Advanced search
Publication Cover
Expert Opinion on Investigational Drugs Volume 5, 1996 - Issue 1
Submit an article Journal homepage
9
Views
0
CrossRef citations to date
0
Altmetric
Original Article

Monthly Update: Pulmonary-Allergy, Dermatological, Gastrointestinal & Arthritis: Inhibitors of inducible cyclo-oxygenase (COX-2): Anti-inflammatory drugs with improved tolerability?

Michael J Parnham Parnham Advisory Services, Von Guericke Allee 4, D-53125, Bonn, Germany
Pages 111-114 | Published online: 03 Mar 2008

References

  • VANE JR, BOTTING RM: The mode of action of anti-in- flammatory drugs. Postgrad. Med. J. (1990) 66\(Suppl. 4): S2–S17.
  • LICH1ENSTEIN DR, SYNGAL S, WOLFE MM: b>Nonsteroidal antiinflammatory drugs and the gastrointestinal tract. The double-edged sword. Artbr. Rheum, (1995) 38:5–8.
  • WALKER L, FROLICH JC: Renal prostaglandins and leuk-otrienes. Rev. Physiol. Biochem. Pharmacol. (1987) 107:1- 72.
  • XIE W, ROBERTSON DL, SIMMONS DL: Mitogen-inducibleprostaglandin G/H synthase: anew target for nonsteroi-dal antiinflammatory drugs. Drug Dev . Res. (1992) 25:249–265.
  • DAY RO: Variability in response to NSAIDs: what pro-gress? In: Variability in Response to Anti-Rheumatic Drugs. Brooks PM, Day RO, Graham GG, Williams KM (Eds.), Agents and Actions Suppl. 44. Birkhauser Verlag, Basel (1993):3–6.
  • IIERBEI IL LG: b>Membrane pathways for drug/ion chan-nel interactions: molecular basis for pharmacoldnetic properties. Drug Dev. Res. (1994) 33:214-224.
  • NEWMAN NM, LING RSM: Acetabular bone destructionrelated to non-steroidal anti-inflammatory drugs. Lan-cet(1985) 2:11–14.
  • FRIES JF, SPITZ PW, WILLIAMS CA, BLOCH DA, SINGII G,HUI3ERT HB A toxicity index for comparison of side-ef-fects among different drugs. Arthr. Rheum. (1990) 33:121-130.
  • HAYLLAR J, BJAILNASON I: NSAIDs, COX-2 inhibitors, andthe gut. Lancet (1995) 346:521-522.
  • VANE JR, MITCHELL JA, APPLETON I, TOMLINSON A, 131S1-10P-BAILEY D, CROXTALL J, WILLOUGHBY DA: In-ducible isoforms of cyclo-oxygenase and nitric oxide synthase in inflammation. Proc. Natl. Acad. Set. USA (1994) 91:2046–2050.
  • VANE JR, BOTTING RM: New insights into the mode ofaction of anti-inflammatory drugs. Inflamm. Res. (1995) 44:1–10.
  • LC X, XIE W, REED D, BRADSHAW WS, SIMMONS DL: Nonsteroidal anti-inflammatory drugs cause apoptos is and induce cyclo-oxygenases in chicken embryo fi-broblasts. Proc. Natl. Acad. Sci. USA (1995) 82. In press. Michael J Parnham, Pamham Advisory Services, Von Guericke Alice 4, D-53125 Bonn, Germany.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.