Bioliography
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- PEETERS A, BARENDREGT JJ, WILLEKENS F et al.: Obesity in adulthood and its consequences for life expectancy: a life-table analysis. Ann. Intern. Med. (2003) 138:24–42.
- HARDIE DG: The AMP-activated protein kinase cascade: the key sensor of cellular energy status. Endocrinology (2003) 144:5179–5183.
- ANDERSSON U, FILIPSSON K, ABBOTT CR et al: AMP-activated protein kinase plays a role in the control of food intake. J. Biol. Chem. (2004) 279:12005–12008.
- MINOKOSHI Y, ALQUIER T, FURUKAWA N et al: AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature (2004) 428:569–574.
- MUST N, HIRSHMAN MF, NYGREN J et al.: Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with Type 2 diabetes. Diabetes (2002) 51:2074–2081.
- JACOB S, STREEPER RS, FOGT DL et al: The antioxidant a-lipoic acid enhances insulin-stimulated metabolism in insulin-resistant rat skeletal muscle. Diabetes (1996) 45:1024–1029.
- EASON RC, ARCHER HE, AKHTAR S, BAILEY CJ: Lipoic acid increases glucose uptake by skeletal muscles of obese diabetic ob/ob mice. Diabetes Obes. Metab. (2002) 4:29–35.
- BITAR MS, WAHID S, PILCHER SM, AL-SALEH E, AL-MULLA F: a-Lipoic acid mitigates insulin resistance in Goto-Kakizaki rats. Harm Metab. Res. (2004) 36:542–549.
- ZIEGLER D, HANEFELD M, RUHNAU KJ et al.: Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant a-lipoic acid. A 3-week multicentre randomized controlled trial (ALADIN Study). Diabetologia (1995) 38:1425–1433.
- BERNKOP-SCHNURCH A, REICH-ROHRWIG E, MARSCHULTZ M, SCHUHBAUER M, KRATZEL M: Development of a sustained release dosage form for a-lipoic acid. II. Evaluation in human volunteers. Drug Dev. had. Phann. (2004) 30:35-42. Affiliation Sheila A Doggrell PhD, DSc Doggrell Biomedical Communications, 47 Caronia Crescent, Lynfield, Auckland, New Zealand E-mail: [email protected]