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Review

Transcription therapy for acute promyelocytic leukaemia

Pages 329-346 | Published online: 24 Feb 2005

Bibliography

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  • ••Although somewhat out of date, it contains a detailedpractical review on the principals of clinical usage of ATRA in APL.
  • WARRELL RP JR, FRANKEL SR, MILLER WH JR et al.: Differ-entiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid). N Engl. J. Med. (1991) 324:1385–1393.
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  • •A large study describing the ATRA syndrome in the European APL93 clinical trial and a good review of the litera-ture on this complication.
  • TALLMAN MS, ANDERSEN JW, SCHIFFER CA et al.: All-trans-retinoic acid in acute promyelocytic leukemia. N Engl. J. Merl. (1997) 337:1021–1026.
  • •The results on the randomised U.S. intergroup APL trial.
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  • FENAUX P, CHASTANG C, CHEVRET S et al.: A random-ized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia. Blood (1999) 94:1192–1200.
  • •The results of the European APL93 clinical trial and review of the literature of treatment of this disease.
  • ASOU N, ADACHI K, TAMURA J et al.: Analysis of prognostic factors in newly diagnosed acute promye-locytic leukemia treated with all-trans retinoic acid and chemotherapy. J. Clin. Oncol (1998) 16:78–85.
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  • LO COCO F, DIVERIO D, AVVISATI G et al.: Therapy of molecular relapse in acute promyelocytic leukemia. Blood (1999) 94:2225–2229.
  • •Using the PCR to detect minimal residual disease in APL, to define the goal of treatment as PCR negativity for the fusion gene and how to treat patients who are PCR positive.
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