25
Views
6
CrossRef citations to date
0
Altmetric
Review

Gene therapy and heart transplantation

, &
Pages 1021-1027 | Published online: 24 Feb 2005

Bibliography

  • WETS M, MEISER BM, REICHART B, VON SCHEIDT W: The continuing challenge of cardiac transplant arterioscle-rosis. Cardiologia (1998) 43:777–787.
  • HARRISON RL, BYRNE BJ, TUNG L: Electroporation mediated gene transfer in cardiac tissue. FEBS Letters (1998) 435:1–5.
  • TANNER FC, CARR DP, NABEL GJ, NABEL EG: Transfec-tion of human endothelial cells. Cardiovascular Res. (1997) 35:522–528.
  • ZELENIN AV, TARASENKO OV, KOLESNIKOV VA et al.: Expression of the human dystrophin gene in mdx mouse skeletal muscles after ballistic transfection. Genetika (1998) 34:730–736.
  • CHENG PW: Receptor ligand-facilitated gene transfer: enhancement of liposome-mediated gene transfer and expression by transferrin. Hum. Gen. Ther. (1996) 7:275–282.
  • ELLISON KE, BISHOPRIC NH, WEBSTER KA et al.:Fusigenic liposome-mediated DNA transfer into cardiac myocytes. J. Mol. Cell. Cardiol. (1996) 28:1385–1399.
  • RIVIERE I, SADELAIN M: Methods for the construction of retroviral vectors and the generation of high-titre producers. In: Gene Therapy Protocols. Robbins P (Ed.) Humana Press, Inc., Totowa, NJ, USA (1995):59–78.
  • JANE SM, CUNNINGHAM JM, VANIN EF: Vector develop-ment: a major obstacle in human gene therapy. Ann. Med. (1998) 30:413–415.
  • •A good overview of current technical limitations of gene transfer methods.
  • YAP J, O'BRIEN T, TAZELAAR HD, MCGREGOR CGA:Immunosuppression prolongs adenoviral mediated transgene expression in cardiac allograft transplanta-tion. Cardiovascular Res. (1997) 35:529–535.
  • YANG Y, LI Q, ERTL HC, WILSON JM: Cellular andhumoral responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. j Vim]. (1995) 69:2004–2015.
  • FERRY N, HEARD JM: Liver-directed gene transfervectors. Hum. Gen. Ther. (1998) 9:1975–1981.
  • SCHIEDNER G, MORRAL N, PARKS RJ et al.: Genomic DNA transfer with a high capacity adenovirus results in improved gene expression and decreased toxicity. Nature Genet. (1998) 18:180–183.
  • WOLFFE JA, MALONE RW, WILLIAMS P et al: Direct gene transfer into mouse muscles in vivo. Science (1990) 247:1465–1468.
  • •Classic demonstration of somatic gene transfer and expression.
  • LIN H, PARMACEK MS, MORLE G, BOLLING S, LEIDEN JM:Expression of recombinant genes in myocardium in vivo after direct injection of DNA. Circulation (1990) 82:2217–2221.
  • KITRIS RN, BUTTRICK PM, MCNALLY EM, KAPLAN ML,LEINWALD LA: Harmonal modulation of a gene injected into rat heart in vivo. Proc. Natl. Acad. Sci. USA (1991) 88:4138–4142.
  • GAL G, WEIR L, LECLERC G et al.: Direct myocardialtransfection in two animal models. Lab. Invest. (1993) 68:18–25.
  • ARDEHALI A, FYFE A, LAKS H, DRINKWATER DC, QIAO J,LUSIS AJ: Direct gene transfer into donor hearts at the time of harvest. J. Thorac Cardiovasc. Surg. (1995) 109:716–720.
  • FYFE M, ARDEHALI A, LAKS H, DRINKWATER DC, LUSIS AJ: Biologic modification of the immune response in mouse cardiac isografts using gene transfer. J. Heart Lung Transplant (1995) 14:165–170.
  • LEE J, LAKS H, DRINKWATER DC et al.: Cardiac gene transfer by intracoronary infusion of adenovirus vector mediated reporter gene in the transplanted mouse heart. J. Thorac Cardiovasc. Surg. (1996) 111:246–252.
  • DEBRUYNE PW, LI K, CHAN SY, QIN L, BISHOP DK, BROMBERG JS: Lipid-mediated gene transfer of viral IL-10 prolongs vascularized cardiac allograft survival by inhibiting donor-specific cellular and humoral immune response. Gene Therapy (1998) 5:1079–1087.
  • ••This study demonstrates that viral IL-10 gene transfer canmodulate graft rejection and offers mechanisms for its effects.
  • BRAUNER R, WU L, LAKS H et al: Intracoronary genetransfer of immunosuppressive cytokines to cardiac allografts: method and efficacy of adenovirus-mediated transduction. J. Thorac Cardiovasc. Surg. (1997) 113:1059–1067.
  • KITA Y, LI X K, HAYASHI S et al.: Prolonged rat cardiacallograft survival using adenoviral vector containing the CTL4Ig gene. Transplant Proc. (1998) 30:1079–1080.
  • POSTON RS, ENNEN M, POLLARD J, HOYT EG, BILLINGHAM ME, ROBBINS RC: Ex vivo gene therapy prevents chronic graft vascular disease in cardiac allografts. J. Thorac Cardiovasc. Surg (1998) 116:386–396.
  • ZELPHATI O, LIANG X, HOBART P, FELGNER PL: Genechemistry: functionally and confirmationally intact flourescent plasmid DNA. Hum. Gene Ther. (1999) 10:15–24.
  • EGHOLM M, BUCHARDT O, CHRISTENSEN L et al: PNAhybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules. Nature (1993) 365:566–568.
  • WONG W, FRY J, HYDE K, STRANFORD S, MORRIS PJ,WOOD KJ: Haematopoietic stem cells transduced with a single donor class I major histocompatibility complex gene can induce operational tolerance to fully allogeneic cardiac allografts. Transplant Proc. (1999) 31:886.
  • HANCOCK WW, BURLOW R, SAYEGH MH, TURKA LA: Antibody induced transplant ateriosclerosis is prevented by graft expression of anti-oxidant and anti apoptotic genes. Nature Med. (1998) 4:1392–1396.
  • COOPER JT, STROKA DM, BROSTJAN C, PALMETSHOFERA, BACH FH, FERRAN C: A 20 blocks endothelial cell activation through a NF-Kappa B-dependent mechanism. J. Biol. Chem. (1996) 271:18068–18073.
  • QIN L, CHAVIN KD, DING Y et al.: Gene transfer fortransplantation; prolongation of allograft survival with transforming growth factor-Bl. Ann. Surg. (1994) 220:508–519.
  • QIN L, CHAVIN KD, DING Y et al.: Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac allograft survival. J. Immunol. (1996) 156:2316–2323.
  • YANG Z, ROSTAMI S, KOEBERLEIN B, BARKER CF, NAJI A: Cardiac allograft tolerance induced by intra-arterial infusion of recombinant adenoviral CTLA4Ig. Transplantation (1999) 67:1517–1523.
  • •A study of application of gene transfer technology to local co-stimulating blockade mediated tolerance.
  • IERINO FL, GOJO S, BANERJEE PT et al.: Transfer of swine major histocompatibility complex class II genes into autologous bone marrow cells of baboons for the induction of tolerance across xenogenic barriers. Transplantation (1999) 67:1119–1128.
  • SASAKI H, XU X C, SMITH DM, HOWARD T, MOHANKUMAR T: HLA-G expression protects porcine endothelial cells against natural killer cell-mediated xenogenic cytotoxicity. Transplantation (1999) 67:31–37.
  • BACH FH, SOARES M, LIN Y, FERRAN C: Barriers to Xenotransplantation. Transplant Proc. (1999) 31:1819–1820.
  • BRENNER MK, HESLOP HE, RILL D et al.: Transfer of marker genes into hemopoietic progenitor cells. Cytokines Mol. Ther. (1996) 2:193–200.
  • LOSORDO DW, VALE PR, SYMES JF et al.: Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of ph VEGF 165 as sole therapy for myocardial ischemia. Circulation (1998) 98:2800–2804.
  • •The result of a Phase I clinical study to determine the safety and bioactivity of VEGF in patients with ischaemic heart disease.
  • ROSENGART TK, LEE LY, PATEL SR et al.: Angiogenesis gene therapy: Phase I assessment of direct intramyo-cardial administration of an adenoviral vector expressing VEGF 121 cDNA to individuals with clinically significant severe coronary artery disease. Circulation (1999) 100:468–474.
  • LOSORDO DW, VALE PR, ISNER JM: Gene therapy for myocardial angiogenesis. Am. Heart J. (1999) 138:132–141.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.