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Original Research

An investigation of the effect of sorafenib on tumour growth and recurrence after liver cancer resection in nude mice independent of phosphorylated extracellular signal-regulated kinase levels

, , , , , , & , MD PHD show all
Pages 1039-1045 | Published online: 14 Jun 2011

Bibliography

  • El-Serag HB. Epidemiology of hepatocellular carcinoma in USA. Hepatol Res 2007;37:S88-94
  • Kudo M. Hepatocellular carcinoma 2009 and beyond: from the surveillance to molecular targeted therapy. Oncology 2008;20:S1-12
  • Tang ZY, Yu YQ, Zhou XD, Progress and prospects in hepatocellular carcinoma surgery. Ann Chir 1998;52:558-63
  • Addeo R, Caraglia M, Del Prete S. Highlights of regional meeting of Italian Southern Oncological Group (GOIM): focus on hepatocellular carcinoma: biological and clinical background, therapeutic guide-lines and perspectives. 7 November 2008, Naples, Italy. Expert Opin Investig Drugs 2009;18(3):373-8
  • Ercolani G, Grazi GL, Ravaioli M, Liver resection for hepatocellular carcinoma on cirrhosis. Ann Surg 2003;237:536-43
  • Regimbeau JM, Abdalla EK, Vauthey JN, Risk factors for early death due to recurrence after liver resection for hepatocellular carcinoma: results of a multicenter study. J Surg Oncol 2004;85:36-41
  • Kohno H, Nagasue H, Hayashi T, Postoperative adjuvant chemotherapy after radical hepatic resection for hepatocellular carcinoma (HCC). Hepatogastroenterology 1996;43:1405-9
  • Lai EC, Lo CM, Fan ST, Postoperative adjuvant chemotherapy after curative resection of hepatocellular carcinoma. Arch Surg 1998;133:183-8
  • Lin SM, Lin CJ, Hsu CW. Prospective randomized controlled study of interferon-alpha in preventing hepatocellular carcinoma recurrence after medical ablation therapy for primary tumors. Cancer 2003;100:376-82
  • Mazzaferro V, Romito R, Schiavo M, Prevention of hepatocellular carcinoma recurrence with alpha-interferon after liver resection in HCV cirrhosis. Hepatology 2006;44:1543-54
  • Lau WY, Leung TW, Ho SK, Adjuvant intra-arterial iodine-131-labelled lipiodol for respectable hepatocellular carcinoma: a prospective randomised trial. Lancet 1999;353:797-801
  • Yamamoto M, Arii S, Sughara K, Adjuvant oral chemotherapy after curative resection of hepatocellular carcinoma. Br J Surg 1996;83:336-40
  • Ono T, Nagasue N, Kohno H, Adjuvant chemotherapy with epirubicin and carmfur after radical resection of hepatocellular carcinoma: a prospective randomized study. Semin Oncol 1997;24:S6-18
  • Takayama T, Sekine T, Makuuchi M, Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomized trial. Lancet 2000;356:802-7
  • Llovet JM, Bruix J. Novel advancements in the management of hepatocellular carcinoma in 2008. J Hepatol 2008;48:S20-37
  • Worns MA, Galle PR. Novel inhibitors in development for hepatocellular carcinoma. Expert Opin Investig Drugs 2010;19:615-29
  • Llovet JM, Ricci S, Mazzaferro V, Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008;359:378-90
  • Zhang Z, Zhou X, Shen H, Phosphorylated ERK is a potential predictor of sensitivity to sorafenib when treating hepatocellular carcinoma: evidence from an in vitro study. BMC Med 2009;7:41
  • Chang YS, Adnane J, Trail PA, Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models. Cancer Chemother Pharmacol 2007;59:561-74
  • Huynh H, Nguyen TT, Chow KH, Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: its role in tumor progression and apoptosis. BMC Gastroenterol 2003;3:19
  • Roberts PJ, Der CJ. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 2007;26:3291-310
  • Wilhelm SM, Carter C, Tang L, BAY 43-9006 exhibits broad spectrum oral anti-tumor activity and targets the Raf/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 2004;64:7099-109
  • Wilhelm SM, Adnane L, Newell P, Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling. Mol Cancer Ther 2008;7:3129-40
  • Zhang W, Konopleva M, Ruvolo VR, Sorafenib induces apoptosis of AML cells via Bimmediated activation of the intrinsic apoptotic pathway. Leukemia 2008;22:808-18
  • Abou-Alfa GK, Schwartz L, Ricci S, Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. J Clin Oncol 2006;24:4293-300
  • Feng YX, Wang T, Deng YZ, Sorafenib suppresses postsurgical recurrence and metastasis of hepatocellular carcinoma in an orthotopic mouse model. Hepatology 2011;53:483-92
  • Kim R, El-Gazzaz G, Tan A, Safety and feasibility of using sorafenib in recurrent hepatocellular carcinoma after orthotopic liver transplantation. Oncology 2010;79:62-6

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