Factors influencing the quality of Royal jelly and its components: a review

References

• Al–Kahtani, S. N., & Taha, E. K. A. (2020). Post grafting time significantly influences royal jelly yield and content of macro and trace elements. PloS One, 15(9), 1. https://doi.org/10.1371/journal.pone.0238751
   Web of Science ®Google Scholar
• Al–Kahtani, S., & Taha, E. K. A. (2021). Effect of harvest time on royal jelly yield and chemical composition. Journal of the Kansas Entomological Society, 93(2), 132–13. https://doi.org/10.2317/0022–8567–93.2.132
   Web of Science ®Google Scholar
• Altaye, S. Z., Meng, L., & Li, J. (2019). Molecular insights into the enhanced performance of royal jelly secretion by a stock of honeybee (Apis mellifera ligustica) selected for increasing royal jelly production. Apidologie, 50(4), 436–453. https://doi.org/10.1007/s13592–019–00656–1
   Web of Science ®Google Scholar
• Apostol, L., Belc, N., Vlăsceanu, G., Abălaru, C., Drăgancea, B., & Gaceu, L. (2019). Cocktails with bee products processed in functional products. Journal of EcoAgriTourism, 15(1), 51–56.
   Google Scholar
• Arfa, A., Ria, Y. E., & Nikeety, M. (2021). Quality parameters of royal jelly in national and international standards: specifications, differences and suggestions. Annals of the Romanian Society for Cell Biology, 25(3), 7977–7997.
   Google Scholar
• Bălan, A., Moga, M. A., Dima, L., Toma, S., Elena Neculau, A., & Anastasiu, C. V. (2020). Royal jelly–A traditional and natural remedy for postmenopausal symptoms and aging–related pathologies. Molecules (Basel, Switzerland), 25(14), 3291. https://doi.org/10.3390/molecules25143291
   PubMed Web of Science ®Google Scholar
• Bogdanov, S. (2011). Royal jelly, bee brood: composition, health, medicine: a review. Lipids, 3(8), 8–19.
   Google Scholar
• Bogdanov, S., Martin, P., & Lüllmann, C. (1997a). Harmo–nised methods of the European Honey Commission Determination of hydroxymethylfurfuralafter White. Apidologie (Extra Issue), 28, 25–27.
   Google Scholar
• Boselli, E., Caboni, M., Sabatini, A., Marcazzan, G., & Lercker, G. (2003). Determination and changes of free amino acids in royal jelly during storage. Apidologie, 34(2), 129–137. https://doi.org/10.1051/apido:2003011
   Web of Science ®Google Scholar
• Collazo, N., Carpena, M., Nuñez–Estevez, B., Otero, P., Simal–Gandara, J., & Prieto, M. A. (2021). Health promoting properties of bee royal jelly: Food of the queens. Nutrients, 13(2), 543. https://doi.org/10.3390/nu13020543
   PubMed Web of Science ®Google Scholar
• Dai, J., Shu, R., Liu, J., Xia, J., Jiang, X., & Zhao, P. (2021). Transcriptome analysis of Apis mellifera under benomyl stress to discriminate the gene expression in response to development and immune systems. Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes, 56(6), 594–605. https://doi.org/10.1080/03601234.2021.1930795
   PubMed Web of Science ®Google Scholar
• Daniele, G., & Casabianca, H. (2012). Sugar composition of French royal jelly for comparison with commercial and artificial sugar samples. Food Chemistry, 134(2), 1025–1029. https://doi.org/10.1016/j.foodchem.2012.03.008
   PubMed Web of Science ®Google Scholar
• Dobritzsch, D., Aumer, D., Fuszard, M., Erler, S., & Buttstedt, A. (2019). The rise and fall of major royal jelly proteins during a honeybee (Apis mellifera) workers’ life. Ecology and Evolution, 9(15), 8771–8782. https://doi.org/10.1002/ece3.5429
   PubMed Web of Science ®Google Scholar
• Drapeau, M. D., Albert, S., Kucharski, R., Prusko, C., & Maleszka, R. (2006). Evolution of the Yellow/Major Royal Jelly Protein family and the emergence of social behavior in honey bees. Genome Research, 16(11), 1385–1394. https://doi.org/10.1101/gr.5012006
   PubMed Web of Science ®Google Scholar
• Ellis, J. D., & Ellis, A. (2009). African Honey Bee, Africanized Honey Bee, Killer Bee, Apis mellifera scutellata Lepeletier (Insecta: Hymenoptera: Apidae): EENY 429/IN790, rev. 11/2009. EDIS, 2009(2), 1–7. https://doi.org/10.32473/edis–in790–2009
   Google Scholar
• Ferioli, F., Marcazzan, G. L., & Caboni, M. F. (2007). Determination of (E)–10–hydroxy–2–decenoic acid content in pure royal jelly: a comparison between a new CZE method and HPLC. Journal of Separation Science, 30(7), 1061–1069. https://doi.org/10.1002/jssc.200600416
   PubMed Web of Science ®Google Scholar
• Garcia-Amoedo, L. H., & Almeida-Muradian, L. B. D. (2007). Physicochemical composition of pure and adulterated royal jelly. Química Nova, 30, 257–259. https://doi.org/10.1590/S0100–40422007000200002
   Web of Science ®Google Scholar
• Gemeda, M., Legesse, G., Damto, T., & Kebaba, D. (2020). Harvesting royal jelly using splitting and grafting queen rearing methods in Ethiopia. Bee World, 97(4), 114–116. https://doi.org/10.1080/0005772X.2020.1817657
   Google Scholar
• Genç, M., & Aslan, A. (1999). Determination of trans–10–hydroxy–2–decenoic acid content in pure royal jelly and royal jelly products by column liquid chromatography. Journal of Chromatography. A, 839(1-2), 265–268. https://doi.org/10.1016/s0021–9673(99)00151–x
   PubMed Web of Science ®Google Scholar
• Guo, J., Wang, Z., Chen, Y., Cao, J., Tian, W., Ma, B., & Dong, Y. (2021). Active components and biological functions of royal jelly. Journal of Functional Foods, 82, 104514. https://doi.org/10.1016/j.jff.2021.104514
   Web of Science ®Google Scholar
• Han, B., Fang, Y., Feng, M., Hu, H., Qi, Y., Huo, X., Meng, L., Wu, B., & Li, J. (2015). Quantitative neuropeptidome analysis reveals neuropeptides are correlated with social behavior regulation of the honeybee workers. Journal of Proteome Research, 14(10), 4382–4393. https://doi.org/10.1021/acs.jproteome.5b00632
   PubMed Web of Science ®Google Scholar
• Hassoun, A., Jagtap, S., Trollman, H., Garcia-Garcia, G., Abdullah, N. A., Goksen, G., Bader, F., Ozogul, F., Barba, F. J., Cropotova, J., Munekata, P. E. S., & Lorenzo, J. M. (2022). Food processing 4.0: Current and future developments spurred by the fourth industrial revolution. Food Control. 145, 109507. https://doi.org/10.1016/j.foodcont.2022.109507
   Web of Science ®Google Scholar
• Honda, Y., Araki, Y., Hata, T., Ichihara, K., Ito, M., Tanaka, M., & Honda, S. (2015). 10–Hydroxy–2–decenoic acid, the major lipid component of royal jelly, extends the lifespan of Caenorhabditis elegans through dietary restriction and target of rapamycin signaling. Journal of Aging Research, 2015, 425261–425267. https://doi.org/10.1155/2015/425261
   PubMedGoogle Scholar
• Hossen, M. S., Nahar, T., Gan, S. H., & Khalil, M. I. (2019). Bioinformatics and therapeutic insights on proteins in royal jelly. Current Proteomics, 16(2), 84–101. https://doi.org/10.2174/1570164615666181012113130
   Web of Science ®Google Scholar
• International Organization for Standardization. (2016). ISO/DIS 12824:2016. Royal jelly – Specifications (1st ed.). Geneva, Switzerland.
   Google Scholar
• Jarvis, C. G. (2023). The effects of urbanization on disease prevalence in managed honey bee hives in Hamilton County, Tennessee (Master’s thesis). The University of Tennessee at Chattanooga, Chattanooga, Tennessee.
   Google Scholar
• Kamakura, M. (2011). Royalactin induces queen differentiation in honeybees. Nature, 473(7348), 478–483. https://doi.org/10.1038/nature10093
   PubMed Web of Science ®Google Scholar
• Kanelis, D., Tananaki, C., Liolios, V., Dimou, M., Goras, G., Rodopoulou, M. A., Karazafiris, E., & Thrasyvoulou, A. (2015). A suggestion for royal jelly specifications. Arhiv za Higijenu Rada i Toksikologiju, 66(4), 275–284. https://doi.org/10.1515/aiht–2015–66–2651
   PubMed Web of Science ®Google Scholar
• Kausar, S. H., & More, V. R. (2019). Royal Jelly. Organoleptic characteristics and physicochemical properties. Lipids, 6(2), 20–24.
   Google Scholar
• Khan, K. A., Ghramh, H. A., Ahmad, Z., El–Niweiri, M. A., & Ahamed Mohammed, M. E. (2021). Queen cells acceptance rate and royal jelly production in worker honey bees of two Apis mellifera races. PloS One, 16(4), e0248593. https://doi.org/10.1371/journal.pone.0248593
   PubMed Web of Science ®Google Scholar
• Kotronoulas, A., de Lomana, A. L. G., Karvelsson, S. T., Heijink, M., Stone, R., II, Giera, M., & Rolfsson, O. (2021). Lipid mediator profiles of burn wound healing: Acellular cod fish skin grafts promote the formation of EPA and DHA derived lipid mediators following seven days of treatment. Prostaglandins, Leukotrienes, and Essential Fatty Acids, 175, 102358. https://doi.org/10.1016/j.plefa.2021.102358
   PubMed Web of Science ®Google Scholar
• Krell, R. (1996). Value–added products from beekeeping., FAO Agricultural Services Bulletin 124. Food and Agriculture Organization of the United Nations. ISBN 92–5–103819–8;157–184.
   Google Scholar
• Kunugi, H., & Mohammed Ali, A. (2019). Royal jelly and its components promote healthy aging and longevity: From animal models to humans. International Journal of Molecular Sciences, 20(19), 4662. https://doi.org/10.3390/ijms20194662
   PubMed Web of Science ®Google Scholar
• Le Conte, Y., & Navajas, M. (2008). Climate change: impact on honey bee populations and diseases. Revue Scientifique et Technique–Office International Des Epizooties, 27(2), 499–510.
   Web of Science ®Google Scholar
• Lercker, G. (2003). La gelatina reale: composizione, autenticità ed adulterazione. In Atti del Convegno “Strategie per la valorizzazione dei prodotti dell’alveare” (pp. 67–81). Università degli Studi del Molise.
   Google Scholar
• Lercker, G., Caboni, M. F., Vecchi, M. A., Sabatini, A. G., & Nanetti, A. (1993). Caratterizzazione dei principali costituenti della gelatina reale. Apicoltura, 8(8), 27–37.
   Google Scholar
• Lercker, G., Savioli, S., Vecchi, M. A., Sabatini, A. G., Nanetti, A., & Piana, L. (1986). Carbohydrate determination of royal jelly by high resolution gas chromatography (HRGC). Food Chemistry, 19(4), 255–264. https://doi.org/10.1016/0308–8146(86)90049–X
   Web of Science ®Google Scholar
• Lercker, G., Vecchi, M. A., Piana, L., Sabatini, A. G., & Nanetti, A. (1984). Composition de la fraction lipidique de la gelée de larves d’abeilles reines et ouvrières (Apis mellifera ligustica Spinola) en fonction de l’âge des larves. Apidologie, 15(3), 303–314. https://doi.org/10.1051/apido:19840303
   Web of Science ®Google Scholar
• Li, J., Feng, M., Begna, D., Fang, Y., & Zheng, A. (2010). Proteome comparison of hypopharyngeal gland development between Italian and royal jelly producing worker honeybees (Apis mellifera L.). Journal of Proteome Research, 9(12), 6578–6594. https://doi.org/10.1021/pr100768t
   PubMed Web of Science ®Google Scholar
• Li, J., Feng, M., Zhang, Z., & Pan, Y. (2008). Identification of the proteome complement of hypopharyngeal glands from two strains of honeybees (Apis mellifera). Apidologie, 39(2), 199–214. https://doi.org/10.1051/apido:2007059
   Web of Science ®Google Scholar
• Liu, Q., Kandasamy, S., Zhai, W., Wang, H., Veeran, Y., Gao, A., & Chen, C. T. A. (2022). Temperature is a better predictor of stable carbon isotopic compositions in marine particulates than dissolved CO2 concentration. Communications Earth & Environment, 3(1), 303. https://doi.org/10.1038/s43247–022–00627–y
   Google Scholar
• Liu, J. R., Yang, Y. C., Shi, L. S., & Peng, C. C. (2008). Antioxidant properties of royal jelly associated with larval age and time of harvest. Journal of Agricultural and Food Chemistry, 56(23), 11447–11452. https://doi.org/10.1021/jf802494e
   PubMed Web of Science ®Google Scholar
• Ma, C., Ma, B., Li, J., & Fang, Y. (2022). Changes in chemical composition and antioxidant activity of royal jelly produced at different floral periods during migratory beekeeping. Food Research International (Ottawa, ON), 155, 111091. https://doi.org/10.1016/j.foodres.2022.111091
   PubMed Web of Science ®Google Scholar
• Martin, N., Hulbert, A. J., Brenner, G. C., Brown, S. H., Mitchell, T. W., & Else, P. L. (2019). Honey bee caste lipidomics in relation to life–history stage and the long life of the queen. Journal of Experimental Biology, 222(24), jeb207043. https://doi.org/10.1242/jeb.207043
   PubMed Web of Science ®Google Scholar
• Marx, Í. M., Veloso, A. C., Casal, S., Pereira, J. A., & Peres, A. M. (2021). Sensory analysis using electronic tongues. In Innovative food analysis (pp. 323–343). Academic Press.
   Google Scholar
• Mouro, G. F., & Toledo, V. A. A. (2004). Evaluation of Apis mellifera Carniolan and Africanized honeybees in royal jelly production. Brazilian Archives of Biology and Technology, 47(3), 469–476. https://doi.org/10.1590/S1516–89132004000300018
   Web of Science ®Google Scholar
• Nicolson, S. W., & Human, H. (2013). Chemical composition of the ‘low quality’pollen of sunflower (Helianthus annuus, Asteraceae). Apidologie, 44(2), 144–152. https://doi.org/10.1007/s13592–012–0166–5
   Web of Science ®Google Scholar
• Ohlinger, B. D., Schürch, R., Durzi, S., Kietzman, P. M., Silliman, M. R., & Couvillon, M. J. (2022). Honey bees (Hymenoptera: Apidae) decrease foraging but not recruitment after neonicotinoid exposure. Journal of Insect Science, 22(1), 16. https://doi.org/10.1093/jisesa/ieab095
   PubMed Web of Science ®Google Scholar
• Oršolić, N. (2013). Učinkovitost biološki aktivnih sastavnica matične mliječi: analiza I standardizacija [Royal jelly: component efficiency, analysis, and standardisation]. Arhiv za Higijenu Rada i Toksikologiju, 64(3), 445–461.
   PubMedGoogle Scholar
• Page, Jr, R. E., Rueppell, O., & Amdam, G. V. (2012). Genetics of reproduction and regulation of honeybee (Apis mellifera L.) social behavior. Annual Review of Genetics, 46(1), 97–119. https://doi.org/10.1146/annurev–genet–110711–155610
   PubMedGoogle Scholar
• Pattamayutanon, P., Peng, C. C., Sinpoo, C., & Chantawannakul, P. (2018). Effects of pollen feeding on quality of royal jelly. Journal of Economic Entomology, 111(6), 2974–2978. https://doi.org/10.1093/jee/toy251
   PubMed Web of Science ®Google Scholar
• Piana, L. (1996). Value-added products from beekeeping – Royal jelly. FAO Agricultural Services Bulletin, 124, 195–226. Food and Agriculture Organization of the United Nations: Rome
   Google Scholar
• Pourtallier, J., Davico, R., & Rognone, M. C. (1990). Les analyses dans le contrôle de pureté de la gelée royale. Abeille de France et L’Apiculteur, 753, 405–407.
   Google Scholar
• Ratajczak, M., Kaminska, D., Matuszewska, E., Hołderna–Kedzia, E., Rogacki, J., & Matysiak, J. (2021). Promising antimicrobial properties of bioactive compounds from different honeybee products. Molecules (Basel, Switzerland), 26(13), 4007. https://doi.org/10.3390/molecules26134007
   PubMed Web of Science ®Google Scholar
• Sabatini, A. G., Marcazzan, G. L., Caboni, M. F., Bogdanov, S., & Almeida-Muradian, L. B. D. (2009). Quality and standardisation of royal jelly. Journal of ApiProduct and ApiMedical Science, 1(1), 16–21. https://doi.org/10.3896/IBRA.4.01.1.04
   Google Scholar
• Saricaoglu, F. T., Cinar, A., Demircan, H., & Oral, R. A. (2019). Rheological and microstructural characterization of royal jelly at different temperatures. Journal of Food Process Engineering, 42(8), e13285. https://doi.org/10.1111/jfpe.13285
   Web of Science ®Google Scholar
• Šedivá, M., Laho, M., Kohútová, L., Mojžišová, A., Majtán, J., & Klaudiny, J. (2018). 10–HDA, A major fatty acid of royal jelly, exhibits pH dependent growth–inhibitory activity against different strains of Paenibacillus larvae. Molecules (Basel, Switzerland), 23(12), 3236. https://doi.org/10.3390/molecules23123236
   PubMed Web of Science ®Google Scholar
• Serra Bonvehi, J. (1991). Study of adulteration of royal jelly with other honeybees products and water. Investigacion Agraria. Produccion y Sanidad Animales (Spain), 6(2), 99–111.
   Google Scholar
• Shen, L. R., Wang, Y. R., Zhai, L., Zhou, W. X., Tan, L. L., Li, M. L., Liu, D. D., & Xiao, F. (2015). Determination of royal jelly freshness by ELISA with a highly specific anti–apalbumin 1, major royal jelly protein 1 antibody. Journal of Zhejiang University. Science. B, 16(2), 155–166. https://doi.org/10.1631/jzus.B1400223
   PubMed Web of Science ®Google Scholar
• Simuth, J. (2001). Some properties of the main protein of honeybee (Apis mellifera) royal jelly. Apidologie, 32, 69–80.
   Web of Science ®Google Scholar
• Taha, E. A., Al–Kahtani, S., & Taha, R. (2019). Protein content and amino acids composition of bee–pollens from major floral sources in Al–Ahsa, eastern Saudi Arabia. Saudi Journal of Biological Sciences, 26(2), 232–237. https://doi.org/10.1016/j.sjbs.2017.06.003
   PubMed Web of Science ®Google Scholar
• Takikawa, M., Kumagai, A., Hirata, H., Soga, M., Yamashita, Y., Ueda, M., Ashida, H., & Tsuda, T. (2013). 10‐Hydroxy‐2‐decenoic acid, a unique medium‐chain fatty acid, activates 5’‐AMP‐activated protein kinase in L 6 myotubes and mice. Molecular Nutrition & Food Research, 57(10), 1794–1802. https://doi.org/10.1002/mnfr.201300041
   PubMed Web of Science ®Google Scholar
• Teresa, S., Helena, R.-C., Ewa, W., & Piotr, S. (2009). Water determination in bee products using the Karl Fischer titration method. Journal of Apicultural Science, 53, 49–56.
   Web of Science ®Google Scholar
• Tourn, M. L., Lombard, A., Belliardo, F., & Buffa, M. (1980). Quantitative analysis of carbohydrates and organic acids in honeydew, honey and royal jelly by enzymic methods. Journal of Apiculture Research, 19(2), 144–146. https://doi.org/10.1080/00218839.1980.11100013
   Web of Science ®Google Scholar
• Uthaibutra, V., Kaewkod, T., Prapawilai, P., Pandith, H., & Tragoolpua, Y. (2023). Inhibition of skin pathogenic ­bacteria, antioxidant and anti–inflammatory activity of royal jelly from Northern Thailand. Molecules (Basel, Switzerland), 28(3), 996. https://doi.org/10.3390/molecules28030996
   PubMed Web of Science ®Google Scholar
• Wang, M., Gong, Q., Liu, W., Tan, S., Xiao, J., & Chen, C. (2022). Applications of capillary electrophoresis in the fields of environmental, pharmaceutical, clinical, and food analysis (2019–2021). Journal of Separation Science, 45(11), 1918–1941. https://doi.org/10.1002/jssc.202100727
   PubMed Web of Science ®Google Scholar
• Wang, W., Li, X., Li, D., Pan, F., Fang, X., Peng, W., & Tian, W. (2023). Effects of major royal jelly proteins on the immune response and gut microbiota composition in cyclophosphamide–treated mice. Nutrients, 15(4), 974. https://doi.org/10.3390/nu15040974
   PubMed Web of Science ®Google Scholar
• Yan, S., Wang, X., Sun, M., Wang, W., Wu, L., & Xue, X. (2022). Investigation of the lipidomic profile of royal jelly from different botanical origins using UHPLC–IM–Q–TOF–MS and GC–MS. LWT, 169, 113894. https://doi.org/10.1016/j.lwt.2022.113894
   Web of Science ®Google Scholar
• Youngsteadt, E., Appler, R. H., López–Uribe, M. M., Tarpy, D. R., & Frank, S. D. (2015). Urbanization increases pathogen pressure on feral and managed honey bees. PloS One, 10(11), e0142031. https://doi.org/10.1371/journal.pone.0142031
   PubMed Web of Science ®Google Scholar
• Zhou, J., Zhao, J., Yuan, H., Meng, Y., Li, Y., Wu, L., & Xue, X. (2007). Comparison of UPLC and HPLC for determination of trans–10–hydroxy–2–decenoic acid content in royal jelly by ultrasound–assisted extraction with internal standard. Chromatographia, 66(3–4), 185–190. https://doi.org/10.1365/s10337–007–0305–8
   Web of Science ®Google Scholar