Clinical trials of chemotherapy for falciparum malaria

Bibliography

• SNOW RW, OMUMBO JA, LOWE B et al.: Relation be- tween severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa. Lancet (1997) 349 (9066):1650–1654.
   PubMed Web of Science ®Google Scholar
• Essential Malariology (Third edition). Gilles HM, Warren DA (Eds.), Edward Arnold, London, UK (1993).
   Google Scholar
• PHILLIPS M, PHILLIPSHOWARD PA: Economic-implications of resistance to antimalari aldrugs. Phar-macoeconomics (1996) 10 (3):225–238.
   PubMed Web of Science ®Google Scholar
• WATKINS WM, MBERU EK, WINSTANLEY PA, PLOWE C: The efficacy of antifolate combinations in Africa: a predictive model based on pharmacodynamic and ph armacokin etic analyses. Parasitology Today. (In Press.)
   Google Scholar
• OLLIARO P, NEVILL C, LEBRAS J eta].: Systematic review of amodiaquine treatment in uncomplicated malaria. Lancet (1996) 348 (9036):1196–1201.
   Google Scholar
• WHITE NJ: Artemisinin: proceedings of a meeting con-vened by the Wellcome Trust on 25–27 April 1993. Trans. Roy. Soc. Trop. Med. Hyg. (1994) 88 (Suppl.):1–65.
   Google Scholar
• WINSTANLEY PA, BRECKENRIDGE AM: Tropical medi-cine: therapeutics and drug development. Lancet (1997) 349 (Suppl. III):3–4.
   Google Scholar
• MARSH K, FORSTER D, WARUIRU C et al.: Indicators oflife-threatening malaria in African children. New. Engl. J. Med. (1995) 332:1399–404.
   PubMed Web of Science ®Google Scholar
• MURPHY S, ENGLISH M, WARUIRU C eta].: An open ran-domised trial of artemether versus quinine in the treatment of cerebral malaria in African children. Trans. Roy. Soc. Trop. Med. Hyg. (1996) 90:298–301.
   Google Scholar
• VAN HENSBROEK MB, ONYIORAH E, JAFFAR S et al.: A trial of artemether or quinine in children with cere-bral malaria. New. Engl. J Med. (1996) 335 :69–75.
   PubMed Web of Science ®Google Scholar
• HIEN T, DAY N, PHU N etal.: Acontrolled trial of arteme-ther or quinine in Vietnamese adults with severe falciparum-malaria. New. Engl. J. Med. (1996) 335:76–83.
   Google Scholar
• MURPHY SA, MBERU E, MUHIA D et al.:The disposition of im. artemether in children with cerebral malaria: a preliminary study. Trans. Roy. Soc. Trop. Med. Hyg. (1997) 91:331–334.
   PubMed Web of Science ®Google Scholar
• WHITE NJ, KRISHNA S: Treatment of malaria -some con-siderations and limitations of the current methods of assessment. Trans. Roy. Soc. Trop. Med. Hyg. (1989) 83 (6):767–777.
   PubMed Web of Science ®Google Scholar
• LOOAREESUWAN S, KYLE DE, VIRAVAN C eta].: Clinical-study of pyronaridine for the treatment of acute un-complicated falciparum-malaria in thailand. Am. J. Trop. Med. Hyg. (1996) 54 (2):205–209.
   Google Scholar
• RINGWALD P, BICKII J, BASCO L: Randomized trial of pyronaridine versus chloroquine for acute uncompli-cated falciparum-malaria in africa. Lancet (1996) 347 (8993):24–28.
   PubMed Web of Science ®Google Scholar
• WINSTANLEY PA, MBERU EK, SZWANDT ISF, BRECKEN-RIDGE AM, WATKINS WM: The in vitro activity of novel an tifolate drug combinations against Plasmodium fal-ciparum and human granulocyte colony-forming-units. Antimicr. Agents Chemother. (1995) 39:948–952.
   PubMed Web of Science ®Google Scholar
• PLOWE, CV, DJIMDE A, WELLEMS TE, KOURIBA B,DOUMBO OK: Community pyrimethamine use and prevalence of resistant Plasmodium falciparum geno-types in Mali: a model for deterring resistance. Am. J Trop. Med. Hyg. (1996) 55:467–471.
   PubMed Web of Science ®Google Scholar
• WATKINS WM, BRANDLING-BENNETT AD, NEVILL CG etChlorproguanil/dapsone for the treatment of non-severe Plasmodium falciparummalaria in Kenya: a pi-lot study. Trans. Roy. Soc. Trop. Med. Hyg. (1988) 82:398.
   PubMed Web of Science ®Google Scholar
• WINSTANLEY PA,WATKINS WM, MUHIA D et al.: Chlorprog-uanil-dapsone for uncomplicated falcipa-rum malaria in young children: pharmacokinetics and therapeutic range. Trans. Roy. Soc. Trop. Med. Hyg. (1997) 91:322–327.
   PubMed Web of Science ®Google Scholar
• AMUKOYE E, WINSTANLEY PA, WATKINS WM et al.: Chlorprog-uanil-dapsone: an effective treatment for uncomplicated falcip arum malaria. Antimicr. Agents Chemother. (1997) 41:2261–2264.
   PubMed Web of Science ®Google Scholar
• COMLEY JC, STERLING AM: Effect of atovaquone and atovaquone drug combinations on prophylaxis of Pneumocystis carinii pneumonia in SCID mice. Anti-microb. Ags. Chemother. (1995) 39(4):806–811.
   PubMed Web of Science ®Google Scholar
• GAY F, BUSTOS D, TRAORE B eta].: In vitroresp on se of Plasmodium falciparum to atovaquone and correla-tion with other antimalarials: comparison between African and Asian strains. Arm J Trop. Med. Hyg. (1997) 56 (3):315–317.
   Google Scholar
• LOOAREESUWAN S, VIRAVAN C, WEBSTER HK et al.: Clinical studies of atovaquone, alone or in combina-tion with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand. Arm J Trop. Med. Hyg. (1996) 54(1):62–66.
   PubMed Web of Science ®Google Scholar
• CANFIELD CJ, PUDNEY M, GUTTERIDGE WE: Interac-tions of atovaquone with other antimalarial. Exp. Para-sitol (1995) 80(3):373–381.
   PubMed Web of Science ®Google Scholar
• YEO AE, SEYMOUR KK, RIECKMANN KH, CHRISTOPHER-SON RI: Effects of dual combinations of antifolates with atovaquone or dapsone on nucleotide levels in Plas-modium falciparum. Biochem. Pharmacol. (1997) 53 (7):943–950.
   PubMed Web of Science ®Google Scholar
• EDSTEIN MD, YEO AE, KYLE DE eta].: Proguanil poly-morphism does not affect the antimalarial activity of prog-uanil combined with atovaquone in vitro. Trans. Roy. Soc. Trop. Med. Hyg. (1996) 90(4):418–421.
   Google Scholar
• DE ALENCAR FE, CERUTTI C JR, DURLACHER RR eta": Ato-vaquone and prog-uanil for the treatment of malaria in Brazil. J. Infect. Dis. (1997) 175 (6) :1544–1547.
   PubMed Web of Science ®Google Scholar
• RADLOFF PD, PHILIPPS J, NKEYI M, HUTCHINSON D, KREMSNER PG: Atovaquone and proguanil for Plasmo-dium falciparum malaria. Lancet (1996) 347 (9014):1511–1514.
   PubMed Web of Science ®Google Scholar
• Meeting the challenge: CGP 56697, a novel antimalar-ial combination. Satellite Symposium: 5th Western Pacific Congress of Chemotherapy and Infectious Diseases. Singa-pore, December (1996).
   Google Scholar
• VAN VUGT M, LOOAREESUWAN S, WILAIRATANA P eta].: Artemether-benflumetol: a new treatment of mul-tidrug resistant Plasmodium falciparum malaria in Thailand. Joint International Tropical Medicine Meeting. Bangkok, Thailand, August (1997). Abstract 45.
   Google Scholar
• LOOAREESUWAN S, WILAIRATANA P, MOLUNTO W eta].: A comparative clinical trial of sequential treatments of severe malaria with artesunate suppository followed by mefloquine in Thailand. Arm J. Trop. Med. Hyg. (1997) 57 (3):348–353.
   Google Scholar
• CAO XT, BETHELL DB, PHAM TP eta].: Comparison of artemisinin suppositories, im. artesunate and iv. qui-nine for the treatment of severe childhood malaria. Trans. R. Soc. Trop. Med. Hyg. (1997) 91(3):335–342.
   Google Scholar
• LOOAREESUWAN S, WILAIRATANA P, VANIJANONTA S, VIRAVAN C, ANDRIAL M: Efficacy and tolerability of a sequential, artesunate suppository plus mefloquine, treatment of severe falciparum malaria. Ann. Trop. Med. Parasitol. (1995) 89(5):469–475.
   PubMed Web of Science ®Google Scholar
• LI GQ, GUO XB, FU LC, JIAN HX, WANG XH: Clinical tri-als of artemisinin and its derivatives in the treatment of malaria in China. Trans. Roy. Soc. Trop. Med. Hyg. (1994) 88 (Suppl. 1):5–6.
   Google Scholar