Control of seizures in a clozapine-treated schizophrenia patient, using valproate: a case report

References

• Karamustafalıoğlu O, translation editor. The Maudsley prescribing guidelines in psychiatry. Taylor D, Paton C, Kapur Shitij, editors. Ankara: Ayrıntı Publishing; 2015. p. 23.
   Google Scholar
• Hamurcu HD, Caykoylu A, Peksen E, et al. A case of chronic schizophrenia who were switched from combined treatment to monotherapy and achieved a decrease in positive symptoms after lowering the clozapine dose. Klinik Psikofarmakoloji Bulteni – Bull Clin Psychopharmacol. 2016;26:324–328.
   Web of Science ®Google Scholar
• Si TM, Zhang YS, Shu L, et al. Use of clozapine for the treatment of schizophrenia: findings of the 2006 research on the China psychotropic prescription studies. Clin Psychopharmacol Neurosci. 2012;10:99–104.
   PubMedGoogle Scholar
• Cetin M, Hizli Sayar G. Risk evaluation and mitigation strategy for clozapine. Klinik Psikofarmakoloji Bulteni – Bull Clin Psychopharmacol. 2016;26:1–6.
   Web of Science ®Google Scholar
• Kose S, Akin E, Cetin M. Adverse drug reactions and causality: the Turkish version of Naranjo adverse drug reactions probability scale. Psychiatry Clin Psychopharmacol. 2017;27:205–206. doi:10.1080/ 24750573.2017.1332512.
   Web of Science ®Google Scholar
• Alkın T, translation editor. Stahl’s essential psychopharmacology. Stahl SM, editor. Istanbul: Gezegen Publishing; 2015. p. 221.
   Google Scholar
• Khokhar JY, Henricks AM, Sullivan EDK, et al. Unique effects of clozapine: a pharmacological perspective. Adv Pharmacol. 2018;82:137–162. doi:10.1016/bs.apha.2017.09.009. Epub 2018 Jan 12.
   PubMedGoogle Scholar
• Devinsky O, Pacia SV. Seizures during clozapine therapy. J Clin Psychiatry. 1994;55(Suppl B):153–156.
   Google Scholar
• Wong J, Delva N. Clozapine-induced seizures: recognition and treatment. Can J Psychiatry. 2007;52:457–463.
   PubMed Web of Science ®Google Scholar
• Varma S, Bishara D, Besag F, et al. Clozapine-related EEG changes and seizures: dose and plasma-level relationships. Ther Adv Psychopharmacol. 2011;1:47–66.
   PubMedGoogle Scholar
• Devinsky O, Honigfeld G, Patin J. Clozapine-related seizures. Neurology. 1991;41:369–371.
   PubMed Web of Science ®Google Scholar
• Ereshefsky L, Watanabe MD, Tran-Johnson TK. Clozapine: an atypical antipsychotic agent. Clin Pharm. 1989;8:691–709. [PubMed].
   PubMedGoogle Scholar
• Haller E, Binder RL. Clozapine and seizures. Am J Psychiatry. 1990;147:1069–1071. [PubMed].
   PubMed Web of Science ®Google Scholar
• Lieberman JA, Kane JM, Johns CA. Clozapine: guidelines for clinical management. J Clin Psychiatry. 1989;50:329–338. [PubMed].
   PubMed Web of Science ®Google Scholar
• Grover S, Hazari N, Chakrabarti S, et al. Association of clozapine with seizures: brief report involving 222 patients prescribed clozapine. East Asian Arch Psychiatry. 2015;25:73–78.
   PubMedGoogle Scholar
• Bolu A, Akarsu S, Pan E, et al. Low-dose clozapine-induced seizure: a case report. Clin Psychopharmacol Neurosci. 2017;15:190–193.
   Web of Science ®Google Scholar
• Wu CS, Wang SC, Yeh IJ, et al. Comparative risk of seizure with use of first- and second-generation antipsychotics in patients with schizophrenia and mood disorders. J Clin Psychiatry. 2016;77:e573–e579.
   PubMed Web of Science ®Google Scholar
• Squires RF, Saederup E. A review of evidence for GABAergic predominance/glutamatergic deficit as a common etiological factor in both schizophrenia and affective psychoses: more support for a continuum hypothesis of “functional” psychosis. Neurochem Res. 1991;16:1099–1111.
   PubMed Web of Science ®Google Scholar
• Mansour A, Meador-Woodruff JH, Burke S, et al. Differential distribution of D2 and D4 dopamine receptor mRNAs in rat brain: an in situ hybridization study. Soc Neurosci Abstr. 1991;17:599.
   Google Scholar
• Arvanov VL, Wang RY. Clozapine, but not haloperidol, prevents the functional hyperactivity of N-methyl-D-aspartate receptors in rat cortical neurons induced by subchronic administration of phencyclidine. J Pharmacol Exp Ther. 1999;289:1000–1006.
   Web of Science ®Google Scholar
• Liu Y, Hu C, Tang Y, et al. Clozapine inhibits strychnine sensitive glycine receptors in rat hippocampal neurons. Brain Res. 2009;1278:27–33.
   Web of Science ®Google Scholar
• Singhal SK, Zhang L, Morales M, et al. Antipsychotic clozapine inhibits the function of alpha7-nicotinic acetylcholine receptors. Neuropharmacology. 2007;52:387–394.
   Web of Science ®Google Scholar
• Squires RF, Saederup E. Clozapine and several other antipsychotic/antidepressant drugs preferentially block the same “core” fraction of GABA(A) receptors. Neurochem Res. 1998;23:1283–1290.
   Web of Science ®Google Scholar
• Steward LJ, Kennedy MD, Morris BJ, et al. The atypical antipsychotic drug clozapine enhances chronic PCP-induced regulation of prefrontal cortex5-HT2A receptors. Neuropharmacology. 2004;47:527–537.
   Web of Science ®Google Scholar
• Caetano D. Use of anticonvulsants as prophylaxis for seizures in patients on clozapine. Australas Psychiatry. 2014;22:78–83.
   PubMed Web of Science ®Google Scholar
• Williams AM, Park SH. Seizure associated with clozapine: incidence, etiology, and management. CNS Drugs. 2015;29:101–111.
   PubMed Web of Science ®Google Scholar
• Pisani LR, Nikanorova M, Landmark CJ, et al. Specific patient features affect antiepileptic drug therapy decisions: focus on gender, age, and psychiatric comorbidities. Curr Pharm Des. 2017;23:5639–5648.
   PubMed Web of Science ®Google Scholar
• Kashiwagi H, Ikezawa S, Sumiyoshi T, et al. A case of schizophrenia comorbid for tetralogy of Fallot treated with clozapine: further considerations on a role for 22q.11.2 in the proneness for seizures. Neuropsychiatr Dis Treat. 2017;13:2271–2273.
   Web of Science ®Google Scholar
• Kikuchi YS, Sato W, Ataka K, et al. Clozapine induced seizures, electroencephalography abnormalities, and clinical responses in Japanese patients with schizophrenia. Neuropsychiatr Dis Treat. 2014;10:1973–1978.
   PubMed Web of Science ®Google Scholar
• Dhar R, Singh T, Chavan BS. Clozapine-induced drop-attack and myoclonus. German J Psychiatry. 2008;11:29–31.
   Google Scholar
• Berman I, Zalma A, DuRand CJ, et al. Clozapine-induced myoclonic jerks and drop attacks. J Clin Psychiatry. 1992;53:329–330.
   PubMed Web of Science ®Google Scholar