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Drug Evaluation

Atrasentan: targeting the endothelin axis in prostate cancer

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Pages 1631-1640 | Published online: 24 Feb 2005

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  • ZHU T, ANDRE A, FACEY I et al.: Effectof ketoconazole (KET) on the pharmacokinetics (PK) of atrasentan (ABT-627, ATN). Proceedings of the 40th American Socieg, of Clinical Oncology annual meeting. New Orleans, LA, USA (2004) Abstract 4727.
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  • ••The first evaluation of atrasentanadministration in humans.
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  • ••The first report of a clinical trial assessingthe efficacy of atrasentan in patients with prostate cancer.
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  • •An elegant paper showing the translational research results of the Phase II trial of atrasentan in prostate cancer patients.
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