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Key Paper Evaluation

The hedgehog pathway inhibitor GDC-0449 shows potential in skin and other cancers

Evaluation of: Von Hoff DD, LoRusso PM, Rudin CM, et al. Inhibition of the hedgehog pathway in advanced basal-cell carcinoma. N Engl J Med 2009;361:1164-62, and Rudin CM, Hann CL, Laterra J, et al. Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449. N Engl J Med 2009;361:1173-8

, PhD DSc
Pages 451-454 | Published online: 17 Jan 2010

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