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Commentary

Metabolic disruption in context: Clinical avenues for synergistic perturbations in energy homeostasis by endocrine disrupting chemicals

Article: e1080788 | Received 14 Apr 2015, Accepted 30 Jul 2015, Published online: 01 Sep 2015

References

  • American Diabetes Association. Standards of medical care in diabetes–2015. Diabetes Care 2015; 38(Suppl):S4; PMID:25537706; http://dx.doi.org/10.2337
  • Huang ES, Basu A, O'Grady M, Capretta JC. Projecting the future diabetes population size and related costs for the U.S. Diabetes care. 2009; 32:2225-9; PMID:19940225; http://dx.doi.org/10.2337/dc09-0459
  • ADA. Economic costs of diabetes in the U.S. in 2012. Diabetes Care 2013; 36:1033-46; PMID:23468086; http://dx.doi.org/10.2337/dc12-2625
  • IDF. Diabetes atlas. Brussels, Belgium: International Diabetes Federation; 2013.
  • Kuo CC, Moon K, Thayer KA, Navas-Acien A. Environmental chemicals and type 2 diabetes: an updated systematic review of the epidemiologic evidence. Curr Diab Rep 2013; 13:831-49; PMID:24114039; http://dx.doi.org/10.1007/s11892-013-0432-6
  • Thayer KA, Heindel JJ, Bucher JR, Gallo MA. Role of environmental chemicals in diabetes and obesity: a national toxicology program workshop review. Environ Health Perspect 2012; 120:779-89; PMID:22296744; http://dx.doi.org/10.1289/ehp.1104597
  • Neel BA, Sargis RM. The paradox of progress: environmental disruption of metabolism and the diabetes epidemic. Diabetes 2011; 60:1838-48; PMID:21709279; http://dx.doi.org/10.2337/db11-0153
  • Regnier SM, Kirkley AG, Ye H, El-Hashani E, Zhang X, Neel BA, Kamau W, Thomas CC, Williams AK, Hayes ET, et al. Dietary exposure to the endocrine disruptor tolylfluanid promotes global metabolic dysfunction in male mice. Endocrinology 2015; 156:896-910; PMID:25535829; http://dx.doi.org/10.1210/en.2014-1668
  • Pont A, Rubino JM, Bishop D, Peal R. Diabetes mellitus and neuropathy following Vacor ingestion in man. Arch Intern Med 1979; 139:185-7; PMID:155428; http://dx.doi.org/10.1001/archinte.1979.03630390039016
  • Fernandez-Garcia JC, Arrebola JP, Gonzalez-Romero S, Soriguer F, Olea N, Tinahones FJ. Diabetic ketoacidosis following chlorothalonil poisoning. Occup Environ Med 2014; 71(5):382; PMID:24550200
  • Sargis RM. The hijacking of cellular signaling and the diabetes epidemic: Mechanisms of environmental disruption of insulin action and glucose homeostasis. Diabetes Metab J 2014; 38:1-12; PMID:24627822; http://dx.doi.org/10.4093/dmj.2014.38.1.13
  • Naville D, Pinteur C, Vega N, Menade Y, Vigier M, Le Bourdais A, Labaronne E, Debard C, Luquain-Costaz C, Begeot M, et al. Low-dose food contaminants trigger sex-specific, hepatic metabolic changes in the progeny of obese mice. FASEB J 2013; 27:3860-70; PMID:23756648; http://dx.doi.org/10.1096/fj.13-231670
  • Ruzzin J, Petersen R, Meugnier E, Madsen L, Lock EJ, Lillefosse H, Ma T, Pesenti S, Sonne SB, Marstrand TT, et al. Persistent organic pollutant exposure leads to insulin resistance syndrome. Environ Health Perspect 2010; 118:465-71; PMID:20064776; http://dx.doi.org/10.1289/ehp.0901321
  • Sargis RM, Neel BA, Brock CO, Lin Y, Hickey AT, Carlton DA, Brady MJ. The novel endocrine disruptor tolylfluanid impairs insulin signaling in primary rodent and human adipocytes through a reduction in insulin receptor substrate-1 levels. Biochim Biophys Acta 2012; 1822:952-60; PMID:22387882; http://dx.doi.org/10.1016/j.bbadis.2012.02.015
  • Swedenborg E, Ruegg J, Makela S, Pongratz I. Endocrine disruptive chemicals: mechanisms of action and involvement in metabolic disorders. J Mol Endocrinol 2009; 43:1-10; PMID:19211731; http://dx.doi.org/10.1677/JME-08-0132
  • Barker DJ. The fetal origins of diseases of old age. Eur J Clin Nutr 1992; 46(Suppl 3):S3-9; PMID:1425543
  • Cagampang FR, Torrens C, Anthony FW, Hanson MA. Developmental exposure to bisphenol A leads to cardiometabolic dysfunction in adult mouse offspring. J Dev Orig Health Dis 2012; 3:287-92; PMID:25102149; http://dx.doi.org/10.1017/S2040174412000153
  • Chamorro-Garcia R, Sahu M, Abbey RJ, Laude J, Pham N, Blumberg B. Transgenerational inheritance of increased fat depot size, stem cell reprogramming, and hepatic steatosis elicited by prenatal exposure to the obesogen tributyltin in mice. Environ Health Perspect 2013; 121:359-66; PMID:23322813; http://dx.doi.org/10.1289/ehp.1205701
  • Wadhwa PD, Buss C, Entringer S, Swanson JM. Developmental origins of health and disease: brief history of the approach and current focus on epigenetic mechanisms. Semin Reprod Med 2009; 27:358-68; PMID:19711246; http://dx.doi.org/10.1055/s-0029-1237424
  • Florez JC, Jablonski KA, Bayley N, Pollin TI, de Bakker PI, Shuldiner AR, Knowler WC, Nathan DM, Altshuler D, Diabetes Prevention Program Research G. TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl J Med 2006; 355:241-50; PMID:16855264; http://dx.doi.org/10.1056/NEJMoa062418
  • Billings LK, Florez JC. The genetics of type 2 diabetes: what have we learned from GWAS? Ann N Y Acad Sci 2010; 1212:59-77; PMID:21091714; http://dx.doi.org/10.1111/j.1749-6632.2010.05838.x
  • Greeley SA, Naylor RN, Philipson LH, Bell GI. Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment. Curr Diab Rep 2011; 11:519-32; PMID:21993633; http://dx.doi.org/10.1007/s11892-011-0234-7
  • Rubio-Cabezas O, Hattersley AT, Njolstad PR, Mlynarski W, Ellard S, White N, Chi DV, Craig ME. The diagnosis and management of monogenic diabetes in children and adolescents. Pediatr Diabetes 2014; 15(Suppl 20):47-64; PMID:25182307; http://dx.doi.org/10.1111/pedi.12192
  • Consortium STD, Estrada K, Aukrust I, Bjorkhaug L, Burtt NP, Mercader JM, Garcia-Ortiz H, Huerta-Chagoya A, Moreno-Macias H, Walford G, et al. Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population. JAMA 2014; 311:2305-14; PMID:24915262; http://dx.doi.org/10.1001/jama.2014.6511
  • Naylor RN, John PM, Winn AN, Carmody D, Greeley SA, Philipson LH, Bell GI, Huang ES. Cost-effectiveness of MODY genetic testing: translating genomic advances into practical health applications. Diabetes care 2014; 37:202-9; PMID:24026547; http://dx.doi.org/10.2337/dc13-0410
  • Popkin BM, Gordon-Larsen P. The nutrition transition: worldwide obesity dynamics and their determinants. Int J Obes Relat Metab Disord 2004; 28(Suppl 3):S2-9; PMID:15543214; http://dx.doi.org/10.1038/sj.ijo.0802804
  • Ahima RS. Digging deeper into obesity. J Clin Invest 2011; 121:2076-9; PMID:21633174; http://dx.doi.org/10.1172/JCI58719
  • Ding S, Fan Y, Zhao N, Yang H, Ye X, He D, Jin X, Liu J, Tian C, Li H, et al. High-fat diet aggravates glucose homeostasis disorder caused by chronic exposure to bisphenol A. J Endocrinol 2014; 221:167-79; PMID:24501380; http://dx.doi.org/10.1530/JOE-13-0386
  • Wei J, Lin Y, Li Y, Ying C, Chen J, Song L, Zhou Z, Lv Z, Xia W, Chen X, et al. Perinatal exposure to bisphenol A at reference dose predisposes offspring to metabolic syndrome in adult rats on a high-fat diet. Endocrinology 2011; 152:3049-61; PMID:21586551; http://dx.doi.org/10.1210/en.2011-0045
  • Wan HT, Zhao YG, Leung PY, Wong CK. Perinatal exposure to perfluorooctane sulfonate affects glucose metabolism in adult offspring. PloS one 2014; 9:e87137; PMID:24498028; http://dx.doi.org/10.1371/journal.pone.0087137
  • Ibrahim MM, Fjaere E, Lock EJ, Naville D, Amlund H, Meugnier E, Le Magueresse Battistoni B, Froyland L, Madsen L, Jessen N, et al. Chronic consumption of farmed salmon containing persistent organic pollutants causes insulin resistance and obesity in mice. PloS One 2011; 6:e25170; PMID:21966444; http://dx.doi.org/10.1371/journal.pone.0025170
  • Gross LS, Li L, Ford ES, Liu S. Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment. Am J Clin Nutr 2004; 79:774-9; PMID:15113714
  • Lustig RH. Fructose: it's “alcohol without the buzz”. Adv Nutr 2013; 4:226-35; PMID:23493539; http://dx.doi.org/10.3945/an.112.002998
  • Koo HY, Wallig MA, Chung BH, Nara TY, Cho BH, Nakamura MT. Dietary fructose induces a wide range of genes with distinct shift in carbohydrate and lipid metabolism in fed and fasted rat liver. Biochim Biophys Acta 2008; 1782:341-8; PMID:18346472; http://dx.doi.org/10.1016/j.bbadis.2008.02.007
  • Scheer FA, Hilton MF, Mantzoros CS, Shea SA. Adverse metabolic and cardiovascular consequences of circadian misalignment. Proc Natl Acad Sci U S A 2009; 106:4453-8; PMID:19255424; http://dx.doi.org/10.1073/pnas.0808180106
  • Al-Naimi S, Hampton SM, Richard P, Tzung C, Morgan LM. Postprandial metabolic profiles following meals and snacks eaten during simulated night and day shift work. Chronobiol Int 2004; 21:937-47; PMID:15646240; http://dx.doi.org/10.1081/CBI-200037171
  • Morgan L, Hampton S, Gibbs M, Arendt J. Circadian aspects of postprandial metabolism. Chronobiol Int 2003; 20:795-808; PMID:14535354; http://dx.doi.org/10.1081/CBI-120024218
  • Arble DM, Bass J, Laposky AD, Vitaterna MH, Turek FW. Circadian timing of food intake contributes to weight gain. Obesity 2009; 17:2100-2; PMID:19730426; http://dx.doi.org/10.1038/oby.2009.264
  • Garaulet M, Gomez-Abellan P, Alburquerque-Bejar JJ, Lee YC, Ordovas JM, Scheer FA. Timing of food intake predicts weight loss effectiveness. Int J Obes 2013; 37:604-11; PMID:23357955; http://dx.doi.org/10.1038/ijo.2012.229
  • Grun F, Watanabe H, Zamanian Z, Maeda L, Arima K, Cubacha R, Gardiner DM, Kanno J, Iguchi T, Blumberg B. Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates. Mol Endocrinol 2006; 20:2141-55; PMID:16613991; http://dx.doi.org/10.1210/me.2005-0367
  • Cowherd RM, Lyle RE, McGehee RE, Jr. Molecular regulation of adipocyte differentiation. Semin Cell Dev Biol 1999; 10:3-10; PMID:10355023; http://dx.doi.org/10.1006/scdb.1998.0276
  • Regnier SM, Sargis RM. Adipocytes under assault: Environmental disruption of adipose physiology. Biochim Biophys Acta 2014; 1842:520-33; PMID:23735214; http://dx.doi.org/10.1016/j.bbadis.2013.05.028
  • Regnier SM, El-Hashani E, Kamau W, Zhang X, Massad NL, Sargis RM. Tributyltin differentially promotes development of a phenotypically distinct adipocyte. Obesity 2015; PMID:26243053; http://dx.doi.org/10.1002/oby.21174
  • Somers VK, Dyken ME, Clary MP, Abboud FM. Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest 1995; 96:1897-904; PMID:7560081; http://dx.doi.org/10.1172/JCI118235
  • Woods C, Corrigan M, Gathercole L, Taylor A, Hughes B, Gaoatswe G, Manolopoulos K, Hogan A, O'Connell J, Stewart P, et al. Tissue specific regulation of glucocorticoids in severe obesity and the response to significant weight loss following bariatric surgery (BARICORT). J Clin Endocrinol Metab 2015; 100(4):1434-44: jc20144120; PMID:25603461
  • Arnaldi G, Angeli A, Atkinson AB, Bertagna X, Cavagnini F, Chrousos GP, Fava GA, Findling JW, Gaillard RC, Grossman AB, et al. Diagnosis and complications of Cushing's syndrome: a consensus statement. J Clin Endocrinol Metab 2003; 88:5593-602; PMID:14671138; http://dx.doi.org/10.1210/jc.2003-030871
  • Newell-Price J, Trainer P, Besser M, Grossman A. The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states. Endocr Rev 1998; 19:647-72; PMID:9793762
  • Neel BA, Brady MJ, Sargis RM. The endocrine disrupting chemical tolylfluanid alters adipocyte metabolism via glucocorticoid receptor activation. Mol Endocrinol 2013; 27:394-406; PMID:23340252; http://dx.doi.org/10.1210/me.2012-1270
  • Atanasov AG, Tam S, Röcken JM, Baker ME, Odermatt A. Inhibition of 11β-hydroxysteroid dehydrogenase type 2 by dithiocarbamates. Biochem Biophys Res Commun 2003; 308:257-62; PMID:12901862; http://dx.doi.org/10.1016/S0006-291X(03)01359-7
  • Atanasov AG, Nashev LG, Tam S, Baker ME, Odermatt A. Organotins disrupt the 11β-hydroxysteroid dehydrogenase type 2–dependent local inactivation of glucocorticoids. Environ Health Perspect 2005; 113:1600-6; PMID:16263518; http://dx.doi.org/10.1289/ehp.8209
  • Odermatt A, Gumy C, Atanasov AG, Dzyakanchuk AA. Disruption of glucocorticoid action by environmental chemicals: potential mechanisms and relevance. J Steroid Biochem Mol Biol 2006; 102:222-31; PMID:17045799; http://dx.doi.org/10.1016/j.jsbmb.2006.09.010
  • Chevrier J, Dewailly E, Ayotte P, Mauriege P, Despres JP, Tremblay A. Body weight loss increases plasma and adipose tissue concentrations of potentially toxic pollutants in obese individuals. Int J Obes Relat Metab Disord 2000; 24:1272-8; PMID:11093288; http://dx.doi.org/10.1038/sj.ijo.0801380
  • Hue O, Marcotte J, Berrigan F, Simoneau M, Dore J, Marceau P, Marceau S, Tremblay A, Teasdale N. Increased plasma levels of toxic pollutants accompanying weight loss induced by hypocaloric diet or by bariatric surgery. Obes Surg 2006; 16:1145-54; PMID:16989697; http://dx.doi.org/10.1381/096089206778392356
  • Imbeault P, Chevrier J, Dewailly E, Ayotte P, Despres JP, Mauriege P, Tremblay A. Increase in plasma pollutant levels in response to weight loss is associated with the reduction of fasting insulin levels in men but not in women. Metabolism 2002; 51:482-6; PMID:11912558; http://dx.doi.org/10.1053/meta.2002.31338
  • Imbeault P, Tremblay A, Simoneau JA, Joanisse DR. Weight loss-induced rise in plasma pollutant is associated with reduced skeletal muscle oxidative capacity. Am J Physiol Endocrinol Metab 2002; 282:E574-9; PMID:11832359; http://dx.doi.org/10.1152/ajpendo.00394.2001
  • Charlier C, Desaive C, Plomteux G. Human exposure to endocrine disrupters: consequences of gastroplasty on plasma concentration of toxic pollutants. Int J Obes Relat Metab Disord 2002; 26:1465-8; PMID:12439648; http://dx.doi.org/10.1038/sj.ijo.0802144
  • Zhang W, Sargis RM, Volden PA, Carmean CM, Sun XJ, Brady MJ. PCB 126 and other dioxin-like PCBs specifically suppress hepatic PEPCK expression via the aryl hydrocarbon receptor. PloS One 2012; 7:e37103; PMID:22615911; http://dx.doi.org/10.1371/journal.pone.0037103
  • Wong TW, Wong AH, Nelson EA, Qiu H, Ku SY. Levels of PCDDs, PCDFs, and dioxin-like PCBs in human milk among Hong Kong mothers. Sci Total Environ 2013; 463–464:1230-8; PMID:22939609
  • Qu W, Suri RP, Bi X, Sheng G, Fu J. Exposure of young mothers and newborns to organochlorine pesticides (OCPs) in Guangzhou, China. Sci Total Environ 2010; 408:3133-8; PMID:20471063; http://dx.doi.org/10.1016/j.scitotenv.2010.04.023
  • Shen H, Main KM, Andersson AM, Damgaard IN, Virtanen HE, Skakkebaek NE, Toppari J, Schramm KW. Concentrations of persistent organochlorine compounds in human milk and placenta are higher in Denmark than in Finland. Hum Reprod 2008; 23:201-10; PMID:18025027; http://dx.doi.org/10.1093/humrep/dem199