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- ••Clinical study that provides proof that thesuppression of hyperinsulinaemia in obese adults with insulin hypersecretion by use of SMS analogue treatment is effective and favours weight loss.
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- ••Landmark paper which describes VEGF asprim= movens in DR at an advanced stage.
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- ••First controlled trial which showed that theuse of the SMS analogue octreotide was effective in reducing progression of DR at clinical stages just prior to laser coagulation.
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- ••First controlled trial showing thatoctreotide is effective in advanced stages of DR, i.e., after panretinal laser coagulation to stop progression.
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- •Clinical trial that details markers of endothelial dysfunction under SMS analogue therapy.
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