Bibliography
- FURCHGOTT RF, ZAWADZKI JV: The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature (1980) 288:373–376.
- •Description of the discovery of EDRF by Nobel Prize winner RF Furchgott
- IGNARRO LJ, BUGA GM, WOOD KS, BYRNS RE, CHAUDHURI G: Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc. Nati Acad. ScL USA (1987) 84:9265–9269.
- •Identification of NO as EDRF by Nobel Prize winner L Ignarro.
- PALMER RMJ, FERRIGE AG, MONCADA S: Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature (1987) 327:524–526.
- •First publication describing the identification of NO as EDRF.
- MONCADA S, HIGGS A: The L-arginine-nitric oxide pathway. New Engl. J. Med. (1993) 329:2002–2012.
- ••Review of the role of nitric oxide in normal physiology anddisease.
- MURAD F: The nitric oxide-cyclic-GMP signal transduc- tion system for intracellular communication. Recent Progress in Hormone Research (1994) 49:239–248.
- •Review of the role of cGMP in nitric oxide signal transduc-tion by Nobel Prize winner F Murad.
- HUANG F-P, NIEDBALA W, WET X-Q et al: Nitric oxide regulates Thl cell development through the inhibition of IL-2 synthesis by macrophages. Eur. J. Immunol (1998) 28:4062–4070.
- MARLETTA MA: Nitric oxide synthase structure and mechanism. J. Biol. Chem. (1993). 268:12231–12234.
- CRANE BR, ARVAI AS, WU C et al: The structure of nitric oxide synthase oxygenase domain and inhibitor complexes. Science (1997) 278:425–431.
- CALVER A, COLLIER J, VALLANCE P: Nitric oxide and cardiovascular control. Exp. Physiol. (1993) 78:303–326.
- WARREN JB, PONS F, BRADY AJB: Nitric oxide biology: implications for cardiovascular therapeutics. Cardio-vasc. Res. (1994) 28:25–30.
- SANDERS PW: Role of nitric oxide in regulation of blood pressure. J. Nephrol. (1992) 5:23–30.
- PARRAT JR: Nitric oxide: a key mediator in sepsis and endotoxaemia. J. Physiol. Pharmacol. (1997) 48:493–505.
- SZABO C: Alterations in nitric oxide production in various forms of circulatory shock. New Horizons (1995) 3:2-32. Review of the role of nitric oxide in septic shock.
- THOMSEN LL, LAWTON FG, KNOWLES RG, BEESLEY JE, RIVEROS-MORENO V, MONCADA S: Nitric oxide synthase activity in human gynecological cancer. Cancer Res. (1994) 54:1352–1354.
- AMBS S, MERRIAM WG, BENNETT et al: Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression. Cancer Res. (1998) 58:334–341.
- HIBBS JR,TAINTOR RR, VAVRIN Z, RACHLIN EM: Nitric oxide: a cytotoxic activated macrophage effector molecule. Biochem. Biophys. Res. Commun. (1988) 157:87–94.
- JENKINS DC, CHARLES IG, THOMSEN LL et al.: Roles ofnitric oxide in tumour growth. Proc. Natl. Acad. Sci. USA (1995) 92:4392–4396.
- ZICHE M, MORBIDELLI L, MASINI E et al: Nitric oxidemediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P. J. Clin. Invest. (1994) 94:2036–2044.
- AMBS S, HUSSAIN SP, HARRIS CC: Interactive effects ofnitric oxide and the p53 suppressor gene in carcino-genesis and tumour progression. FASEB 1 (1997) 11:443–448.
- BUTLER AR, FLITNEY FW, WILLIAMS DLH: NO, nitrosium ions, nitrosothiols and iron-nitrosyls in biology: a chemists perspective. TIPS (1995) 16:18–22.
- •Useful review of the chemistry of nitric oxide relevant to its biological function.
- FUKOTO JM, WINK DA: Nitric oxide (NO): Formation and biological roles in mammalian systems. In: Metal Ions in Biological Systems (Vol. 36). Interrelations between free radicals and metal ions in life processes. Sigel A, Sigel H (Eds), Marcel Dekker Inc., New York (1999):547–595.
- ••Review of the biological roles of nitric oxide from achemistry perspective.
- HENRY Y, LEPOIVRE M, DRAPIER J-C, DUCROQ C, BOUCHER J-L, GUISSANI A: EPR characterisation of molecular targets for NO in mammalian cells and organelles. FASEB J (1993) 7:1124–1134.
- DA WINK, JF DARBYSHIRE, RW NIMS, JE SAAVEDRA, PC FORD: Reactions of the bioregulatory agent nitric oxide in oxygenated aqueous media: determination of the kinetics for oxidation and nitrosation by interme-diates generated in the NO/02 reaction. Chem. Res. Toxicol (1993) 6:23–27.
- FREEMAN B: Free radical chemistry of nitric oxide. Looking at the dark side. Chest (1994) 105:79S–845.
- RICHTER-ADO GG, LEGZDINS P: Metal Nitrosyls. Oxford University Press, New York (1992).
- •Book describing the chemistry of metal complexes of nitric oxide.
- LIPTON SA, CHOI Y-B, P Z-H et al.: A redox-basedmechanism for the neuroprotective and neurode-structive effects of nitric oxide. Nature (1993) 364:626–631.
- SCHMIDT HHH, HOFMAN H, SCHINDLER U, SHUTENKOZS, CUNNINGHAM DD, FEELISCH M: No NO from NO synthase. Proc. Natl. Acad. Sci. USA (1996) 93:14492–14497.
- PUFAHL RA, WISHNOK JS, MARLETTA MA: Hydrogen peroxide-supported oxidation of NG-hydroxy-L--arginine by nitric oxide synthase. Biochemistry (1995) 34:1930–1941.
- FEELISCH M, TE POEL M, ZAMORA R, DEUSSEN A, MONCADA S: Understanding the controversy over the identity of EDRF. Nature (1994) 368:62–65.
- WINK DA, FEELISCH M, FUKOTO J et al. The cytotoxicity of nitroxyl: possible implications for the pathophysiological role of NO. Arch. Biochem. Biophys. (1998) 351:66–74.
- KERWIN JF, LANCASTER JR., FELDMAN PL: Nitric oxide: a new paradigm for second messengers. J. Med. Chem. (1995) 38:4343–4361.
- •Review describing the role of nitric oxide in disease and therapeutic approaches.
- MARLETTA MA: Approaches towards selective inhibi- tion of nitric oxide synthase. J. Med. Chem. (1994) 37:1899–1907.
- •A review of the chemistry of NOS inhibitors.
- KILBOURN RG, SZABO C, TRABER DL: Beneficial versus detrimental effects of nitric oxide synthase inhibitors in circulatory shock: lessons learned from experi-mental and clinical studies. Shock (1997) 7:235–246.
- ••Review of preclinical and clinical studies with NOSinhibitors.
- FAN B, WANG J, STUEHR DJ, ROUSSEAU DL: NO synthase isoenzymes have distinct substrate binding sites. Biochemistry (1997) 36:12660–12665.
- FRICKER SP: Nitrogen monoxide mediated disease and nitrogen monoxide scavengers as potential drugs. In: Metal Ions in Biological Systems (Vol. 36). Interrelations between free radicals and metal ions in life processes. Sigel A, Sigel H (Eds), Marcel Dekker, Inc., New York (1999):665–721.
- ••Review of nitric oxide scavengers.
- AKAIKE T, YOSHIDA M, MIYAMOTO Y: Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/NO through a radical reaction. Biochemistry (1993) 3:827–832.
- MAEDA H, AKAIKE T, YOSHIDA M, SUGA M: Multiplefunctions of nitric oxide in pathophysiology and microbiology: analysis by a new nitric oxide scavenger. J. Leukocyte Biol. (1994) 57:588–592.
- •Review of the pharmacology of PTIO derivatives.
- YOSHIDA M, AKAIKE T, WADA Y, SATO K, IKEDA K, UEDA S, MAEDA H: Therapeutic effects of imidazoline-oxyl N-oxide against endotoxin shock through its direct nitric oxide scavenging activity. Biochem. Biophys. Res. Commun. (1994) 202:923–930.
- MAEDA H, NOGUCHI Y, SATO K, AKAIKE T: Enhancedvascular permeability in solid tumor is mediated by nitric oxide and inhibited by both new nitric oxide scavenger and nitric oxide synthase inhibitor. Jpn. J. Cancer Res. (1994) 85:331–334.
- WU J, AKAIKE T, MAEDA H: Modulation of enhancedvascular permeability in tumours by a bradykinin antagonist, a cyclooxygenase inhibitor, and a nitric oxide scavenger. Cancer Res. (1998) 58:159–165.
- VEROVSKI VN, VAN DEN BERGE DL, SOETE GA, BOLS BL,STORME GA: Intrinsic radiosensitivity of human pancreatic tumour cells and the radiosensitising potency of the nitric oxide donor sodium nitroprus-side. Br. J. Cancer (1996) 74:1734–1742.
- TOZER GM, PRISE VE, CHAPLIN DJ Inhibition of nitric oxide synthase induces a selective reduction in tumor blood flow that is reversible with L-arginine. Cancer Res. (1997) 57:948–955.
- PAISLEY K, MARTIN W: Blockade of nitrergic transmis- sion by hydroquinone, hydroxocobalamin and carboxy-PTIO in bovine retractor penis: role of superoxide anion. Br. J. Pharmacol. (1 9 9 6) 117:1633-1638.
- DOYLE MP, HOEKSTRA JW: Oxidation of nitrogen oxides by bound dioxygen in hemoproteins. J. Inorg. Biochem. (1981) 14:351–358.
- GOW AJ, STAMLER JS: Reactions between nitric oxideand haemoglobin under physiological conditions. Nature (1998) 391:169–173.
- FISCHER SR, BONE HG, TRABER DL: Effects ofhemoglobin in sepsis. In: Yearbook of Intensive Care and Emergency Medicine 1997. Vincent J-L (Ed.), Springer-Verlag, Heidelberg, Germany (1997):424–44.
- •Review of haemoglobin as a nitric oxide scavenger.
- KILBOURN RG, JOLY G, CASHON B, DEANGELO J, BONAVENTURA J: Cell-free hemoglobin reverses the endotoxin-mediated hyporesponsivity of rat aortic rings to a-adrenergic agents. Biochem. Biophys. Res. Commun. (1994) 199:155–162.
- BONE HG, SCHENARTS PJ, BOOKE M et al.: Oxalated pyridoxalated hemoglobin polyoxyethylene conjugate normalizes the hyperdynamic circulation in septic sheep. Crit. Care Med. (1997) 25:1010–1018.
- BONE HG, FISCHER SR, SCHENARTS PJ, MCGUIRE R, TRABER L, TRABER DL: Continuous infusion of pyridox-alated hemoglobin polyoxyethylene conjugate in hyperdynamic septic sheep. Shock (1998) 10:69–76.
- KILBOURN RG, DEANGELO J, BONAVENTURA J: Clinical effects of cell-free hemoglobin, a scavenger of nitric oxide, in septic shock. In: Yearbook of Intensive Care and Emergency Medicine 1997. Vincent J-L (Ed.) Springer-Verlag, Heidelberg, Germany (1997):230–239.
- BUTLER AR, GLIDEWELL C: Recent chemical studies of sodium nitroprusside relevant to its hypotensive action. Chem. Soc. Rev. (1987) 16:361–380.
- RAJANAYGAM MAS, LI CG, RAND MJ: Differential effects of hydroxocobalamin on NO-mediated relaxations in rat aorta and anococcygeus muscle. Br. J. Pharmacol. (1993) 108:3–5.
- GREENBERG S, XIE J, ZATARAIN JM, KAPUSTA DR MILLER MJS: Hydroxocobalamin (vitamin B12a) prevents and reverses endotoxin-induced hypotension and mortality in rodents: role of nitric oxide. (1995) J. Pharmacol. Exp. Ther. (1995) 273:257–265.
- •Description of the NO scavenging properties of hydoxocobalamin.
- KAZMIERSKI WM, WOLBERG G, WILSON JG et al.: Iron chelates bind nitric oxide and decrease mortality in an experimental model of septic shock. Proc. Natl. Acad. Sci. USA (1996) 93:9138–9141.
- MOLINA L, STUDENBERG S, WOLBERG G et al: Efficacy of treatment with the iron (III) complex of diethylene-triamine pentaacetic acid in mice and primates inoculated with live lethal dose 100 Escherichia Cli. Invest. (1996) 98:192–198.
- LAI C-S, KOMAROV A: Spin trapping of nitric oxide produced in vivo in septic-shock mice. FEBS Letter (1994) 345:120–124.
- KOMAROV A, LAI C-S: Detection of nitric oxide produc-tion in mice by spin-trapping electron paramagnetic resonance spectroscopy. Biochim. Biophys. Acta (1995) 1272:29–36.
- MIKOYAN VD, KUBRINA LN, SEREZHENKOV VA, STUKANRA, VANNIN AF: Complexes of Fe2+ with diethyldithio-carbamate or N-methyl-D-glucamine dithiocarbamate as traps of nitric oxide in animal tissues: comparative investigations. Biochim. Biophys. Acta (1 9 9 7) 1336:225–234.
- PIEPER GM, LAI C-S: Evaluation of vascular actions ofthe nitric oxide-trapping agent, N-methyl-D-glucamine dithiocarbamate-Fe2±, on basal and agonist-stimulated nitric oxide activity. Biochem. Biophys. Res. Commun. (1996) 219:584–590.
- •Description of the pharmacological activity of an iron dithio-carbamate NO scavenger.
- COOPER M, DEMBNY K, LINDHOLM P et al.: Effects ofnitric oxide scavenging and inhibition of NF-KB activity on cardiac allograft survival. Surg. Forum (1997) 48:500–503.
- PIEPER, DEMBNY K, SIEBENEICH W: Long-termtreatment in vivo with NOX-101, a scavenger of nitric oxide, prevents diabetes-induced endothelial dysfunc-tion. Diabetologia (1998) 41:1220–1226.
- FRICKER SP: Ruthenium, nitric oxide and disease. Plainum. Metals Rev. (1995) 39:150–159.
- BOTTOMLEY F: Nitrosyl complexes of ruthenium. Coord. Chem. Rev. (1978) 26:7–32.
- ••Review of the chemistry of ruthenium-nitric oxidecompounds.
- DAVIES NA, WILSON MT, SLADE E et al.: Kinetics of nitricoxide scavenging by ruthenium III) polyaminocar-boxylates: novel therapeutic agents for septic shock. Chem. Commun. (1997):47–48.
- FRICKER SP, SLADE E, POWELL NA et al.: Ruthenium complexes as nitric oxide scavengers: a potential therapeutic approach to nitric oxide-mediated diseases. Br. J. Pharmacol (1997) 122:1441–1449.
- ••Description of the NO scavenging properties of rutheniumcompounds.
- FINK MP, O'SULLIVAN BP, MENCONI MJ: A novel leukotriene B4-receptor antagonist in endotoxin shock: a prospective, controlled trial in a porcine model. Crit. Care. Med. (1993) 21:1825–1837.
- ARANOW JS, WANG H, ZHUANG J, FINK MP: Effect ofhemoglobin on systemic and regional hemodynamics in a porcine model of endotoxemic shock. Grit. Care Med. (1996) 24:807–814.
- BAGGS AG, FRICKER S, ABRAMS M, LEE C, FINK MP: Anovel ruthenium-based nitric oxide scavenger ameliorates acute lung injury in porcine endotoxemia. Surg. Forum (1997) 48:84–86.
- BOOKE M,MEYER M, LINGAU W, HINDER F, TRABER LD, TRABER DL: Use of nitric oxide synthase inhibitors in animal models of sepsis. NewHorizons (1995) 3:123–138.