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Review

Recent developments in pradimicin-benanomicin and triazole antibiotics

&
Pages 129-145 | Published online: 03 Mar 2005

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  • OAKLEY KL, MOORE CB, DENNING, DW: In vitro activity of SCH-56592 against Aspergillus spp. and comparison with itraconazole and amphotericin B. 36th Interscience Conference on Antimicrobial Agents and Chemotherapy. New Orleans, USA (1996):F90.
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  • OAKLEY KL, MORRISSEY G, DENNING DW: Efficacy of Sch-56592 in 2 immunocompromised murine models of invasive aspergillosis. 36th Interscience Conference on Antimicrobial Agents and Chemotherapy New Orleans, USA (1996):F97.
  • PATTERSON TF, KIRKPATRICK VVR, MCATEE RK, LOEBEN-BERG D: Efficacy of SCH 56592 in a rabbit model of invasive aspergillosis. 36th Interscience Conference on Antimicrobial Agents and Chemotherapy New Orleans, USA (1996):F98.
  • GRAYBILL J, NAJVAR L, BOCANEGRA R et al: Treatment of murine pulmonary aspergillosis with Sch 56592. 36th Interscience Conference on Antimicrobial Agents and Che-motherapy New Orleans, USA (1996):F99.
  • LUTZ JE, CLEMONS KV, STEVENS DA: Efficacy of SCH 56592 in a murine model of systemic coccidiodomy-cosis. 36th Interscience Conference on Antimicrobial Agents and Chemotherapy New Orleans, USA (1996). Abstract F100.
  • URBINA JA, PAYARES G, SANOJA C et al: In vitro and in vivo antiproliferative effects of SCH 56592 against Try-panosoma cruzi the causative agent of Chagas disease. 36th Interscience Conference on Antimicrobial Agents and Chemotherapy New Orleans, USA (1996). Abstract F101.
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  • HITCHCOCK CA, PYE GW, OLIVER GP, TROKE PF: UK-109,496, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: antifungal activity and selectivity in vitro. 35th Interscience Conference on Antimicrobi a I AgentsandChemotherapy. San Francisco, USA (1995):F72.
  • SANATI H, BELANGER PH, FRATTI RA, GHANNOUM MA: Effect of voriconazole (UK-109,496) on the sterol bio-synthesis of Candida al bicans and Candida krusei. 36th Interscience Conference on Antimicrobial Agents and Che-motherapy New Orleans, USA (1996):C65.
  • BARCHIESI F, RESTREPO M, MCGOUGH DA, RINALDI MG: In vitro activity of a new antifungal triazole: UK-109,496. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy.San Francisco, USA (1995):F71.
  • OAKLEY KL, MOORE CB, DENNING DW: In vitro activity of voriconazole against Aspergillus spp. and compari-son with amphotericin B and itraconazole. 36th Inter-science Conference on Antimicrobial Agents and Chemotherapy. New Orleans, USA (1996). Abstract F81.
  • ESPINEL-INGROFF A, FLYNN T: Antifungal activity of the new triazole voriconazole against established, new and emerging yeast pathogens: a comparative study. 36th Interscience Conference on Antimicrobial Agents and Che-motherapy. New Orleans, USA (1996):F83.
  • ESPINEL-INGROFF A: Evaluation of the in vitro activity of the new triazole voriconazole against opportunistic filamentous fungi. 36th Interscience Conference on Antimi-crobial Agents and Chemotherapy New Orleans, USA (1996):F84.
  • SUTTON DA, FOTHERGILL AW, BARCHIESI FJ, RINALDI MG: In vitro activity of voriconazole against dimorphic fungi. 36th Interscience Conference on Antimicrobial Agents and Chemotherapy. New Orleans, USA (1996):F85.
  • MCGINNIS MR, PASARELL L, COOPER CR JR: In vitro susceptibility of clinical mould isolates to UK-109,496, amphotericin B, fluconazole, and itraconazole. 35th Interscience Conference on Antimicrobial Agents and Che-motherapy. San Francisco, USA (1995):E76.
  • JEZEQUEL SG, CLARK M, COLE S et al.: UK-109,496, a novel, wide-spectrum triazole derivative for the treat-ment of fungal infections: pre-clinical pharmacokinet-ics. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, USA (1995):F76.
  • JEZEQUEL SG, CLARK M, EVANS K et al: UK-109,496, a novel, wide-spectrum triazole derivative for the treat-ment of fungal infections: disposition in animals. 35th Interscience Conference on Antimicrobial Agents and Che-motherapy. San Francisco, USA (1995):F77.
  • TROKE PF, BRAMMER KW, HITCHCOCK CA et al.: UK-109,496, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: activity in systemic models and early clinical efficacy in oropharyngeal candidiasis. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy San Francisco, USA (1995):F73.
  • HITCHCOCK CA, ANDREW RJ, lEWIS BGH, TROKE PF: UK-109, 496, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: antifungal activ-ity in experimental infection with Cryptococcus. 35th Interscience Conference on Antimicrobial Agents and Che-motherapy. San Francisco, USA (1995):F75.
  • HITCHCOCK CA, ANDREW RJ, 1EWIS BGH, TROKE PF: UK-109, 496, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: antifungal activ-ity in experimental infectons with Aspergillus. 35th Interscience Conference on Antimicrobial Agents and Che-motherapy San Francisco, USA (1995):F74.
  • MARTIN MV, YEATS J, HITCHCOCK CA: Voriconazole (UK-109,496): a novel, wide-spectrum triazole deriva-tive for the treatment of fungal infections: antifungal activity in experimental Asp ergillus endocarditis. 36th Interscience Conference on Antimicrobial Agents and Che-motherapy New Orleans, USA (1996):F86.
  • PATTERSON BE, COATES PE: UK-109,496, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: pharmacokinetics in man. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, USA (1995):F78.
  • JEQEQUEL SG, GIBSON A, HYLAND R et al.: UK-109,496, a novel, wide-spectrum triazole derivative for the treat-ment of fungal infections: disposition in man. 35th Interscience Conference on Antimicrobial Agents and Che-motherapy San Francisco, USA (1995):F79.
  • DENNING DW, DEL FAVERO A, GLUCKMAN E et al: UK-109,496, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: clinical efficacy in acute invasive aspergillosis. 35th Interscience Confer-ence on Antimicrobial Agents and Chemotherapy San Fran-cisco, USA (1995):F80.
  • DUPONT B, DENNING D, LODE H et al: UK-109,496, a novel, wide-spectrum triazole derivative for the treat-ment of fungal infections: clinical efficacy in chronic invasive aspergillosis. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy.San Francisco, USA (1995):F81.
  • NAITO T, KAKU Y, TSURUOKA A eta].: ER-30346, a novel antifungal triazole: 1. Synthesis and structure-activity relationships of new thiazole-containing triazole anti-fungals. 35th Interscience Conference on Antimicrobial Agents and ChemotherapySan Francisco, USA (1995):F91.
  • HATA K, KIMURA J, MIKI H et al: In vitro and in vivo antifungal activities of ER30346, a novel oral triazolewith a broad antifungal spectrum. Antimicrob. Agents Chemother. (1996) 40:2237–2242.
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