmission risk. Nature. 2022;607:555–562.
   PubMed Web of Science ®Google Scholar
• Muñoz LS, Garcia MA, Gordon-Lipkin E, et al. Emerging viral infections and their impact on the global burden of neurological disease. Semin Neurol. 2018;38:163–175.
   PubMed Web of Science ®Google Scholar
• Daubney R, Hudson JR. Enzootic hepatitis or rift valley fever. An un-described virus disease of sheep, cattle and man from east Africa. J Pathol Bacteriol. 1931;34:545–579.
   Google Scholar
• Adams MJ, Lefkowitz EJ, King AMQQ, et al. Changes to taxonomy and the international code of virus classification and nomenclature ratified by the international committee on taxonomy of viruses (2017). Arch Virol. 2017;162:2505–2538.
   PubMed Web of Science ®Google Scholar
• McMillen CM, Hartman AL. Rift valley fever in animals and humans: current perspectives. Antiviral Res. 2018;156:29–37.
   PubMed Web of Science ®Google Scholar
• Wright D, Kortekaas J, Bowden TA, et al. Rift Valley fever: biology and epidemiology. J Gen Virol. 2019;100:1187–1199.
   PubMed Web of Science ®Google Scholar
• Métras R, John Edmunds W, Youssouffi C, et al. Estimation of Rift Valley fever virus spillover to humans during the Mayotte 2018-2019 epidemic. PNAS. 2020;117:24567–24574.
   PubMed Web of Science ®Google Scholar
• Javelle E, Lesueur A, de Santi V P, et al. The challenging management of Rift Valley fever in humans: literature review of the clinical disease and algorithm proposal. Ann Clin Microbiol Antimicrob. 2020;19:4.
   PubMed Web of Science ®Google Scholar
• Ikegami T, Makino S. The pathogenesis of Rift Valley fever. Viruses. 2011;3:493–519.
   PubMed Web of Science ®Google Scholar
• Mohamed M, Mosha F, Mghamba J, et al. Epidemiologic and clinical aspects of a rift valley fever outbreak in humans in Tanzania, 2007. Am J Trop Med Hyg. 2010;83:22–27.
   PubMed Web of Science ®Google Scholar
• Anywaine Z, Lule SA, Hansen C, et al. Clinical manifestations of Rift Valley fever in humans: systematic review and meta-analysis. PLoS Negl Trop Dis. 2022;16:e0010233.
   PubMed Web of Science ®Google Scholar
• van Velden DJ, Meyer J, Olivier J, et al. Rift Valley fever affecting humans in South Africa: a clinicopathological study. S Afr Med J. 1977;51:867–871.
   PubMed Web of Science ®Google Scholar
• Hartman AL, Powell DS, Bethel LM, et al. Aerosolized Rift Valley fever virus causes fatal encephalitis in African green monkeys and common marmosets. J Virol. 2014;88:2235–2245.
   PubMed Web of Science ®Google Scholar
• Smith DR, Steele KE, Shamblin J, et al. The pathogenesis of Rift Valley fever virus in the mouse model. Virology. 2010;407:256–267.
   PubMed Web of Science ®Google Scholar
• Odendaal L, Davis AS, Venter EH. Insights into the pathogenesis of viral haemorrhagic fever based on virus tropism and tissue lesions of natural Rift Valley fever. Viruses. 2021;13:709.
   PubMed Web of Science ®Google Scholar
• Reed C, Steele KE, Honko A, et al. Ultrastructural study of Rift Valley fever virus in the mouse model. Virology. 2012;431:58–70.
   PubMed Web of Science ®Google Scholar
• Weilhammer DR. Investigating the role of innate immunity in viral encephalitis caused by Rift Valley fever virus; Lawrence Livermore National Laboratory. LLNL-TR-795766. 2019;1–9.
   Google Scholar
• Gommet C, Billecocq A, Jouvion G, et al. Tissue tropism and target cells of NSs-deleted rift valley fever virus in live immunodeficient mice. PLoS Negl Trop Dis. 2011;5:e1421.
   PubMed Web of Science ®Google Scholar
• do Valle TZ, Billecocq A, Guillemot L, et al. A new mouse model reveals a critical role for host innate immunity in resistance to Rift Valley fever. J Immunol. 2010;185:6146–6156.
   PubMed Web of Science ®Google Scholar
• Gray KK, Worthy MN, Juelich TL, et al. Chemotactic and inflammatory responses in the liver and brain are associated with pathogenesis of rift valley fever virus infection in the mouse. PLoS Negl Trop Dis. 2012;6(2):e1529.
   PubMed Web of Science ®Google Scholar
• Dodd KA, McElroy AK, Jones TL, et al. Rift Valley fever virus encephalitis Is associated with an ineffective systemic immune response and activated T cell infiltration into the CNS in an immunocompetent mouse model. PLoS Negl Trop Dis. 2014;8(6):e2874.
   PubMed Web of Science ®Google Scholar
• Albe JR, Boyles DA, Walters AW, et al. Neutrophil and macrophage influx into the central nervous system are inflammatory components of lethal Rift Valley fever encephalitis in rats. PLoS Pathog. 2019;15:e1007833.
   PubMed Web of Science ®Google Scholar
• Walters AW, Kujawa MR, Albe JR, et al. Vascular permeability in the brain is a late pathogenic event during Rift Valley fever virus encephalitis in rats. Virology. 2019;526:173–179.
   PubMed Web of Science ®Google Scholar
• Dodd KA, McElroy AK, Jones MEB, et al. Rift Valley fever virus clearance and protection from neurologic disease Are dependent on CD4 + T cell and virus-specific antibody responses. J Virol. 2013;87:6161–6171.
   PubMed Web of Science ®Google Scholar
• Bird BH, McElroy AK. Rift Valley fever virus: unanswered questions. Antiviral Res. 2016;132:274–280.
   PubMed Web of Science ®Google Scholar
• Connors KA, Hartman AL. Advances in understanding neuropathogenesis of Rift Valley fever virus. Annu Rev Virol. 2022;9:437–450.
   PubMed Web of Science ®Google Scholar
• Jensen CJ, Massie A, De Keyser J. Immune players in the CNS: the astrocyte. J Neuroimmune Pharmacol. 2013;8:824–839.
   PubMed Web of Science ®Google Scholar
• Ly HJ, Ikegami T. Rift Valley fever virus NSs protein functions and the similarity to other bunyavirus NSs proteins. Virol J. 2016;13:118.
   PubMed Web of Science ®Google Scholar
• Mamy AB E, Lo MM, Thiongane Y, et al. Comprehensive phylogenetic reconstructions of Rift Valley fever virus: the 2010 northern Mauritania outbreak in the Camelus dromedarius species. Vector Borne Zoonotic Dis. 2014;14:856–861.
   PubMed Web of Science ®Google Scholar
• Cêtre-Sossah C, Zeller H, Grandadam M, et al. Genome analysis of Rift Valley fever virus, Mayotte. Emerg Infect Dis. 2012;18:969–971.
   PubMed Web of Science ®Google Scholar
• Muller R, Saluzzo JF, Lopez N, et al. Characterization of clone 13, a naturally attenuated avirulent isolate of Rift Valley fever virus, which is altered in the small segment. Am J Trop Med Hyg. 1995 [cited 2022 Dec 5];53:405–411.
   PubMed Web of Science ®Google Scholar
• Reed LJ, Muench H. A simple method of estimating fifty percent endpoints. Am J Epidemiol. 1938;27:493–497.
   Google Scholar
• Ketelut-Carneiro N, Fitzgerald KA. Apoptosis, pyroptosis, and necroptosis – Oh My! The many ways a cell Can Die. J. Mol. Biol. 2022;434:167378.
   PubMed Web of Science ®Google Scholar
• Yadani F-Z, Kohl A, Préhaud C, et al. The carboxy-terminal acidic domain of Rift Valley fever virus NSs protein Is essential for the formation of filamentous structures but Not for the nuclear localization of the protein. J Virol. 1999;73:5018–5025.
   PubMed Web of Science ®Google Scholar
• Shin JH, Kim SW, Lim CM, et al. αB-crystallin suppresses oxidative stress-induced astrocyte apoptosis by inhibiting caspase-3 activation. Neurosci Res. 2009;64:355–361.
   PubMed Web of Science ®Google Scholar
• Clé M, Eldin P, Briant L, et al. Neurocognitive impacts of arbovirus infections. J Neuroinflammation. 2020;17:233.
   PubMed Web of Science ®Google Scholar
• Soung A, Klein RS. Viral encephalitis and neurologic diseases: focus on astrocytes. Trends Mol Med. 2018;24:950–962.
   PubMed Web of Science ®Google Scholar
• De Keyser J, Mostert JP, Koch MW. Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders. J Neurol Sci. 2008;267:3–16.
   PubMed Web of Science ®Google Scholar
• Lee H-G, Wheeler MA, Quintana FJ. Function and therapeutic value of astrocytes in neurological diseases. 2022;21:339–358.
   Google Scholar
• Baer A, Austin D, Narayanan A, et al. Induction of DNA damage signaling upon Rift Valley fever virus infection results in cell cycle arrest and increased viral replication. J Biol Chem. 2012;287:7399–7410.
   PubMed Web of Science ®Google Scholar
• Won S, Ikegami T, Peters CJ, et al. NSm protein of Rift Valley fever virus suppresses virus-induced apoptosis. J Virol. 2007;81:13335–13345.
   PubMed Web of Science ®Google Scholar
• Terasaki K, Won S, Makino S. The C-terminal region of Rift Valley fever virus NSm protein targets the protein to the mitochondrial outer membrane and exerts antiapoptotic function. J Virol. 2013 [cited 2022 Dec 20];87:676–682.
   PubMed Web of Science ®Google Scholar
• Michaely LM, Rissmann M, Armando F, et al. Rift Valley fever virus Non-structural protein S is associated with nuclear translocation of active caspase-3 and inclusion body formation. Viruses. 2022;14:2487.
   Google Scholar
• Hum NR, Bourguet FA, Sebastian A, et al. MAVS mediates a protective immune response in the brain to Rift Valley fever virus. PLoS Pathog. 2022;18:1–28.
   Web of Science ®Google Scholar
• Wuerth JD, Weber F. Phleboviruses and the type I interferon response. Viruses. 2016;8:174.
   PubMed Web of Science ®Google Scholar
• Le May N, Dubaele S, De Santis L P, et al. TFIIH transcription factor, a target for the Rift Valley hemorrhagic fever virus viremia, and leads to miscarriage in pregnant animals, resulting in economic disaster in African countries. RVFV possesses a single-stranded segmented RNA genome. Cell. 2004;116:541–550.
   PubMed Web of Science ®Google Scholar
• van Vuren P J, Tiemessen CT, Paweska JT. Anti-nucleocapsid protein immune responses counteract pathogenic effects of Rift Valley fever virus infection in mice. PLoS One. 2011;6(9):e25027.
   PubMed Web of Science ®Google Scholar
• Copeland AM, van Deusen NM, Schmaljohn CS. Rift Valley fever virus NSS gene expression correlates with a defect in nuclear mRNA export. Virology. 2015;486:88–93.
   PubMed Web of Science ®Google Scholar
• Léger P, Nachman E, Richter K, et al. NSs amyloid formation is associated with the virulence of Rift Valley fever virus in mice. Nat Commun. 2020;11:3281.
   PubMed Web of Science ®Google Scholar
• Hise AG, Traylor Z, Hall NB, et al. Association of symptoms and severity of rift valley fever with genetic polymorphisms in human innate immune pathways. PLoS Negl Trop Dis. 2015;9:e0003584.
   PubMed Web of Science ®Google Scholar
• Wonderlich ER, Caroline AL, McMillen CM, et al. Peripheral blood biomarkers of disease outcome in a monkey model of Rift Valley fever encephalitis. J Virol. 2018;92: e01662-17.
   PubMed Web of Science ®Google Scholar
• Vuren PVJ, Shalekoff S, Grobbelaar AA, et al. Serum levels of inflammatory cytokines in Rift Valley fever patients are indicative of severe disease. Virol J. 2015;12:159.
   PubMed Web of Science ®Google Scholar
• Njenga MK, Paweska J, Wanjala R, et al. Using a field quantitative real-time PCR test to rapidly identify highly viremic rift valley fever cases. J Clin Microbiol. 2009;47:1166–1171.
   PubMed Web of Science ®Google Scholar
• McElroy AK, Nichol ST. Rift Valley fever virus inhibits a pro-inflammatory response in experimentally infected human monocyte derived macrophages and a pro-inflammatory cytokine response may be associated with patient survival during natural infection. Virology. 2012;422:6–12.
   PubMed Web of Science ®Google Scholar