Evolution and biological characterization of H5N1 influenza viruses bearing the clade 2.3.2.1 hemagglutinin gene

References

• Tong S, Li Y, Rivailler P, et al. A distinct lineage of influenza A virus from bats. Proc Natl Acad Sci U S A. 2012;109(11):4269–4274. doi:10.1073/pnas.1116200109
   PubMed Web of Science ®Google Scholar
• Tong S, Zhu X, Li Y, et al. New world bats harbor diverse influenza A viruses. PLoS Pathog. 2013;9(10):e1003657, doi:10.1371/journal.ppat.1003657
   PubMed Web of Science ®Google Scholar
• Alexander DJ, Brown IH. History of highly pathogenic avian influenza. Rev Sci Tech. 2009;28(1):19–38. doi:10.20506/rst.28.1.1856
   PubMed Web of Science ®Google Scholar
• Kobayashi Y, Horimoto T, Kawaoka Y, et al. Pathological studies of chickens experimentally infected with two highly pathogenic avian influenza viruses. Avian Pathol. 1996;25(2):285–304. doi:10.1080/03079459608419142
   PubMed Web of Science ®Google Scholar
• Xu X, Subbarao K, Cox NJ, et al. Genetic characterization of the pathogenic influenza A/Goose/Guangdong/1/96 (H5N1) virus: similarity of its hemagglutinin gene to those of H5N1 viruses from the 1997 outbreaks in Hong Kong. Virology. 1999;261(1):15–19. doi:10.1006/viro.1999.9820
   PubMed Web of Science ®Google Scholar
• Chen H, Deng G, Li Z, et al. The evolution of H5N1 influenza viruses in ducks in southern China. Proc Natl Acad Sci U S A. 2004;101(28):10452–10457. doi:10.1073/pnas.0403212101
   PubMed Web of Science ®Google Scholar
• Chen H. H5N1 avian influenza in China. Sci China C Life Sci. 2009;52(5):419–427. doi:10.1007/s11427-009-0068-6
   PubMedGoogle Scholar
• Cui P, Zeng X, Li X, et al. Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China. Sci China Life Sci. 2022;65(4):795–808. doi:10.1007/s11427-021-2025-y
   PubMed Web of Science ®Google Scholar
• Cui P, Shi J, Wang C, et al. Global dissemination of H5N1 influenza viruses bearing the clade 2.3.4.4b HA gene and biologic analysis of the ones detected in China. Emerg Microbes Infect. 2022;11(1):1693–1704. doi:10.1080/22221751.2022.2088407
   PubMed Web of Science ®Google Scholar
• WHO/FAO/OIE. Toward a unified nomenclature system for highly pathogenic avian influenza virus (H5N1). Emerg Infect Dis. 2008;14(7):e1, doi:10.3201/eid1407.071681
   PubMed Web of Science ®Google Scholar
• WHO. Antigenic and genetic characteristics of zoonotic influenza A viruses and development of candidate vaccine viruses for pandemic preparedness. Wkly Epidemiol Rec. 2020;95(44):525–539.
   Google Scholar
• Uchida Y, Mase M, Yoneda K, et al. Highly pathogenic avian influenza virus (H5N1) isolated from whooper swans, Japan. Emerg Infect Dis. 2008;14(9):1427–1429. doi:10.3201/eid1409.080655
   PubMed Web of Science ®Google Scholar
• Kang HM, Batchuluun D, Kim MC, et al. Genetic analyses of H5N1 avian influenza virus in Mongolia, 2009 and its relationship with those of Eastern Asia. Vet Microbiol. 2011;147(1-2):170–175. doi:10.1016/j.vetmic.2010.05.045
   PubMed Web of Science ®Google Scholar
• Li Y, Liu L, Zhang Y, et al. New avian influenza virus (H5N1) in wild birds, Qinghai, China. Emerg Infect Dis. 2011;17(2):265–267. doi:10.3201/eid1702.100732
   PubMed Web of Science ®Google Scholar
• Marinova-Petkova A, Georgiev G, Seiler P, et al. Spread of influenza virus A (H5N1) clade 2.3.2.1 to Bulgaria in common buzzards. Emerg Infect Dis. 2012;18(10):1596–602. doi:10.3201/eid1810.120357
   PubMed Web of Science ®Google Scholar
• Kim HR, Lee YJ, Park CK, et al. Highly pathogenic avian influenza (H5N1) outbreaks in wild birds and poultry, South Korea. Emerg Infect Dis. 2012;18(3):480–483. doi:10.3201/1803.111490
   PubMed Web of Science ®Google Scholar
• Naguib MM, Kinne J, Chen H, et al. Outbreaks of highly pathogenic avian influenza H5N1 clade 2.3.2.1c in hunting falcons and kept wild birds in Dubai implicate intercontinental virus spread. J Gen Virol. 2015;96(11):3212–3222. doi:10.1099/jgv.0.000274
   PubMedGoogle Scholar
• Nagarajan S, Tosh C, Smith DK, et al. Avian influenza (H5N1) virus of clade 2.3.2 in domestic poultry in India. PLoS One. 2012;7(2):e31844, doi:10.1371/journal.pone.0031844
   PubMed Web of Science ®Google Scholar
• Marinova-Petkova A, Feeroz MM, Rabiul Alam SM, et al. Multiple introductions of highly pathogenic avian influenza H5N1 viruses into Bangladesh. Emerg Microbes Infect. 2014;3(2):e11. doi:10.1038/emi.2014.11
   PubMed Web of Science ®Google Scholar
• Li C, Bu Z, Chen H. Avian influenza vaccines against H5N1 ‘bird flu’. Trends Biotechnol. 2014;32(3):147–156. doi:10.1016/j.tibtech.2014.01.001
   PubMed Web of Science ®Google Scholar
• Zeng X, Chen P, Liu L, et al. Protective efficacy of an H5N1 inactivated vaccine against challenge with lethal H5N1, H5N2, H5N6, and H5N8 influenza viruses in chickens. Avian Dis. 2016;60(1 Suppl):253–255. doi:10.1637/11179-052015-ResNoteR
   PubMed Web of Science ®Google Scholar
• Zeng X, Deng G, Liu L, et al. Protective efficacy of the inactivated H5N1 influenza vaccine Re-6 against different clades of H5N1 viruses isolated in China and the democratic People's Republic of Korea. Avian Dis. 2016;60(1 Suppl):238–240. doi:10.1637/11178-051915-ResNote
   PubMed Web of Science ®Google Scholar
• Zeng X, Chen X, Wu J, et al. Protective efficacy of an H5/H7 trivalent inactivated vaccine produced from Re-11, Re-12, and H7-Re2 strains against challenge with different H5 and H7 viruses in chickens. Journal of Integrative Agriculture. 2020;19(9):2294–2300. doi:10.1016/S2095-3119(20)63301-9
   Web of Science ®Google Scholar
• Zeng X, He X, Meng F, et al. Protective efficacy of an H5/H7 trivalent inactivated vaccine (H5-Re13, H5-Re14, and H7-Re4 strains) in chickens, ducks, and geese against newly detected H5N1, H5N6, H5N8, and H7N9 viruses. Journal of Integrative Agriculture. 2022;21(7):2086–2094. doi:10.1016/S2095-3119(22)63904-2
   Web of Science ®Google Scholar
• Shi J, Zeng X, Cui P, et al. Alarming situation of emerging H5 and H7 avian influenza and effective control strategies. Emerg Microbes Infect. 2023;12(1):2155072. doi:10.1080/22221751.2022.2155072
   PubMed Web of Science ®Google Scholar
• Subbarao K, Chen H, Swayne D, et al. Evaluation of a genetically modified reassortant H5N1 influenza A virus vaccine candidate generated by plasmid-based reverse genetics. Virology. 2003;305(1):50–54. doi:10.1006/viro.2002.1742
   PubMed Web of Science ®Google Scholar
• Tian G, Zhang S, Li Y, et al. Protective efficacy in chickens, geese and ducks of an H5N1-inactivated vaccine developed by reverse genetics. Virology. 2005;341(1):153–162. doi:10.1016/j.virol.2005.07.011
   PubMed Web of Science ®Google Scholar
• Tian G, Zeng X, Li Y, et al. Protective efficacy of the H5 inactivated vaccine against different highly pathogenic H5N1 avian influenza viruses isolated in China and Vietnam. Avian Dis. 2010;54(1 Suppl):287–289. doi:10.1637/8707-031709-ResNote.1
   PubMed Web of Science ®Google Scholar
• Cui Y, Li Y, Li M, et al. Evolution and extensive reassortment of H5 influenza viruses isolated from wild birds in China over the past decade. Emerg Microbes Infect. 2020;9(1):1793–1803. doi:10.1080/22221751.2020.1797542
   PubMed Web of Science ®Google Scholar
• OFFLU-WOAH. Influenza-A-Cleavage-Sites-Final-04-01-2022. OFFLU Network on Avian Influenza. 2022: https://www.offlu.org/wp-content/uploads/2022/01/Influenza-A-Cleavage-Sites-Final-04-01-2022.pdf.
   Google Scholar
• Hatta M, Hatta Y, Kim JH, et al. Growth of H5N1 influenza A viruses in the upper respiratory tracts of mice. PLoS Pathog. 2007;3(10):e133. doi:10.1371/journal.ppat.0030133
   PubMed Web of Science ®Google Scholar
• Jiao P, Tian G, Li Y, et al. A single-amino-acid substitution in the NS1 protein changes the pathogenicity of H5N1 avian influenza viruses in mice. J Virol. 2008;82(3):1146–1154. doi:10.1128/JVI.01698-07
   PubMed Web of Science ®Google Scholar
• Fan S, Deng G, Song J, et al. Two amino acid residues in the matrix protein M1 contribute to the virulence difference of H5N1 avian influenza viruses in mice. Virology. 2009;384(1):28–32. doi:10.1016/j.virol.2008.11.044
   PubMed Web of Science ®Google Scholar
• Feng X, Wang Z, Shi J, et al. Glycine at position 622 in PB1 contributes to the virulence of H5N1 avian influenza virus in mice. J Virol. 2016;90(4):1872–1879. doi:10.1128/JVI.02387-15
   PubMed Web of Science ®Google Scholar
• Ma S, Zhang B, Shi J, et al. Amino acid mutations A286 V and T437M in the nucleoprotein attenuate H7N9 viruses in mice. J Virol. 2020;94(2):e01530-19. doi:10.1128/JVI.01530-19
   PubMed Web of Science ®Google Scholar
• Zhang Y, Zhao C, Hou Y, et al. Biodiversity-based development and evolution: the emerging research systems in model and non-model organisms. Sci China Life Sci. 2021;64(11):1236–1280. doi:10.1007/s11427-020-1915-y
   PubMedGoogle Scholar
• Kong X, Guan L, Shi J, et al. A single-amino-acid mutation at position 225 in hemagglutinin attenuates H5N6 influenza virus in mice. Emerg Microbes Infect. 2021;10(1):2052–2061. doi:10.1080/22221751.2021.1997340
   PubMed Web of Science ®Google Scholar
• Gao Y, Zhang Y, Shinya K, et al. Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host. PLoS Pathog. 2009 Dec;5(12):e1000709. doi:10.1371/journal.ppat.1000709
   PubMed Web of Science ®Google Scholar
• de Graaf M, Fouchier RA. Role of receptor binding specificity in influenza A virus transmission and pathogenesis. Embo J. 2014;33(8):823–841. doi:10.1002/embj.201387442
   PubMed Web of Science ®Google Scholar
• Yin X, Deng G, Zeng X, et al. Genetic and biological properties of H7N9 avian influenza viruses detected after application of the H7N9 poultry vaccine in China. PLoS Pathog. 2021 Apr 27;17(4):e1009561. doi:10.1371/journal.ppat.1009561
   PubMed Web of Science ®Google Scholar
• Chen H, Bright RA, Subbarao K, et al. Polygenic virulence factors involved in pathogenesis of 1997 Hong Kong H5N1 influenza viruses in mice. Virus Res. 2007;128(1-2):159–163. doi:10.1016/j.virusres.2007.04.017
   PubMed Web of Science ®Google Scholar
• Katz JM, Lu X, Tumpey TM, et al. Molecular correlates of influenza A H5N1 virus pathogenesis in mice. J Virol. 2000;74(22):10807–10810. doi:10.1128/JVI.74.22.10807-10810.2000
   PubMed Web of Science ®Google Scholar
• Shi J, Deng G, Kong H, et al. H7N9 virulent mutants detected in chickens in China pose an increased threat to humans. Cell Res. 2017;27(12):1409–1421. doi:10.1038/cr.2017.129
   PubMed Web of Science ®Google Scholar
• Shi J, Deng G, Ma S, et al. Rapid evolution of H7N9 highly pathogenic viruses that emerged in China in 2017. Cell Host Microbe. 2018;24(4):558–568.e7. doi:10.1016/j.chom.2018.08.006
   PubMed Web of Science ®Google Scholar
• Meng F, Yang H, Qu Z, et al. A Eurasian avian-like H1N1 swine influenza reassortant virus became pathogenic and highly transmissible due to mutations in its PA gene. Proc Natl Acad Sci U S A. 2022;119(34):e2203919119. doi:10.1073/pnas.2203919119
   PubMed Web of Science ®Google Scholar
• Gu W, Shi J, Cui P, et al. Novel H5N6 reassortants bearing the clade 2.3.4.4b HA gene of H5N8 virus have been detected in poultry and caused multiple human infections in China. Emerg Microbes Infect. 2022;11(1):1174–1185. doi:10.1080/22221751.2022.2063076
   PubMed Web of Science ®Google Scholar
• Meng F, Chen Y, Song Z, et al. Continued evolution of the Eurasian avian-like H1N1 swine influenza viruses in China. Sci China Life Sci. 2023;66(2):269–282. doi:10.1007/s11427-022-2208-0
   PubMed Web of Science ®Google Scholar
• Cui P, Shi J, Yan C, et al. Analysis of avian influenza A (H3N8) viruses in poultry and their zoonotic potential, People’s Republic of China, September 2021 to May 2022. Euro Surveill. 2023;28(41):2200871. doi:10.2807/1560-7917.ES.2023.28.41.2200871
   PubMedGoogle Scholar
• Tian J, Bai X, Li M, et al. Highly pathogenic avian influenza virus (H5N1) clade 2.3.4.4b introduced by wild birds, People’s Republic of China, 2021. Emerg infect Dis. 2023;29(7):1367–1375. doi:10.3201/eid2907.221149
   PubMed Web of Science ®Google Scholar
• Karo-Karo D, Bodewes R, Restuadi R, et al. Phylodynamics of highly pathogenic avian influenza A(H5N1) virus circulating in Indonesian poultry. Viruses. 2022;14(10):2216. doi:10.3390/v14102216
   PubMed Web of Science ®Google Scholar
• WHO. Avian Influenza A (H5N1) - Cambodia. Disease Outbreak News. 2023:https://www.who.int/emergencies/disease-outbreak-news/item/2023-DON445.
   Google Scholar