120
Views
15
CrossRef citations to date
0
Altmetric
Miscellaneous

Do peroxisome proliferation receptor-γ antagonists have clinical potential as combined antiobesity and antidiabetic drugs?

Pages 713-716 | Published online: 02 Mar 2005

Bibliography

  • RIEUSSET J, TOURI F, MICHALIK L et al.: A new selective perwdsome proliferator-activated receptor y antagonist with antiobesity and antidiabetic activity. Mai Endocrinol (2002) 16:2628–2644.
  • MORI Y, MURAKAWA Y, OKADA K et al.: Effect of troglitazone on body fat distribution in Type 2 diabetic patients. Diabetes Care (1999) 22:908–912.
  • HIROSE H, KAWAI T, YAMAMOTO Y et al.: Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with Type 2 diabetes. Metabolism (2002) 51:314–317.
  • KERSEN S, DESVERGNE B, WAHLI W: Roles of PPARs in health and disease. Nature (2000) 405:421–424.
  • DEEB SS, FAJA L, NEMOTO M et al.: A Pro12Ala substitution in PPARy2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat. Genet. 20:284–287.
  • KUBOTA N, TERAUCHI Y, MIKI H et al.: PPARy mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mai Cell (1999) 4:597–609.
  • OBERFIELD JL, COLLINS JL, HOLMES CP et al: A peroxisome proliferator-activated receptor y ligand inhibits adipocyte differentiation. Proc. Nati Acad. Sci. USA (1999) 96:6102–6106.
  • WRIGHT MH, CLISH CB, MIKAMI T et al.: A synthetic antagonist for the perwdsome proliferator-activated receptor gamma inhibits adipocyte differentiation. J. Biol. Chem. (2000) 275:1873–1877.
  • MUKHERJEE R, HOENER PA, JOW L et al.: A selective peroxisome proliferator-activated receptor y (PPARy) modulator bocks adipocyte differentiation but stimulates glucose uptake in 3T3-L1 adipocytes. Mal Endocrinol (2000) 14:1425–1433.
  • CAMP HS, CHAUDRY A, LEFF T: A novel potent antagonist of perwdsome proliferator-activated receptor gamma blocks adipocyte differentiation but does not revert the phenotype of terminally differentiated adipocytes. Endocrinology (2001) 142:3207–3213.
  • YAMAUCHI T, WAKI H, KAMON J et al.: Inhibition of RXR and PPARy ameliorates diet-induced obesity and Type 2 diabetes. Clin. Invest. 108:1001-1013.
  • FROHBECK G, GOMEZ-AMBROSI, MURUZÁBAL FJ, BURRELL MA: The adipocyte: a model for integration of endocrine and metabolic signaling in energy metabolism regulation. Am. I Physiol Endocrinol Metab. 280:E827–E847.
  • ADAMSON DJ, FREW D, TATOUD R, WOLF CR, PALMER CN: Diclofenac antagonizes perwdsome proliferator-activated receptor-7 signaling. Mal Pharmacol (2002) 61:7–12.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.